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1. 发明申请

US20070134302A1 Antimicrobial substrates with peroxide treatment 审中-公开
标题翻译：用过氧化物处理的抗微生物底物
公开(公告)号：US20070134302A1
公开(公告)日：2007-06-14
申请号：US11301546
申请日：2005-12-13
申请人： David Koenig , Ali Yahiaoui , Alison Bagwell
发明人： David Koenig , Ali Yahiaoui , Alison Bagwell
IPC分类号： A61K9/70 , A61K33/40
CPC分类号： A61K33/40 , A01N25/34 , A61L2/23 , A61L2/232 , A01N59/00 , A01N33/12 , A01N25/22 , A01N25/10
摘要： An oxidizing antimicrobial treatment and products containing such treatment are described. The treatment involve, in part, preparing a substrate to accept an attachment of charged moieties, and a number of stabilized peroxide compounds on at least part of a surface of said substrate. When microbes, such as bacteria, having a net charge opposite to that of the charged moieties come in close proximity to the treated substrate surface, peroxide molecules from the substrate are activated and released to kill the microbes.
摘要翻译：描述了氧化性抗微生物处理和含有这种处理的产品。该处理部分地涉及制备底物以接受带电部分的附着物，以及在所述基材的至少部分表面上的多种稳定的过氧化物化合物。当具有与带电部分的净电荷相反的净电荷的微生物与处理的底物表面紧密接近时，来自底物的过氧化物分子被活化并释放以杀死微生物。

2. 发明申请

US20060140994A1 Application of an antimicrobial agent on an elastomeric article 审中-公开
标题翻译：抗微生物剂在弹性制品上的应用
公开(公告)号：US20060140994A1
公开(公告)日：2006-06-29
申请号：US11023201
申请日：2004-12-27
申请人： Alison Bagwell , David Koenig , Martin Shamis , Jali Williams
发明人： Alison Bagwell , David Koenig , Martin Shamis , Jali Williams
IPC分类号： A01N25/34
CPC分类号： C08J7/065 , C08J5/02 , C08J2321/02
摘要： An elastomeric article having reducing microbe affinity and transmission and methods for applying and immobilizing antimicrobial compounds to the elastomeric substrate surface are disclosed. The elastomeric article has a body formed of a natural or synthetic polymer latex having an outer surface and an inner surface. The body has a coating of an antimicrobial agent over at least a portion of said outer surface. The treatment involves applying according to either a spraying or dipping process an antimicrobial polymer or composition to a surface of the elastomeric substrate; binding the antimicrobial composition to the surface in a manner such that said treat antimicrobial coating passes either one or another or both versions of a zone of inhibition test, such test including: a) a dry-leaching or agar-plate-based contact test, according to AATCC 147 protocol, or b) a wet-leaching or dynamic shake flask test according to ASTM E-2149-01 protocol. The substrate is further subject to a rapid germicidal contact-transfer test of relatively short duration. The antimicrobial polymer can include an organosilane quaternary ammonium or a biguanide compound which can disrupt the ionic charges of microbial cellular membranes.
摘要翻译：公开了具有降低的微生物亲和性和透射性的弹性制品以及将抗微生物化合物施加和固定到弹性体基底表面上的方法。弹性制品具有由具有外表面和内表面的天然或合成聚合物胶乳形成的本体。身体在所述外表面的至少一部分上具有抗微生物剂的涂层。该处理包括根据喷雾或浸渍方法将抗微生物聚合物或组合物施用于弹性体基材的表面; 将抗微生物组合物以使得所述处理的抗微生物涂层通过抑制试验区的一种或两种或两种形式的方式将抗微生物组合物结合到表面，所述测试包括：a）干浸或琼脂平板接触试验，根据AATCC 147方案，或b）根据ASTM E-2149-01方案的湿浸或动态摇瓶试验。底物进一步经历相对较短持续时间的快速杀菌接触转移试验。抗微生物聚合物可以包括可以破坏微生物细胞膜的离子电荷的有机硅烷季铵或双胍化合物。

