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1. 发明申请

US20070212778A1 Cell culture medium 审中-公开
标题翻译：细胞培养基
公开(公告)号：US20070212778A1
公开(公告)日：2007-09-13
申请号：US11705599
申请日：2007-02-13
申请人： Irene Bramke , Julian Burke
发明人： Irene Bramke , Julian Burke
IPC分类号： C12N5/06
CPC分类号： C12N5/0018 , C12N2500/40 , C12N2500/95 , C12N2533/78
摘要： We describe a method of growing an animal cell in a culture medium, in which the culture medium comprises an elevated concentration of a thymidine family member, in which the growth or viability of the animal cell is increased as a result of the elevated concentration of the thymidine family member in the cell culture medium. Preferably, the cell culture medium comprises a semi-solid medium, which is a serum free or chemically defined medium.
摘要翻译：我们描述了在培养基中培养动物细胞的方法，其中培养基包含升高浓度的胸苷家族成员，其中动物细胞的生长或活力由于浓度的升高而增加胸腺嘧啶家族成员在细胞培养基中。优选地，细胞培养基包含半固体培养基，其为无血清或化学成分确定的培养基。

2. 发明授权

US09333913B1 Real time vehicle safety alert system 有权
标题翻译：实时车辆安全警戒系统
公开(公告)号：US09333913B1
公开(公告)日：2016-05-10
申请号：US14846028
申请日：2015-09-04
申请人： Steven D. Elders , Alex Julian Burke
发明人： Steven D. Elders , Alex Julian Burke
IPC分类号： B60Q1/00 , B60Q9/00 , G08G1/00 , H04H20/00
CPC分类号： B60Q9/008 , B60K35/00 , B60K2350/357 , B60Q9/00 , G08B25/016 , G08G1/00 , G08G1/0965 , G08G1/162 , G08G1/205 , H04H20/00
摘要： A real time vehicle safety alert system for monitoring and alerting of hazards proximate a traveling vehicle includes an alert module in data communication with a processor and memory. The alert module may be positioned in a vehicle and in data communication with the vehicle's computer. A global position system is in communication with the processor for determining a current global position associated with the alert module. A receiver is in data communication with the processor and configured to receive alert signals from remote sources. The processor causes the receiver to receive an alert signal and to determine the type of emergency and a global position associated with the received signal. If the alert signal is within a predetermined distance of the position of the alert module, an associated alert message is published to the alert module. If the vehicle computer senses an emergency, a transmitter transmits an alert message.
摘要翻译：用于监测和警报靠近行驶车辆的危险的实时车辆安全警报系统包括与处理器和存储器进行数据通信的报警模块。警报模块可以被定位在车辆中并且与车辆的计算机进行数据通信。全球定位系统与处理器通信以确定与警报模块相关联的当前全球位置。接收机与处理器进行数据通信，并配置为从远程源接收警报信号。处理器使得接收机接收警报信号并且确定与接收信号相关联的紧急类型和全局位置。如果警报信号在警报模块的位置的预定距离内，则向警报模块发布关联的警报消息。如果车辆计算机感测到紧急情况，则发射机发送警报消息。

3. 发明授权

US06597500B1 Adhesive label with grid for microscope slide 失效
标题翻译：粘贴标签带网格显微镜载玻片
公开(公告)号：US06597500B1
公开(公告)日：2003-07-22
申请号：US09717070
申请日：2000-11-22
申请人： Julian Burke , Nishith Patel
发明人： Julian Burke , Nishith Patel
IPC分类号： G02B2101
CPC分类号： G09F3/10 , B01J2219/00527 , B01J2219/00529 , B01J2219/00533 , B01J2219/0054 , B01J2219/00542 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/00612 , B01J2219/00659 , C40B70/00 , G02B21/34
摘要： An adhesive label 3 for attaching to a microscope slide 1 is disclosed. The label 3 may have one or more grids or arrays 2 provided on it to help an operator to manually spot a microscope slide 1.
摘要翻译：公开了一种用于附接到显微镜载玻片1的粘合标签3。标签3可以具有设置在其上的一个或多个栅格或阵列2，以帮助操作者手动地点一个显微镜载玻片1。

