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1. 发明专利

JP2005287400A Diagnostic marker for hepatitis/hepatocirrhosis and hepatoma 审中-公开
标题翻译： HEPATITIS / HEPATOCIRRHOSIS和HEPATOMA诊断标记
公开(公告)号：JP2005287400A
公开(公告)日：2005-10-20
申请号：JP2004107259
申请日：2004-03-31
申请人： Nobuo Kondo , Scimedia Ltd , Mikio Yamamoto , Naoki Yamamoto , 三毅夫山本 , 直樹山本 , 株式会社サイメディア , 信夫近藤
发明人： KONDO NOBUO , YAMAMOTO NAOKI , YAMAMOTO MIKIO , WAKATSUKI TORU
IPC分类号： G01N33/53 , C12M1/00 , C12N15/09 , C12Q1/68 , G01N33/576 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide a molecular biological method for detecting human hepatitis/hepatocirrhosis and hepatoma.
SOLUTION: The method for detecting the hepatitis/hepatocirrhosis and hepatoma includes measuring a level of at least one of mRNA selected from the group consisting of SLC7A2 (CAT2, solution carrier family) and galectin 1 with respect to a liver tissue obtained from an examinee. Thus, diagnosis of the hepatitis/hepatocirrhosis and hepatoma based on a molecular biological procedure and diagnosis of malignancy thereof are carried out. Further, the diagnosis is objectively given with high accuracy, by avoiding an error caused by proficiency and subjective judgement of a physician giving the diagnosis, because the diagnosis is given based on the molecular biological procedure.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供用于检测人肝炎/肝硬化和肝癌的分子生物学方法。解决方案：用于检测肝炎/肝硬化和肝癌的方法包括相对于从肝脏组织获得的肝组织，测量选自SLC7A2（CAT2，溶液载体家族）和半乳凝素1中的至少一种mRNA的水平一名考生因此，进行基于分子生物学过程和恶性肿瘤诊断的肝炎/肝硬化和肝癌的诊断。此外，由于诊断是基于分子生物学过程给出的，因此通过避免给出诊断的医师的熟练程度和主观判断引起的错误，以高精度客观地给出诊断。版权所有（C）2006，JPO＆NCIPI

2. 发明授权

US08528357B2 Ice-making machine with ice storage bin 有权
标题翻译：制冰机与储冰箱
公开(公告)号：US08528357B2
公开(公告)日：2013-09-10
申请号：US12935745
申请日：2009-03-19
申请人： Nobuo Kondo , Kiyoshi Yamaoka , Hideyuki Tashiro , Takeshi Ueda , Takashi Hibino , Akira Harata
发明人： Nobuo Kondo , Kiyoshi Yamaoka , Hideyuki Tashiro , Takeshi Ueda , Takashi Hibino , Akira Harata
IPC分类号： F25D19/00 , F25D25/00 , F25D17/04 , F25D11/00 , F25C5/18
CPC分类号： F25D23/003 , F25C5/20 , F25D2323/00264 , F25D2323/00274 , F25D2323/00277
摘要： An ice-making machine has a box-shaped lower housing with an ice storage bin, a box-shaped upper housing mounted on a rear portion of the lower housing, an ice-making mechanism within the front portion of a machine compartment in the upper housing, and a freezing unit installed behind the ice-making mechanism for supplying refrigerant to the ice-making mechanism. An open-and-close ice-access lid is pivotally mounted between the lower end of the upper housing and the the lower housing. An air intake passage introduces outside cooling air from the front face of the lower housing into the machine compartment along inner surfaces of one side wall and a rear wall of the lower housing. An air discharge passage is provided for passing the air after cooling to flow outward along inner surfaces of the rear wall and the other side wall of the lower housing to an exterior discharge from the front face of the lower housing.
摘要翻译：制冰机具有带有储冰箱的盒形下壳体，安装在下壳体的后部上的盒形上壳体，在上部机器室前部的制冰机构壳体和安装在制冰机构后面的冷冻装置，用于向制冰机构供应制冷剂。一个开闭的导冰盖枢转地安装在上壳体的下端和下壳体之间。进气通道将外部冷却空气从下壳体的前表面引入机舱，其内侧面是下壳体的一个侧壁和后壁。设置有空气排出通道，用于使冷却后的空气在下壳体的后壁和另一侧壁的内表面向外流动，从而从下壳体的前表面向外排出。

