专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09474762B2 Triazolopyridine compounds 有权
标题翻译：三唑并吡啶化合物
公开(公告)号：US09474762B2
公开(公告)日：2016-10-25
申请号：US14716159
申请日：2015-05-19
申请人： Chao Chen , Haibing Deng , Haibing Guo , Feng He , Lei Jiang , Fang Liang , Yuan Mi , Huixin Wan , Yao-Chang Xu , Hongping Yu , Ji Yue Zhang
发明人： Chao Chen , Haibing Deng , Haibing Guo , Feng He , Lei Jiang , Fang Liang , Yuan Mi , Huixin Wan , Yao-Chang Xu , Hongping Yu , Ji Yue Zhang
IPC分类号： A61K31/00 , A61K31/551 , C07D471/04 , C07D519/00 , A61K31/437 , A61K31/496 , A61K31/5377 , A61K31/5513 , A61K45/06 , C07D491/107 , A61K31/4709
CPC分类号： A61K31/551 , A61K31/437 , A61K31/4709 , A61K31/496 , A61K31/5377 , A61K31/5513 , A61K45/06 , C07D471/04 , C07D491/107 , C07D519/00
摘要： The invention relates to compounds of formula (I) and salts thereof: wherein the substituents are as defined in the specification; a compound of formula (I) for use in the treatment of the human or animal body, in particular with regard to c-Met tyrosine kinase mediated diseases or conditions; the use of a compound of formula (I) for manufacturing a medicament for the treatment of such diseases; pharmaceutical compositions comprising a compound of the formula (I), optionally in the presence of a combination partner, and processes for the preparation of a compound of formula (I).

2. 发明申请

US20150250799A1 Triazolopyridine Compounds 审中-公开
标题翻译：三唑并吡啶化合物
公开(公告)号：US20150250799A1
公开(公告)日：2015-09-10
申请号：US14716159
申请日：2015-05-19
申请人： Chao CHEN , Haibing DENG , Haibing Guo , Feng HE , Lei Jiang , Fang Liang , Yuan Mi , Huixin Wan , Yao-Chang Xu , Hongping Yu , Ji Yue Zhang
发明人： Chao CHEN , Haibing DENG , Haibing Guo , Feng HE , Lei Jiang , Fang Liang , Yuan Mi , Huixin Wan , Yao-Chang Xu , Hongping Yu , Ji Yue Zhang
IPC分类号： A61K31/551 , A61K31/496 , A61K31/5377 , A61K31/4709
CPC分类号： A61K31/551 , A61K31/437 , A61K31/4709 , A61K31/496 , A61K31/5377 , A61K31/5513 , A61K45/06 , C07D471/04 , C07D491/107 , C07D519/00
摘要： The invention relates to compounds of formula (I) and salts thereof: wherein the substituents are as defined in the specification; a compound of formula (I) for use in the treatment of the human or animal body, in particular with regard to c-Met tyrosine kinase mediated diseases or conditions; the use of a compound of formula (I) for manufacturing a medicament for the treatment of such diseases; pharmaceutical compositions comprising a compound of the formula (I), optionally in the presence of a combination partner, and processes for the preparation of a compound of formula (I).
摘要翻译：本发明涉及式（I）的化合物及其盐：其中取代基如说明书中所定义; 用于治疗人或动物体的式（I）化合物，特别是关于c-Met酪氨酸激酶介导的疾病或病症; 使用式（I）化合物制备用于治疗这些疾病的药物; 包含式（I）化合物，任选在组合配偶体存在下的药物组合物，以及制备式（I）化合物的方法。

