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1. 发明公开

KR20100033435A MEDICAL DEVICE 有权
标题翻译：医疗设备
公开(公告)号：KR20100033435A
公开(公告)日：2010-03-29
申请号：KR20107003719
申请日：2009-03-02
申请人： ARKRAY INC
发明人： KUBO MASAYUKI
IPC分类号： A61B5/145 , A61B5/00 , G01N27/28 , G09F3/02
CPC分类号： A61B5/14532 , A61B5/1495 , A61B2562/08 , G01N33/48785
摘要： Provided is a medical device (1) which measures a state of a biological body. The medical device (1) includes: a main body (2) containing a measurement device inside; and a sheet member (3). One side of the sheet member (3) displays information (4) concerning a user and the other side is attached to the external surface of the main body (2). The sheet member (3) has a sheet-shaped base (6), a protection layer (5) formed on one side (6a) of the base (6), and an adhesive layer (7) formed on the other side (6b) of the base (6). Here, the protection layer (5) is preferably formed from a translucent material and the one side (6a) of the base (6) preferably displays information (4) on the user.

2. 发明申请

WO2010106781A1 METHOD OF CONTINUOUSLY MEASURING SUBSTRATE CONCENTRATION 审中-公开
标题翻译：连续测量基板浓度的方法
公开(公告)号：WO2010106781A1
公开(公告)日：2010-09-23
申请号：PCT/JP2010/001834
申请日：2010-03-15
申请人： ARKRAY, Inc. , KATSUKI, Koji , TSUKADA, Masashi
发明人： KATSUKI, Koji , TSUKADA, Masashi
IPC分类号： A61B5/1473 , A61B5/1486 , G01N27/327 , G01N27/416 , G01N33/66
CPC分类号： C12Q1/006 , A61B5/14532 , A61B5/14865 , A61B5/1495 , A61B5/4839 , A61B5/6849
摘要： Analysis equipment is provided, which is capable of fulfilling a demand for miniaturization and ensuring high sensitivity, and which can be produced easily. The present invention relates to a method of continuously measuring a substrate concentration based on a response when a voltage is applied to a sensor. The present invention includes a response voltage application step of applying a response voltage E2 at which a response attributed to a substrate is obtained and a non-response voltage application step of applying a non-response voltage E1 at which the response attributed to the substrate is not obtained or is not substantially obtained. Preferably, the response voltage application step and the non-response voltage application step are repeated alternately.
摘要翻译：提供分析设备，其能够满足小型化的需求并确保高灵敏度，并且可以容易地制造。本发明涉及一种当将电压施加到传感器时基于响应连续测量衬底浓度的方法。本发明包括：响应电压施加步骤，其施加响应电压E2，在该响应电压E2获得归因于基板的响应;以及非响应电压施加步骤，其施加响应归因于该基板的非响应电压E1 未获得或基本不获得。优选地，交替地重复响应电压施加步骤和非响应电压施加步骤。

3. 发明申请

WO2005066638A8 ANALYTICAL INSTRUMENT HAVING IMPROVED ARRANGEMENT OF REAGENT SECTION AND ANALYTICAL METHOD 审中-公开
标题翻译：具有改进的试剂装置布置和分析方法的分析仪器
公开(公告)号：WO2005066638A8
公开(公告)日：2006-09-21
申请号：PCT/JP2005000153
申请日：2005-01-07
申请人： ARKRAY INC , YAMAOKA HIDEAKI , NAGAKAWA KENJI , HOSHIJIMA MITSUHIRO , KIMURA SADAAKI
发明人： YAMAOKA HIDEAKI , NAGAKAWA KENJI , HOSHIJIMA MITSUHIRO , KIMURA SADAAKI
IPC分类号： C12Q1/00
CPC分类号： C12Q1/006
摘要： An analytical instrument (1) comprises a channel (5) for moving a sample containing blood cells, an introducing port (50) for introducing the sample into the channel (5), a reagent section (51) disposed in the channel (5), and an electron detecting medium (52) for collecting information necessary for analysis of a component to be analyzed in the sample and related to the amount of donated/accepted electrons. A reagent section (51) contains an electron transfer substance for supplying electrons extracted from the component to be analyzed to the electron detecting medium (52), and at least part of the reagent section (51) is disposed near the introducing port (50).
摘要翻译：分析仪器（1）包括用于移动含有血细胞的样品的通道（5），用于将样品引入通道（5）的引入口（50），设置在通道（5）中的试剂部分（51），以及电子检测介质（52），用于收集样品中待分析组分的分析所需的信息，并与所捐赠/接受的电子量相关。试剂部（51）包含用于将从被分析成分提取的电子供给到电子检测介质（52）的电子转移物质，并且所述试剂部（51）的至少一部分配置在所述导入口（50）附近。。

