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1. 发明申请

WO01097901A2 MICRO-INJECTION PUMP 审中-公开
标题翻译：微型注射泵
公开(公告)号：WO01097901A2
公开(公告)日：2001-12-27
申请号：PCT/US2001/019676
申请日：2001-06-20
IPC分类号： A61M5/00 , A61M5/145 , A61M5/168 , A61M5/172 , A61M500
CPC分类号： A61M5/172 , A61M5/007 , A61M5/1452 , A61M5/168 , A61M5/16827 , A61M2205/50
摘要： A micro-injection pump (10) for angiography and micro-intervention procedures comprises first and second linear traverses (12, 14) each having a pusher element (12F, 14F) movable by stepper motor drive (12D, 14D) for controlling discharge from a respective micro-syringe (16, 20) engaged by the pusher element (12F, 14F). The first micro-syringe (16) preferably contains a volume of a soluble contrast medium (18), and the second micro-syringe preferably contains a volume of an insoluble contrast medium (22). Fluid discharged by the micro-syringes (16, 20) is directed to a bifurcated micro-droplet generator (28) having a straight primary passage (30D) and an obliquely merging tributary passage (30E). Insoluble contrast medium (22) from the second micro-syringe (20) flows through a micro-sized injection needle (34) extending partially and coaxially within the primary passage (30D) to a termination point just downstream from where the tributary passage (30E) joins the primary passage (30D). Soluble contrast medium (18) from the first micro-syringe (16) passes through the tributary passage (30E) to provide a flow field surrounding the injection needle (34) for shearing off discrete same-sized boluses (22A) from the terminal tip of the injection needle (34) at regular frequency in coordination with a predetermined motion profile of the first and second linear traverses (12, 14). Motion control of the linear traverses is possible using LABVIE3 virtual instrumentation software arranged to communicate with a 2-axis indexer control (58) connected to first and second motor indexers (46, 50) for driving the stepper motors (12D, 14D) of the linear traverses (12, 14). Linear potentiometers (84, 86) on the linear traverses (12, 14), rotary encoders (85, 87) connected to the motors (12D, 14D), a flowmeter (92), and pressure transducers (88, 90) indicate motion and flow parameters of the system in real-time to provide a feedback loop in the system so that a desired media delivery waveform is realized.
摘要翻译：用于血管造影和微观介入程序的微型注射泵（10）包括第一和第二线性横移（12,14），每个具有可由步进电机驱动器（12D，14D）移动的推动元件（12F，14F），用于控制从由推动元件（12F，14F）接合的相应的微型注射器（16,20）。第一微型注射器（16）优选地包含一定体积的可溶性造影剂（18），并且第二微型注射器优选地包含一定体积的不溶性造影剂（22）。通过微型注射器（16,20）排出的流体被引导到具有直的主要通道（30D）和倾斜并入的支流通道（30E）的分叉的微滴发生器（28）。来自第二微型注射器（20）的不溶性造影剂（22）流过在主要通道（30D）内部分和同轴延伸的微型注射针（34），直到下游的终止点，其中支流通道（30E ）连接主通道（30D）。来自第一微型注射器（16）的可溶性造影剂（18）通过支流通道（30E），以提供围绕注射针（34）的流场，用于从终端尖端剪切离散的相同大小的弹丸（22A）以与第一和第二线性横移（12,14）的预定运动曲线协调的规则频率的注射针（34）。使用安装成与连接到第一和第二电动机分度器（46,50）的2轴分度器控制（58）通信的LABVIE3虚拟仪器软件来实现线性运动的运动控制，用于驱动步进马达（12D，14D）线性横移（12,14）。连接到马达（12D，14D）的直线运动（12,14），旋转编码器（85,87）上的线性电位器（84,86），流量计（92）和压力传感器（88,90）指示运动和系统的流量参数，以在系统中提供反馈回路，从而实现期望的介质输送波形。

