专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

41. 发明授权

US5418168A Biologically pure culture of the microorganism, streptomyces cyaneogriseus subspecies noncyanogenus, or a mutant thereof 失效
标题翻译：微生物的生物学纯培养物，非花青素链霉菌亚种，或其突变体
公开(公告)号：US5418168A
公开(公告)日：1995-05-23
申请号：US927581
申请日：1992-08-10
申请人： Guy T. Carter , Margaret J. Torrey , Michael Greenstein
发明人： Guy T. Carter , Margaret J. Torrey , Michael Greenstein
IPC分类号： A01N63/02 , C07H19/01 , C12P1/06 , C12N1/20 , C12P17/18
CPC分类号： C07H19/01 , A01N63/02 , C12P1/06 , Y10S435/88 , Y10S435/886
摘要： This invention relates to new agents designated LL-F28249.alpha., LL-F28249.beta., LL-F28249.gamma., LL-F28249.delta., LL-F28249.epsilon., LL-F28249.zeta., LL-F28249.eta., LL-F28249.theta., LL-F28249.iota., LL-F28249.kappa., LL-F28249.lambda., LL-F28249.mu., LL-F28249.nu., and LL-F28249.omega., to their production by fermentation, to methods for their recovery and concentration from crude solutions, to processes for their purification and to pharmaceutically and pharmacologically-acceptable salts thereof. The present invention includes within its scope the biologically pure culture which produces there agents, derived from a newly-discovered and previously uncultured microorganism, Streptomyces cyaneogriseus subsp. noncyanogenus, NRRL 15773.
摘要翻译：本发明涉及称为LL-F28249α，LL-F28249β，LL-F28249γ，LL-F28249Δ，LL-F28249ε，LL-F28249zeta，LL-F28249 eta，LL-F28249θ，LL-F28249 iota，LL-F28249 kappa，LL-F28249λ，LL-F28249 mu，LL-F28249nu和LL-F28249 omega，通过发酵生产，其从粗溶液中回收和浓缩的方法，以及其纯化方法以及其药学上和药理上可接受的盐。本发明在其范围内包括衍生自新发现和先前未培养的微生物Streptomyces cyaneogriseus subsp。的生物纯培养物。非花青素，NRRL 15773。

42. 发明申请

US20110177562A1 Portable Preparation, Analysis, and Detection Apparatus for Nucleic Acid Processing 审中-公开
标题翻译：用于核酸加工的便携式制备，分析和检测装置
公开(公告)号：US20110177562A1
公开(公告)日：2011-07-21
申请号：US12973190
申请日：2010-12-20
申请人： Charles S. Vann , Michael Greenstein , Yuh-Min Chiang
发明人： Charles S. Vann , Michael Greenstein , Yuh-Min Chiang
IPC分类号： C12P19/34 , G01N27/447
CPC分类号： G01N27/447 , C12M47/06 , C12Q1/6806 , C12Q1/686
摘要： The present teachings comprise a device and method for lysing and/or purifying biological sample. The device can comprise a cartridge having a chamber containing a biological sample receiving region, a plurality of electrodes, and one or more sieving matrices. The electrodes can be configured to lyse the biological sample through the production of a pulsed electrical field. The electrodes can also be configured to heat lyse the biological sample. The electrodes can also be configured to electrophoretically move the biological sample through one or more sieving matrices. A portion of the sample can be isolated on a membrane. The portion of the sample isolated on the membrane can be amplified and detected. A portion of the sample can be isolated in a collection area present in the cartridge. The portion of the sample isolated in the collection area can be removed from the cartridge.
摘要翻译：本教导包括用于裂解和/或纯化生物样品的装置和方法。该装置可以包括具有包含生物样品接收区域，多个电极和一个或多个筛分基质的腔室的药筒。电极可以被配置成通过产生脉冲电场来裂解生物样品。电极也可以被配置为热裂解生物样品。电极还可以被配置成通过一个或多个筛分基质电泳移动生物样品。样品的一部分可以在膜上分离。可以扩增和检测在膜上分离的样品的部分。样品的一部分可以在存在于盒中的收集区域中分离。分离在收集区域中的样品的部分可以从盒中取出。