4. 发明申请

WO2009119918A3 FLUID AGITATION METHOD, FLUID AGITATION SYSTEM, AND CARTRIDGE 审中-公开
标题翻译：流体动力学方法，流体动力学系统，和方法
公开(公告)号：WO2009119918A3
公开(公告)日：2009-11-26
申请号：PCT/JP2009056932
申请日：2009-03-27
申请人： ARKRAY INC , UNIV KYOTO , KOTERA HIDETOSHI , SUZUKI TAKAAKI , KANDA KENSUKE , NODA YUICHIRO
发明人： KOTERA HIDETOSHI , SUZUKI TAKAAKI , KANDA KENSUKE , NODA YUICHIRO
IPC分类号： B01F11/00 , B01F11/02 , G01N35/02 , G01N37/00
CPC分类号： B01F11/0266 , G01N33/49
摘要： Provided is a fluid agitation method which agitates a tiny amount of fluid by inducing a rotational flow. The fluid agitation method comprises: a process for containing a fluid in an agitation tank (3) having a wall that has a nonuniform mass distribution; and a process for applying vibrations (F) to said wall while changing the frequency within a prescribed frequency range. The wall is given a nonuniform mass distribution by, for example, arranging multiple thick sections (11 to 18), having different thicknesses, in a ring.
摘要翻译：提供了一种通过引起旋转流动而搅动少量流体的流体搅拌方法。流体搅拌方法包括：在具有不均匀质量分布的壁的搅拌槽（3）中容纳流体的方法; 以及在规定的频率范围内改变频率的同时对所述壁施加振动（F）的工序。通过例如在环中布置具有不同厚度的多个厚壁（11至18），壁被赋予不均匀的质量分布。

5. 发明申请

WO2005118803A9 CONTAINER FOR NUCLEIC ACID EXTRACTION, METHOD OF CLEANING SOLID MATRIX AND RELEVANT CLEANING MECHANISM, AND METHOD OF PURIFYING NUCLEIC ACID 审中-公开
标题翻译：用于核酸提取的容器，清洁固体基质的方法和相关的清洁机理，以及净化核酸的方法
公开(公告)号：WO2005118803A9
公开(公告)日：2007-03-15
申请号：PCT/JP2005010078
申请日：2005-06-01
申请人： ARKRAY INC , KAMATA TATSUO , OHTA SHINICHI , EGAWA KOUJI
发明人： KAMATA TATSUO , OHTA SHINICHI , EGAWA KOUJI
IPC分类号： C12N15/09 , B01L3/00 , C12M1/00 , C12M1/34 , G01N1/34 , G01N1/40
CPC分类号： B01L3/5085 , B01L3/502 , B01L2200/0631 , B01L2300/0609 , G01N1/34 , G01N1/405
摘要： Container for nucleic acid extraction (2) comprising nucleic acid extraction element (20) for extracting of a target nucleic acid from a sample and for adhesion of the extracted nucleic acid and, provided separate from the nucleic acid extraction element (20), a container frame equipped with accommodation vessel (27) for accommodating of the nucleic acid extraction element (20). The nucleic acid extraction element (20) is constructed so as to include, for example, solid matrix (23) for carrying of the target nucleic acid and holding member (20) for holding of the solid matrix (23). Preferably, the solid matrix (23) is held in a form sloping against the vertical axis of the holding member (20).
摘要翻译：用于核酸提取的容器（2），其包含用于从样品中提取靶核酸并用于粘附所提取的核酸的核酸提取元件（20），并且与所述核酸提取元件（20）分开提供容器框架配备有用于容纳核酸提取元件（20）的容纳容器（27）。核酸提取元件（20）被构造为包括例如用于携带用于保持固体基质（23）的靶核酸和保持构件（20）的固体基质（23）。优选地，固体基质（23）以与保持构件（20）的垂直轴线倾斜的形式保持。