3. 发明授权

US09062045B2 Triazolopyridine compounds 有权
标题翻译：三唑并吡啶化合物
公开(公告)号：US09062045B2
公开(公告)日：2015-06-23
申请号：US13613291
申请日：2012-09-13
申请人： Chao Chen , Haibing Deng , Haibing Guo , Feng He , Lei Jiang , Fang Liang , Yuan Mi , Huixin Wan , Yao-Chang Xu , Hongping Yu , Ji Yue (Jeff) Zhang
发明人： Chao Chen , Haibing Deng , Haibing Guo , Feng He , Lei Jiang , Fang Liang , Yuan Mi , Huixin Wan , Yao-Chang Xu , Hongping Yu , Ji Yue (Jeff) Zhang
IPC分类号： A61K31/397 , C07D471/04 , C07D519/00 , A61K31/437 , A61K31/496 , A61K31/5377 , A61K31/5513 , A61K45/06 , C07D491/107
CPC分类号： A61K31/551 , A61K31/437 , A61K31/4709 , A61K31/496 , A61K31/5377 , A61K31/5513 , A61K45/06 , C07D471/04 , C07D491/107 , C07D519/00
摘要： The invention relates to compounds of formula (I) and salts thereof: wherein the substituents are as defined in the specification; a compound of formula (I) for use in the treatment of the human or animal body, in particular with regard to c-Met tyrosine kinase mediated diseases or conditions; the use of a compound of formula (I) for manufacturing a medicament for the treatment of such diseases; pharmaceutical compositions comprising a compound of the formula (I), optionally in the presence of a combination partner, and processes for the preparation of a compound of formula (I).
摘要翻译：本发明涉及式（I）的化合物及其盐：其中取代基如说明书中所定义; 用于治疗人或动物体的式（I）化合物，特别是关于c-Met酪氨酸激酶介导的疾病或病症; 使用式（I）化合物制备用于治疗这些疾病的药物; 包含式（I）化合物，任选在组合配偶体存在下的药物组合物，以及制备式（I）化合物的方法。

4. 发明授权

US08507676B2 Heterocyclic oxime compounds 有权
标题翻译：杂环肟化合物
公开(公告)号：US08507676B2
公开(公告)日：2013-08-13
申请号：US13567386
申请日：2012-08-06
申请人： Miao Dai , Xingnian Fu , Feng He , Lei Jiang , Yue Li , Fang Liang , Lei Liu , Yuan Mi , Yao-Chang Xu , Guoliang Xun , Xiaoxia Yan , Zhengtian Yu , Ji Yue Zhang
发明人： Miao Dai , Xingnian Fu , Feng He , Lei Jiang , Yue Li , Fang Liang , Lei Liu , Yuan Mi , Yao-Chang Xu , Guoliang Xun , Xiaoxia Yan , Zhengtian Yu , Ji Yue Zhang
IPC分类号： C07D487/04 , C07D403/12 , A61K31/4985 , A61P35/00
CPC分类号： C07D471/04
摘要： The invention relates to compounds of formula (I) and salts thereof: wherein the substituents are as defined in the specification; a compound of formula (I) for use in the treatment of the human or animal body, in particular with regard to c-Met tyrosine kinase mediated diseases or conditions; the use of a compound of formula (I) for manufacturing a medicament for the treatment of such diseases; pharmaceutical compositions comprising a compound of the formula (I), optionally in the presence of a combination partner, and processes for the preparation of a compound of formula (I).
摘要翻译：本发明涉及式（I）的化合物及其盐：其中取代基如说明书中所定义; 用于治疗人或动物体的式（I）化合物，特别是关于c-Met酪氨酸激酶介导的疾病或病症; 使用式（I）化合物制备用于治疗这些疾病的药物; 包含式（I）化合物，任选在组合配偶体存在下的药物组合物，以及制备式（I）化合物的方法。