43. 发明申请

US20110070587A1 System For Genetic Surveillance and Analysis 审中-公开
标题翻译：遗传监测与分析系统
公开(公告)号：US20110070587A1
公开(公告)日：2011-03-24
申请号：US12868704
申请日：2010-08-25
申请人： Hans FUERNKRANZ , Chirag J. Patel , Michael Greenstein
发明人： Hans FUERNKRANZ , Chirag J. Patel , Michael Greenstein
IPC分类号： C12Q1/68 , C12M1/34 , C40B60/12 , G06F19/00
CPC分类号： G16B30/00 , G06F19/00 , G16B25/00 , G16B50/00 , G16H10/40 , G16H50/80 , Y02A90/22 , Y02A90/24 , Y02A90/26
摘要： A genetic surveillance system comprises a communications network and at least one reader-analyzer instrument. The reader-analyzer instrument has a communication interface to communicate over the network. The reader-analyzer instrument is adapted to perform genetic assay analysis of a sample obtained from a member of a population and to generate detection-related data based upon the analysis. The reader-analyzer instrument is adapted to associate qualifying information with the detection-related data and to communicate the associated qualifying information and detection-related data over the network.
摘要翻译：遗传监测系统包括通信网络和至少一个读取器分析仪器。读取器分析仪具有通过网络进行通信的通信接口。读取器分析仪适于对从群体成员获得的样品进行遗传测定分析，并且基于分析产生检测相关数据。读取器分析仪器适于将限定信息与检测相关数据相关联，并通过网络传送相关联的限定信息和检测相关数据。

44. 发明授权

US07666149B2 Cassette of lancet cartridges for sampling blood 有权
标题翻译：用于取样血液的柳叶刀墨盒盒
公开(公告)号：US07666149B2
公开(公告)日：2010-02-23
申请号：US10282927
申请日：2002-10-28
申请人： Tad Decatur Simons , Michael Greenstein , Dominique M. Freeman , Leslie Anne Leonard , David A. King , Paul Lum
发明人： Tad Decatur Simons , Michael Greenstein , Dominique M. Freeman , Leslie Anne Leonard , David A. King , Paul Lum
IPC分类号： A61B5/00 , B65D81/00
CPC分类号： A61B5/157 , A61B5/150022 , A61B5/150305 , A61B5/150358 , A61B5/150412 , A61B5/15113 , A61B5/15153 , A61B5/15159 , A61B5/15165 , A61B5/15174 , A61B2562/0295 , Y10S436/808
摘要： A cassette containing cartridges for sampling blood from a patient. The cassette includes a container for storing a plurality of cartridges and at least one cartridge in the container. The cartridge includes a cartridge case and a lancet. The lancet has a tip and is housed in the cartridge case. The lancet can be driven to extend the tip outside the cartridge case for lancing the skin of the patient to yield blood. The container has a compartment that contains at least one cartridge. A cartridge from the compartment can be loaded onto a glucometer that drives the lancet in the cartridge to lance the skin of a patient.
摘要翻译：包含用于从患者取血的药筒的药盒。盒式磁带包括用于存储多个盒的容器和容器中的至少一个盒。药筒包括药筒盒和刺血针。刺血针具有尖端并且容纳在盒壳体中。可以驱动柳叶刀将尖端延伸到药筒壳体外部，以便撕裂患者的皮肤以产生血液。容器具有包含至少一个盒的隔间。来自隔室的药筒可以被装载到驱动药筒中的刺血针的血糖仪上以刺穿患者的皮肤。