6. 发明申请

WO2018080395A1 METHOD OF MANUFACTURING CELLULOSE TEST STRIP 审中-公开
标题翻译：制造纤维素测试条的方法
公开(公告)号：WO2018080395A1
公开(公告)日：2018-05-03
申请号：PCT/SG2017/050532
申请日：2017-10-24
申请人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , ARKRAY, INC.
发明人： YING, Jackie Y. , ZHANG, Yi , BAI, Jianhao , ZHAO, Xinxin
IPC分类号： G01N33/531 , C08J3/28 , C08J5/00 , C08J9/26
CPC分类号： G01N33/558 , G01N33/531
摘要： Disclosed is a method of manufacturing a cellulose test strip having enhanced protein adsorption, the method comprises: (a) providing a cellulose filter paper comprising a plurality of cellulose fibers covered by an inert film; and (b) plasma-depleting a surface of the cellulose filter paper to remove the inert film, thereby forming the cellulose test strip. Also disclosed are lateral flow immunochromatographic assays, cellulose test strips, and assays comprising cellulose test strip.
摘要翻译：公开了一种制造具有增强的蛋白质吸附的纤维素试纸条的方法，所述方法包括：（a）提供包含被惰性膜覆盖的多个纤维素纤维的纤维素滤纸; 和（b）消耗纤维素滤纸表面以除去惰性膜，从而形成纤维素测试条。还公开了侧流免疫色谱测定法，纤维素测试条和包含纤维素测试条的测定。

7. 发明申请

WO2008136465A8 ELECTROPHORESIS CHIP, ELECTROPHORESIS DEVICE, AND SAMPLE ANALYZING METHOD BY CAPILLARY ELECTROPHORESIS METHOD 审中-公开
标题翻译：电泳芯片，电泳装置和通过毛细管电泳法的样品分析方法
公开(公告)号：WO2008136465A8
公开(公告)日：2009-03-12
申请号：PCT/JP2008058206
申请日：2008-04-28
申请人： NAT INST OF ADVANCED IND SCIEN , ARKRAY INC , TANAKA YOSHIHIDE , NAKAYAMA YUSUKE , YONEHARA SATOSHI
发明人： TANAKA YOSHIHIDE , NAKAYAMA YUSUKE , YONEHARA SATOSHI
IPC分类号： G01N27/447 , G01N37/00
CPC分类号： G01N27/44791 , G01N27/44743
摘要： Provided is an electrophoresis chip, which can be reduced in size and simplified and which can analyze a sample highly precisely. The electrophoresis chip comprises an upper substrate (4), a lower substrate (1), an introduction bath (2a), a recovery bath (2b), and a sample analyzing capillary passage (3x). The introduction bath (2a) and the recovery bath (2b) are formed over the lower substrate (1). The sample analyzing capillary passage (3x) affords the communication between the introduction bath (2a) and the recovery bath (2b). The sample or a measurement object is introduced into the introduction bath (2a). A potential difference isestablished between the introduction bath (2a) and the recovery bath (2b), so that the sample is introduced by the electrophoresis directly into the sample analyzing capillary passage (3x). In the sample analyzing capillary passage (3x), the sample analysis is performed while the sample is being continuously fed even during the separation of the sample.
摘要翻译：提供一种电泳芯片，其尺寸可以减小并且简化，并且可以高精度地分析样品。电泳芯片包括上基板（4），下基板（1），引入槽（2a），回收槽（2b）和样品分析毛细管通道（3x）。引入浴（2a）和回收槽（2b）形成在下基板（1）上。样品分析毛细管通道（3x）提供引入浴（2a）和回收浴（2b）之间的连通。将样品或测量对象引入引入浴（2a）中。在引入浴（2a）和回收槽（2b）之间建立了电位差，使得通过电泳将样品引入样品分析毛细管通道（3x）中。在样品分析毛细管通道（3x）中，即使在样品分离期间样品连续进料的同时进行样品分析。

