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1. 发明申请

US20130158303A1 METHOD FOR SEPARATING BUTANOL 有权
标题翻译：分离丁醇的方法
公开(公告)号：US20130158303A1
公开(公告)日：2013-06-20
申请号：US13814490
申请日：2011-04-15
申请人： Hanjie Ying , Xiaoqing Lin , Yong Chen , Xiaochun Chen , Jianxin Bai , Jian Xiong , Wenbin Qian , Jingjing Xie , Jinglan Wu
发明人： Hanjie Ying , Xiaoqing Lin , Yong Chen , Xiaochun Chen , Jianxin Bai , Jian Xiong , Wenbin Qian , Jingjing Xie , Jinglan Wu
IPC分类号： C07C29/76
CPC分类号： C07C29/76 , C07C31/12
摘要： Disclosed is a method for separating butanol. The method uses hydrophobic macroporous polymer adsorbent to separate butanol in a mixed solution, and the process comprises the following steps: 1) using macroporous polymer adsorbent to adsorb butanol in a mixed solution; 2) desorbing butanol from macroporous polymer adsorbent. The method is simple; the separation time is short; the efficiency of butanol recovery is high; and the separating cost is low.
摘要翻译：公开了一种分离丁醇的方法。该方法使用疏水性大孔聚合物吸附剂在混合溶液中分离丁醇，该方法包括以下步骤：1）使用大孔聚合物吸附剂在混合溶液中吸附丁醇; 2）从大孔聚合物吸附剂中解吸丁醇。方法简单; 分离时间短; 丁醇回收效率高; 分离成本低。

2. 发明申请

US20130052691A1 METHOD FOR MICROBIAL PRODUCTION OF CYCLIC ADENOSINE 3', 5'-MONOPHOSPHATE 有权
标题翻译：用于微生物生产循环腺苷3'，5'-单磷酸酯的方法
公开(公告)号：US20130052691A1
公开(公告)日：2013-02-28
申请号：US13634513
申请日：2011-03-10
申请人： Hanjie Ying , Jianxin Bai , He Song , Xiaochun Chen , Jian Xiong , Yong Chen , Jingjing Xie , Jinglan Wu
发明人： Hanjie Ying , Jianxin Bai , He Song , Xiaochun Chen , Jian Xiong , Yong Chen , Jingjing Xie , Jinglan Wu
IPC分类号： C12P19/32
CPC分类号： C12P19/32 , C12N1/20 , C12N11/16
摘要： Disclosed is a method for the production of cyclic adenosine 3′,5′-monophosphate (cAMP) by permeable microbial strain, which uses polyols for protecting activities of enzymes, uses cAMP precursor and phosphate radical ions as substrates, uses glucose as energy provider, and uses metal ions in the mendium. The method is simple, economical and has high yield.
摘要翻译：公开了一种通过可渗透微生物菌株生产环腺苷3'，5'-单磷酸（cAMP）的方法，其使用多元醇保护酶的活性，使用cAMP前体和磷酸根离子作为底物，使用葡萄糖作为能量提供者，并在金属中使用金属离子。该方法简单，经济，成品率高。

3. 发明申请

US20110124649A1 INHIBITORS OF HUMAN METHIONINE AMINOPEPTIDASE 1 AND METHODS OF TREATING DISORDERS 审中-公开
标题翻译：人甲氨喋呤氨基转移酶1的抑制剂和治疗疾病的方法
公开(公告)号：US20110124649A1
公开(公告)日：2011-05-26
申请号：US12742208
申请日：2008-11-10
申请人： Jun O. Liu , Xiaoyi Hu , Xiaochun Chen , Dawei Ma , Shridhar Bhat
发明人： Jun O. Liu , Xiaoyi Hu , Xiaochun Chen , Dawei Ma , Shridhar Bhat
IPC分类号： A61K31/53 , C07D401/04 , A61K31/506 , A61P35/00 , A61K31/517 , A61K31/519
CPC分类号： C07D401/04 , C07D401/14 , C07D405/14 , C07D471/10
摘要： Described herein are novel pyrimidine-pyridine compounds, methods of inhibiting methionine aminopeptidase and treating disorders (or symptoms thereof) associated with methionine aminopeptidase, wherein a compound of the invention is administered to a subject.
摘要翻译：本文描述的是新颖的嘧啶 - 吡啶化合物，抑制甲硫氨酸氨基肽酶的方法和治疗与甲硫氨酸氨基肽酶相关的病症（或其症状），其中将本发明的化合物施用于受试者。

