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1. 发明申请

US20200013269A1 Alarm Initiated Power Disconnects With Backups And Redundancy 审中-公开
公开(公告)号：US20200013269A1
公开(公告)日：2020-01-09
申请号：US15998138
申请日：2018-07-09
申请人： Ronald Walter Sicking , Yvonne Marie Sicking , John Garry Myers
发明人： Ronald Walter Sicking , Yvonne Marie Sicking , John Garry Myers
IPC分类号： G08B17/10 , G08B21/14
摘要： A method of steps and a system of components which detects and responds to smoke, CO, and/or fire hazard emergency alarm signals (loud audio noise and/or bright strobe lights) and then provides a shut-off of electrical power and/or fuel gas (e.g. natural gas or propane) as well as other types of power and energy for safety's sake. The present invention is improved over the current product offerings and state of the art through increasing the reliability of alarm signal detection by utilizing redundancy and providing primary and backup sensor functionality for both of the possible commonly intended alarm signal outputs instead of monitoring for just one. This invention also includes a method of steps and a system which further improves reliability by adding additional redundancy and backups through detecting and responding to the unobvious but real by-product alarm signals which are: 1. the vibration of the audible alarm mechanism and 2. the electricity flowing in or to the activated alarm.

2. 发明申请

US20080044454A1 UNIFORM FILMS FOR RAPID DISSOLVE DOSAGE FORM INCORPORATING TASTE-MASKING COMPOSITIONS 有权
标题翻译：用于快速溶解剂用量的复合膜用于吸收组合物
公开(公告)号：US20080044454A1
公开(公告)日：2008-02-21
申请号：US11775484
申请日：2007-07-10
申请人： Robert Yang , Richard Fuisz , Garry Myers , Joseph Fuisz
发明人： Robert Yang , Richard Fuisz , Garry Myers , Joseph Fuisz
IPC分类号： A61K9/70 , A61K47/30 , A61K9/00
CPC分类号： A61K9/7007 , A61K9/0056 , A61K9/006 , A61K9/14 , A61K9/501 , A61K9/5015 , A61K9/5026 , A61K9/5036 , A61K9/5047 , A61K9/7015 , A61K31/138 , A61K31/192 , A61K31/422 , A61K31/44 , A61K31/4422 , A61K31/443 , A61K31/4545 , A61K31/519 , A61K31/549 , A61K31/567 , A61K31/635 , A61K31/704 , A61K31/7048 , A61K47/02 , A61K47/10 , A61K47/22 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/38 , A61K47/44 , A61K47/46 , B05D3/0254 , B29C47/0004
摘要： The present invention relates to rapid dissolve thin film drug delivery compositions for the oral administration of active components. The active components are provided as taste-masked or controlled-release coated particles uniformly distributed throughout the film composition. The compositions may be formed by wet casting methods, where the film is cast and controllably dried, or alternatively by an extrusion method.
摘要翻译：本发明涉及用于口服给药活性成分的快速溶解薄膜药物递送组合物。活性组分作为均匀分布在整个膜组合物中的掩味或控释包衣颗粒提供。组合物可以通过湿法铸造方法形成，其中膜被浇铸并可控制地干燥，或者通过挤出方法形成。

3. 发明申请

US20060147493A1 Packaging and dispensing of rapid dissolve dosage form 审中-公开
标题翻译：包装和分配快速溶解剂型
公开(公告)号：US20060147493A1
公开(公告)日：2006-07-06
申请号：US10521823
申请日：2003-07-22
申请人： Robert Yang , Richard Fuisz , Garry Myers , Joseph Fuisz
发明人： Robert Yang , Richard Fuisz , Garry Myers , Joseph Fuisz
IPC分类号： A61K47/00
CPC分类号： A61K9/7007 , A61J1/03 , A61J3/078 , A61K8/02 , A61K31/4545 , A61K2800/87 , A61Q11/00 , B65B5/06 , B65B11/50 , B65B25/06
摘要： An oral dosage delivery vehicle comprising an edible film including a uniformly distributed active ingredient, wherein said film comprises dosage units releasably joined by one or more weakened sections, which permit said dosage units to be detached from said film.
摘要翻译：一种口服剂量递送载体，其包含包含均匀分布的活性成分的可食用膜，其中所述膜包含通过一个或多个弱化部分可释放地连接的剂量单位，其允许所述剂量单元从所述膜分离。