3. 发明申请

US20100063124A1 NEW PYRAZOLE DERIVATIVES AND DIABETIC MEDICINE CONTAINING THEM 审中-公开
标题翻译：新型吡咯衍生物和含有他们的糖尿病药物
公开(公告)号：US20100063124A1
公开(公告)日：2010-03-11
申请号：US12621626
申请日：2009-11-19
申请人： Koji Ohsumi , Takashi Umemura , Hiroyuki Matsueda , Toshihiro Hatanaka , Akiko Onuki , Katsumi Maezono , Yoko Kageyama , Nobuo Kondo
发明人： Koji Ohsumi , Takashi Umemura , Hiroyuki Matsueda , Toshihiro Hatanaka , Akiko Onuki , Katsumi Maezono , Yoko Kageyama , Nobuo Kondo
IPC分类号： A61K31/4155 , C07D231/18 , A61P3/10
CPC分类号： A61K31/7056 , C07H17/02 , Y10S514/866
摘要： The present invention provides pyrazole-O-glycoside derivatives represented by the following formulae, used as a diabetic medicine.
摘要翻译：本发明提供用作糖尿病药的由下式表示的吡唑-O-糖苷衍生物。

4. 发明申请

US20070099979A1 NEW PYRAZOLE DERIVATIVES AND DIABETIC MEDICINE CONTAINING THEM 失效
标题翻译：新型吡咯衍生物和含有他们的糖尿病药物
公开(公告)号：US20070099979A1
公开(公告)日：2007-05-03
申请号：US11567039
申请日：2006-12-05
申请人： KOJI OHSUMI , Takashi Umemura , Hiroyuki Matsueda , Toshihiro Hatanaka , Akiko Onuki , Katsumi Maezono , Yoko Kageyama , Nobuo Kondo
发明人： KOJI OHSUMI , Takashi Umemura , Hiroyuki Matsueda , Toshihiro Hatanaka , Akiko Onuki , Katsumi Maezono , Yoko Kageyama , Nobuo Kondo
IPC分类号： A61K31/4152 , C07D231/18
CPC分类号： A61K31/7056 , C07H17/02 , Y10S514/866
摘要： The present invention provides pyrazole-O-glycoside derivatives represented by the following formulae, used as a diabetic medicine.
摘要翻译：本发明提供用作糖尿病药的由下式表示的吡唑-O-糖苷衍生物。

5. 发明授权

US07153850B2 Lactam compounds and pharmaceutical use thereof 有权
公开(公告)号：US07153850B2
公开(公告)日：2006-12-26
申请号：US10449774
申请日：2003-06-02
申请人： Yukio Iino , Takao Ikenoue , Nobuo Kondo , Hiroyuki Matsueda , Toshihiro Hatanaka , Ryusuke Hirama , Yoko Masuzawa , Fumio Ohta , Akiyo Yamazaki , Seiji Niwa , Takashi Yamamoto
发明人： Yukio Iino , Takao Ikenoue , Nobuo Kondo , Hiroyuki Matsueda , Toshihiro Hatanaka , Ryusuke Hirama , Yoko Masuzawa , Fumio Ohta , Akiyo Yamazaki , Seiji Niwa , Takashi Yamamoto
IPC分类号： C07D487/04 , C07D498/04 , C07D513/04 , A61K31/5517 , A61P3/10
CPC分类号： C07D487/04 , A61K31/5517 , A61K31/554 , C07D243/10 , C07D513/04
摘要： An agent for increasing the sugar-transporting capacity and an agent for preventing and/or treating diabetes, diabetic peripheral neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic macroangiopathy, impaired glucose tolerance or adiposis, which contains a lactam compound or a pharmaceutically acceptable salt thereof as the active ingredient.

