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1. 发明申请

US20100297232A1 ONDANSETRON FILM COMPOSITIONS 审中-公开
标题翻译： ONDANSETRON薄膜组合物
公开(公告)号：US20100297232A1
公开(公告)日：2010-11-25
申请号：US12468434
申请日：2009-05-19
申请人： Garry L. Myers , Madhusudan Hariharan , Pradeep Sanghvi
发明人： Garry L. Myers , Madhusudan Hariharan , Pradeep Sanghvi
IPC分类号： A61K9/10 , A61K47/02 , A61K31/4178
CPC分类号： A61K31/4178 , A23G4/06 , A61K9/006
摘要： The present invention relates to products and methods of making products having a taste masked active component. In particular, the present invention relates to taste-masked film dosage forms including at least one active component and a slow dissolving basic composition.
摘要翻译：本发明涉及制备具有掩味活性成分的产品的产品和方法。特别地，本发明涉及包含至少一种活性成分和缓慢溶解的碱性组合物的掩味膜剂型。

2. 发明申请

US20100178254A1 UNIT ASSEMBLY FOR MULTIPLE FILM DOSAGES, APPARATUS, AND METHODS 审中-公开
标题翻译：单位大会用于多个片剂，装置和方法
公开(公告)号：US20100178254A1
公开(公告)日：2010-07-15
申请号：US12686531
申请日：2010-01-13
申请人： Madhusudan Hariharan , Richard C. Fuisz
发明人： Madhusudan Hariharan , Richard C. Fuisz
IPC分类号： A61P43/00 , A61K9/00 , B26D3/00 , B26D9/00
CPC分类号： A23P20/20 , A61K9/0056 , A61K9/7007 , Y10T83/0448 , Y10T83/0524 , Y10T83/889
摘要： A unit assembly including a plurality of individual film strips, each film strip having an active within a polymer matrix, the film strips having respective perimetrical edges, the plurality of individual film strips being alternatingly positioned next to one another such that a film strip perimetrical edge is at least partially offset from a subsequent film strip perimetrical edge, wherein the respective perimetrical edges of the film strips are directly adjacent to each other.
摘要翻译：一种单元组件，其包括多个单独的薄膜条，每个胶片带在聚合物基质内具有活性物质，所述胶片条具有相应的周边边缘，所述多个单独的胶片条彼此交替地定位，使得胶片条周边至少部分地偏离随后的胶片条周边边缘，其中胶片条的各个周边边缘彼此直接相邻。

3. 发明申请

US20110033542A1 SUBLINGUAL AND BUCCAL FILM COMPOSITIONS 审中-公开
标题翻译：次级和薄膜组成
公开(公告)号：US20110033542A1
公开(公告)日：2011-02-10
申请号：US12537580
申请日：2009-08-07
申请人： Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , B. Arlie Bogue , Pradeep Sanghvi , Madhusudan Hariharan
发明人： Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , B. Arlie Bogue , Pradeep Sanghvi , Madhusudan Hariharan
IPC分类号： A61K9/00 , A61K31/485
CPC分类号： A61K9/006 , A61K9/0056 , A61K9/7007 , A61K31/485 , A61K47/10 , A61K47/12
摘要： The present invention relates to products and methods for treatment of various symptoms in a patient, including treatment of pain suffered by a patient. The invention more particularly relates to self-supporting dosage forms which provide an active agent while providing sufficient buccal adhesion of the dosage form. Further, the present invention provides a dosage form which is useful in reducing the likelihood of diversion abuse of the active agent.
摘要翻译：本发明涉及治疗患者各种症状的产品和方法，包括治疗患者所遭受的疼痛。本发明更具体地涉及提供活性剂同时提供剂型的足够的颊粘附的自支撑剂型。此外，本发明提供了可用于降低活性剂的转移滥用可能性的剂型。