4. 发明申请

US20080000925A1 Packet dispenser 审中-公开
标题翻译：包分配器
公开(公告)号：US20080000925A1
公开(公告)日：2008-01-03
申请号：US11824153
申请日：2007-06-29
申请人： Richard Fuisz , Bruce Detwiler , Garry Myers , Pradeep Sanghvi , Madhusudan Hariharan , Laura Moss
发明人： Richard Fuisz , Bruce Detwiler , Garry Myers , Pradeep Sanghvi , Madhusudan Hariharan , Laura Moss
IPC分类号： B65H3/00
CPC分类号： G07F11/045 , B65D75/5805 , B65D83/0847 , B65D2215/02
摘要： The packet dispenser includes a container structure having an interior cavity. The cavity has a sufficient dimension such that a packet structure may be stored therein. The container structure has an opening to the cavity through which the packet structure can be removed therefrom. A tear structure is connected to the container structure such that the packet structure may contact the tear structure to tear a portion thereof when the packet structure is removed from the cavity.
摘要翻译：分组分配器包括具有内部空腔的容器结构。空腔具有足够的尺寸，使得可以在其中存储分组结构。容器结构具有通向空腔的开口，通过该开口可以从其中移除包装结构。撕裂结构连接到容器结构，使得当分组结构从空腔移除时，分组结构可以接触撕裂结构以撕裂其部分。

5. 发明申请

US20070281003A1 Polymer-Based Films and Drug Delivery Systems Made Therefrom 审中-公开
标题翻译：基于聚合物的薄膜和药物输送系统
公开(公告)号：US20070281003A1
公开(公告)日：2007-12-06
申请号：US11674223
申请日：2007-02-13
申请人： Richard Fuisz , Joseph Fuisz , Garry Myers , Robert Yang , Pradeep Sanghvi
发明人： Richard Fuisz , Joseph Fuisz , Garry Myers , Robert Yang , Pradeep Sanghvi
IPC分类号： A61K9/70
CPC分类号： B29C39/003 , A61J3/00 , A61J2200/20 , A61K9/006 , A61K9/7007 , B29C39/14 , B29C71/02 , F26B13/104
摘要： The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component which includes polyethylene oxide, optionally blended with at least one additional polymer. The films may alternatively contain a polymer component which includes polyvinyl alcohol, optionally blended with at least one additional polymer. The films also may contain a pharmaceutical and/or cosmetic active agent.
摘要翻译：本发明涉及其制备的薄膜产品及其制备方法，其表现出非自聚集均匀的异质性。期望地，膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。膜包含聚合物组分，其包括聚环氧乙烷，任选地与至少一种另外的聚合物共混。膜可以备选地包含聚合物组分，其包括聚乙烯醇，任选地与至少一种另外的聚合物共混。膜也可以含有药物和/或美容活性剂。

6. 发明申请

US20070149731A1 PH modulated films for delivery of actives 有权
标题翻译： PH调制膜用于递送活性物质
公开(公告)号：US20070149731A1
公开(公告)日：2007-06-28
申请号：US11639013
申请日：2006-12-14
申请人： Garry Myers
发明人： Garry Myers
IPC分类号： A61L33/00 , A61F13/02 , B05D7/00 , C08F4/06
CPC分类号： A61K9/7007 , A61K9/0036 , A61K9/006 , A61K9/1635 , A61K9/1652 , A61K9/7015 , A61K47/02 , A61K47/12
摘要： The invention relates to pH modulated films and methods of their preparation. The film compositions include at least one component having a non-neutral pH when combined with water; and a pH modulated polymer system selected to reduce or prevent synerisis when combined with the non-neutral component in combination with aqueous media. The films demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, extrusion process, or other process that maintains the required uniformity of the film.
摘要翻译：本发明涉及pH调节膜及其制备方法。膜组合物包含至少一种与水结合时具有非中性pH的组分; 以及当与非水性介质组合时与非中性组分组合时选择的pH调节聚合物体系来减少或防止协同作用。这些电影表现出非自我聚集均匀的异质性。理想地，膜在水中分解并且可以通过受控的干燥过程，挤出工艺或维持膜所需的均匀性的其它方法形成。

