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1. 发明申请

WO2021004620A1 COMPUTATION OF A BREATHING CURVE FOR MEDICAL APPLICATIONS 审中-公开
公开(公告)号：WO2021004620A1
公开(公告)日：2021-01-14
申请号：PCT/EP2019/068282
申请日：2019-07-08
申请人： BRAINLAB AG
发明人： BERLINGER, Kajetan , KAISER, Hagen
IPC分类号： A61N5/10
摘要： A computer-implemented medical method of determining a breathing signal (202) of a patient (100) is disclosed. The method comprises determining a motion trajectory (120) of a structure (104) associated with at least one body part of the patient (100), the motion trajectory (120) being indicative of a respiratory movement of the structure (104); acquiring surface data (50) representative of a position of a surface region (106) of the patient (100); computing an intersection of the determined motion trajectory (120) and the acquired surface data (50); and determining a breathing signal (202) of the patient (100) based on the computed intersection, wherein the breathing signal (202) is indicative of a breathing state of the patient (100).

2. 发明申请

WO2020094226A1 COMPARTMENTALIZED DYNAMIC ATLAS 审中-公开
公开(公告)号：WO2020094226A1
公开(公告)日：2020-05-14
申请号：PCT/EP2018/080491
申请日：2018-11-07
申请人： BRAINLAB AG
发明人： BERLINGER, Kajetan , BLUMHOFER, Andreas
IPC分类号： G16H30/40 , G16H50/70
摘要： A compartmentalized dynamic anatomic atlas is disclosed, comprising static atlas data comprising spatial element data and element representation data, wherein the spatial element data describes spatial properties of a spatial atlas element and wherein the element representation data describes representational properties assignable to the spatial atlas element, the atlas further comprising dynamic atlas data comprising information on a dynamic property which information is respectively linked to the spatial atlas element.

3. 发明申请

WO2018153675A1 MULTI IMAGE FUSION BASED POSITIONING VERIFICATION 审中-公开
公开(公告)号：WO2018153675A1
公开(公告)日：2018-08-30
申请号：PCT/EP2018/053100
申请日：2018-02-07
申请人： BRAINLAB AG
发明人： BERLINGER, Kajetan , STEAD, Michael
IPC分类号： G06T7/30
摘要： The present invention involves positionally identifying several anatomical structures of interest of a patient's anatomy on images which have been acquired at different points of time. For each anatomical structure a separate image fusion transformation between these images is performed. For at least one of the image fusion transformations it is then determined whether this transformation is within a predetermined threshold, wherein for this determination, at least one further image fusion transformation of another anatomical structure is taken into account.

4. 发明申请

WO2015120906A1 FRAMELESS PRE-POSITIONING FOR RADIOSURGERY 审中-公开
标题翻译：无缝预处理放射治疗
公开(公告)号：WO2015120906A1
公开(公告)日：2015-08-20
申请号：PCT/EP2014/052932
申请日：2014-02-14
申请人： BRAINLAB AG
发明人： GRUBER, Eva Maria , BERLINGER, Kajetan , FROEHLICH, Stephan
IPC分类号： A61B6/00 , A61N5/10
CPC分类号： A61B6/0492 , A61B6/032 , A61B6/0421 , A61B6/501 , A61B6/5211 , A61B6/547 , A61B90/14 , A61B90/39 , A61B2034/2055 , A61B2090/101 , A61B2090/364 , A61B2090/3937 , A61B2090/3983 , A61N5/1049 , A61N5/1069 , A61N2005/1061 , G01T7/005 , G06F19/00 , G06K9/00208 , G06K9/2054 , G06K9/2063 , G06K9/32 , G06K9/3216 , G06K9/6212 , G06K2009/2045 , G06K2009/3225 , G06K2009/3291 , G06T7/0014 , G06T7/74 , G06T2207/10081 , G06T2207/20221 , G06T2207/30004 , G06T2207/30204 , G06T2207/30208 , G06T2219/2004
摘要： A medical data processing method of determining positioning control data describing a positioning procedure for positioning an anatomical body part (2) of a patient (1), the method being constituted to be executed by a computer (11) and comprising the following steps: a) acquiring (SI) reference medical image data describing a reference image representation of a reference structure (3); b) acquiring (S2) patient medical image data describing a patient image representation of the anatomical body part (2) and the reference structure (3); c) acquiring treatment position data describing a predetermined treatment position of the anatomical body part (2) which it shall attain for conducting an envisaged medical procedure; d) acquiring marker reference position data describing a predetermined spatial relationship between a marker device (4) and the reference structure (3); e) acquiring actual marker position data describing the actual position of the marker device (4); f) determining, based on the reference medical image data and the patient medical image data, body part reference position data describing the spatial relationship between the anatomical body part (2) and the reference structure (3); g) determining, based on the body part reference position data and the marker reference position data, body part marker position data describing the spatial relationship between the anatomical body part (2) and the marker device (4); h) determining (S4), based on the treatment position data and the marker reference position data and the body part marker position data, positioning control data describing a positioning procedure for positioning the anatomical body part (2).
摘要翻译：一种医疗数据处理方法，用于确定描述用于定位患者（1）的解剖体部分（2）的定位过程的定位控制数据，所述方法被构造为由计算机（11）执行，并且包括以下步骤：获取描述参考结构（3）的参考图像表示的参考医学图像数据（SI）; b）获取（S2）描述解剖体部分（2）和参考结构（3）的患者图像表示的患者医学图像数据; c）获取描述解剖体部分（2）的预定治疗位置的治疗位置数据，所述治疗位置数据应用于进行设想的医疗程序; d）获取描述标记装置（4）和参考结构（3）之间的预定空间关系的标记参考位置数据; e）获取描述所述标记装置（4）的实际位置的实际标记位置数据; f）基于参考医学图像数据和患者医学图像数据确定描述解剖体部分（2）和参考结构（3）之间的空间关系的身体部位参考位置数据; g）基于身体部位参考位置数据和标记参考位置数据确定描述解剖体部分（2）和标记装置（4）之间的空间关系的身体部位标记位置数据; h）基于所述治疗位置数据和所述标记参考位置数据和所述身体部位标记位置数据确定（S4），描述用于定位所述解剖体部分（2）的定位过程的定位控制数据。