4. 发明申请

US20110033541A1 SUBLINGUAL AND BUCCAL FILM COMPOSITIONS 有权
标题翻译：次级和薄膜组成
公开(公告)号：US20110033541A1
公开(公告)日：2011-02-10
申请号：US12537571
申请日：2009-08-07
申请人： Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , B. Arlie Bogue , Pradeep Sanghvi , Madhusudan Hariharan
发明人： Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , B. Arlie Bogue , Pradeep Sanghvi , Madhusudan Hariharan
IPC分类号： A61K9/10 , A61K31/4355
CPC分类号： A61K31/485 , A61K9/0056 , A61K9/006 , A61K9/7007 , A61K31/4355 , A61K31/46 , A61K47/10 , A61K47/12 , A61K47/22 , A61K47/26 , A61K47/32 , A61K47/34 , A61K47/38 , A61K2300/00
摘要： The present invention relates to products and methods for treatment of narcotic dependence in a user. The invention more particularly relates to self-supporting dosage forms which provide an active agent for treating narcotic dependence while providing sufficient buccal adhesion of the dosage form.
摘要翻译：本发明涉及用于治疗麻醉药物依赖性的产品和方法。本发明更具体地涉及自支持剂型，其提供用于治疗麻醉依赖性的活性剂，同时提供剂型的足够的颊粘连。

5. 发明申请

US20130281481A1 SUBLINGUAL AND BUCCAL FILM COMPOSITIONS 审中-公开
公开(公告)号：US20130281481A1
公开(公告)日：2013-10-24
申请号：US13923749
申请日：2013-06-21
申请人： Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , B. Arlie Bogue , Pradeep Sanghvi , Madhusudan Hariharan
发明人： Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , B. Arlie Bogue , Pradeep Sanghvi , Madhusudan Hariharan
IPC分类号： A61K31/485
CPC分类号： A61K31/485 , A61K9/0056 , A61K9/006 , A61K9/7007 , A61K31/4355 , A61K31/46 , A61K47/10 , A61K47/12 , A61K47/22 , A61K47/26 , A61K47/32 , A61K47/34 , A61K47/38 , A61K2300/00
摘要： The present invention relates to products and methods for treatment of narcotic dependence in a user. The invention more particularly relates to self-supporting dosage forms which provide an active agent for treating narcotic dependence while providing sufficient buccal adhesion of the dosage form.

6. 发明申请

US20100040727A1 Method for Improving Uniformity of Content in Edible Film Manufacturing 审中-公开
标题翻译：提高食用膜制造中内容一致性的方法
公开(公告)号：US20100040727A1
公开(公告)日：2010-02-18
申请号：US12193079
申请日：2008-08-18
申请人： Garry L. Myers , Madhusudan Hariharan , Pradeep Sanghvi , Alex Szopinski , Patrick Dailey
发明人： Garry L. Myers , Madhusudan Hariharan , Pradeep Sanghvi , Alex Szopinski , Patrick Dailey
IPC分类号： A61K9/70 , A23P1/10
CPC分类号： A61K9/7007 , A23P30/00 , A61K31/485
摘要： The present invention relates to a method of making a film composition with an improved uniformity of active composition. The invention includes a method including the steps of forming a flowable film composition comprising an edible water-soluble polymer, a polar solvent and a particulate active suspended therein, where the ratio of solids to liquids is at least about 95 to about 5 and where the composition comprises a mixture having compositional uniformity per unit volume; directing the flowable film composition to a transfer trough, the transfer trough including a first rotating roller and a movable transfer substrate upon which to form the film; and maintaining uniformity of the flowable film composition during the residence time in the trough by maintaining the rate of composition entering the transfer trough and the level of the flowable film composition in the transfer trough at a substantially constant level. Methods of administering the active are also contemplated.
摘要翻译：本发明涉及制备具有改善的活性组合物均匀性的薄膜组合物的方法。本发明包括一种方法，其包括形成包含可食用水溶性聚合物，极性溶剂和悬浮于其中的颗粒活性物质的可流动膜组合物的步骤，其中固体与液体的比例至少为约95至约5，组合物包含具有每单位体积的组成均匀性的混合物; 将可流动膜组合物引导到转移槽，转移槽包括第一旋转辊和可移动转移基底，在其上形成膜; 并且通过保持进入转移槽的组合物的速率和转移槽中的可流动的膜组合物的水平基本上恒定的水平，保持在槽中的停留时间期间可流动的膜组合物的均匀性。也考虑施用活性物质的方法。