3. 发明申请

US20050147655A1 Non-leaching antimicrobial glove 审中-公开
标题翻译：非浸出抗菌手套
公开(公告)号：US20050147655A1
公开(公告)日：2005-07-07
申请号：US11057576
申请日：2005-02-14
申请人： Alison Bagwell , David Johnson , David Koenig , Martin Shamis , Wava Truscott
发明人： Alison Bagwell , David Johnson , David Koenig , Martin Shamis , Wava Truscott
IPC分类号： A41D19/00 , A61B19/04 , C08J7/04 , B32B5/02 , A61K9/70
CPC分类号： C08J7/047 , A41D19/0058 , A41D31/30 , A61B42/00 , C08J2321/00 , C08J2483/00 , Y10T428/31663 , Y10T442/2525
摘要： An elastomeric article having reducing microbe affinity and transmission is disclosed. The article has a coating of a hydrophobic, non-leaching antimicrobial polymer that is durably attached to an exterior surface, such that said antimicrobial polymer does not spontaneously migrate or is not removed from said exterior surface in the presence of aqueous substances, strong acids and bases, and organic solvents, and said antimicrobial polymer forms either a water-insoluable siloxane resin, or a covalently attached siloxane homopolymer, or a combination of both. The coated surface has a reduced affinity for aqueous-based substances and exhibits an enduring reduction in microbe affinity and transmission.
摘要翻译：公开了具有降低的微生物亲和性和透射性的弹性制品。所述制品具有耐久地连接到外表面的疏水性非浸出抗微生物聚合物的涂层，使得所述抗微生物聚合物在水性物质，强酸和强酸存在下不会自发迁移或不从所述外表面除去，碱和有机溶剂，并且所述抗微生物聚合物形成水不溶性硅氧烷树脂或共价连接的硅氧烷均聚物或两者的组合。涂覆的表面对水基物质的亲和力降低，并显示出微生物亲和力和透射性的持续降低。

4. 发明申请

US20070048344A1 Antimicrobial composition 审中-公开
标题翻译：抗微生物组成
公开(公告)号：US20070048344A1
公开(公告)日：2007-03-01
申请号：US11216800
申请日：2005-08-31
申请人： Ali Yahiaoui , Phillip Schorr , Douglas Hoffman , David Koenig , Anthony Spencer , Angela Dobson
发明人： Ali Yahiaoui , Phillip Schorr , Douglas Hoffman , David Koenig , Anthony Spencer , Angela Dobson
IPC分类号： A01N57/00 , A01N43/80 , A01N25/00 , A01N43/04
CPC分类号： C08K5/0058 , C08K5/31
摘要： An antimicrobial composition that involves a synergistic mixture in terms of active agents, of a primary antimicrobial agent, such as polyhexamethylene biguanide (PHMB), a secondary antimicrobial agent, and optionally an organic acid against various kinds of microbes is described. Various additional processing aids, such as alcohols and surfactants, may also be incorporated within the mixture. The composition allows one to use a significantly less concentration of individual constituent antimicrobial agents to achieve the same or a better degree of antimicrobial efficacy. The antimicrobial composition can be applied to the surface of almost any kind of substrate material, and can achieve a killing-efficacy of about 3 Log10 reduction in microbes within 30 minutes under ambient conditions.
摘要翻译：描述了关于活性剂，主要抗微生物剂如聚六亚甲基双胍（PHMB），二次抗微生物剂和任选的针对各种微生物的有机酸的协同混合物的抗微生物组合物。各种其它加工助剂，如醇和表面活性剂，也可以掺入混合物中。该组合物允许使用显着较少浓度的单个成分抗微生物剂以达到相同或更好程度的抗微生物效力。抗微生物组合物可以应用于几乎任何种类的底物材料的表面，并且可以在环境条件下在30分钟内实现微生物中约3log 10/10的还原的杀伤效力。