5. 发明授权

US08410264B2 Heterocyclic oxime compounds 有权
公开(公告)号：US08410264B2
公开(公告)日：2013-04-02
申请号：US12859653
申请日：2010-08-19
申请人： Miao Dai , Xingnian Fu , Feng He , Lei Jiang , Yue Li , Fang Liang , Lei Liu , Yuan Mi , Yao-chang Xu , Guoliang Xun , Xiaoxia Yan , Zhengtian Yu , Ji Yue Zhang
发明人： Miao Dai , Xingnian Fu , Feng He , Lei Jiang , Yue Li , Fang Liang , Lei Liu , Yuan Mi , Yao-chang Xu , Guoliang Xun , Xiaoxia Yan , Zhengtian Yu , Ji Yue Zhang
IPC分类号： C07D487/04 , A61K31/5025 , A61P35/00
CPC分类号： C07D471/04
摘要： The invention relates to compounds of formula (I) and salts thereof: wherein the substituents are as defined in the specification; a compound of formula (I) for use in the treatment of the human or animal body, in particular with regard to c-Met tyrosine kinase mediated diseases or conditions; the use of a compound of formula (I) for manufacturing a medicament for the treatment of such diseases; pharmaceutical compositions comprising a compound of the formula (I), optionally in the presence of a combination partner, and processes for the preparation of a compound of formula (I).

6. 发明授权

US09296754B2 Compounds and compositions for the treatment of parasitic diseases 有权
标题翻译：用于治疗寄生虫病的化合物和组合物
公开(公告)号：US09296754B2
公开(公告)日：2016-03-29
申请号：US14209850
申请日：2014-03-13
申请人： Fang Liang , Pranab Kumar Mishra , Valentina Molteni , Advait Suresh Nagle , Frantisek Supek , Liying Jocelyn Tan , Agnes Vidal
发明人： Fang Liang , Pranab Kumar Mishra , Valentina Molteni , Advait Suresh Nagle , Frantisek Supek , Liying Jocelyn Tan , Agnes Vidal
IPC分类号： A61K31/519 , C07D487/04 , A61K45/06
CPC分类号： C07D487/04 , A61K31/519 , A61K45/06 , Y02A50/409 , Y02A50/414 , Y02A50/415 , A61K2300/00
摘要： The present invention provides compounds of formula I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a parasite, such as Leishmaniasis, Human African Trypanosomiasis and Chagas disease.
摘要翻译：本发明提供式I化合物或其药学上可接受的盐，互变异构体或立体异构体，其中变量如本文所定义。本发明还提供包含这些化合物的药物组合物和使用这些化合物治疗，预防，抑制，改善或消除由寄生虫引起的疾病的病理和/或症状的方法，例如利什曼病，人非洲锥虫病和查加斯疾病。

7. 发明授权

US07846949B2 Compounds and compositions as LXR modulators 有权
标题翻译：化合物和组合物作为LXR调节剂
公开(公告)号：US07846949B2
公开(公告)日：2010-12-07
申请号：US10589410
申请日：2005-02-11
申请人： Valentina Molteni , Xiaolin Li , Fang Liang , Juliet Nabakka , Enrique Saez , John Wityak
发明人： Valentina Molteni , Xiaolin Li , Fang Liang , Juliet Nabakka , Enrique Saez , John Wityak
IPC分类号： A61K31/44 , A61K31/42 , A61K31/41 , C07D213/55 , C07D498/00 , C07D231/12 , C07C229/00
CPC分类号： C07C233/83 , C07C237/38 , C07C237/42 , C07C239/20 , C07C255/29 , C07C255/54 , C07C255/60 , C07C271/28 , C07C311/08 , C07C317/22 , C07C323/42 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07D239/26
摘要： The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of liver X receptors (LXRs).
摘要翻译：本发明提供化合物，包含这些化合物的药物组合物和使用这些化合物治疗或预防与肝脏X受体（LXR）活性相关的疾病或病症的方法。

8. 发明授权

US09700559B2 Compounds and compositions for the treatment of parasitic diseases 有权
公开(公告)号：US09700559B2
公开(公告)日：2017-07-11
申请号：US15051446
申请日：2016-02-23
申请人： Agnes Biggart , Fang Liang , Casey Jacob Nelson Mathison , Valentina Molteni , Advait Suresh Nagle , Frantisek Supek , Vince Yeh
发明人： Agnes Biggart , Fang Liang , Casey Jacob Nelson Mathison , Valentina Molteni , Advait Suresh Nagle , Frantisek Supek , Vince Yeh
IPC分类号： C07D487/04 , A61K31/519 , C07D519/00 , C07F5/02 , C07F7/08 , A61K31/5377 , A61K31/695
CPC分类号： A61K31/519 , A61K31/5377 , A61K31/695 , A61K45/06 , C07D487/04 , C07D519/00 , C07F5/027 , C07F7/0814
摘要： The present invention provides compounds of Formula A: or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a parasite, such as leishmaniasis, human African trypanosomiasis and Chagas disease.