45. 发明授权

US07303727B1 Microfluidic sample delivery devices, systems, and methods 有权
标题翻译：微流体样品输送装置，系统和方法
公开(公告)号：US07303727B1
公开(公告)日：2007-12-04
申请号：US10369325
申请日：2003-02-19
申请人： Robert S. Dubrow , Michael Greenstein , Luc J. Bousse , Khushroo Gandhi
发明人： Robert S. Dubrow , Michael Greenstein , Luc J. Bousse , Khushroo Gandhi
IPC分类号： B01L3/02 , B32B5/02 , B32B27/04 , B32B27/12 , G01N15/06
CPC分类号： H01J49/167 , B01L3/0268 , B01L3/502715 , B01L3/565 , B01L2200/027 , B01L2200/12 , B01L2300/0816 , B01L2300/0838 , B01L2300/0864 , B01L2300/0867 , B01L2400/027 , B01L2400/0415 , B01L2400/0487 , G01N30/6095 , G01N30/84 , G01N35/1095 , G01N2030/847 , G01N2030/8488 , G01N2035/1039 , Y10T436/11 , Y10T436/118339 , Y10T436/119163 , Y10T436/25 , Y10T436/2575
摘要： Methods and apparatus for delivering fluidic materials to sample destinations, including mass spectrometers for analysis are provided. In preferred embodiments, sample aliquots are electrosprayed from tapered spray tips of capillary elements into the orifices of mass spectrometric inlet systems. In certain embodiments, fluidic samples are orthogonally sprayed from capillary elements or other fluid conduits, whereas in other embodiments samples are sprayed after devices are rotated or otherwise translocated from sample sources to sample destinations. In still other embodiments, samples are sprayed from flexed or deflected capillary elements at selected sample destinations.
摘要翻译：提供了将流体材料输送到样品目的地的方法和设备，包括用于分析的质谱仪。在优选的实施方案中，将样品等分试样从毛细管元件的锥形喷嘴电喷雾到质谱入口系统的孔中。在某些实施方案中，流体样品从毛细管元件或其他流体导管正交喷射，而在其它实施方案中，在将装置旋转或以其他方式从样品源转移到样品目的地之后，将样品喷雾。在其它实施例中，样品在选定的样品目的地从挠曲或偏转的毛细管元件喷射。

46. 发明授权

US07036667B2 Container providing a controlled hydrated environment 失效
标题翻译：集装箱提供受控的水合环境
公开(公告)号：US07036667B2
公开(公告)日：2006-05-02
申请号：US10837707
申请日：2004-05-04
申请人： Michael Greenstein , Colin Kennedy , Huan Phan , Stephan Bianchi , Jonathan Reed Harris , Daren Walter Hebold , Robert Andrew Howard , Andrew Leonard Zee
发明人： Michael Greenstein , Colin Kennedy , Huan Phan , Stephan Bianchi , Jonathan Reed Harris , Daren Walter Hebold , Robert Andrew Howard , Andrew Leonard Zee
IPC分类号： B65D85/00
CPC分类号： B01L9/527 , B01L2200/025 , B01L2200/0689 , B01L2200/185 , B01L2300/041 , B65D85/70
摘要： A container is provided for shipping and storing a pre-wetted and pre-conditioned microfluidic “sipper” chip. The container contains both dry compartments and wet compartments. A base contains a fluid-filled reservoir configured to house the capillaries. The opening of the reservoir is sealed with an O-ring. The plastic mount of the chip rests on the base in a dry compartment. The upper surface of the chip contains several wells containing fluid. A gasket is provided with plugs configured to be disposed within and seal the wells. Alternatively, the wells are first sealed with a foil film adhered to the well openings with an adhesive and a gasket is disposed between the foil and a cover, which is removably attached to the base. When the cover is closed, the gasket and O-ring seal the wet compartments to prevent leakage and to slow evaporation.
摘要翻译：提供了用于运输和存储预润湿和预调节微流控“吸嘴”芯片的容器。容器包含干燥隔室和湿隔间。基座包含配置成容纳毛细管的流体填充的储存器。储罐的开口用O形圈密封。芯片的塑料安装座位于干燥隔间的底座上。芯片的上表面包含几个含有流体的孔。垫圈设置有被配置为设置在井中并密封井的塞子。或者，孔首先用粘合剂粘附到井口上的箔膜密封，并且垫片设置在箔和盖之间，盖可拆卸地附接到基座。当盖子关闭时，垫圈和O形圈密封湿隔间，以防止泄漏并减缓蒸发。