7. 发明申请

US20070122455A1 Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions 有权
标题翻译：包含抗粘合剂的快速溶解剂型的均匀薄膜
公开(公告)号：US20070122455A1
公开(公告)日：2007-05-31
申请号：US11517982
申请日：2006-09-08
申请人： Garry Myers , Pradeep Sanghvi , Andrew Verall , Vimala Francis , Laura Moss
发明人： Garry Myers , Pradeep Sanghvi , Andrew Verall , Vimala Francis , Laura Moss
IPC分类号： A61K47/00
CPC分类号： A61K9/7007 , A23L33/10 , A23L33/105 , A23L33/15 , A23L33/16 , A23P20/20 , A23P30/10 , A23V2002/00 , A61K9/0056 , A61K9/006 , A61K31/355 , A61K31/485 , A61K47/02 , A61K47/12 , A61K47/14 , A61K47/22 , A61K47/34 , A61K47/36 , A61K47/38 , A23V2200/30 , A23V2200/324 , A23V2250/21 , A23V2250/70 , A23V2250/156
摘要： The present invention relates to water-soluble films incorporating anti-tacking agents and methods of their preparation. Anti-tacking agents may improve the flow characteristics of the compositions and thereby reduce the problem of film adhering to a user's mouth or to other units of film. In particular, the present invention relates to edible water-soluble delivery systems in the form of a film composition including a water-soluble polymer, an active component selected from cosmetic agents, pharmaceutical agents, vitamins, bioactive agents and combinations thereof and at least one anti-tacking agent.
摘要翻译：本发明涉及含有抗粘连剂的水溶性薄膜及其制备方法。防粘剂可以改善组合物的流动特性，从而减少膜粘附到使用者的口部或其它单元的膜的问题。特别地，本发明涉及包含水溶性聚合物，选自化妆剂，药剂，维生素，生物活性剂及其组合的活性组分的薄膜组合物形式的食用水溶性递送系统和至少一种防粘剂。

8. 发明授权

US5891845A Drug delivery systems utilizing liquid crystal structures 失效
标题翻译：使用液晶结构的药物输送系统
公开(公告)号：US5891845A
公开(公告)日：1999-04-06
申请号：US975827
申请日：1997-11-21
申请人： Garry Myers
发明人： Garry Myers
IPC分类号： A61K47/34 , A61K9/00 , A61K9/127 , A61K9/14 , A61K9/20 , A61K9/48 , A61K31/355 , A61K31/455 , A61K31/554 , A61K38/00 , A61K38/13 , A61K31/44 , A61K31/55
CPC分类号： A61K9/146 , A61K31/355 , A61K38/13 , A61K9/1274 , A61K9/0092 , A61K9/2013 , A61K9/2072 , A61K9/4858
摘要： Vitamin E TPGS/drug compositions and methods are provided which obviate the need for surfactants or non-evaporated co-solvents because the active drug component is dissolved directly into Vitamin E TPGS to form a true molecular solution--not an emulsion or a micro-emulsion. The invention provides a slowly dissolving TPGS/Drug matrix that absorbs gastrointestinal fluid into the matrix at the dosage form/fluid interface, where a gel-like liquid crystal is formed. This gel front forms a liquid crystal boundary where drug dissolution is highest. At this liquid crystal/GI fluid boundary, a synchronization takes place in which the rate of formation of liquid crystals equals the dissolution rate of liquid crystals at the water interface, thereby giving controlled order release of the drug into the GI tract. The rate of dissolution is also controlled by the geometry of the dosage form. The solid Vitamin E TPGS/drug matrices of the invention can be solidified and compressed into tablets or filled into capsules, with other excipients, binders and/or fillers. The solid TPGS/drug solution of the invention also can be made into an immediate release liquid formulation upon addition of water, or into a controlled release system solid tablet by the use of impermeable or semi-permeable barriers or coatings surrounding portions of the tablet.
摘要翻译：提供维生素E TPGS /药物组合物和方法，其消除了对表面活性剂或非蒸发共溶剂的需要，因为活性药物组分直接溶解于维生素E TPGS中以形成真正的分子溶液 - 而不是乳液或微乳液。本发明提供了缓慢溶解的TPGS /药物基质，其在形成凝胶状液晶的剂型/流体界面处将胃肠液吸收到基质中。该凝胶前体形成药物溶出度最高的液晶边界。在该液晶/ GI液体边界处，发生液晶的形成速率等于水界面处的液晶的溶解速率的同步，从而将药物控制释放到GI道中。溶解速率也可以通过剂型的几何形状来控制。本发明的固体维生素E TPGS /药物基质可以固化并压制成片剂或者与其它赋形剂，粘合剂和/或填充剂一起填充到胶囊中。本发明的固体TPGS /药物溶液还可以通过加入水制成立即释放的液体制剂，或通过使用围绕片剂部分的不渗透的或半渗透的屏障或涂层，进入控释系统的固体片剂。