5. 发明申请

WO2014108174A1 CBCT AND X-RAY COMBINED SETUP WITH X-RAY VERIFICATION OF PATIENT POSITIONING 审中-公开
标题翻译： CBCT和X射线组合设置与X射线验证患者定位
公开(公告)号：WO2014108174A1
公开(公告)日：2014-07-17
申请号：PCT/EP2013/050240
申请日：2013-01-09
申请人： BRAINLAB AG
发明人： BERLINGER, Kajetan , KNORR, Sebastian , SCHLOSSBAUER, Cornel , REHS, Joerg
IPC分类号： G06T7/00
CPC分类号： A61N5/1049 , A61B6/032 , A61B6/04 , A61B6/4085 , A61N5/1037 , A61N5/107 , A61N5/1071 , A61N5/1077 , A61N2005/1061 , A61N2005/1062 , A61N2005/1072 , A61N2005/1074 , G06T7/0012 , G06T7/30 , G06T2207/10072
摘要： The invention is directed to a data processing method for determining the consistency of registration of the position of a treatment body part to be treated by radiotherapy with a treatment beam arrangement of at least one position of a treatment beam issued by a treatment device, the treatment body part being a soft tissue part of an anatomical structure of a patient's body and the data processing method being constituted to be executed by a computer and comprising the following steps: g) acquiring CT data comprising predetermined CT information about a position of the treatment body part relative to a bony structure of the patient's body and about a first position of the bony structure relative to the treatment beam arrangement; h) acquiring x-ray data comprising x-ray information about a second position of the bony structure relative to the treatment beam arrangement; i) determining, based on the x-ray data and the CT data, bony structure position first transformation data comprising bony structure position first transformation information about a first transformation between the first position and the second position of the bony structure; j) acquiring CBCT data comprising CBCT information about the position of the treatment body part relative to the treatment beam arrangement or relative to the bony structure; k) determining, based on the CBCT data and the CT data, bony structure position second transformation data comprising bony structure position second transformation information about a second transformation between the first position and a third position of the bony structure relative to the treatment beam arrangement; determining, based on the bony structure position first transformation data and the bony structure position second transformation data, transformation difference data comprising transformation difference information about a difference between the first and second transformations.
摘要翻译：本发明涉及一种数据处理方法，用于确定通过放射疗法治疗的治疗体部位的位置的一致性与由治疗装置发出的治疗束的至少一个位置的治疗束布置，治疗身体部分是患者身体的解剖结构的软组织部分，并且所述数据处理方法被构造为由计算机执行，并且包括以下步骤：g）获取包括关于治疗体的位置的预定CT信息的CT数据相对于患者身体的骨骼结构以及关于骨结构相对于治疗束布置的第一位置的部分; h）获取X射线数据，其包括关于所述骨结构相对于所述治疗束装置的第二位置的x射线信息; i）基于X射线数据和CT数据确定骨结构位置第一变换数据，其包括关于骨结构的第一位置和第二位置之间的第一变换的骨结构位置第一变换信息; j）获取CBCT数据，其包括关于治疗体部分相对于治疗束布置或相对于骨结构的位置的CBCT信息; k）基于所述CBCT数据和所述CT数据确定骨结构位置第二变换数据，所述骨结构位置第二变换数据包括关于所述骨结构的所述第一位置和所述第三位置之间相对于所述治疗束布置的第二变换的骨结构位置第二变换信息; 基于骨结构位置第一变换数据和骨结构位置第二变换数据，确定包括关于第一和第二变换之间的差的变换差分信息的变换差分数据。