9. 发明授权

US09186361B2 Compounds and compositions for the treatment of parasitic diseases 有权
标题翻译：用于治疗寄生虫病的化合物和组合物
公开(公告)号：US09186361B2
公开(公告)日：2015-11-17
申请号：US14209655
申请日：2014-03-13
申请人： Arnab Kumar Chatterjee , Fang Liang , Casey Jacob Nelson Mathison , Pranab Kumar Mishra , Valentina Molteni , Advait Suresh Nagle , Frantisek Supek , Liying Jocelyn Tan , Agnes Vidal
发明人： Arnab Kumar Chatterjee , Fang Liang , Casey Jacob Nelson Mathison , Pranab Kumar Mishra , Valentina Molteni , Advait Suresh Nagle , Frantisek Supek , Liying Jocelyn Tan , Agnes Vidal
IPC分类号： A01N43/42 , A61K31/44 , A61K31/5377 , A61K31/437 , A61K45/06 , C07D471/04 , C07D498/04
CPC分类号： A61K31/5377 , A61K31/437 , A61K45/06 , C07D471/04 , C07D498/04 , Y02A50/409 , Y02A50/414 , Y02A50/415
摘要： The present invention provides compounds of Formula I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a parasite, such as Leishmaniasis, Human African Trypanosomiasis and Chagas disease.
摘要翻译：本发明提供式I化合物或其药学上可接受的盐，互变异构体或立体异构体，其中变量如本文所定义。本发明还提供包含这些化合物的药物组合物和使用这些化合物治疗，预防，抑制，改善或消除由寄生虫引起的疾病的病理和/或症状的方法，例如利什曼病，人非洲锥虫病和查加斯疾病。

10. 发明授权

US06409474B1 Centrifugal pump formed by pressing and welding and its manufacturing process 有权
标题翻译：离心泵通过压制和焊接形成，其制造工艺
公开(公告)号：US06409474B1
公开(公告)日：2002-06-25
申请号：US09582689
申请日：2000-08-25
申请人： Fang Liang
发明人： Fang Liang
IPC分类号： F04D2954
CPC分类号： F04D29/4266
摘要： The invention relates to a centrifugal pump and it's manufacturing process, more particularly to a pump formed by pressing and welding metal sheet. In this invention, comprising a pump casing, an impeller, labyrinth ring supports, labyrinth rings, a real cover and a chassis, characterized in that the manufacturing process of said pump casing includes following steps: using a female mold made by wear-resisting metal, the female space in said female mold is a near 360° integrated spiral with radial expanded gradually shape and approximately semicircle cross section, using a male mold made by pressing deformable soft or elastic material, putting a tubular member with flange made by metal sheet between said molds, closing said molds, expanding said male mold made by soft or elastic material. Said tubular member will be expanded into a near 360° integrated spiral casing with radial expanded gradually shape and approximately semicircle cross section.
摘要翻译：本发明涉及一种离心泵及其制造方法，更具体地涉及通过压制和焊接金属板形成的泵。在本发明中，包括泵壳体，叶轮，迷宫环支撑件，迷宫环，真实盖和底盘，其特征在于，所述泵壳的制造过程包括以下步骤：使用由耐磨金属制成的阴模所述阴模中的雌性空间是近360°的一体化螺旋，径向膨胀逐渐形状和大致半圆形截面，使用通过压制可变形的软或弹性材料制成的阳模，将由金属片制成的凸缘的管状构件放在所述模具关闭所述模具，使由柔软或弹性材料制成的所述阳模膨胀。所述管状构件将被扩展成近似360°的集成螺旋壳体，其具有径向膨胀的逐渐形状和大致半圆形横截面。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式