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1. 发明授权

US09870538B2 Optimizing placement of advertisements across multiple platforms 有权
公开(公告)号：US09870538B2
公开(公告)日：2018-01-16
申请号：US12714642
申请日：2010-03-01
申请人： Chen-Huan Jerry Yang
发明人： Chen-Huan Jerry Yang
IPC分类号： G06Q30/00 , G06Q10/00 , G06Q30/02 , H04N21/443 , H04N21/45 , H04N21/81
CPC分类号： G06Q10/00 , G06Q30/00 , G06Q30/0244 , H04N21/4431 , H04N21/4532 , H04N21/812
摘要： A computer implemented method, system, and/or computer program product manage advertisement placement across disparate advertisement media platforms. The disparate advertisement media platforms are each coupled to a respective monitoring application. The monitoring applications monitor activities occurring within their respective advertisement media. Data describing the monitored activities is input to a business intelligence core. In response to one or more of the monitoring applications detecting a real-time event related to a specific subject, the business intelligence core adjusts an amount of electronic advertisement in one or more of the disparate advertising media.

2. 发明授权

US09347929B2 Controlling translocation through nanopores with fluid wall 有权
标题翻译：通过具有流体壁的纳米孔控制易位
公开(公告)号：US09347929B2
公开(公告)日：2016-05-24
申请号：US13400472
申请日：2012-02-20
申请人： Michael Mayer , Erik Yusko , Jerry Yang
发明人： Michael Mayer , Erik Yusko , Jerry Yang
IPC分类号： G01N27/26 , G01N33/487 , B82Y30/00 , C12Q1/68
CPC分类号： G01N33/48721 , B82Y30/00 , C12Q1/6869 , G01N15/1209 , G01N2015/0038 , C12Q2563/131 , C12Q2565/631
摘要： Improved resolution and detection of nanoparticles are achieved when a nanopore connecting liquid compartments in a device running on the Coulter principle is provided with fluid lipid walls. The fluid lipid walls are made of a lipid bilayer, and preferably include lipid anchored mobile ligands as part of the lipid bilayer. By varying the nature and concentration of the mobile ligand in the lipid bilayer, multifunctional coatings of lipids are provided.
摘要翻译：当在Coulter原理上运行的装置中的纳米孔连接液体隔室设置有流体脂质壁时，实现了纳米颗粒的改进的分辨率和检测。流体脂质壁由脂质双层制成，优选包括脂质锚定的移动配体作为脂质双层的一部分。通过改变脂质双层中的移动配体的性质和浓度，提供脂质的多功能涂层。

3. 发明申请

US20120202286A1 rbLIF PROTEIN FOR USE IN EMBRYONIC STEM CELL CULTURES 审中-公开
标题翻译： rbLIF蛋白用于胚胎干细胞培养
公开(公告)号：US20120202286A1
公开(公告)日：2012-08-09
申请号：US13451268
申请日：2012-04-19
申请人： Jie Xu , Jerry Yang , Xiuchun Tian , Fuliang Du , Yinghong Ma
发明人： Jie Xu , Jerry Yang , Xiuchun Tian , Fuliang Du , Yinghong Ma
IPC分类号： C12N5/0735 , C12N5/02
CPC分类号： C07K14/5415 , C12N2501/235
摘要： Provided herein methods of maintaining an embryonic stem cell culture in an undifferentiated state, wherein the method includes culturing an embryonic stem cell on a rabbit feeder cell layer, wherein the rabbit feeder layer expresses a leukemia inhibitory factor (LIF) protein. Also provided are methods of maintaining an embryonic stem cell culture in an undifferentiated state, wherein the method includes culturing an embryonic stem cell in a culture medium comprising rabbit leukemia inhibitory factor (rbLIF) protein. Also provided are polynucleotide and amino acid sequences of a rabbit leukemia inhibitory factor protein (rbLIF).
摘要翻译：本发明提供将胚胎干细胞培养物维持在未分化状态的方法，其中所述方法包括在兔饲养细胞层上培养胚胎干细胞，其中所述兔饲养层表达白血病抑制因子（LIF）蛋白。还提供了将胚胎干细胞培养物维持在未分化状态的方法，其中所述方法包括在包含兔白血病抑制因子（rbLIF）蛋白的培养基中培养胚胎干细胞。还提供了兔白血病抑制因子蛋白（rbLIF）的多核苷酸和氨基酸序列。