6. 发明申请

WO2018228673A1 BINARY TRACKING ON MEDICAL IMAGES 审中-公开
公开(公告)号：WO2018228673A1
公开(公告)日：2018-12-20
申请号：PCT/EP2017/064396
申请日：2017-06-13
申请人： BRAINLAB AG
发明人： DOMNIK, Birte , BERLINGER, Kajetan
IPC分类号： G16H20/40 , A61B6/00
CPC分类号： G16H20/40 , A61B6/00 , A61B6/5205
摘要： Disclosed is a computer-implemented method for determining the position of an anatomical tracking structure in a tracking image usable for controlling radiation treatment such as at least one of radiotherapy or radio surgery of a patient, a corresponding computer program, a non-transitory program storage medium storing such a program and a computer for executing the program, as well as a system for the position of an anatomical tracking structure in a tracking image usable for controlling radiation treatment such as at least one of radiotherapy or radio surgery of a patient, the system comprising an electronic data storage device and the aforementioned computer.

7. 发明申请

WO2016087059A1 MEDICAL CAMERA ASSEMBLY COMPRISING RANGE CAMERA AND THERMOGRAPHIC CAMERA 审中-公开
标题翻译：医疗相机组件包括范围相机和热像仪
公开(公告)号：WO2016087059A1
公开(公告)日：2016-06-09
申请号：PCT/EP2015/059542
申请日：2015-04-30
申请人： BRAINLAB AG
发明人： KAISER, Hagen , BERLINGER, Kajetan
IPC分类号： A61B5/01 , A61B5/11 , G01J5/00
CPC分类号： A61B5/1128 , A61B5/0035 , A61B5/0064 , A61B5/0077 , A61B5/015 , A61B5/055 , A61B5/11 , A61B5/113 , A61B5/7292 , A61B6/032 , A61B6/5247 , A61B2560/0223 , A61B2576/00 , A61B2576/02 , A61N5/1049 , A61N5/1068 , A61N5/1069 , G01J5/00 , G01J5/10 , G01J2005/0077 , G01J2005/0081 , G01R33/4808 , G03B35/02 , G06F19/00 , G06T7/0012 , G06T7/33 , G06T7/70 , G06T2207/10004 , G06T2207/10028 , G06T2207/10048 , G06T2207/10081 , G06T2207/10088 , G06T2207/30196 , H04N13/204 , H04N13/239 , H04N2013/0081
摘要： A camera assembly (3) for use in medical tracking applications, comprising a range camera (4) and a thermographic camera (5) in a fixed relative position.
摘要翻译：一种用于医疗跟踪应用的相机组件（3），包括位于固定相对位置的量程相机（4）和热成像相机（5）。