9. 发明申请

US20120107402A1 PROCESS FOR ANALYZING AND ESTABLISHING DOSAGE SIZE IN AN INGESTIBLE FILM 审中-公开
标题翻译：用于分析和建立不可消耗胶片剂量大小的方法
公开(公告)号：US20120107402A1
公开(公告)日：2012-05-03
申请号：US12915849
申请日：2010-10-29
申请人： Garry Myers , Beuford A. Bogue , Madhu Hariharan
发明人： Garry Myers , Beuford A. Bogue , Madhu Hariharan
IPC分类号： A61K9/14 , A61P1/08 , A61P25/04 , A23L1/302 , A23L1/226 , A23L1/30 , A23L1/236 , A23L1/22 , A61K47/38 , G01N33/02
CPC分类号： A61K9/0056 , A61K9/006 , A61K9/7007 , A61K47/10
摘要： The present invention is directed to a method of analyzing and establishing a proper dosage size in ingestible films for providing a more precise dosage delivery of an active ingredient.
摘要翻译：本发明涉及一种在可摄取的薄膜中分析和建立适当的剂量大小以提供活性成分更精确的剂量递送的方法。

10. 发明申请

US20070190157A1 Film lined packaging and method of making same 审中-公开
标题翻译：薄膜衬里包装及其制作方法
公开(公告)号：US20070190157A1
公开(公告)日：2007-08-16
申请号：US11655376
申请日：2007-01-19
申请人： Pradeep Sanghvi , Garry Myers , Joseph Fuisz , Richard Fuisz
发明人： Pradeep Sanghvi , Garry Myers , Joseph Fuisz , Richard Fuisz
IPC分类号： A61K9/14
CPC分类号： A61K9/009 , A23G3/56 , A23P10/30 , A24B13/00 , A61K9/0056 , A61K9/7007 , B65D65/46 , B65D85/808
摘要： The present invention relates to packaging in the form of a pouch, which may contain active substances, such as food products, pharmaceutical agents, nutraceuticals and cosmetic agents, or the like. More specifically, in some embodiments, the present invention provides a pouch, which includes at least one porous substrate encompassing a closed volume and at least one water-soluble film at least partially covering the at least one porous substrate. The pouch may contain an active substance within the closed volume, as well as an active substance in the water-soluble film. The present invention also relates to methods of making and using the pouches.
摘要翻译：本发明涉及袋子形式的包装，其可以含有活性物质，如食品，药剂，保健品和化妆品等。更具体地，在一些实施方案中，本发明提供了一种袋，其包括至少一个包含闭合体积的多孔基材和至少部分地覆盖至少一种多孔基材的至少一种水溶性薄膜。该袋可以在封闭体积内含有活性物质，以及水溶性膜中的活性物质。本发明还涉及制造和使用袋的方法。

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