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1. 外观设计

USD731112S1 Electronic cigarette 有权
公开(公告)号：USD731112S1
公开(公告)日：2015-06-02
申请号：US29472592
申请日：2013-11-14
申请人： Jianwei Li
设计人： Jianwei Li

2. 发明授权

US08173622B2 Antimicrobial compounds having protective or therapeutic leaving groups 有权
标题翻译：具有保护性或治疗性离去基团的抗微生物化合物
公开(公告)号：US08173622B2
公开(公告)日：2012-05-08
申请号：US12192268
申请日：2008-08-15
申请人： Paul Hsien-Fu Wu , Catherine E. Taylor , Linnus Cheruiyot , Jianwei Li , Terese A. Bartlett , Matt Bergan
发明人： Paul Hsien-Fu Wu , Catherine E. Taylor , Linnus Cheruiyot , Jianwei Li , Terese A. Bartlett , Matt Bergan
IPC分类号： A01N55/00
CPC分类号： A61L27/54 , A61K31/575 , A61K31/695 , A61K47/6957 , A61L27/443 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/216 , A61L2300/222 , A61L2300/404 , A61L2300/41 , A61L2300/416 , C07F7/1804
摘要： Antimicrobial compounds, such as silanol or alcohol, include a protecting or leaving group that can protect the compound from degradation during the process of preparing a medical device containing the compound or reduce the volatility of the compound relative to its counterpart without the leaving group. Nearly any hydrolysable leaving group may be employed. The leaving group may be an agent that may serve a therapeutic function in addition to protecting or retaining the antimicrobial agents.
摘要翻译：抗微生物化合物，例如硅烷醇或醇，包括保护或离去基团，其可以在制备含有化合物的医疗装置的过程中保护化合物免于降解，或降低化合物相对于其对应物的挥发性而不用离去基团。可以使用几乎任何可水解的离去基团。除了保护或保留抗微生物剂之外，离去基团可以是可以起到治疗功能的药剂。

3. 发明申请

US20090047321A1 ANTIMICROBIAL COMPOUNDS HAVING PROTECTIVE OR THERAPEUTIC LEAVING GROUPS 有权
标题翻译：具有保护性或治疗性组合的抗微生物化合物
公开(公告)号：US20090047321A1
公开(公告)日：2009-02-19
申请号：US12192268
申请日：2008-08-15
申请人： Paul Hsien-Fu Wu , Catherine E. Taylor , Linnus Cheruiyot , Jianwei Li , Terese A. Bartlett , Matt Bergan
发明人： Paul Hsien-Fu Wu , Catherine E. Taylor , Linnus Cheruiyot , Jianwei Li , Terese A. Bartlett , Matt Bergan
IPC分类号： A61K31/695 , A61K31/575 , A61P31/00 , A61K9/00 , C07F7/08
CPC分类号： A61L27/54 , A61K31/575 , A61K31/695 , A61K47/6957 , A61L27/443 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/216 , A61L2300/222 , A61L2300/404 , A61L2300/41 , A61L2300/416 , C07F7/1804
摘要： Antimicrobial compounds, such as silanol or alcohol, include a protecting or leaving group that can protect the compound from degradation during the process of preparing a medical device containing the compound or reduce the volatility of the compound relative to its counterpart without the leaving group. Nearly any hydrolysable leaving group may be employed. The leaving group may be an agent that may serve a therapeutic function in addition to protecting or retaining the antimicrobial agents.
摘要翻译：抗微生物化合物，例如硅烷醇或醇，包括保护或离去基团，其可以在制备含有化合物的医疗装置的过程中保护化合物免于降解，或降低化合物相对于其对应物的挥发性而不用离去基团。可以使用几乎任何可水解的离去基团。除了保护或保留抗微生物剂之外，离去基团可以是可以起到治疗功能的药剂。

4. 外观设计

USD756559S1 Electronic cigarette 有权
公开(公告)号：USD756559S1
公开(公告)日：2016-05-17
申请号：US29477221
申请日：2013-12-20
申请人： Jianwei Li
设计人： Jianwei Li