6. 发明申请

US20060189597A1 Lactam compounds and pharmaceutical use thereof 有权
公开(公告)号：US20060189597A1
公开(公告)日：2006-08-24
申请号：US11398675
申请日：2006-04-06
申请人： Yukio Ilno , Takao Ikenoue , Nobuo Kondo , Hiroyuki Matsueda , Toshihiro Hatanaka , Ryusuke Hirama , Yoko Masuzawa , Fumio Ohta , Akiyo Yamazaki , Seiji Niwa , Takashi Yamamoto
发明人： Yukio Ilno , Takao Ikenoue , Nobuo Kondo , Hiroyuki Matsueda , Toshihiro Hatanaka , Ryusuke Hirama , Yoko Masuzawa , Fumio Ohta , Akiyo Yamazaki , Seiji Niwa , Takashi Yamamoto
IPC分类号： A61K31/551 , C07D487/02
CPC分类号： C07D487/04 , A61K31/5517 , A61K31/554 , C07D243/10 , C07D513/04
摘要： An agent for increasing the sugar-transporting capacity and an agent for preventing and/or treating diabetes, diabetic peripheral neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic macroangiopathy, impaired glucose tolerance or adiposis, which contains a lactam compound or a pharmaceutically acceptable salt thereof as the active ingredient.

7. 发明申请

US20050272641A1 Therapeutic agents for diabetes 失效
标题翻译：糖尿病治疗剂
公开(公告)号：US20050272641A1
公开(公告)日：2005-12-08
申请号：US11198511
申请日：2005-08-08
申请人： Takao Ikenoue , Yoko Kageyama , Yukio Iino , Nobuo Kondo
发明人： Takao Ikenoue , Yoko Kageyama , Yukio Iino , Nobuo Kondo
IPC分类号： A61K31/551 , A61K31/5517 , A61K31/553 , A61K31/554 , A61K38/26 , A61K38/28 , A61K45/06 , A61P3/04 , A61P3/10 , A61P43/00 , A61K31/155 , A61K31/426 , A61K31/70 , A61K31/704
CPC分类号： A61K45/06 , A61K31/551 , A61K31/5517 , A61K31/553 , A61K31/554 , A61K38/26 , A61K38/28 , Y10S514/866 , A61K2300/00
摘要： A pharmaceutical composition for preventing and/or treating diabetes, diabetic complication, hyperinsulinemia, disorders of glucose metabolism or obesity, comprising a combination of the following compound, analogues or pharmaceutically acceptable salts thereof with a hypoglycemic agent.
摘要翻译：用于预防和/或治疗糖尿病，糖尿病并发症，高胰岛素血症，葡萄糖代谢紊乱或肥胖症的药物组合物，其包含以下化合物，其类似物或其药学上可接受的盐与降血糖剂的组合。

8. 发明授权

US5098907A Powdery pharmaceutical composition containing benzoyl urea, a dispersant and silicic acid 失效
标题翻译：含有苯甲酸尿素，分散剂和硅酸的粉末药物组合物
公开(公告)号：US5098907A
公开(公告)日：1992-03-24
申请号：US469054
申请日：1990-01-23
申请人： Nobuo Kondo , Masahiro Kikuchi , Tsunetaka Nakajima , Masahiro Watanabe , Kouichi Yamauchi , Takahiro Haga , Nobutoshi Yamada , Hideo Sugi , Toru Koyanagi
发明人： Nobuo Kondo , Masahiro Kikuchi , Tsunetaka Nakajima , Masahiro Watanabe , Kouichi Yamauchi , Takahiro Haga , Nobutoshi Yamada , Hideo Sugi , Toru Koyanagi
IPC分类号： A61K9/14 , A61K31/44 , A61K31/505 , A61K47/14 , A61K47/26 , A61P35/00
CPC分类号： A61K9/14 , A61K31/44 , A61K31/505 , A61K47/14 , A61K47/26 , Y10S514/975
摘要： A powdery pharmaceutical composition comprising a benzoyl urea compound of the formula: ##STR1## wherein X is a halogen atom or a nitro group, Y is a hydrogen atom, a halogen atom, a nitro group or a trifluoromethyl group, Z.sub.1 is a halogen atom or a trifluoromethyl group, Z.sub.2 is a hydrogen atom or a halogen atom, and A is CH or a nitrogen atom, as an active ingredient, a nonionic surfactant as a dispersant, at least one member selected from the group consisting of sugar, sugar-alcohol and a nonionic surfactant as a disintegrant, and anhydrous silicic acid as a fluidizer.