5. 发明授权

US07845351B2 Germicidal face mask 有权
标题翻译：杀菌面膜
公开(公告)号：US07845351B2
公开(公告)日：2010-12-07
申请号：US11215986
申请日：2005-08-31
申请人： Michael P. Mathis , Uyles Woodrow Bowen, Jr. , Eric Clayton Steindorf , Phillip A. Schorr , Angela Dobson , Ali Yahiaoui , Douglas R. Hoffman , David Koenig , Anthony Steve Spencer
发明人： Michael P. Mathis , Uyles Woodrow Bowen, Jr. , Eric Clayton Steindorf , Phillip A. Schorr , Angela Dobson , Ali Yahiaoui , Douglas R. Hoffman , David Koenig , Anthony Steve Spencer
IPC分类号： A62B18/00
CPC分类号： B32B5/26 , A41D13/11 , A41D31/0083 , A41D2400/34 , A62B23/025 , B32B5/022 , B32B2262/0276 , B32B2437/00
摘要： A face mask for reducing the amount of microbes to which a wearer is exposed is provided. The face mask includes a body portion that has an outer layer that has been treated with a germicidal agent in an effective amount. The layer may be a nonwoven fabric like a spunbond, meltblown or coform layer and may be a laminate of such layers. The face mask having such a germicidal treatment can result in a reduction in microbial activity as compared to another face mask, identical but for the germicidal agent.
摘要翻译：提供了一种用于减少穿着者暴露于其中的微生物数量的面罩。面罩包括具有有效量的用杀菌剂处理的外层的主体部分。该层可以是无纺织物，如纺粘，熔喷或共成型层，并且可以是这些层的层压体。具有这种杀菌处理的面罩可以导致与另一面罩相比的微生物活性降低，但是对于杀菌剂。

6. 发明申请

US20070048356A1 Antimicrobial treatment of nonwoven materials for infection control 审中-公开
标题翻译：用于感染控制的非织造材料的抗菌处理
公开(公告)号：US20070048356A1
公开(公告)日：2007-03-01
申请号：US11216341
申请日：2005-08-31
申请人： Phillip Schorr , Douglas Hoffman , David Koenig , Anthony Spencer , Ali Yahiaoui , Angela Dobson
发明人： Phillip Schorr , Douglas Hoffman , David Koenig , Anthony Spencer , Ali Yahiaoui , Angela Dobson
IPC分类号： A61K31/785 , A61K9/70
CPC分类号： A01N47/44 , C08K5/0058 , D06M15/564 , D06M15/61 , D06M16/00 , A01N25/10 , A01N25/34 , A01N33/12 , A01N37/02 , A01N37/04 , A01N37/36 , A01N59/00 , A01N2300/00 , C08L21/00
摘要： A material substrate having at least part of a surface treated with an antimicrobial composition is described. The antimicrobial composition exhibits at least a 3 log10 CFU reduction within a period of about 30 minutes after contact with various species of a broad spectrum of microorganisms. The substrate can be a nonwoven material that has good fluid barrier properties, which can be used in protective garments and sheets. Methods for manufacturing and imparting the antimicrobial treatment to the substrate are also provided.
摘要翻译：描述了具有用抗微生物组合物处理的表面的至少一部分的材料基材。抗微生物组合物在与各种各样的微生物接触后约30分钟内显示至少3log 10 CFU还原。基材可以是具有良好的流体阻隔性的非织造材料，其可用于防护服和片材。还提供了制造和赋予对基材的抗微生物处理的方法。

7. 发明申请

US20070048358A1 Antimicrobial substrates 审中-公开
标题翻译：抗微生物底物
公开(公告)号：US20070048358A1
公开(公告)日：2007-03-01
申请号：US11217013
申请日：2005-08-31
申请人： Phillip Schorr , Ali Yahiaoui , Douglas Hoffman , David Koenig , Anthony Spencer , Angela Dobson
发明人： Phillip Schorr , Ali Yahiaoui , Douglas Hoffman , David Koenig , Anthony Spencer , Angela Dobson
IPC分类号： A61K31/785 , A61K9/70
CPC分类号： A01N25/34 , A01N47/44 , A41D13/11 , A41D31/30 , A61B17/00 , A61K31/785 , A61L31/16 , A61L2300/416 , A61L2300/606 , A01N2300/00
摘要： A synergistic antimicrobial composition containing at least two kinds of antimicrobial agents, including poly-hexamethylene biguanide (PHMB), stably associated to a material substrate is described. The substrate can take the forms of an anti-infection face mask, medical devices, or surgical instruments.
摘要翻译：描述了与材料基底稳定相关的包含至少两种抗微生物剂（包括聚六亚甲基双胍（PHMB））的协同抗菌组合物。底物可以采取抗感染面罩，医疗装置或手术器械的形式。