4. 发明申请

US20050014364A1 Method of suppressing the effect of shining spots present at the edge of a wafer 审中-公开
标题翻译：抑制存在于晶片边缘的闪光斑的影响的方法
公开(公告)号：US20050014364A1
公开(公告)日：2005-01-20
申请号：US10622607
申请日：2003-07-18
申请人： Xiaochun Chen , Kangguo Cheng , Mai Randall
发明人： Xiaochun Chen , Kangguo Cheng , Mai Randall
IPC分类号： B32B5/12 , H01L21/302 , H01L21/308 , H01L21/44 , H01L21/8242
CPC分类号： H01L21/3083 , H01L27/10864 , H01L27/1087
摘要： Devices formed in a substrate are protected from shining spots present in a periphery of the substrate. A ring of material is formed on the substrate to separate the periphery of the substrate from a further region of the substrate where the devices are formed.
摘要翻译：在衬底中形成的器件被保护以避免存在于衬底周边的闪光点。在基板上形成材料环，以将衬底的周边与形成器件的衬底的另一区域分离。

5. 发明授权

US09249433B2 Clostridium acetobutylicum and application thereof 有权
标题翻译：丙酮丁醇梭菌及其应用
公开(公告)号：US09249433B2
公开(公告)日：2016-02-02
申请号：US14386286
申请日：2012-03-20
申请人： Hanjie Ying , Dong Liu , Yong Chen , An Li , Tao Zhou , Jinglan Wu , Xiaoqing Lin , Xiaochun Chen , Jingjing Xie , Jianxin Bai
发明人： Hanjie Ying , Dong Liu , Yong Chen , An Li , Tao Zhou , Jinglan Wu , Xiaoqing Lin , Xiaochun Chen , Jingjing Xie , Jianxin Bai
IPC分类号： C12P7/26 , C12R1/145 , C12N1/20 , C12P7/16
CPC分类号： C12P7/26 , C12N1/20 , C12P7/16 , C12R1/145 , Y02E50/10
摘要： The present invention provides Clostridium acetobutylicum and an application thereof. A preservation number of the Clostridium acetobutylicum provided in the invention is CGMCC No. 5234. The Clostridium acetobutylicum provided in the present invention can be used for cogeneration of acetone, butanol, ethanol, and 3-hydroxy butanone through fermentation, so as to improve the economic benefit of butanol fermentation. NAD+ coupling and regeneration can be implemented by adding metabolism or growth regulating substances, so as to improve the product yield, and at the same time, the yield of cogeneration products can be flexibly adjusted, so as to cater for the market demand.
摘要翻译：本发明提供丙酮丁醇梭菌及其应用。本发明提供的丙酮丁醇梭菌的保藏号为CGMCC号5234.本发明提供的丙酮丁醇梭菌可通过发酵用于丙酮，丁醇，乙醇和3-羟基丁酮的热电联供，以改善丁醇发酵的经济效益。 NAD +偶联和再生可以通过添加新陈代谢或生长调节物质来实现，从而提高产品产量，同时可以灵活调整热电产品的产量，以满足市场需求。