8. 发明申请

WO2016087058A1 DETERMINATION OF BREATHING SIGNAL FROM THERMAL IMAGES 审中-公开
标题翻译：从热像测定呼吸信号
公开(公告)号：WO2016087058A1
公开(公告)日：2016-06-09
申请号：PCT/EP2015/059171
申请日：2015-04-28
申请人： BRAINLAB AG
发明人： KAISER, Hagen , BERLINGER, Kajetan
IPC分类号： A61B5/113 , A61N5/10 , A61B5/01
CPC分类号： A61B5/1128 , A61B5/0035 , A61B5/0064 , A61B5/0077 , A61B5/015 , A61B5/055 , A61B5/11 , A61B5/113 , A61B5/7292 , A61B6/032 , A61B6/5247 , A61B2560/0223 , A61B2576/00 , A61B2576/02 , A61N5/1049 , A61N5/1068 , A61N5/1069 , G01J5/00 , G01J5/10 , G01J2005/0077 , G01J2005/0081 , G01R33/4808 , G03B35/02 , G06F19/00 , G06T7/0012 , G06T7/33 , G06T7/70 , G06T2207/10004 , G06T2207/10028 , G06T2207/10048 , G06T2207/10081 , G06T2207/10088 , G06T2207/30196 , H04N13/204 , H04N13/239 , H04N2013/0081
摘要： A data processing method performed by a computer for determining breathing signal data which represents a breathing cycle of a patient, comprising the steps of: - acquiring image data representing a sequence of training thermal images of at least a part of the surface of the patient's body over time, the sequence covering at least one half breathing cycle and being captured by a thermographic camera; and - tracking at least one tracked point in the image data over the sequence of training thermal images to find a trajectory of the tracked point as the breathing signal data, wherein the tracked point is a point on the surface of the patient's body.
摘要翻译：一种由计算机执行的用于确定代表患者的呼吸周期的呼吸信号数据的数据处理方法，包括以下步骤： - 获取表示患者身体表面的至少一部分的训练热图像序列的图像数据随着时间的推移，该序列覆盖至少一个半呼吸周期并被热成像摄影机捕获; 以及 - 跟踪训练热图像序列上的图像数据中的至少一个跟踪点，以找到跟踪点的轨迹作为呼吸信号数据，其中跟踪点是患者身体表面上的点。

9. 发明申请

WO2011107145A1 TRACKING REPRESENTATIONS OF INDICATOR BODY PARTS 审中-公开
标题翻译：跟踪指示器部件的表示
公开(公告)号：WO2011107145A1
公开(公告)日：2011-09-09
申请号：PCT/EP2010/052619
申请日：2010-03-02
申请人： BRAINLAB AG , BERLINGER, Kajetan , BRUMME, Stephan
发明人： BERLINGER, Kajetan , BRUMME, Stephan
IPC分类号： G06T7/00 , G06T7/20
CPC分类号： A61N5/1049 , A61N2005/1055 , A61N2005/1061 , A61N2005/1087 , G06T7/238 , G06T7/251 , G06T7/70 , G06T2207/10076 , G06T2207/10081 , G06T2207/10088 , G06T2207/20021 , G06T2207/30008 , G06T2207/30096 , G06T2207/30241
摘要： The present invention relates to a method for tracking image sections which represent indicator body parts of a body in a process sequence of images, wherein changes in the position of the indicator body parts are used as an indicator for changes in the position of a treatment body part of the body which is to be treated using a treatment beam, said method comprising the following steps: providing advance image data which describe an advance sequence of images representing a result of an advance analysis of the body; providing process image data which describe the process sequence of images, wherein the process sequence of images represents a result of a process analysis of the body which is performed after the advance analysis; determining, on the basis of the advance image data, sub-images which undergo similar changes in position in the advance sequence; extracting, on the basis of the process image data and the determined sub-images, image sections from the images of the process sequence which have an image content which corresponds to the image content of the determined sub-images; and tracking the extracted image sections in the process sequence.
摘要翻译：本发明涉及一种跟踪图像部分的方法，该图像部分以图像的处理顺序表示身体的指示体部分，其中指示体部分的位置的改变用作治疗体位置变化的指标所述方法包括以下步骤：提供描述表示身体前进分析结果的图像的预先顺序的提前图像数据; 提供描述图像的处理顺序的处理图像数据，其中图像的处理序列表示在进行分析之后执行的身体的处理分析的结果; 基于所述提前图像数据确定在所述提前序列中经历相似位置改变的子图像; 根据处理图像数据和所确定的子图像，从具有与所确定的子图像的图像内容相对应的图像内容的处理序列的图像中提取图像部分; 并且在处理序列中跟踪提取的图像部分。

10. 发明申请

WO2021028022A1 TRIGGERING OF X-RAY-IMAGES BASED ON SURFACE MEASUREMENTS 审中-公开
公开(公告)号：WO2021028022A1
公开(公告)日：2021-02-18
申请号：PCT/EP2019/071660
申请日：2019-08-13
申请人： BRAINLAB AG
发明人： BERLINGER, Kajetan , KAISER, Hagen , STEAD, Michael
IPC分类号： A61B6/08 , A61B6/00 , A61N5/10
摘要： The present invention relates to a computer-implemented medical method for monitoring a spatial position of a patient's body part (8), wherein at least one optimum spatial direction for a line of sight of a check x-ray-image is determined, that qualifies for quantifying a deviation of the spatial position of the patient's body part (8) from a target spatial position for the patient's body part (8). The present invention further relates to a corresponding computer program and a corresponding medical system (1).

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