2. 发明授权

US06796970B1 Dose setting device 失效
标题翻译：剂量设定装置
公开(公告)号：US06796970B1
公开(公告)日：2004-09-28
申请号：US09090144
申请日：1998-06-04
申请人： Lars Peter Klitmose , Henrik Andersen , Preben Broskov Nielsen , John Thrane Hansen
发明人： Lars Peter Klitmose , Henrik Andersen , Preben Broskov Nielsen , John Thrane Hansen
IPC分类号： A61M500
CPC分类号： A61M5/315 , A61M5/24 , A61M5/3146 , A61M5/31511 , A61M5/31525 , A61M5/31543 , A61M5/31553 , A61M5/31556 , A61M5/31558 , A61M5/31563 , A61M5/31571 , A61M5/31575 , A61M5/3158 , A61M5/31593 , A61M5/31595 , A61M2005/14573 , A61M2005/31518 , B05C17/0113 , Y10S128/01
摘要： A dose setting device for a delivery system has a piston rod (6, 9) which successively presses a piston (2) into a cylinder ampoule (1). Doses are set by rotating a second part (9) of the piston rod (6, 9) in relation to a first part (6). The two parts are connected by mating threads so that the total length of the piston rod (6, 9) is increased proportional to the angle of rotation, and a point (18) on the second part is moved away from a stop position fixed in relation to a housing (5) The set dose is delivered when the point (18) is moved back to the stop position. The first part (6) can be axially displaced but not rotated in the housing (5), and the second part (9) can both rotate and be axially displaced. The first part (6) is maintained in abutment with the piston (2) and the second part (9) is coupled to be rotated by a dose setting wheel (20). An injection push button (10) is movable between a projecting position and a pressed home position and has elements (13) acting on the second part (9) to press this part to its stop position.
摘要翻译：用于输送系统的剂量设定装置具有连续地将活塞（2）压入气缸安瓿（1）中的活塞杆（6,9）。通过相对于第一部分（6）旋转活塞杆（6,9）的第二部分（9）来设定剂量。两个部件通过配合螺纹连接，使得活塞杆（6,9）的总长度与旋转角成比例地增加，并且第二部件上的点（18）移动离开固定在与外壳的关系（5）当点（18）移回到停止位置时，传送设定的剂量。第一部分（6）可以在壳体（5）中轴向移位但不旋转，并且第二部分（9）都可以旋转并且被轴向移位。第一部分（6）保持与活塞（2）邻接，并且第二部分（9）被联接以由剂量设定轮（20）旋转。注射按钮（10）能够在突出位置和被按压的原始位置之间移动，并且具有作用在第二部分（9）上的元件（13）以将该部分按压到其停止位置。

3. 发明授权

US06783514B2 Fibrin sealant applicator 失效
标题翻译：纤维蛋白胶密封胶
公开(公告)号：US06783514B2
公开(公告)日：2004-08-31
申请号：US08792535
申请日：1997-01-31
申请人： H. Johnathan Tovey , Ernie Aranyi , Vinod C. Nagori , Stanley Marczyk
发明人： H. Johnathan Tovey , Ernie Aranyi , Vinod C. Nagori , Stanley Marczyk
IPC分类号： A61M500
CPC分类号： A61B17/00491 , A61B2017/00495
摘要： An applicator is provided for dispensing a first and a second component of a biological adhesive. The applicator includes a housing having a housing head for enclosing therein a first reservoir containing the first component, and a second reservoir containing the second component. The housing further includes an elongated body portion defining a longitudinal axis for enclosing therein a conduit assembly having a first and a second conduit in communication with the first and second reservoir, respectively. An activator assembly is provided which includes an activator and a rachet mechanism for compressing the reservoirs within the housing for dispensing the biological components into the conduits. An applicator tip having two separate channels in communication with the conduits may be provided on a distal end of the elongated body portion for dispensing the components on the application site. The first and second components are preferably fibrinogen and thrombin which intermix to form a fibrin sealant.
摘要翻译：提供了用于分配生物粘合剂的第一和第二组分的施用器。施加器包括壳体，该壳体具有壳体头部，用于在其中封装包含第一部件的第一储存器和容纳第二部件的第二储存器。壳体还包括限定纵向轴线的细长主体部分，用于在其中封闭具有分别与第一和第二储存器连通的第一和第二导管的导管组件。提供了一种活化器组件，其包括活化剂和用于压缩壳体内的储存器的冲洗机构，用于将生物组分分配到导管中。具有与管道连通的两个单独通道的施用器尖端可以设置在细长主体部分的远端上，用于在施加部位上分配部件。第一和第二组分优选纤维蛋白原和凝血酶混合以形成纤维蛋白密封剂。