6. 发明申请

US20060021423A1 Tank container with electronic monitoring device 有权
标题翻译：带集装箱的电子监控装置
公开(公告)号：US20060021423A1
公开(公告)日：2006-02-02
申请号：US11192261
申请日：2005-07-28
申请人： Shouqin Zhou , Xiaochun Chen , Rong Liu , Wenqing Yuan , Chenguang Zhou , Jianbin Zhu
发明人： Shouqin Zhou , Xiaochun Chen , Rong Liu , Wenqing Yuan , Chenguang Zhou , Jianbin Zhu
IPC分类号： G01M3/04
CPC分类号： G01M3/186
摘要： A tank container with electronic monitoring device includes a tank barrel and a container frame supporting the same. The tank barrel includes a valve assembly and a valve assembly protection box. The electronic monitoring device is installed inside the valve assembly protection box, or on a sealing surface of the tank barrel, or in a range of the container frame outside the tank barrel. The electronic monitoring device includes a sensor for detecting a leakage condition of the cargoes contained in the tank container and transmitting an information data related to the leakage condition, and a data processing module connected with the sensor for processing the data. The invention can be used for detecting a sealing condition of a sealing surface and an illegal open of a lid of the valve assembly protection box as well as for realizing a global tracking, whereby ensuring a safe transport for containers.
摘要翻译：具有电子监控装置的储罐容器包括罐筒和支撑该容器的容器框架。罐筒包括阀组件和阀组件保护盒。电子监控装置安装在阀组件保护箱内，或者在罐筒的密封表面上，或者在罐筒外部的容器框架的范围内。该电子监视装置包括：传感器，用于检测容纳在罐箱中的货物的泄漏状况，并发送与泄漏状况相关的信息数据;以及数据处理模块，与传感器连接以处理数据。本发明可用于检测密封面的密封状态和阀组件保护盒的盖子的非法打开以及实现全局跟踪，从而确保容器的安全运输。

7. 发明授权

US11027016B2 Pharmaceutical preparation stably comprising CD147 monoclonal antibody 有权
公开(公告)号：US11027016B2
公开(公告)日：2021-06-08
申请号：US16461799
申请日：2017-12-27
申请人： Xiaochun Chen
发明人： Hao Tang , Qiang Feng , Tianyi Yang , Mingxi Chen
IPC分类号： A61K39/395 , A61K9/08 , A61K47/02 , A61K47/12 , A61K47/22 , A61K47/26 , A61K9/00
摘要： Disclosed is a pharmaceutical preparation comprising a CD147 monoclonal antibody, a buffer, a protein protectant and a surfactant. The pharmaceutical preparation can maintain the stability of the CD147 monoclonal antibody over a long period of time. Also disclosed are the use of the pharmaceutical preparation in the preparation of a drug for treating CD147-related diseases, in particular non-small cell lung cancer, and a method for preparing the pharmaceutical preparation.

8. 发明授权

US09108897B2 Method for desorbing and regenerating butanol-adsorbing hydrophobic macroporous polymer adsorbent 有权
标题翻译：解吸和再生丁醇吸附疏水性大孔聚合物吸附剂的方法
公开(公告)号：US09108897B2
公开(公告)日：2015-08-18
申请号：US14130887
申请日：2011-07-05
申请人： Hanjie Ying , Xiaoqing Lin , Jiansheng Fan , Jinglan Wu , Yong Chen , Xiaochun Chen , Jingjing Xie , Jian Xiong , Jianxin Bai
发明人： Hanjie Ying , Xiaoqing Lin , Jiansheng Fan , Jinglan Wu , Yong Chen , Xiaochun Chen , Jingjing Xie , Jian Xiong , Jianxin Bai
IPC分类号： B01J38/48 , C07C29/76 , B01D15/20 , B01J20/34 , B01D15/42
CPC分类号： C07C29/76 , B01D15/203 , B01D15/426 , B01J20/3425 , B01J20/3475 , C08J7/02 , C08J11/02 , C08J2325/04 , C07C31/12
摘要： The present invention provides a method for desorbing and regenerating a butanol-adsorbing hydrophobic macroporous polymer adsorbent, comprising: successively eluting the hydrophobic macroporous polymer adsorbent with butanol adsorbed therein using a water soluble low-boiling-point polar solvent and water. The method provided in the present invention has a simple process, a short separation time, easy, fast and complete desorption and regeneration, low equipment investment and pollution, and reduced energy consumption, and therefore production is easy on a large scale.
摘要翻译：本发明提供了一种用于解吸和再生丁醇吸附的疏水性大孔聚合物吸附剂的方法，其包括：使用水溶性低沸点极性溶剂和水连续洗脱其中吸附有丁醇的疏水性大孔聚合物吸附剂。本发明提供的方法工艺简单，分离时间短，解吸和再生容易，快速，完整，设备投资少，污染少，能耗低等特点，生产容易。