8. 发明申请

US20070044801A1 Germicidal face mask 有权
标题翻译：杀菌面膜
公开(公告)号：US20070044801A1
公开(公告)日：2007-03-01
申请号：US11215986
申请日：2005-08-31
申请人： Michael Mathis , Uyles Bowen , Eric Steindorf , Phillip Schorr , Angela Dobson , Ali Yahiaoui , Douglas Hoffman , David Koenig , Anthony Spencer
发明人： Michael Mathis , Uyles Bowen , Eric Steindorf , Phillip Schorr , Angela Dobson , Ali Yahiaoui , Douglas Hoffman , David Koenig , Anthony Spencer
IPC分类号： A62B23/02
CPC分类号： B32B5/26 , A41D13/11 , A41D31/0083 , A41D2400/34 , A62B23/025 , B32B5/022 , B32B2262/0276 , B32B2437/00
摘要： A face mask for reducing the amount of microbes to which a wearer is exposed is provided. The face mask includes a body portion that has an outer layer that has been treated with a germicidal agent in an effective amount. The layer may be a nonwoven fabric like a spunbond, meltblown or coform layer and may be a laminate of such layers. The face mask having such a germicidal treatment can result in a reduction in microbial activity as compared to another face mask, identical but for the germicidal agent.
摘要翻译：提供了一种用于减少穿着者暴露于其中的微生物数量的面罩。面罩包括具有有效量的用杀菌剂处理的外层的主体部分。该层可以是无纺织物，如纺粘，熔喷或共成型层，并且可以是这些层的层压体。具有这种杀菌处理的面罩可以导致与另一面罩相比的微生物活性降低，但是对于杀菌剂。

9. 发明申请

US20060036222A1 Absorbent articles comprising a bodily exudate modifying agent and a skin care formulation 有权
标题翻译：包含身体渗出物改性剂和皮肤护理制剂的吸收制品
公开(公告)号：US20060036222A1
公开(公告)日：2006-02-16
申请号：US10915642
申请日：2004-08-10
申请人： Jason Cohen , David Koenig , Earl Brock , Stephen Baratian , Corey Cunningham , Stephen Baldwin
发明人： Jason Cohen , David Koenig , Earl Brock , Stephen Baratian , Corey Cunningham , Stephen Baldwin
IPC分类号： A61F13/15
CPC分类号： A61L15/18 , A61L15/20 , A61L15/38
摘要： Absorbent articles having enhanced absorption of bodily exudates are disclosed. The absorbent articles comprise a bodily exudate modifying agent and a skin care formulation. The bodily exudate modifying agent is capable of reducing the viscosity of bodily exudates such as feces and menses. The skin care formulation comprises a bodily exudate modifying agent neutralizer to neutralize the possible negative effects on skin barrier function caused by the bodily exudate modifying agents coming into direct contact with the wearer's skin.
摘要翻译：公开了具有增强的身体渗出物吸收的吸收制品。吸收制品包括身体渗出物改性剂和皮肤护理制剂。身体渗出物改性剂能够降低诸如粪便和月经之类的身体渗出物的粘度。皮肤护理制剂包括身体渗出物改性剂中和剂，以中和由与穿着者皮肤直接接触的身体渗出物改性剂引起的对皮肤屏障功能的可能的负面影响。

10. 发明申请

US20050201968A1 Processes for controlling microbial organic compound production 有权
标题翻译：控制微生物有机化合物生产的过程
公开(公告)号：US20050201968A1
公开(公告)日：2005-09-15
申请号：US11055503
申请日：2005-02-10
申请人： David Koenig , Bernard Minerath , Lindsay Gould
发明人： David Koenig , Bernard Minerath , Lindsay Gould
IPC分类号： A61L15/20 , A61L15/46 , A61K7/06 , A61K7/11 , A61K33/40
CPC分类号： A61L15/20 , A61L15/46 , A61L2300/11 , A61L2300/404 , A61L2300/622 , Y10S514/97
摘要： Processes for preparing products comprising an oxygen-generating additive for reducing the amount of skin irritation and inflamation and odor are disclosed. Specifically, products such as training pants and diapers are disclosed which contain a carbohydrate-hydrogen peroxide crystalline powder which, when wetted, produces a stream of oxygen which can be used by various bacteria on and near the wearer's skin during metabolism resulting in a significant decrease in the amount of volatile organic compounds produced by the bacteria during metabolism.
摘要翻译：公开了用于制备包含用于减少皮肤刺激和炎症和气味量的产氧添加剂的产品的方法。具体地说，公开了诸如训练裤和尿布的产品，其中含有碳水化合物 - 过氧化氢结晶粉末，其在润湿时产生氧气流，其可以在代谢期间在佩戴者皮肤上和附近由各种细菌使用，从而导致显着降低在代谢期间由细菌产生的挥发性有机化合物的量。

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