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1. 发明授权

US09782448B2 Methods and compositions for treating skin 有权
公开(公告)号：US09782448B2
公开(公告)日：2017-10-10
申请号：US13957647
申请日：2013-08-02
申请人： Donald F. Collins , Daniel H. Maes , Neelam Muizzuddin
发明人： Donald F. Collins , Daniel H. Maes , Neelam Muizzuddin
IPC分类号： A61K36/752 , A61K8/34 , A61K8/49 , A61K8/63 , A61K8/97 , A61Q19/00 , A61K31/05 , A61K31/19 , A61K35/614 , A61K36/02 , A61K36/28 , A61K36/38 , A61K36/575 , A61K8/9706
CPC分类号： A61K36/752 , A61K8/347 , A61K8/498 , A61K8/63 , A61K8/97 , A61K8/9706 , A61K31/05 , A61K31/19 , A61K35/614 , A61K36/02 , A61K36/28 , A61K36/38 , A61K36/575 , A61K2800/75 , A61Q19/008
摘要： A method for treating intact irritated or inflamed skin with a composition comprising at least one Histamine Receptor pathway inhibitor; at least one Lipoxygenase pathway inhibitor; at least one Cyclooxygenase pathway inhibitor and at least one Chemotaxis pathway inhibitor.

2. 发明申请

US20150374778A1 Pharmaceutical composition for treating cancers and preparation method therefor 审中-公开
标题翻译：用于治疗癌症的药物组合物及其制备方法
公开(公告)号：US20150374778A1
公开(公告)日：2015-12-31
申请号：US14846786
申请日：2015-09-06
申请人： Mingchun Xiao
发明人： Mingchun Xiao
IPC分类号： A61K36/9068 , A61K36/8988 , A61K36/07 , A61K36/752 , A61K36/284 , A61K36/484 , A61K36/575 , A61K36/236 , A61K36/232 , A61K36/237 , A61K36/268 , A61K36/85 , A61K36/185 , A61K36/46 , A61K36/21 , A61K36/515 , A61K36/54 , A61K36/258 , A61K36/65 , A61K36/804 , A61K36/481 , A61K36/714 , A61K36/12 , A61K36/884 , A61K36/8945 , A61K36/882 , A61K36/9062 , A61K36/734 , A61K36/8888
CPC分类号： A61K36/9068 , A23F3/163 , A61K36/07 , A61K36/076 , A61K36/12 , A61K36/185 , A61K36/21 , A61K36/232 , A61K36/233 , A61K36/236 , A61K36/237 , A61K36/258 , A61K36/268 , A61K36/284 , A61K36/46 , A61K36/48 , A61K36/481 , A61K36/482 , A61K36/484 , A61K36/515 , A61K36/53 , A61K36/532 , A61K36/535 , A61K36/538 , A61K36/539 , A61K36/54 , A61K36/575 , A61K36/65 , A61K36/66 , A61K36/68 , A61K36/71 , A61K36/714 , A61K36/734 , A61K36/752 , A61K36/804 , A61K36/85 , A61K36/88 , A61K36/882 , A61K36/884 , A61K36/888 , A61K36/8884 , A61K36/8888 , A61K36/8905 , A61K36/8945 , A61K36/8988 , A61K36/8998 , A61K36/906 , A61K36/9062 , A61K36/9064 , A61K36/9066 , A61K2300/00
摘要： A pharmaceutical composition for treating cancers and preparation method thereof. Said composition for treating cancers contains Chinese medicinal materials including Rhizoma Pinelliae, Rhizoma Arisaematis, Rhizoma Gastrodiae etc., and said preparation method is in accordance with a conventional Chinese medicinal preparation method, manufacturing said composition to form any one of the ordinary oral preparations.
摘要翻译：一种治疗癌症的药物组合物及其制备方法。所述治疗癌症的组合物含有中药材，包括苦参，苦参，天麻等，所述制备方法按照常规的中药制备方法，制备所述组合物以形成任何一种普通口服制剂。