9. 发明申请

US20130090466A1 CRYSTALLIZATION PROCESS OF CYCLIC ADENOSINE 3',5'-MONOPHOSPHATE 审中-公开
标题翻译：循环腺苷3'，5'-单磷酸酯的结晶过程
公开(公告)号：US20130090466A1
公开(公告)日：2013-04-11
申请号：US13702039
申请日：2011-04-21
申请人： Hanjie Ying , Wenbin Qian , Yong Chen , Xiaochun Chen , Jianxin Bai , Jian Xiong , Xiaoqing Lin , Jingjing Xie , Jinglan Wu
发明人： Hanjie Ying , Wenbin Qian , Yong Chen , Xiaochun Chen , Jianxin Bai , Jian Xiong , Xiaoqing Lin , Jingjing Xie , Jinglan Wu
IPC分类号： C07H19/16
CPC分类号： C07H19/16 , C07H1/06 , C07H19/213
摘要： Provided is a crystallization process of cyclic adenosine 3′,5′-monophosphate, which comprises the following steps: 1) reacting an aqueous solution of cyclic adenosine 3′,5′-monophosphate with a base to obtain a salt of cyclic adenosine 3′,5′-monophosphate; 2) reacting the cyclic adenosine 3′,5′-monophosphate salt solution obtained in step 1) with an acid to obtain cyclic adenosine 3′,5′-monophosphate; 3) keeping cyclic adenosine 3′,5′-monophosphate obtained in step 2) at 0-15° C.
摘要翻译：提供环腺苷3'，5'-单磷酸的结晶过程，其包括以下步骤：1）使环腺苷3'，5'-单磷酸的水溶液与碱反应，得到环腺苷3' ，5'-单磷酸 2）使步骤1）中得到的环状腺苷3'，5'-单磷酸盐溶液与酸反应，得到环状腺苷3'，5'-单磷酸; 3）在0-15℃保持步骤2）中获得的环腺苷3'，5'-单磷酸

10. 发明申请

US20060222137A1 STORAGE EFFICIENT SLIDING WINDOW SUM 失效
标题翻译：存储高效滑动窗口SUM
公开(公告)号：US20060222137A1
公开(公告)日：2006-10-05
申请号：US11306986
申请日：2006-01-18
申请人： Cindy Wang , Xiangyang Xu , Xiaochun Chen
发明人： Cindy Wang , Xiangyang Xu , Xiaochun Chen
IPC分类号： H04L7/00
CPC分类号： H04L27/22 , H03K2005/00241 , H04L27/2275 , H04L2025/03401 , H04L2027/0046 , H04L2027/0063
摘要： A delay buffer includes a first shift register receiving input data and having a shift signal input port. The first shift register right shifts the input data responsive to a shift signal on the shift signal input port. The shift signal is determined based on an effective bit width of the input data. A first delay line receives the shifted data from the first shift register while a second delay line of equal length to the first delay line receives the shift signal. A second shift register receives the output from the first delay line and receives the output of the second delay line on a shift signal input port. The second shift register then left shifts the data contained therein according to the shift signal.
摘要翻译：延迟缓冲器包括接收输入数据并具有移位信号输入端口的第一移位寄存器。第一移位寄存器根据移位信号输入端口上的移位信号，右移位输入数据。基于输入数据的有效位宽来确定移位信号。第一延迟线接收来自第一移位寄存器的移位数据，而与第一延迟线等长的第二延迟线接收移位信号。第二移位寄存器接收来自第一延迟线的输出，并接收移位信号输入端口上的第二延迟线的输出。然后，第二移位寄存器根据移位信号移位其中包含的数据。

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