47. 发明授权

US06966880B2 Universal diagnostic platform 有权
标题翻译：通用诊断平台
公开(公告)号：US06966880B2
公开(公告)日：2005-11-22
申请号：US09981483
申请日：2001-10-16
申请人： Dirk Boecker , Rick Pittaro , Michael Greenstein , Michael C. Higgins , Dominique M. Freeman
发明人： Dirk Boecker , Rick Pittaro , Michael Greenstein , Michael C. Higgins , Dominique M. Freeman
IPC分类号： A61B5/00 , A61B5/15
CPC分类号： A61M5/142 , A61B5/0002 , A61B5/145 , A61B5/14532 , A61B5/150022 , A61B5/150221 , A61B5/150412 , A61B5/150503 , A61B5/150755 , A61B5/150854 , A61B5/15113 , A61B5/15117 , A61B5/15121 , A61B5/15123 , A61B5/1519 , A61M2205/3576 , G06F19/00 , H04L67/025 , H04L67/1097 , H04L67/12 , Y10S128/903
摘要： A portable medical analyzer comprising a sampling module with a sample port for receiving body fluid, an assay sensor module for analysis of the body fluid, an analytical detector module with detection of information from the assay, and a communications module for transferring the information to a remote location via a wired or wireless network.
摘要翻译：一种便携式医学分析仪，包括具有用于接收体液的采样端口的采样模块，用于分析体液的测定传感器模块，具有来自测定的信息检测的分析检测器模块，以及用于将信息传送到通过有线或无线网络进行远程位置。

48. 发明授权

US6139562A Apparatus and method for incising 失效
标题翻译：切割装置及方法
公开(公告)号：US6139562A
公开(公告)日：2000-10-31
申请号：US50748
申请日：1998-03-30
申请人： Ganapati R. Mauze , Michael Greenstein , Edward D. Verdonk , Paul Lum
发明人： Ganapati R. Mauze , Michael Greenstein , Edward D. Verdonk , Paul Lum
IPC分类号： A61B5/151 , A61B5/15 , A61B10/00 , A61B10/02 , A61B17/32 , A61B17/34 , A61B17/14
CPC分类号： A61B10/0233 , A61B10/0266 , A61B17/32053 , A61B17/32093 , A61B5/14514 , A61B5/150022 , A61B5/150137 , A61B5/15016 , A61B5/150396 , A61B5/150419 , A61B5/150427 , A61B5/150511 , A61B5/15121 , A61B5/15142 , A61B17/32002 , A61B17/3476
摘要： A multi-shaft apparatus for incising a substrate of soft resilient material such as a body tissue. The incising apparatus includes two or more incision shafts each having a distal edge. The shafts are not affixed to each other and are allowed to slide against each other to drive the distal edges alternately against the substrate to incise the substrate. In the case of incising a body tissue, such alternate motion would result in less pain to the patient than a puncture resulting from a sharp jab by a sharp shaft of similar size to the shafts.
摘要翻译：一种用于切割诸如身体组织的软弹性材料的基底的多轴装置。切割装置包括两个或更多个切口轴，每个切口具有远端边缘。轴彼此不固定并且允许彼此滑动以将远端边缘交替地驱动抵靠基板以切割基板。在切割身体组织的情况下，这种交替运动将导致比通过与轴相似尺寸的尖锐的尖锐刺戳导致的穿刺更少的疼痛。