3. 发明申请

US20100323042A1 Methods And Compositions For Treating Skin 有权
标题翻译：治疗皮肤的方法和组合
公开(公告)号：US20100323042A1
公开(公告)日：2010-12-23
申请号：US12743500
申请日：2008-07-07
申请人： Donald F. Collins , Daniel H. Maes , Neelam Muizzuddin
发明人： Donald F. Collins , Daniel H. Maes , Neelam Muizzuddin
IPC分类号： A61K36/736 , A61K36/899 , A61P29/00
CPC分类号： A61K36/752 , A61K8/347 , A61K8/498 , A61K8/63 , A61K8/97 , A61K8/9706 , A61K31/05 , A61K31/19 , A61K35/614 , A61K36/02 , A61K36/28 , A61K36/38 , A61K36/575 , A61K2800/75 , A61Q19/008
摘要： A method for formulating products to normalize skin or treat irritated or inflamed skin, a method for normalizing skin or treating irritated or inflamed skin for improvement, and compositions therefor.
摘要翻译：用于配制产品以使皮肤正常化或治疗刺激性或发炎的皮肤的方法，使皮肤正常化或治疗刺激性或发炎皮肤以改善的方法及其组合物。

4. 发明授权

US07740831B2 Compositions for potentiating glutathione 失效
标题翻译：用于增强谷胱甘肽的组合物
公开(公告)号：US07740831B2
公开(公告)日：2010-06-22
申请号：US10492077
申请日：2002-09-11
申请人： Tomohiro Chiba , Takashi Naito , Shioji Ishiwatari
发明人： Tomohiro Chiba , Takashi Naito , Shioji Ishiwatari
IPC分类号： A61Q5/08 , A61Q9/00 , A01N65/00 , A61K36/68 , A61K31/70 , A61K31/05 , A61K36/736 , A61K36/28
CPC分类号： A61Q19/02 , A61K8/347 , A61K8/602 , A61K8/922 , A61K8/97 , A61K31/065 , A61K31/7028 , A61K36/05 , A61K36/21 , A61K36/28 , A61K36/42 , A61K36/49 , A61K36/53 , A61K36/575 , A61K36/63 , A61K36/634 , A61K36/638 , A61K36/64 , A61K36/68 , A61K36/736 , A61K36/80 , A61K36/804 , A61K36/85 , A61K2800/522 , A61Q17/04 , A61Q19/08
摘要： A composition for potentiating glutathione, which contains at least one member selected from the group consisting of 2-(3,4-dihydroxyphenyl)ethanol or a glycoside thereof, a plant containing 2-(3,4-dihydroxyphenyl)ethanol or a glycoside thereof, an extract of said plant, a hydrolysate of said plant, and a hydrolysate of the extract of said plant (excluding Olea europaea and an extract thereof), and which further contains at least one member selected from among an S-containing compound that is a supply source of cysteine, a protein that contains cysteine and/or cystine, a yeast that contains cysteine and/or cystine, and a vitamin.
摘要翻译：一种用于增强谷胱甘肽的组合物，其含有选自2-（3,4-二羟基苯基）乙醇或其糖苷中的至少一种，含有2-（3,4-二羟基苯基）乙醇或其糖苷的植物，所述植物的提取物，所述植物的水解产物和所述植物提取物的水解产物（不包括欧莱雅及其提取物），并且还含有至少一种选自以下的含S化合物中的至少一种：半胱氨酸的供应源，含有半胱氨酸和/或胱氨酸的蛋白质，含有半胱氨酸和/或胱氨酸的酵母和维生素。

5. 发明申请

US20100055218A1 NOVEL COMPOSITIONS 审中-公开
标题翻译：新组合
公开(公告)号：US20100055218A1
公开(公告)日：2010-03-04
申请号：US12373617
申请日：2007-07-12
申请人： Daniel Raederstorff , Joseph Schwager , Karin Wertz
发明人： Daniel Raederstorff , Joseph Schwager , Karin Wertz
IPC分类号： A61K36/73
CPC分类号： A61K36/484 , A23L33/105 , A23V2002/00 , A61K31/635 , A61K36/185 , A61K36/23 , A61K36/575 , A61K36/738 , A61K36/76 , A61K36/77 , A61K45/06 , A61K2300/00 , A23V2200/324 , A23V2250/21
摘要： The present invention relates to novel compositions comprising rosehip and at least one additional component e.g. selected from ligustilide, oleuropein (I), oleuropein aglycone (II), hydroxytyrosol, genistein, magnolol, honokiol, magnolia bark extract, cashew fruit extract and Glycyrrhiza foetida as well as to the use of these compositions as a medicament, in particular as a medicament for the treatment, co-treatment or prevention of inflammatory disorders.
摘要翻译：本发明涉及包含玫瑰果和至少一种另外的组分的新型组合物，例如选自ligustilide，oleuropein（I），oleuropein糖苷配基（II），羟基酪醇，染料木素，厚朴酚，厚朴酚，木兰树皮提取物，腰果提取物和甘草，以及这些组合物作为药物的用途，特别是作为用于治疗，共同治疗或预防炎症性疾病的药物。

