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    • 54. 发明申请
    • Nasal irrigation solutions and methods of using same
    • 鼻灌洗方法及其使用方法
    • US20040091556A1
    • 2004-05-13
    • US10630166
    • 2003-07-30
    • Rajmani TigunaitJames L. Miles
    • A01N065/00
    • A61K45/06A61K31/4741A61K36/28A61K36/29A61K36/71A61K36/718A61K36/752A61K36/756A61K36/87A61K2300/00
    • A nasal irrigation solution comprising is disclosed comprising water and hydrastine extracted from one or more plants. Another solution comprises water and berberine extracted from one or more plants. These solutions are provided from an extract of goldenseal plant. Solutions are also disclosed having canadine, canadaline, and hydrastidine, all extracted from the goldenseal plant. More general solutions are disclosed including alkaloids extracted from one or more plants. The alkaloids are selected from one or more of the group consisting of: berberine, oxyberberine, berbamine, palmatine, magnoflorine, phellodendrine, jateorrhizine, candicine, menisperine, coptisine, worenine, columbamine, epiberberine, hydrastine, canadine, canadaline, hydrastidine, oxycyanthine, berberrubine, and isotetrandine. Alkaloids are provided from plant from the group consisting of: Oregon grape root, yellow root, phellodendron bark, coptis rhizome, barberry root, and Indian barberry root bark. Other constituents may include extract of grapefruit seed, vegetable glycerine, salt, and water soluble zinc. A method for using these solutions is disclosed which includes flowing the solution through desired portions of nasal cavities.
    • 公开了包含从一种或多种植物提取的水和hydrastine的鼻灌洗溶液。 另一种解决方案包括从一个或多个植物提取的水和小檗碱。 这些溶液是由金缕梅植物提取物提供的。 还公开了解决方案,其具有从金缕梅植物中提取的加拿大,加拿丹和hydrastidine。 公开了更一般的解决方案,包括从一个或多个植物提取的生物碱。 生物碱选自以下组中的一种或多种:小檗碱,oxyberberine,berbamine,巴马汀,magnoflorine,黄柏,苦参,盐酸,半夏替宁,黄连碱,枸橼酸,哥伦巴胺,表皮质激素,hydrastine,加纳丹,canadaline,hydrastidine, 柏柏林和异君子碱。 生物碱由植物提供,由以下组成:俄勒冈葡萄根,黄根,黄柏树皮,黄连根茎,番茄根和印度番茄根皮。 其他成分可以包括葡萄柚籽,植物甘油,盐和水溶性锌的提取物。 公开了一种使用这些溶液的方法,其包括使溶液流过鼻腔的所需部分。
    • 56. 发明授权
    • Pharmaceutical preparation for the treatment of topical wounds and ulcers
    • 用于治疗局部创面和溃疡的药物制剂
    • US06555118B1
    • 2003-04-29
    • US09681207
    • 2001-02-22
    • Sarfaraz K Niazi
    • Sarfaraz K Niazi
    • A61K3578
    • A61Q19/00A61K8/63A61K8/922A61K8/97A61K36/31A61K36/33A61K36/48A61K36/539A61K36/756A61K2800/75A61L26/0057A61L26/0066A61L2300/222A61L2300/30A61L2300/412A61Q17/00A61Q19/001Y10S424/13Y10S514/844Y10S514/944Y10S514/945A61K2300/00
    • A pharmaceutical preparation for the treatment of wounds and ulcers in humans and animals and a method of preparation of the same are provided here. The composition consists of an alcoholic extract of Huangqin, Huanglian, Huangbai, Opuntia, Dilong, and &bgr;-sitosterol (from Soybean extract), in a vegetable oil-wax base, from where the alcohol is essentially removed by evaporation. The composition is used as a topical ointment for the treatment of wounds in its preferred embodiment. Wounds, in particular those occurring in the skin as second and third degree burns, stasis ulcers, trophic lesions, such as decubitus ulcers, diabetic ulcers, surgical wounds, severe cuts, diaper rash, cracked nipples and abrasions which are commonly resistant to the natural healing process, may be treated with this composition. The application of this combination to wounds greatly accelerates the rate of healing and reduces scarring as the mechanism of action proposed here involves regeneration of skin through stimulation of stem cells that allows healing without substantial scar formation.
    • 本发明提供了用于治疗人和动物中的伤口和溃疡的药物制剂及其制备方法。 该组合物由植物油蜡基中的黄琴,黄连,黄柏,仙人掌,迪龙和β-谷甾醇的醇提物组成,其中醇通过蒸发基本上被除去。 该组合物在其优选实施方案中用作治疗伤口的局部软膏。 伤口,特别是皮肤中发生的第二和第三度烧伤,溃疡,营养性损伤,如褥疮性溃疡,糖尿病性溃疡,手术伤口,严重切口,尿布疹,裂纹乳头和擦伤,这些伤口通常对天然抗性 治疗过程中,可以用这种组合物治疗。 这种组合对伤口的应用极大地加快了愈合速度并减少了瘢痕形成,因为这里提出的作用机制涉及通过刺激干细胞来再生皮肤,其允许在没有实质性瘢痕形​​成的情况下愈合。
    • 59. 发明授权
    • Externally-applied medicine for curing black foot disease
    • 外用药治疗黑脚病
    • US6077512A
    • 2000-06-20
    • US497169
    • 1995-06-30
    • Ren-Rong Chen
    • Ren-Rong Chen
    • A61K31/045A61K33/22A61K36/324A61K36/328A61K36/48A61K36/61A61K36/756A61K36/8884A61K36/8888A61K36/898A61K35/78
    • A61K36/328A61K31/045A61K33/22A61K36/324A61K36/48A61K36/61A61K36/756A61K36/8884A61K36/8888A61K36/898Y10S514/887
    • An externally-applied medicine for curing black foot disease comprising a basis part consisting of equal amount of ground, powdered, and mixed clove, frankincense, myrrha, rhizama arisaematis, pinellia, monkshood (root) or kusnezoff monkshood (root), and tuber of bamboo-leaved orchid, and an adjuvant part consisting of equal amount of round, powdered, and mixed borneol, powdered soy bean, borax, coptis root and/or phellodendron amureuse, and sepia aculeata. The medicine is used in such a manner that the powdered basis part is mixed and stirred with tea water until it becomes plaster-like, and the adjuvant part is scattered in dry form onto the wound or swollen area caused by the black foot disease before the plaster-like basis part is applied to the wound or swollen area about 0.5 cm in thickness. The wound is then bandaged and the medicine is renewed once to twice a day until fresh flesh appears in the wound. Thereafter, the medicine is continuously applied but in a dry form until the wound is completely healed.
    • 一种用于治疗黑脚病的外用药物,包括由等量的地面,粉末和混合丁香,乳香,没药,根瘤菌,针茅,僧侣(根)或kusnezoff僧侣(根)组成的基础部分和块茎 竹叶兰,以及由等量的圆形,粉状和混合的冰片,粉状大豆,硼砂,黄连根和/或黄柏香草和乌贼属组成的辅助部分。 该药物的使用方法是将粉末状基础部分与茶水混合搅拌直至变成石膏状,并且佐剂部分以干燥形式散布到由黑脚病引起的伤口或肿胀部位 石膏状基础部位适用于约0.5cm厚的伤口或肿胀区域。 伤口然后被包扎,药物每天更新一次,直到新鲜的肉出现在伤口中。 此后,药物被连续施用,但以干燥形式直到伤口完全愈合。