5. 外观设计

USD727562S1 Electronic cigarette 有权
公开(公告)号：USD727562S1
公开(公告)日：2015-04-21
申请号：US29466713
申请日：2013-09-11
申请人： Jianwei Li
设计人： Jianwei Li

6. 发明申请

US20120088713A1 TNF INHIBITOR FORMULATION FOR USE IN IMPLANTABLE INFUSION DEVICES 有权
标题翻译：用于可浸润输注装置的TNF抑制剂配方
公开(公告)号：US20120088713A1
公开(公告)日：2012-04-12
申请号：US13252745
申请日：2011-10-04
申请人： Deanna S. Lane , Charlene X. Yuan , Jianwei Li , Lanchi T. Le
发明人： Deanna S. Lane , Charlene X. Yuan , Jianwei Li , Lanchi T. Le
IPC分类号： A61K38/00 , A61P35/00
CPC分类号： A61K9/0019 , A61K47/26
摘要： A formulation for use in an implantable infusion device includes between about 5 mg/ml and about 500 mg/ml (e.g., about 10-25 mg/ml) of a TNF inhibitor polypeptide, 10 mM-25 mM of a phosphate or citrate buffer, has an ionic strength of the combined buffer and an optional salt of the equivalent of about 0.1-0.2 NaCl (e.g., about 0.15 M), 5% to 10% of a carbohydrate (e.g., trehalose or sucrose), has a pH of between 6 and 7, is fluid at room temperature and at 37° C., and has a viscosity of less than about 10 centipoise (e.g., between about 1 centipoise and 9 centipoise, between about 1 cp and about 5 cp, between about 1 cp and about 3 cp, or between about 1 cp and about 2.5 cp) at room temperature.
摘要翻译：用于可植入输注装置的制剂包括约5mg / ml至约500mg / ml（例如约10-25mg / ml）的TNF抑制剂多肽，10mM -25mM磷酸盐或柠檬酸盐缓冲液具有组合缓冲液的离子强度和等同于约0.1-0.2NaCl（例如约0.15M），5％至10％的碳水化合物（例如海藻糖或蔗糖）的任选的盐的pH为在6和7之间，在室温和37℃下是流体，并且具有小于约10厘泊的粘度（例如，在约1厘泊和9厘泊之间，约1cp和约5cp之间，约1 cp和约3cp，或约1cp至约2.5cp）。

7. 发明申请

US20180372241A1 PRESS FIT VALVE ADAPTATION FOR TOP ENTRY VALVE IN CRYOGENIC SERVICE 审中-公开
公开(公告)号：US20180372241A1
公开(公告)日：2018-12-27
申请号：US15775282
申请日：2015-11-10
申请人： Alain BRIGLIA , Jianwei LI , L'Air Liquide, Societe Anonyme pour l'Etude et l'Exploitation des Procedes Georges Claude
发明人： Alain BRIGLIA , Jianwei LI
IPC分类号： F16K43/00 , F17C13/04 , F16K27/02
摘要： A press-fit in situ retrofit assembly for a top entry valve and a method thereof are disclosed. The assembly includes an annular conduit (201) including a segment (202) of reduced outside diameter and a shoulder (203) on the exterior surface at the proximal end (204), and is configured to conform with an interior surface (205) of a valve seat (206) at the distal end (207). A valve body extension (208) with an interior annular region (301), and an inlet port (209) fluidically connected to the annular region (301). A gland packing push plate (211) is configured to allow the annular conduit (201) to pass through thereby forming an outlet port (212). And a thrust plate (403) is attached to the thrust screws (401). The thrust plate (403) allows the segment (202) of reduced outside diameter at the proximal end (204) of the annular conduit (201) to pass through, with the thrust plate (403) seating on the shoulder (203). The assembly and the method allow the removal of a portion of the fluid from the cold box for downstream processing or manipulation as desired.