49. 发明授权

US6036924A Cassette of lancet cartridges for sampling blood 失效
标题翻译：用于取样血液的柳叶刀墨盒盒
公开(公告)号：US6036924A
公开(公告)日：2000-03-14
申请号：US985299
申请日：1997-12-04
申请人： Tad Decatur Simons , Michael Greenstein , Dominique Freeman , Leslie Anne Leonard , David A. King , Paul Lum
发明人： Tad Decatur Simons , Michael Greenstein , Dominique Freeman , Leslie Anne Leonard , David A. King , Paul Lum
IPC分类号： A61B5/15 , A61B17/32
CPC分类号： A61B5/157 , A61B5/150022 , A61B5/150305 , A61B5/150358 , A61B5/150412 , A61B5/15113 , A61B5/15153 , A61B5/15174 , A61B2562/0295 , A61B5/15159 , A61B5/15165 , Y10S436/808
摘要： A cassette containing cartridges for sampling blood from a patient. The cassette includes a container for storing a plurality of cartridges and at least one cartridge in the container. The cartridge includes a cartridge case and a lancet. The lancet has a tip and is housed in the cartridge case. The lancet can be driven to extend the tip outside the cartridge case for lancing the skin of the patient to yield blood. The container has a compartment that contains at least one cartridge. A cartridge from the compartment can be loaded onto a glucometer that drives the lancet in the cartridge to lance the skin of a patient.
摘要翻译：包含用于从患者取血的药筒的药盒。盒式磁带包括用于存储多个盒的容器和容器中的至少一个盒。药筒包括药筒盒和刺血针。刺血针具有尖端并且容纳在盒壳体中。可以驱动柳叶刀将尖端延伸到药筒壳体外部，以便撕裂患者的皮肤以产生血液。容器具有包含至少一个盒的隔间。来自隔室的药筒可以被装载到驱动药筒中的刺血针的血糖仪上以刺激患者的皮肤。

50. 发明授权

US5938679A Apparatus and method for minimally invasive blood sampling 失效
标题翻译：微创血液取样装置及方法
公开(公告)号：US5938679A
公开(公告)日：1999-08-17
申请号：US949727
申请日：1997-10-14
申请人： Dominique Freeman , Paul Lum , David King , Tad Simons , Michael Greenstein
发明人： Dominique Freeman , Paul Lum , David King , Tad Simons , Michael Greenstein
IPC分类号： A61B5/15 , A61B17/14
CPC分类号： A61B5/15142 , A61B5/150022 , A61B5/150099 , A61B5/150419 , A61B5/150427 , A61B5/15113 , A61B5/15128
摘要： A blood sampling device for penetrating skin to obtain a blood sample is disclosed. The blood sampling device has a blade structure that can be extended from a housing to pierce the skin and then retracted. The blade structure has at least two blades each including a cutting edge. The blades abut one another to form a rigid joint from which the blades extend. The blades each have a distal portion in which the distance from the rigid joint to the cutting edge decreases towards and terminates at a sharp point at a distal end. Each blade generally forms an angle less than 180 degrees with at least one neighboring blade. This structure decreases the tendency of the blade structure to flex as the distal end of the blade structure penetrates the skin to yield blood.
摘要翻译：公开了一种用于穿透皮肤以获得血液样本的血液采样装置。采血装置具有可从壳体延伸以刺穿皮肤然后缩回的刀片结构。叶片结构具有至少两个叶片，每个叶片包括切割边缘。刀片彼此邻接以形成刀片延伸的刚性接头。叶片各自具有远端部分，其中从刚性接头到切割刃的距离在远端处朝向并终止于尖端的尖端处。每个刀片通常与至少一个相邻刀片形成小于180度的角度。当叶片结构的远端穿透皮肤以产生血液时，这种结构降低了叶片结构的挠曲倾向。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式