4. 发明授权

US06773416B1 Safety hypodermic syringe 失效
标题翻译：安全皮下注射器
公开(公告)号：US06773416B1
公开(公告)日：2004-08-10
申请号：US10372132
申请日：2003-02-25
申请人： Fu-Yu Hsu
发明人： Fu-Yu Hsu
IPC分类号： A61M500
CPC分类号： A61M5/322 , A61M5/5066
摘要： A safety hypodermic syringe in which the plunger is detachably connected to the stopper by a hook joint so that when the user pulled the plunger backwards to carry the stopper and the needle assembly backwards to the inside of the barrel after the service of the syringe, the plunger is automatically disconnected from the stopper, leaving the stopper and the needle assembly inside the barrel.
摘要翻译：一种安全皮下注射器，其中柱塞通过钩接头可拆卸地连接到止动件，使得当用户在注射器服务之后向后拉动柱塞以将塞子和针组件向后运送到枪管的内部时，柱塞自动与止动器断开，将止动器和针组件留在机筒内。

5. 发明授权

US06770056B2 Dispensing device 失效
标题翻译：点胶装置
公开(公告)号：US06770056B2
公开(公告)日：2004-08-03
申请号：US10182296
申请日：2002-08-22
申请人： Phil T. Price , Stephanie Bley , Bernard Sams
发明人： Phil T. Price , Stephanie Bley , Bernard Sams
IPC分类号： A61M500
CPC分类号： G01F11/023
摘要： A device for dispensing a measured dose of liquid from an attached container which container has an elongate casing defining a dispensing cylinder, one end of the casing being adapted for mounting on the container. A plurality of dose indications are provided on the external surface of the casing so that a dose may be pre-selected by moving a dose setting collar along the casing. The collar has a stop engageable with a selected one of a multiplicity of recesses on the casing to secure the collar at the required position. A plunger having a piston co-operating with a cylinder defined by the casing is movable to lift the piston from said one end of the casing until the piston abuts the dose setting collar so charging the dispenser. Depression of the plunger to move the piston back to said one end dispenses the selected dose from an outlet port.
摘要翻译：一种用于从连接的容器分配测量剂量的液体的装置，该容器具有限定分配筒的细长壳体，壳体的一端适于安装在容器上。在壳体的外表面上提供多个剂量指示，以便可以通过沿着套管移动剂量设定颈圈来预选剂量。套环具有可与壳体上的多个凹部中的所选择的一个接合的止动件，以将套环固定在所需位置。具有与由壳体限定的气缸配合的活塞的柱塞可移动，以从壳体的一端提升活塞，直到活塞抵靠剂量设定套环，从而对分配器进行充电。柱塞的凹陷将活塞移回所述一端从出口口分配所选择的剂量。

6. 发明授权

US06755804B2 Needle holder for use with safety needle assembly 有权
标题翻译：针座用于安全针组件
公开(公告)号：US06755804B2
公开(公告)日：2004-06-29
申请号：US10173952
申请日：2002-06-17
申请人： Jamieson William Maclean Crawford
发明人： Jamieson William Maclean Crawford
IPC分类号： A61M500
CPC分类号： A61B5/150893 , A61B5/15003 , A61B5/150351 , A61B5/150389 , A61B5/150473 , A61B5/150572 , A61B5/150587 , A61B5/150595 , A61B5/15061 , A61B5/150633 , A61B5/150717 , A61B5/150732 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/154 , A61M2005/3212
摘要： A needle holder for use with a needle assembly for blood collection is provided, and in particular, for use with a needle assembly including an activation mechanism adapted for axial displacement between a first position and a second position with respect to the needle assembly through engagement with a blood collection tube. The needle holder includes an outer body having a first end adapted for attachment to such a needle assembly and a second end having an internal opening therein. The needle holder is adapted for accommodating a blood collection tube within the internal opening for engagement with the needle assembly. The needle holder further includes a lever which is movable between a first blocking position in which the activation mechanism is blocked from engagement with the blood collection tube to prevent axial movement from the first position to the second position, and a second release position in which the activation mechanism is capable of engagement with the blood collection tube to permit axial movement between the first position and the second position. The needle holder is particularly useful with needle assemblies including a blunting element which can be activated by the activation mechanism.
摘要翻译：提供了一种用于采集针头组件的针头保持器，并且特别地，用于针组件，所述针组件包括适于通过与第一位置和第二位置之间的轴向位移相对于针组件通过与采血管。针保持器包括外主体，其具有适于附接到这种针组件的第一端和在其中具有内部开口的第二端。针保持器适于将采血管容纳在内部开口内以与针组件接合。针架还包括杠杆，该杠杆可在第一阻挡位置和第二释放位置之间移动，在第一阻挡位置，致动机构被阻止与血液收集管的接合，以防止从第一位置向第二位置的轴向移动; 激活机构能够与采血管接合以允许在第一位置和第二位置之间的轴向移动。针架特别适用于针组件，其中包括能够被激活机构激活的钝化元件。