4. 发明申请

US20070066665A1 Compounds and methods for the diagnosis and treatment of amyloid associated diseases 有权
标题翻译：用于诊断和治疗淀粉样蛋白相关疾病的化合物和方法
公开(公告)号：US20070066665A1
公开(公告)日：2007-03-22
申请号：US11487224
申请日：2006-07-14
申请人： Jerry Yang , Petra Inbar
发明人： Jerry Yang , Petra Inbar
IPC分类号： A61K31/428 , C07D417/02 , C12Q1/00
CPC分类号： G01N33/6896 , C07D417/10 , C07D417/12 , G01N2500/02 , G01N2800/2814
摘要： The invention is in general directed to compounds and methods for diagnosing, preventing or alleviating the symptoms of amyloid-associated diseases, for example, neuronal diseases, such as, for example, Alzheimer's disease, methods of screening for compounds useful in preventing or alleviating the symptoms of amyloid-associated diseases, methods of diagnostic imaging of A-beta fibrils, and compounds and methods useful for studying normal or disease-associated cellular mechanisms relating to amyloid proteins.
摘要翻译：本发明一般涉及用于诊断，预防或减轻淀粉样蛋白相关疾病的症状的化合物和方法，例如神经元疾病，例如阿尔茨海默氏病，筛选用于预防或减轻疾病的化合物的方法淀粉样蛋白相关疾病的症状，A-β原纤维的诊断成像方法，以及可用于研究与淀粉样蛋白相关的正常或疾病相关细胞机制的化合物和方法。

5. 发明申请

US20130157924A1 REDUCING TRANSMISSION OF SEXUALLY TRANSMITTED INFECTIONS 审中-公开
标题翻译：减少传染性传染性感染
公开(公告)号：US20130157924A1
公开(公告)日：2013-06-20
申请号：US13643026
申请日：2011-04-22
申请人： Stephen Dewhurst , Bradley Nilsson , Joanna Olsen , Jerry Yang
发明人： Stephen Dewhurst , Bradley Nilsson , Joanna Olsen , Jerry Yang
IPC分类号： A61K31/428 , A61K47/48 , A61K45/06
CPC分类号： A61K31/428 , A61K45/06 , A61K47/55 , A61K47/64
摘要： Described herein are compositions and methods for treating or preventing a sexually transmitted infection in a subject.
摘要翻译：本文描述了用于治疗或预防受试者中性传播感染的组合物和方法。

6. 发明申请

US20130048499A1 CONTROLLING TRANSLOCATION THROUGH NANOPORES WITH FLUID WALL 有权
标题翻译：通过流体管道通过纳米管控制转移
公开(公告)号：US20130048499A1
公开(公告)日：2013-02-28
申请号：US13400472
申请日：2012-02-20
申请人： Michael Mayer , Erik Yusko , Jerry Yang
发明人： Michael Mayer , Erik Yusko , Jerry Yang
IPC分类号： G01N27/26 , B82Y30/00
CPC分类号： G01N33/48721 , B82Y30/00 , C12Q1/6869 , G01N15/1209 , G01N2015/0038 , C12Q2563/131 , C12Q2565/631
摘要： Improved resolution and detection of nanoparticles are achieved when a nanopore connecting liquid compartments in a device running on the Coulter principle is provided with fluid lipid walls. The fluid lipid walls are made of a lipid bilayer, and preferably include lipid anchored mobile ligands as part of the lipid bilayer. By varying the nature and concentration of the mobile ligand in the lipid bilayer, multifunctional coatings of lipids are provided.
摘要翻译：当在Coulter原理上运行的装置中的纳米孔连接液体隔室设置有流体脂质壁时，实现了纳米颗粒的改进的分辨率和检测。流体脂质壁由脂质双层制成，优选包括脂质锚定的移动配体作为脂质双层的一部分。通过改变脂质双层中的移动配体的性质和浓度，提供脂质的多功能涂层。