8. 发明专利

TWI608842B 氧化蛋白質分解酵素活性增強劑有权
简体标题：氧化蛋白质分解酶活性增强剂
公开(公告)号：TWI608842B
公开(公告)日：2017-12-21
申请号：TW103105323
申请日：2014-02-18
申请人：愛科來股份有限公司 , ARKRAY, INC. , 學校法人同志社 , THE DOSHISHA
发明人：八木雅之 , YAGI, MASAYUKI , 米井嘉一 , YONEI, YOSHIKAZU , 高山聖史 , TAKAYAMA, KIYOFUMI , 河合博成 , KAWAI, HIROSHIGE
IPC分类号： A61K36/185 , A61K36/28 , A61K36/53 , A61K36/287 , A61K36/534 , A61K36/282 , A61K36/49 , A61K36/61 , A61K36/535 , A61K36/23
CPC分类号： A61K36/89 , A61K36/23 , A61K36/28 , A61K36/282 , A61K36/287 , A61K36/49 , A61K36/53 , A61K36/534 , A61K36/535 , A61K36/61 , C12N9/6424 , C12Y304/21 , A61K2300/00

9. 发明专利

TW201514486A 使用電化學式生物感測器之物質測定方法及測定裝置审中-公开
简体标题：使用电化学式生物传感器之物质测定方法及测定设备
公开(公告)号：TW201514486A
公开(公告)日：2015-04-16
申请号：TW103127114
申请日：2014-08-07
申请人：愛科來股份有限公司 , ARKRAY, INC. , 日本生物工程研究所有限責任公司 , BIOENGINEERING LABORATORIES, LLC
发明人：勝木幸治 , KATSUKI, KOJI
IPC分类号： G01N27/26
CPC分类号： C12Q1/006 , C12Q1/005 , G01N27/3272 , G01N27/3273
摘要：一種使用生物感測器之物質測定方法，包含：在含有絕緣性基板、與形成於該絕緣性基板上的2個以上的電極、及被配置於該電極之至少1個電極上的含有氧化還原酵素的試藥層之電化學測定胞(cell)內導入包含物質的試料，對電極施加電壓，檢測出藉由來自試料內之前述物質的電子之往電極的移動所產生的電荷移動律速電流(electric charge movement-limitation current)，以及根據前述電荷移動律速電流，決定試料中所含的前述物質的濃度。
简体摘要：一种使用生物传感器之物质测定方法，包含：在含有绝缘性基板、与形成于该绝缘性基板上的2个以上的电极、及被配置于该电极之至少1个电极上的含有氧化还原酶的试药层之电化学测定胞(cell)内导入包含物质的试料，对电极施加电压，检测出借由来自试料内之前述物质的电子之往电极的移动所产生的电荷移动律速电流(electric charge movement-limitation current)，以及根据前述电荷移动律速电流，决定试料中所含的前述物质的浓度。

10. 发明专利

TWI460423B 生物感測器及其製造方法有权
简体标题：生物传感器及其制造方法
公开(公告)号：TWI460423B
公开(公告)日：2014-11-11
申请号：TW097142309
申请日：2008-10-31
申请人：愛科來股份有限公司 , ARKRAY, INC.
发明人：藤井朋廣 , FUJII, TOMOHIRO , 日下靖英 , KUSAKA, YASUHIDE
IPC分类号： G01N27/26 , G01N33/48
CPC分类号： G01N27/3271 , B05D5/12 , B32B38/04 , G01N27/3272

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