7. 发明授权

US06752782B2 Automatically retractable safety syringe 有权
标题翻译：自动伸缩安全注射器
公开(公告)号：US06752782B2
公开(公告)日：2004-06-22
申请号：US10108448
申请日：2002-03-29
申请人： Chin-Fu Liao
发明人： Chin-Fu Liao
IPC分类号： A61M500
CPC分类号： A61M5/3234 , A61M5/347
摘要： An automatically retractable safety syringe includes a needle assembly consisting of a cannula, a needle hub and a rubber O-ring, a needle cap, a retracting spring, a breakable and retractable plunger, a plunger gasket and a medicine barrel; in accordance with the structure of the said automatically retractable safety syringe of the present invention, since the breakable plunger is assembled inside the medicine barrel, after being pushed all the way to the end, it is forced to break automatically into two parts for reducing it's length so as to provide enough space for the retracting spring to drive the needle assembly moving along the sliding passages for accomplishing an automatically retracting action.
摘要翻译：一种可自动伸缩的安全注射器包括由套管，针座和橡胶O形环，针帽，收缩弹簧，可伸缩的柱塞，柱塞垫圈和药筒组成的针组件; 根据本发明的所述自动伸缩式安全注射器的结构，由于可拆卸的柱塞组装在药桶内，在被一直推到末端之后，被迫自动分解成两部分，以减少它的以便为回缩弹簧提供足够的空间来驱动针组件沿着滑动通道移动以实现自动缩回动作。

8. 发明授权

US06736794B2 Method and device to protect syringes and similar medical instruments 失效
标题翻译：保护注射器和类似医疗器械的方法和装置
公开(公告)号：US06736794B2
公开(公告)日：2004-05-18
申请号：US09995960
申请日：2001-11-27
申请人： Dietrich W. Grabis , Mary Anne Kaehler , Kenneth Mellberg
发明人： Dietrich W. Grabis , Mary Anne Kaehler , Kenneth Mellberg
IPC分类号： A61M500
CPC分类号： A61M5/3257 , A61M2005/3247 , Y10T29/53339
摘要： A needle-stick safety syringe includes an inner tubular body, plunger, and needle extending from a distal end of said inner tubular body, an outer tubular housing concentrically and slidingly surrounding at least a portion of the inner tubular body and biased apart from the inner tubular body. A recess is defined within an interior wall surface of the outer tubular housing, and a latch attached to a distal end of the inner tubular body. The latch includes a ring-shaped collar attached to the distal end of the inner tubular body and includes a cantilevered push-stop. A portion of the cantilevered push-stop is sized to fit within the recess when the latch is sufficiently disposed within the outer tubular housing.
摘要翻译：针刺安全注射器包括从所述内管体的远端延伸的内管状体，柱塞和针，外管状壳体同心且滑动地围绕内管体的至少一部分并且与内管管状体。在外部管状壳体的内壁表面内限定凹部，以及连接到内部管状体的远端的闩锁。闩锁包括附接到内管体的远端的环形套环，并且包括悬臂推动止动件。当闩锁被充分地设置在外部管状壳体内时，悬臂推动件的一部分的尺寸被设计成装配在凹部内。