6. 发明申请

US20100003351A1 COMPOSITIONS COMPRISING RHODIOLA ROSEA AND METHODS OF USE THEREOF 审中-公开
标题翻译：包含RHODIOLA ROSEA的组合物及其使用方法
公开(公告)号：US20100003351A1
公开(公告)日：2010-01-07
申请号：US12166825
申请日：2008-07-02
申请人： Russell M. JAFFE
发明人： Russell M. JAFFE
IPC分类号： A61K36/00 , A61K31/70
CPC分类号： A61K31/7028 , A61K36/41 , A61K36/575 , A61K36/756 , A61K2300/00
摘要： The present invention relates to compositions and kits comprising an extract of Rhodiola rosea, and one or more extracts selected from the group consisting of Magnolia officinalis and Phellodendron amurense. The present invention also relates to methods of treating a disease or condition associated with adrenal fatigue and/or insulin resistance by administering these compositions.
摘要翻译：本发明涉及包含红景天提取物的组合物和试剂盒，以及一种或多种提取物，其选自木兰木兰（Magnolia officinalis）和黄柏（Phellodendron amurense）。本发明还涉及通过施用这些组合物治疗与肾上腺疲劳和/或胰岛素抵抗相关的疾病或病症的方法。

7. 发明申请

US20090087407A1 METHODS FOR THE TREATMENT OF SCLERODERMA USING 1-OXO-2-(2,6-DIOXOPIPERIDIN-3-YL)-4-METHYLISOINDOLINE 审中-公开
标题翻译：使用1-氧代-2-（2,6-二氧代吡啶-3-基）-4-甲基异吲哚啉处理苦参碱的方法
公开(公告)号：US20090087407A1
公开(公告)日：2009-04-02
申请号：US12249350
申请日：2008-10-10
申请人： Jerome B. Zeldis , Robert J. Hariri
发明人： Jerome B. Zeldis , Robert J. Hariri
IPC分类号： A61K31/454 , A61K38/21 , A61P17/00
CPC分类号： A61K31/19 , A61K31/59 , A61K36/28 , A61K36/575 , A61K2300/00
摘要： Methods of treating, preventing, correcting and/or managing skin diseases or disorders characterized by overgrowths of the epidermis, keratoses, scleroderma, cutaneous vasculitis, acne or wrinkles are disclosed. Specific embodiments encompass the administration of an immunomodulatory compound, or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate, or prodrug thereof, alone or in combination with a second active agent. Specific second active ingredients are capable of affecting or inhibiting cell growth or proliferation, removing or improving acne scars, or reducing or correcting wrinkle lines. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.
摘要翻译：公开了治疗，预防，矫正和/或治疗以表皮过度生长，角化病，硬皮病，皮肤血管炎，痤疮或皱纹为特征的皮肤疾病或病症的方法。具体实施方案包括单独或与第二活性剂组合施用免疫调节化合物或其药学上可接受的盐，溶剂合物，水合物，立体异构体，包合物或前药。特定的第二活性成分能够影响或抑制细胞生长或增殖，去除或改善痤疮疤痕，或减少或纠正皱纹线。还公开了适用于本发明方法的药物组合物，单一单位剂型和试剂盒。

