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    • 1. 发明授权
    • System for reconstitution of a powdered drug
    • 重组粉末药物的制度
    • US08790328B2
    • 2014-07-29
    • US13123685
    • 2009-10-15
    • Lasse KragelundJohn Thrane Hansen
    • Lasse KragelundJohn Thrane Hansen
    • A61J1/14
    • A61J1/2089A61J1/201A61J1/2013A61J1/2037A61J1/2062A61J1/2075A61J1/2096A61M5/162A61M2039/0027
    • A mixing system (1) adapted to allow first contents of a first container (2) and second contents of a second container (3) to mix to form a material. The mixed material is retrieved to a syringe (20) without being foamed. The mixing system (1) comprises a transfer unit (5) which is adapted to receive the first container (2) at a first port (11), the second container (3) at a second port (12) and the syringe (20) at a third port (13). The transfer unit (5) further houses a number of fluid pathways (14, 15, 16) interconnecting the three ports (11, 12, 13) as well as a number of flow control members (17, 18, 19, 22) for controlling fluid flow between the containers (2, 3) and the syringe (20). At least one of the flow control members (17, 18, 19, 22) allows a user to switch between two states of fluid flow, one in which fluid flow is enabled between the first port (11) and the third port (13) as well as between the third port (13) and the second port (12), and one in which fluid flow is enabled between the second port (12) and the third port (13). The invention also relates to a transfer unit comprising first and second ports for receiving first and second containers, respectively, a third port for coupling to a syringe, a number of fluid pathways interconnecting the ports, at least one flow control member which allows a user to switch between two states of fluid flow, and a locking means to ensure that the at least one flow control member can only be manipulated when a syringe is coupled to the third port.
    • 一种适于允许第一容器(2)的第一内容物和第二容器(3)的第二内容物混合以形成材料的混合系统(1)。 将混合的材料回收到注射器(20)而不发泡。 混合系统(1)包括转移单元(5),其适于在第一端口(11)处容纳第一容器(2),第二容器(3)在第二端口(12)和注射器(20) )在第三端口(13)。 传送单元(5)还容纳多个互连三个端口(11,12,13)的流体路径(14,15,16)以及多个流量控制构件(17,18,19,22),用于 控制容器(2,3)和注射器(20)之间的流体流动。 至少一个流量控制构件(17,18,19,22)允许使用者在两个流体流动状态之间切换,其中流体流在第一端口(11)和第三端口(13)之间启用, 以及在第三端口(13)和第二端口(12)之间以及在第二端口(12)和第三端口(13)之间能够进行流体流动的端口。 本发明还涉及一种转移单元,其包括用于分别接收第一和第二容器的第一和第二端口,用于连接到注射器的第三端口,将端口互连的多个流体通路,允许使用者的至少一个流量控制构件 以在两种流体流动状态之间切换,以及锁定装置,以确保只有当注射器联接到第三端口时,才能操纵至少一个流量控制构件。
    • 2. 发明申请
    • SYSTEM FOR RECONSTITUTION OF A POWDERED DRUG
    • 用于重配药物的系统
    • US20120029464A1
    • 2012-02-02
    • US13123685
    • 2009-10-15
    • Lasse KragelundJohn Thrane Hansen
    • Lasse KragelundJohn Thrane Hansen
    • A61J1/14
    • A61J1/2089A61J1/201A61J1/2013A61J1/2037A61J1/2062A61J1/2075A61J1/2096A61M5/162A61M2039/0027
    • A mixing system (1) adapted to allow first contents of a first container (2) and second contents of a second container (3) to mix to form a material. The mixed material is retrieved to a syringe (20) without being foamed. The mixing system (1) comprises a transfer unit (5) which is adapted to receive the first container (2) at a first port (11), the second container (3) at a second port (12) and the syringe (20) at a third port (13). The transfer unit (5) further houses a number of fluid pathways (14, 15, 16) interconnecting the three ports (11, 12, 13) as well as a number of flow control members (17, 18, 19, 22) for controlling fluid flow between the containers (2, 3) and the syringe (20). At least one of the flow control members (17, 18, 19, 22) allows a user to switch between two states of fluid flow, one in which fluid flow is enabled between the first port (11) and the third port (13) as well as between the third port (13) and the second port (12), and one in which fluid flow is enabled between the second port (12) and the third port (13). The invention also relates to a transfer unit comprising first and second ports for receiving first and second containers, respectively, a third port for coupling to a syringe, a number of fluid pathways interconnecting the ports, at least one flow control member which allows a user to switch between two states of fluid flow, and a locking means to ensure that the at least one flow control member can only be manipulated when a syringe is coupled to the third port.