4. 发明授权

US08497138B2 Method for cell selection 有权
标题翻译：细胞选择方法
公开(公告)号：US08497138B2
公开(公告)日：2013-07-30
申请号：US12895273
申请日：2010-09-30
申请人： Julian Burke , Alasdair Robertson , Xiao Zhang
发明人： Julian Burke , Alasdair Robertson , Xiao Zhang
IPC分类号： G01N33/53 , G01N33/00
CPC分类号： G01N33/5044
摘要： In one aspect the present invention provides a method for selecting a cell or cell colony which produces a polypeptide of interest, comprising a) providing a medium comprising cells and a detection agent, wherein the detection agent is associated with a detectable signal and the detection agent is capable of binding to the polypeptide of interest; b) providing a solid phase having a capture agent disposed thereon, wherein the capture agent is capable of binding to the polypeptide of interest; c) contacting the medium with the solid phase; d) detecting the signal associated with the detection agent; and e) selecting a cell or cell colony associated with the signal, wherein presence of the signal is indicative of a cell or cell colony which produces the polypeptide of interest.
摘要翻译：在一个方面，本发明提供了选择产生感兴趣多肽的细胞或细胞集落的方法，其包括a）提供包含细胞和检测剂的培养基，其中所述检测剂与可检测信号相关联，并且所述检测剂能够结合目的多肽; b）提供其上设置有捕获剂的固相，其中捕获剂能够结合感兴趣的多肽; c）使介质与固相接触; d）检测与检测剂相关的信号; 和e）选择与所述信号相关的细胞或细胞集落，其中所述信号的存在指示产生感兴趣多肽的细胞或细胞集落。

5. 发明申请

US20120082361A1 METHOD 有权
标题翻译：方法
公开(公告)号：US20120082361A1
公开(公告)日：2012-04-05
申请号：US12895273
申请日：2010-09-30
申请人： Julian BURKE , Alasdair ROBERTSON , Xiao ZHANG
发明人： Julian BURKE , Alasdair ROBERTSON , Xiao ZHANG
IPC分类号： G06K9/00 , C12M1/34 , G01N33/68
CPC分类号： G01N33/5044
摘要： In one aspect the present invention provides a method for selecting a cell or cell colony which produces a polypeptide of interest, comprising a) providing a medium comprising cells and a detection agent, wherein the detection agent is associated with a detectable signal and the detection agent is capable of binding to the polypeptide of interest; b) providing a solid phase having a capture agent disposed thereon, wherein the capture agent is capable of binding to the polypeptide of interest; c) contacting the medium with the solid phase; d) detecting the signal associated with the detection agent; and e) selecting a cell or cell colony associated with the signal, wherein presence of the signal is indicative of a cell or cell colony which produces the polypeptide of interest.
摘要翻译：在一个方面，本发明提供了选择产生感兴趣多肽的细胞或细胞集落的方法，其包括a）提供包含细胞和检测剂的培养基，其中所述检测剂与可检测信号相关联，并且所述检测剂能够结合目的多肽; b）提供其上设置有捕获剂的固相，其中捕获剂能够结合感兴趣的多肽; c）使介质与固相接触; d）检测与检测剂相关的信号; 和e）选择与所述信号相关的细胞或细胞集落，其中所述信号的存在指示产生感兴趣多肽的细胞或细胞集落。

6. 发明授权

US06308750B1 Microarrayer apparatus 失效
标题翻译：微阵列器
公开(公告)号：US06308750B1
公开(公告)日：2001-10-30
申请号：US09541078
申请日：2000-03-31
申请人： Julian Burke
发明人： Julian Burke
IPC分类号： B65B4342
CPC分类号： B01L99/00 , B01J19/0046 , B01J2219/00387 , B01J2219/00527 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00659 , B01J2219/00693 , B01L3/0293 , B01L9/50 , C40B60/14 , G01N35/028 , G02B25/002
摘要： A manual microarrayer apparatus is disclosed which includes an integral visual magnification system alphanumeric counter and LED display for tracking samples in a microtitre plate. The apparatus is preferably reversible so as to provide left and right handed user formats.
摘要翻译：公开了一种手动微阵列设备，其包括用于跟踪微量滴定板中的样品的整体视觉放大系统字母数字计数器和LED显示器。该装置优选是可逆的，以便提供左手和右手的用户格式。

7. 发明申请

US20070037220A1 Biomolecule specificity detection and selection method and apparatus 审中-公开
标题翻译：生物分子特异性检测及选择方法及装置
公开(公告)号：US20070037220A1
公开(公告)日：2007-02-15
申请号：US11199243
申请日：2005-08-09
申请人： Julian Burke , Christopher Mann
发明人： Julian Burke , Christopher Mann
IPC分类号： G01N33/567
CPC分类号： G01N33/6854 , G01N33/6857
摘要： We disclose a method of detecting a polypeptide of interest produced by a cell or a cell colony, the method comprising: (a) exposing the polypeptide to a class marker capable of identifying a class of polypeptides to which the polypeptide of interest belongs; (b) exposing the polypeptide to a specificity marker capable of identifying a specific binding ability of the polypeptide of interest; and (c) detecting binding of the polypeptide to the class marker or the specificity marker or both.
摘要翻译：我们公开了一种检测由细胞或细胞集落产生的感兴趣的多肽的方法，所述方法包括：（a）将多肽暴露于能够鉴定感兴趣的多肽的一类多肽的类标记; （b）将多肽暴露于能够鉴定感兴趣的多肽的特异性结合能力的特异性标记; 和（c）检测多肽与类别标记或特异性标记或两者的结合。

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