8. 发明申请

US20070160687A1 Composition for prevention and treatment of diabetic complication 审中-公开
标题翻译：预防和治疗糖尿病并发症的组合物
公开(公告)号：US20070160687A1
公开(公告)日：2007-07-12
申请号：US10588561
申请日：2004-12-31
申请人： Jin Kim , Sang Lee , Yin Mi Lee
发明人： Jin Kim , Sang Lee , Yin Mi Lee
IPC分类号： A61K36/575 , A61K36/47 , A61K36/48
CPC分类号： A61K36/575 , A23L33/105 , A61K36/47 , A61K36/484 , A61K36/488 , A61K2300/00
摘要： The present invention relates to a composition for the prevention and treatment of diabetic complications, which contains an extract obtained by: crushing and drying any one selected from Euphorbiae radix, gingered Magnolia bark, parched Puerariae radix and Glycyrrhizae radix; extracting the dried herbal material with alcohol or aqueous alcohol solution: filtering the extract; and concentrating the filtrate under reduced pressure. Alternatively, the composition contains a mixture of extracts from Euphorbiae radix, gingered Magnolia bark, parched Puerariae radix and Glycyrrhizae radix, the amount of each of the herbal extracts being 5-85% by weight based on 100% by weight of the herbal extract mixture. Alternatively, the composition contains magnolol obtained by: extracting Magnolia bark with aqueous 80% ethanol solution at ambient temperature for 24 hours; systematically separating the extract in the order of normal-hexane, ethyl acetate and normal-butanol; selecting the normal-hexane layer and separating the selected layer into pre-fractions by normal silica gel chromatography; comparing the pre-fractions with the standard form magnolol on TLC to determine a magnolol-enriched fraction; and separating magnolol from the magnolol-enriched fraction by silica gel column chromatography.
摘要翻译：本发明涉及一种预防和治疗糖尿病并发症的组合物，其含有通过以下方法获得的提取物：将来自大戟，，ered的木兰树皮，茯苓和甘草的任何一种粉碎和干燥; 用酒精或醇水溶液提取干草本材料：过滤提取物; 并在减压下浓缩滤液。或者，组合物含有来自大戟根，ered ered的木兰皮，灼热葛根和甘草的提取物的混合物，基于100重量％的草药提取物混合物，每个草药提取物的量为5-85重量％。或者，组合物含有通过以下方式获得的厚朴酚：用80％乙醇水溶液在室温下提取木兰树皮24小时; 以正己烷，乙酸乙酯和正丁醇的顺序系统分离提取物; 选择正己烷层，并通过常规硅胶色谱法将选择的层分离成预级分; 在TLC上比较预分数与标准形式的厚朴酚，以测定富含木酚的部分; 并通过硅胶柱色谱从厚朴酚组分中分离厚朴酚。

9. 发明申请

US20060141075A1 Methods and compositions for weight management and mood enhancement 审中-公开
公开(公告)号：US20060141075A1
公开(公告)日：2006-06-29
申请号：US11360312
申请日：2006-02-23
申请人： Shawn Talbott
发明人： Shawn Talbott
IPC分类号： A61K36/82 , A61K36/752 , A61K31/522 , A61K31/56 , A61K33/26 , A61K36/575
CPC分类号： A61K31/375 , A61K31/56 , A61K33/06 , A61K33/24 , A61K36/00 , A61K36/185 , A61K36/575 , A61K36/752 , A61K36/82 , A61K45/06 , A61K2300/00
摘要： The present invention provides nutritional supplement compositions and processes for treatment using nutritional supplements that assist in weight management. One aspect of the invention comprises the inclusion in a single supplement constituent(s) that assist in reduction of a subject's cortisol level, thermogenic constituent(s), and constituent(s) that assist in stabilizing blood sugar levels.

10. 发明申请

US20060140885A1 Method of reducing oral tissue inflammation using magnolia extract 审中-公开
标题翻译：使用木兰提取物减少口腔组织炎症的方法
公开(公告)号：US20060140885A1
公开(公告)日：2006-06-29
申请号：US11285809
申请日：2005-11-23
申请人： Abdul Gaffar , Dale Scherl , Susan Herles
发明人： Abdul Gaffar , Dale Scherl , Susan Herles
IPC分类号： A61K8/97 , A61K36/575
CPC分类号： A61K45/06 , A61K36/575 , A61K2300/00
摘要： A method for treating a mammal having oral tissue inflammation is provided, where the inflamed oral tissue is contacted with a safe, efficacious, non-irritating oral composition having an anti-inflammatory agent comprising a magnolia extract. The magnolia anti-inflammatory active ingredient reduces one or more mediators of inflammation and reduces inflammation in oral tissue. The oral composition can be in the form of a mouth rinse; dentifrice, including toothpaste, gels, powders, lozenges; medicament gel; animal products; and the like.
摘要翻译：提供了一种用于治疗具有口腔组织炎症的哺乳动物的方法，其中发炎口腔组织与具有包含木兰提取物的抗炎剂的安全有效的无刺激性口服组合物接触。木兰消炎活性成分减少一种或多种炎症介质并减少口腔组织中的炎症。口服组合物可以是口腔冲洗的形式; 牙膏，包括牙膏，凝胶，粉末，锭剂; 药物凝胶; 动物产品; 等等。

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