    • 一种适于允许第一容器(2)的第一内容物和第二容器(3)的第二内容物混合以形成材料的混合系统(1)。 将混合的材料回收到注射器(20)而不发泡。 混合系统(1)包括转移单元(5),其适于在第一端口(11)处容纳第一容器(2),第二容器(3)在第二端口(12)和注射器(20) )在第三端口(13)。 传送单元(5)还容纳多个互连三个端口(11,12,13)的流体路径(14,15,16)以及多个流量控制构件(17,18,19,22),用于 控制容器(2,3)和注射器(20)之间的流体流动。 至少一个流量控制构件(17,18,19,22)允许使用者在两个流体流动状态之间切换,其中流体流在第一端口(11)和第三端口(13)之间启用, 以及在第三端口(13)和第二端口(12)之间以及在第二端口(12)和第三端口(13)之间能够进行流体流动的端口。 本发明还涉及一种转移单元,其包括用于分别接收第一和第二容器的第一和第二端口,用于连接到注射器的第三端口,将端口互连的多个流体通路,允许使用者的至少一个流量控制构件 以在两种流体流动状态之间切换,以及锁定装置,以确保只有当注射器联接到第三端口时,才能操纵至少一个流量控制构件。
    • 3. 发明授权
    • Dose setting device
    • 剂量设定装置
    • US06796970B1
    • 2004-09-28
    • US09090144
    • 1998-06-04
    • Lars Peter KlitmoseHenrik AndersenPreben Broskov NielsenJohn Thrane Hansen
    • Lars Peter KlitmoseHenrik AndersenPreben Broskov NielsenJohn Thrane Hansen
    • A61M500
    • A61M5/315A61M5/24A61M5/3146A61M5/31511A61M5/31525A61M5/31543A61M5/31553A61M5/31556A61M5/31558A61M5/31563A61M5/31571A61M5/31575A61M5/3158A61M5/31593A61M5/31595A61M2005/14573A61M2005/31518B05C17/0113Y10S128/01
    • A dose setting device for a delivery system has a piston rod (6, 9) which successively presses a piston (2) into a cylinder ampoule (1). Doses are set by rotating a second part (9) of the piston rod (6, 9) in relation to a first part (6). The two parts are connected by mating threads so that the total length of the piston rod (6, 9) is increased proportional to the angle of rotation, and a point (18) on the second part is moved away from a stop position fixed in relation to a housing (5) The set dose is delivered when the point (18) is moved back to the stop position. The first part (6) can be axially displaced but not rotated in the housing (5), and the second part (9) can both rotate and be axially displaced. The first part (6) is maintained in abutment with the piston (2) and the second part (9) is coupled to be rotated by a dose setting wheel (20). An injection push button (10) is movable between a projecting position and a pressed home position and has elements (13) acting on the second part (9) to press this part to its stop position.
    • 用于输送系统的剂量设定装置具有连续地将活塞(2)压入气缸安瓿(1)中的活塞杆(6,9)。 通过相对于第一部分(6)旋转活塞杆(6,9)的第二部分(9)来设定剂量。 两个部件通过配合螺纹连接,使得活塞杆(6,9)的总长度与旋转角成比例地增加,并且第二部件上的点(18)移动离开固定在 与外壳的关系(5)当点(18)移回到停止位置时,传送设定的剂量。 第一部分(6)可以在壳体(5)中轴向移位但不旋转,并且第二部分(9)都可以旋转并且被轴向移位。 第一部分(6)保持与活塞(2)邻接,并且第二部分(9)被联接以由剂量设定轮(20)旋转。 注射按钮(10)能够在突出位置和被按压的原始位置之间移动,并且具有作用在第二部分(9)上的元件(13)以将该部分按压到其停止位置。
    • 4. 发明申请
    • Device For Displaying Data Relevant For a Diabetic Patient
    • 显示与糖尿病患者有关的数据的设备
    • US20090048565A1
    • 2009-02-19
    • US11792645
    • 2005-12-07
    • John Thrane Hansen
    • John Thrane Hansen
    • A61M5/31
    • G06F19/3481G16H40/63
    • This invention relates to a device with a display (8) for displaying graphics, text and/or combinations thereof, the device has a processor (230) that is interfaced with said display, where the processor can compute and cause the display to display when to administer bolus insulin in which dose(s), when insulin at several occasions in fact were administered and in which doses at these occasions. Moreover, the processor can compute data linking a treatment regimen and insulin administered in the past. A display of the relations between the treatment regimen and the insulin administered in the past are possible. Moreover, a display of data, e.g. a graph, showing insulin administered in the past for longer periods, e.g. more days, months, etc. is possible. The data is useful in a dialogue between a health care person and a diabetic patient.
    • 本发明涉及具有用于显示图形,文本和/或其组合的显示器(8)的设备,该设备具有与所述显示器接口的处理器(230),其中处理器可以计算并使显示器何时显示 施用其中剂量的推注胰岛素,其中实际上多次施用胰岛素并且在这些情况下以其剂量施用。 此外,处理器可以计算连接治疗方案和过去施用的胰岛素的数据。 治疗方案与过去给予的胰岛素之间的关系的展示是可能的。 此外,显示数据,例如。 显示了过去长时间给予胰岛素的图表。 更多的日子,月份等是可能的。 数据在保健人员和糖尿病患者之间的对话中是有用的。