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1. 发明授权

US06610003B1 Intraluminal radiation treatment system 有权
标题翻译：管腔内放射治疗系统
公开(公告)号：US06610003B1
公开(公告)日：2003-08-26
申请号：US09444234
申请日：1999-11-19
申请人： Raphael F. Meloul , Richard A. Hillstead , George K. Bonnoitt, Jr. , Martin B. Tobias
发明人： Raphael F. Meloul , Richard A. Hillstead , George K. Bonnoitt, Jr. , Martin B. Tobias
IPC分类号： A61M2901
CPC分类号： A61N5/1002 , A61N5/1007 , A61N2005/1008
摘要： A transfer device and catheter assembly for the delivery of treatment elements to a selected location within the intraluminal passageways of a patient as part of an intraluminal radiation system. The transfer device includes a gate member that permits the treatment elements to have the transfer device only if the catheter is attached thereto. A pressure indicator provides a visual indication of the fluid pressure within the transfer device, and provides for a release of the fluid if the pressure exceeds a predetermined pressure. The catheter also includes detents to secure it to the transfer device and which must be manually activated to remove the catheter from the transfer device. The transfer device includes circuiting that determines whether the treating elements reside within the transfer device based upon the reflectivity of the treating elements. A method for determining whether treating elements reside in the catheter is also disclosed.
摘要翻译：用于将治疗元件递送到患者的管腔内通道内的选定位置作为管腔内辐射系统的一部分的转移装置和导管组件。转移装置包括仅在导管附接到处理元件时才允许处理元件具有转印装置的浇口构件。压力指示器提供传送装置内的流体压力的视觉指示，并且如果压力超过预定压力则提供流体的释放。导管还包括棘爪以将其固定到转移装置，并且其必须被手动地启动以从转移装置移除导管。转移装置包括基于处理元件的反射率确定处理元件是否位于转移装置内的电路。还公开了一种用于确定处理元件是否存在于导管中的方法。

2. 发明授权

US5899882A Catheter apparatus for radiation treatment of a desired area in the vascular system of a patient 失效
标题翻译：用于放射治疗患者血管系统中所需区域的导管装置
公开(公告)号：US5899882A
公开(公告)日：1999-05-04
申请号：US628231
申请日：1996-04-04
申请人： Ron Waksman , Thomas D. Weldon , Raphael F. Meloul , Richard A. Hillstead , Jonathan J. Rosen , George K. Bonnoitt, Jr. , David S. Halpern , Charles E. Larsen , Ian R. Crocker
发明人： Ron Waksman , Thomas D. Weldon , Raphael F. Meloul , Richard A. Hillstead , Jonathan J. Rosen , George K. Bonnoitt, Jr. , David S. Halpern , Charles E. Larsen , Ian R. Crocker
IPC分类号： A61N5/00 , A61F2/958 , A61M25/00 , A61M29/02 , A61M36/04 , A61N5/10 , A61M29/00
CPC分类号： A61M37/0069 , A61M25/1002 , A61N5/1002 , A61N5/1007 , A61M2025/0037 , A61M2025/0039 , A61M2025/004 , A61M25/0029 , A61M25/1006 , A61N2005/1003 , A61N2005/1005 , A61N2005/1008 , A61N2005/1023
摘要： Apparatus and method are described for delivery of a treating element, such as a radiation source, through a catheter to a desired site in the intraluminal passageways of a patient, such as a coronary artery, for inhibiting the formation of scar tissue such as may occur in restenosis following balloon angioplasty. The apparatus includes an elongated flexible catheter tube having proximal and distal end portions, with a lumen extending therebetween, and a diameter sufficiently small for insertion in to a patient's intraluminal passageways. One or more treating elements, such as a capsule or pellet containing radioactive material, is positionable within the lumen and movable between the proximal and distal end portions under the force of liquid flowing through the lumen. A method for using such apparatus, including a method for using such apparatus simultaneously with a balloon angioplasty procedure, is disclosed.
摘要翻译：描述了用于将治疗元件（例如辐射源）通过导管递送到患者（例如冠状动脉）的管腔内通道中用于抑制形成瘢痕组织的可能发生的装置和方法在球囊血管成形术后再狭窄。该装置包括细长的柔性导管，其具有近端部分和远端部分，其间具有内腔，并且其直径足够小以插入病人的管腔内通道。一个或多个处理元件，例如包含放射性物质的胶囊或丸粒，可定位在内腔内并且在液体流过内腔的力的作用下在近端部分和远端部分之间移动。公开了一种使用这种装置的方法，包括与球囊血管成形术程序同时使用这种装置的方法。