9. 发明授权

US06733478B2 System and method for providing information from a syringe to an injector 失效
标题翻译：用于从注射器向注射器提供信息的系统和方法
公开(公告)号：US06733478B2
公开(公告)日：2004-05-11
申请号：US10287167
申请日：2002-11-04
申请人： David M. Reilly , Joseph B. Havrilla , Eugene A. Gelblum , Daniel Kazousky
发明人： David M. Reilly , Joseph B. Havrilla , Eugene A. Gelblum , Daniel Kazousky
IPC分类号： A61M500
CPC分类号： A61M5/14546 , A61M5/14566 , A61M2005/14553 , A61M2205/581 , A61M2205/582 , A61M2205/583 , Y10S128/01
摘要： A front-loading syringe which comprises a movable plunger for injecting liquid contrast media, is rotatably mountable on a front wall of an injector housing with an interference fit and in sealed relationship with respect thereto, with or without a pressure jacket, by a first-quick release mechanism. At the same time, the plunger is connected to an injector drive mechanism by a second readily releasable mechanism. During the mounting operation, a sensor reads injection information from an indicator device on the syringe and feeds it to an injector control. An audible-and-tactile indicating mechanism also is activated when the syringe is essentially in the desired mounted position. The syringe may include reinforcing ribs, which also function as volumetric gradations, and liquid media presence-or-absence indicating dots which appear circular against a liquid media background and oval-shaped against an air background. An injection end of the syringe comprises an injector portion of reduced diameter inside a screw-threaded attachment portion of larger diameter, and may include loop-shaped reinforcing handle portions.
摘要翻译：一种包括用于注射液体造影剂的活动柱塞的前装载注射器，可旋转地安装在喷射器壳体的前壁上，其具有过盈配合并且与其相关的密封关系，具有或不具有压力套，快速释放机制。同时，柱塞通过第二容易释放的机构连接到喷射器驱动机构。在安装操作期间，传感器从注射器上的指示器装置读取注射信息并将其馈送到注射器控制器。当注射器基本上处于所需的安装位置时，也可以触发听觉和触觉指示机构。注射器可以包括也用作体积灰度的加强肋，以及液体介质的存在或不存在，指示针对液体介质背景呈圆形并且与空气背景呈椭圆形的点。注射器的注射端部包括在较大直径的螺纹连接部分内的直径减小的注射器部分，并且可以包括环形加强手柄部分。

10. 发明授权

US06726663B1 Trocar with disposable valve and reusable cannula 有权
标题翻译：套管针与一次性阀和可重复使用的插管
公开(公告)号：US06726663B1
公开(公告)日：2004-04-27
申请号：US09523659
申请日：2000-03-10
申请人： William G. Dennis
发明人： William G. Dennis
IPC分类号： A61M500
CPC分类号： A61B17/3462 , A61B17/3417 , A61B17/3498 , A61B2017/0023 , A61B2017/0046
摘要： A modular trocar assembly having a cannula, a passive valve seal assembly and an instrument seal assembly all releasably joined to define a central axial bore, where the passive valve seal assembly contains a valve seal which prevents passage of gas through the trocar assembly into the atmosphere when no instrument is inserted but which opens to allow for insertion of an instrument, and where the instrument seal assembly contains an instrument reducer seal which prevents passage of gas through the trocar assembly into the atmosphere when an instrument is inserted through the valve seal. The passive valve seal assembly and the instrument seal assembly are preferably composed of plastic so as to be disposable, while the cannula is preferably composed of a sterilizable material to enable reuse.
摘要翻译：一种具有插管，被动阀密封组件和仪器密封组件的模块化套管针组件，其全部可释放地连接以限定中心轴向孔，其中被动阀密封组件包含阀密封件，其阻止气体穿过套管针组件进入大气当没有插入仪器而是打开以允许仪器插入时，仪器密封组件包含仪器减速器密封件，当器械通过阀密封件插入时，该密封件防止气体通过套管针组件进入大气中。被动阀密封组件和仪器密封组件优选地由塑料构成，以便是一次性的，而套管优选地由可灭菌材料组成以使得能够重复使用。

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