7. 发明申请

US20080000925A1 Packet dispenser 审中-公开
标题翻译：包分配器
公开(公告)号：US20080000925A1
公开(公告)日：2008-01-03
申请号：US11824153
申请日：2007-06-29
申请人： Richard Fuisz , Bruce Detwiler , Garry Myers , Pradeep Sanghvi , Madhusudan Hariharan , Laura Moss
发明人： Richard Fuisz , Bruce Detwiler , Garry Myers , Pradeep Sanghvi , Madhusudan Hariharan , Laura Moss
IPC分类号： B65H3/00
CPC分类号： G07F11/045 , B65D75/5805 , B65D83/0847 , B65D2215/02
摘要： The packet dispenser includes a container structure having an interior cavity. The cavity has a sufficient dimension such that a packet structure may be stored therein. The container structure has an opening to the cavity through which the packet structure can be removed therefrom. A tear structure is connected to the container structure such that the packet structure may contact the tear structure to tear a portion thereof when the packet structure is removed from the cavity.
摘要翻译：分组分配器包括具有内部空腔的容器结构。空腔具有足够的尺寸，使得可以在其中存储分组结构。容器结构具有通向空腔的开口，通过该开口可以从其中移除包装结构。撕裂结构连接到容器结构，使得当分组结构从空腔移除时，分组结构可以接触撕裂结构以撕裂其部分。

8. 发明申请

US20140005218A1 SUBLINGUAL AND BUCCAL FILM COMPOSITIONS 审中-公开
公开(公告)号：US20140005218A1
公开(公告)日：2014-01-02
申请号：US13964975
申请日：2013-08-12
申请人： Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , Beuford A. Bogue , Pradeep Sanghvi , Madhusudan Hariharan
发明人： Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , Beuford A. Bogue , Pradeep Sanghvi , Madhusudan Hariharan
IPC分类号： A61K9/00 , A61K31/485
CPC分类号： A61K31/485 , A61K9/0056 , A61K9/006 , A61K9/7007 , A61K31/4355 , A61K31/46 , A61K47/10 , A61K47/12 , A61K47/22 , A61K47/26 , A61K47/32 , A61K47/34 , A61K47/38 , A61K2300/00
摘要： The present invention relates to products and methods for treatment of narcotic dependence in a user. The invention more particularly relates to self-supporting dosage forms which provide an active agent for treating narcotic dependence while providing sufficient buccal adhesion of the dosage form.

9. 发明授权

US08475832B2 Sublingual and buccal film compositions 有权
标题翻译：舌下和口腔胶片组成
公开(公告)号：US08475832B2
公开(公告)日：2013-07-02
申请号：US12537571
申请日：2009-08-07
申请人： Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , B. Arlie Bogue , Pradeep Sanghvi , Madhusudan Hariharan
发明人： Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , B. Arlie Bogue , Pradeep Sanghvi , Madhusudan Hariharan
IPC分类号： A61F13/00 , A61K9/14 , A61K31/44
CPC分类号： A61K31/485 , A61K9/0056 , A61K9/006 , A61K9/7007 , A61K31/4355 , A61K31/46 , A61K47/10 , A61K47/12 , A61K47/22 , A61K47/26 , A61K47/32 , A61K47/34 , A61K47/38 , A61K2300/00
摘要： The present invention relates to products and methods for treatment of narcotic dependence in a user. The invention more particularly relates to self-supporting dosage forms which provide an active agent for treating narcotic dependence while providing sufficient buccal adhesion of the dosage form.
摘要翻译：本发明涉及用于治疗麻醉药物依赖性的产品和方法。本发明更具体地涉及自支持剂型，其提供用于治疗麻醉依赖性的活性剂，同时提供剂型的足够的颊粘连。

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