3. 发明授权

US06261219B1 Intraluminal radiation treatment system 有权
标题翻译：管腔内放射治疗系统
公开(公告)号：US06261219B1
公开(公告)日：2001-07-17
申请号：US09304752
申请日：1999-05-04
申请人： Raphael F. Meloul , Richard A. Hillstead , George K. Bonnoitt, Jr. , Martin B. Tobias , David S. Halpern , Roelof Trip
发明人： Raphael F. Meloul , Richard A. Hillstead , George K. Bonnoitt, Jr. , Martin B. Tobias , David S. Halpern , Roelof Trip
IPC分类号： A61N500
CPC分类号： A61N5/1002 , A61N5/1007 , A61N2005/1008
摘要： This invention is a transfer device and catheter assembly for the delivery of treatment elements to a selected location within the intraluminal passageways of a patient as part of an intraluminal radiation system. The transfer device includes a gate member that permits the treatment elements to leave the transfer device only if the catheter is attached thereto. A pressure indicator provides a visual indication of the fluid pressure within the transfer device, and a pressure relief valve provides for a release of the fluid if the pressure exceeds a predetermined pressure. Transfer device also includes a treatment element detection system, low power indicator, a counter system, and an electromagnetic locking mechanism to prevent the opening or closing of the gate member when less than all of the treatment elements are in the transfer device.
摘要翻译：本发明是用于将治疗元件递送到患者的管腔内通道内的选定位置作为管腔内辐射系统的一部分的转移装置和导管组件。转移装置包括仅当导管附接到其上时才允许治疗元件离开转移装置的门构件。压力指示器提供传送装置内的流体压力的可视指示，并且如果压力超过预定压力，则泄压阀提供流体的释放。传送装置还包括处理元件检测系统，低功率指示器，计数器系统和电磁锁定机构，以在小于所有处理元件在传送装置中时防止门构件的打开或关闭。

4. 发明授权

US09550303B2 Shaving device 有权
标题翻译：剃须装置
公开(公告)号：US09550303B2
公开(公告)日：2017-01-24
申请号：US14977560
申请日：2015-12-21
申请人： Ruairidh Robertson , David Carpenter , Alan Kenneth Stratton , George K. Bonnoitt, Jr.
发明人： Ruairidh Robertson , David Carpenter , Alan Kenneth Stratton , George K. Bonnoitt, Jr.
IPC分类号： B26B21/10 , B26B21/52 , B26B21/22 , B26B21/24 , B26B21/40 , B26B21/44
CPC分类号： B26B21/521 , B26B21/10 , B26B21/165 , B26B21/22 , B26B21/225 , B26B21/24 , B26B21/4018 , B26B21/4062 , B26B21/44 , B26B21/443 , B26B21/52 , B26B21/523
摘要： A shaving device comprising a head assembly having a support member and a blade cartridge. The support member is configured to be detachably coupled to a handle. The blade cartridge has a first and a second face wherein at least one of the first or second faces comprises at least one razor blade. The blade cartridge is configured to be rotatably coupled to the support member about a pivot axis such that the blade cartridge is pivotable by a user to select one of the first or second faces.
摘要翻译：一种剃须装置，包括具有支撑构件和刀片盒的头组件。支撑构件被构造成可拆卸地联接到手柄。刀片仓具有第一和第二面，其中第一或第二面中的至少一个包括至少一个剃刀刀片。刀片盒被构造成围绕枢转轴线可旋转地联接到支撑构件，使得刀片盒可由使用者枢转以选择第一或第二面之一。

5. 发明授权

US06306074B1 Method and apparatus for radiation treatment of a desired area in the vascular system of a patient 有权
标题翻译：辐射治疗患者血管系统中所需区域的方法和装置
公开(公告)号：US06306074B1
公开(公告)日：2001-10-23
申请号：US09304783
申请日：1999-05-04
申请人： Ron Waksman , Thomas D. Weldon , Raphael F. Meloul , Richard A. Hillstead , Jonathan J. Rosen , George K. Bonnoitt, Jr. , David S. Halpern , Charles E. Larsen , Ian R. Crocker
发明人： Ron Waksman , Thomas D. Weldon , Raphael F. Meloul , Richard A. Hillstead , Jonathan J. Rosen , George K. Bonnoitt, Jr. , David S. Halpern , Charles E. Larsen , Ian R. Crocker
IPC分类号： A61M2902
CPC分类号： A61M37/0069 , A61M25/0029 , A61M25/1002 , A61M25/1006 , A61M2025/0037 , A61M2025/0039 , A61M2025/004 , A61N5/1002 , A61N5/1007 , A61N2005/1003 , A61N2005/1005 , A61N2005/1008 , A61N2005/1023
摘要： Apparatus and method are described for delivery of a treating element, such as a radiation source, through a catheter to a desired site in the intraluminal passageways of a patient, such as a coronary artery, for inhibiting the formation of scar tissue such as may occur in restenosis following balloon angioplasty. The apparatus includes an elongated flexible catheter tube having proximal and distal end portions, with a lumen extending therebetween, and a diameter sufficiently small for insertion in to a patient's intraluminal passageways. One or more treating elements, such as a capsule or pellet containing radioactive material, is positionable within the lumen and movable between the proximal and distal end portions under the force of liquid flowing through the lumen. A method for using such apparatus, including a method for using such apparatus simultaneously with a balloon angioplasty procedure, is disclosed.
摘要翻译：描述了用于将治疗元件（例如辐射源）通过导管递送到患者（例如冠状动脉）的管腔内通道中用于抑制形成瘢痕组织的可能发生的装置和方法在球囊血管成形术后再狭窄。该装置包括细长的柔性导管，其具有近端部分和远端部分，其间具有内腔，并且其直径足够小以插入病人的管腔内通道。一个或多个处理元件，例如包含放射性物质的胶囊或丸粒，可定位在内腔内并且在液体流过内腔的力的作用下在近端部分和远端部分之间移动。公开了一种使用这种装置的方法，包括与球囊血管成形术程序同时使用这种装置的方法。

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