7. 发明申请

US20110199041A1 RECHARGEABLE BATTERY PRODUCT 审中-公开
标题翻译：可充电电池产品
公开(公告)号：US20110199041A1
公开(公告)日：2011-08-18
申请号：US13030107
申请日：2011-02-17
申请人： JERRY YANG
发明人： JERRY YANG
IPC分类号： H01M10/46 , H02J7/00
CPC分类号： H01M10/46 , H01M10/465 , H01M10/488
摘要： A rechargeable battery product for a portable electronic device is disclosed. The case comprises a controller module detachably attached to a replaceable battery module. The battery module can be detached and charged from the controller module to provide continuous power to the device. The device can be powered simultaneously while recharging the battery module by connecting an external interface of the controller module with an external power source. The controller module further comprises an on/off switch that reduces the amount of power discharged from the battery when the portable electronic device is fully charged or when the battery is not in use and an indicator that indicates the remaining power of the battery module. The depleted battery module can be swapped with a new battery module to provide continuous power to the device for long time periods.
摘要翻译：公开了一种用于便携式电子设备的可充电电池产品。该情况包括可拆卸地附接到可更换电池模块的控制器模块。电池模块可以从控制器模块拆卸并充电，以向设备提供持续的电力。通过将控制器模块的外部接口与外部电源连接来对电池模块进行充电，可以同时为设备供电。控制器模块还包括开/关开关，当便携式电子设备完全充电时或当电池未使用时，减少从电池释放的电力的量，以及指示电池模块的剩余电力的指示器。耗尽的电池模块可以与新的电池模块交换，以便为设备提供长时间的连续电力。

8. 发明申请

US20110046020A1 NOVEL ION CHANNEL-FORMING PEPTIDES 有权
标题翻译：新型离子通道肽
公开(公告)号：US20110046020A1
公开(公告)日：2011-02-24
申请号：US12668178
申请日：2008-07-09
申请人： Jerry Yang , Steven Blake , Michael Mayer
发明人： Jerry Yang , Steven Blake , Michael Mayer
IPC分类号： C40B60/00 , C07K2/00 , C07K7/66 , C12Q1/42 , C12M1/34
CPC分类号： G01N33/5438
摘要： The invention pertains generally to novel compositions and methods for constructing chemically sensitive ion channels. The compositions and methods include, for example, novel gramicidin A derivatives and their use in constructing novel ion channels for use as biosensors.
摘要翻译：本发明一般涉及用于构建化学敏感离子通道的新型组合物和方法。组合物和方法包括例如新型短杆菌肽A衍生物及其在构建用作生物传感器的新型离子通道中的用途。

9. 发明授权

US07666886B2 Compounds and methods for the diagnosis and treatment of amyloid associated diseases 有权
标题翻译：用于诊断和治疗淀粉样蛋白相关疾病的化合物和方法
公开(公告)号：US07666886B2
公开(公告)日：2010-02-23
申请号：US11487224
申请日：2006-07-14
申请人： Jerry Yang , Petra Inbar
发明人： Jerry Yang , Petra Inbar
IPC分类号： A01N43/78 , A61K31/425 , C07D277/60 , C07D277/62
CPC分类号： G01N33/6896 , C07D417/10 , C07D417/12 , G01N2500/02 , G01N2800/2814
摘要： The invention is in general directed to compounds and methods for diagnosing, preventing or alleviating the symptoms of amyloid-associated diseases, for example, neuronal diseases, such as, for example, Alzheimer's disease, methods of screening for compounds useful in preventing or alleviating the symptoms of amyloid-associated diseases, methods of diagnostic imaging of A-beta fibrils, and compounds and methods useful for studying normal or disease-associated cellular mechanisms relating to amyloid proteins.
摘要翻译：本发明一般涉及用于诊断，预防或减轻淀粉样蛋白相关疾病的症状的化合物和方法，例如神经元疾病，例如阿尔茨海默氏病，筛选用于预防或减轻疾病的化合物的方法淀粉样蛋白相关疾病的症状，A-β原纤维的诊断成像方法，以及可用于研究与淀粉样蛋白相关的正常或疾病相关细胞机制的化合物和方法。

10. 发明授权

US08575359B2 Acid-sensitive linkers for drug delivery 有权
标题翻译：用于药物输送的酸敏感接头
公开(公告)号：US08575359B2
公开(公告)日：2013-11-05
申请号：US12295858
申请日：2007-04-04
申请人： Jerry Yang , Seong Deok Kong , Alice Luong , Stephen Howell
发明人： Jerry Yang , Seong Deok Kong , Alice Luong , Stephen Howell
IPC分类号： C07D233/00 , C07D233/02 , C07D233/54 , C07D233/60 , C07H15/24
CPC分类号： C07D233/68 , C07D233/60
摘要： The invention is in general directed to acid-sensitive linkers, and methods of use thereof, such as, for example, in drug delivery methods.
摘要翻译：本发明一般涉及酸敏感连接体及其使用方法，例如药物递送方法。

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