8. 发明授权

US09445990B2 TNF inhibitor formulation for use in implantable infusion devices 有权
标题翻译：用于可植入输注装置的TNF抑制剂制剂
公开(公告)号：US09445990B2
公开(公告)日：2016-09-20
申请号：US13252745
申请日：2011-10-04
申请人： Deanna S. Lane , Charlene X. Yuan , Jianwei Li , Lanchi T. Le
发明人： Deanna S. Lane , Charlene X. Yuan , Jianwei Li , Lanchi T. Le
IPC分类号： A61K9/00 , A61K47/26 , A61K38/00 , A61K38/19
CPC分类号： A61K9/0019 , A61K47/26
摘要： A formulation for use in an implantable infusion device includes between about 5 mg/ml and about 500 mg/ml (e.g., about 10-25 mg/ml) of a TNF inhibitor polypeptide, 10 mM-25 mM of a phosphate or citrate buffer, has an ionic strength of the combined buffer and an optional salt of the equivalent of about 0.1-0.2 NaCl (e.g., about 0.15 M), 5% to 10% of a carbohydrate (e.g., trehalose or sucrose), has a pH of between 6 and 7, is fluid at room temperature and at 37° C., and has a viscosity of less than about 10 centipoise (e.g., between about 1 centipoise and 9 centipoise, between about 1 cp and about 5 cp, between about 1 cp and about 3 cp, or between about 1 cp and about 2.5 cp) at room temperature.
摘要翻译：用于可植入输注装置的制剂包括约5mg / ml至约500mg / ml（例如约10-25mg / ml）的TNF抑制剂多肽，10mM -25mM磷酸盐或柠檬酸盐缓冲液具有组合缓冲液的离子强度和等同于约0.1-0.2NaCl（例如约0.15M），5％至10％的碳水化合物（例如海藻糖或蔗糖）的任选的盐的pH为在6和7之间，在室温和37℃下是流体，并且具有小于约10厘泊的粘度（例如，在约1厘泊和9厘泊之间，约1cp和约5cp之间，约1 cp和约3cp，或约1cp至约2.5cp）。

9. 外观设计

USD727563S1 Electronic cigarette 有权
公开(公告)号：USD727563S1
公开(公告)日：2015-04-21
申请号：US29472593
申请日：2013-11-14
申请人： Jianwei Li
设计人： Jianwei Li

10. 发明申请

US20150020829A1 Electronic cigarette vaporizer with separable components 审中-公开
标题翻译：具有可分离组件的电子烟雾蒸发器
公开(公告)号：US20150020829A1
公开(公告)日：2015-01-22
申请号：US14103847
申请日：2013-12-12
申请人： JIANWEI LI
发明人： JIANWEI LI
IPC分类号： A24F47/00
CPC分类号： A24F47/008
摘要： An electronic cigarette vaporizer with separable components comprising a liquid storage device and a high-temperature vaporizer; the liquid storage device comprises a main body and a top cover; the main body an open end; the top cover sleeves on the open end of the main body; the top cover and the main body are connected and sealed; a gas suction tube is disposed inside the main body; the high-temperature vaporizer comprises a sleeve, conductors sleeved inside the sleeve, a supporting frame and a heating wire; electronic cigarette oil openings are disposed on the supporting frame; one end of each of the conductors is connected with a respective electronic cigarette oil opening; a heating portion of the heating wire is disposed at a gas suction hole; two ends of the heating wire are connected with an anode and a cathode of a power supply respectively.
摘要翻译：一种具有可分离组件的电子烟雾蒸发器，包括液体储存装置和高温蒸发器; 液体储存装置包括主体和顶盖; 主体开放; 主体开口端的顶盖套筒; 顶盖和主体连接并密封; 吸气管设置在主体内部; 高温蒸发器包括套筒，套筒套管内的导体，支撑框架和加热丝线; 电子香烟油开口设置在支撑架上; 每个导体的一端与相应的电子香烟油开口连接; 加热线的加热部分设置在气体吸入孔处; 电热丝的两端分别与电源的阳极和阴极连接。

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