9. 发明授权

US08567013B2 Door body holding structure 有权
标题翻译：门体保持结构
公开(公告)号：US08567013B2
公开(公告)日：2013-10-29
申请号：US13124610
申请日：2009-11-06
申请人： Kiyoshi Yamaoka , Takashi Hibino , Nobuo Kondo , Hideo Ishigure
发明人： Kiyoshi Yamaoka , Takashi Hibino , Nobuo Kondo , Hideo Ishigure
IPC分类号： E05C17/64
CPC分类号： E05D11/1014 , E05D1/04 , E05D11/084 , E05D11/105 , E05Y2201/21 , E05Y2201/424 , E05Y2900/608 , F25C5/182 , F25D23/028 , F25D2323/024 , F25D2400/10 , Y10T16/54 , Y10T16/54038 , Y10T16/543 , Y10T16/551 , Y10T16/61
摘要： A door body holding structure that can hold a door body at an open position by using a simple configuration. A projecting portion 40, which projects toward a containing wall 38 side, is provided on an outer surface of a bearing portion 32 of a fixed-side hinge at a position facing the containing wall 38 where the projecting portion 40 does not come into contact with an inner surface of a guide portion 34 when the door body 18 is at a closed position but the projecting portion 40 comes into contact with the inner surface of the guide portion 34 when the door body 18 is at the open position. A separation dimension between a projecting end of the projecting portion 40 and the containing wall 38 is set to be smaller than a thickness dimension of the guide portion 34. That is, when the inner surface of the guide portion 34 reaches the position at which it comes into contact with the projecting portion 40 by pivoting movement of the door body 18 from the closed position toward the open position, the guide portion 34 is sandwiched and held between the projecting portion 40 and the containing wall 38, thereby holding the door body 18 at the open position.
摘要翻译：一种门体保持结构，其能够通过简单的构造将门体保持在打开位置。朝向容纳壁38侧突出的突出部40设置在固定侧铰链的支承部32的外表面上，在面向容纳壁38的位置处，突出部40不与其接触当门体18处于打开位置时，当门体18处于关闭位置时，突出部分40与引导部分34的内表面接触时，引导部分34的内表面。突出部分40的突出端和容纳壁38之间的间隔尺寸被设定为小于引导部分34的厚度尺寸。也就是说，当引导部分34的内表面到达其位置时通过使门体18从关闭位置朝向打开位置的枢转运动而与突出部40接触，引导部34被夹持并保持在突出部40和容纳壁38之间，从而保持门体18 在开放位置。

10. 发明授权

US07326701B2 Lactam compounds and pharmaceutical use thereof 有权
标题翻译：内酰胺化合物及其药物用途
公开(公告)号：US07326701B2
公开(公告)日：2008-02-05
申请号：US11398675
申请日：2006-04-06
申请人： Yukio Iino , Takao Ikenoue , Nobuo Kondo , Hiroyuki Matsueda , Toshihiro Hatanaka , Ryusuke Hirama , Yoko Masuzawa , Fumio Ohta , Akiyo Yamazaki , Seiji Niwa , Takashi Yamamoto
发明人： Yukio Iino , Takao Ikenoue , Nobuo Kondo , Hiroyuki Matsueda , Toshihiro Hatanaka , Ryusuke Hirama , Yoko Masuzawa , Fumio Ohta , Akiyo Yamazaki , Seiji Niwa , Takashi Yamamoto
IPC分类号： C07D487/04 , A61K31/5517 , A61P3/10
CPC分类号： C07D487/04 , A61K31/5517 , A61K31/554 , C07D243/10 , C07D513/04
摘要： An agent for increasing the sugar-transporting capacity and an agent for preventing and/or treating diabetes, diabetic peripheral neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic macroangiopathy, impaired glucose tolerance or adiposis, which contains a lactam compound or a pharmaceutically acceptable salt thereof as the active ingredient.
摘要翻译：含有内酰胺化合物或其药学上可接受的盐的增加糖输送能力的药剂和用于预防和/或治疗糖尿病，糖尿病性周围神经病变，糖尿病性肾病，糖尿病性视网膜病变，糖尿病性大血管病变，葡萄糖耐量异常或脂肪变性的药剂作为活性成分。

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