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1. 发明申请

US20090053383A1 ANGELICA KEISKEI TEA 审中-公开
公开(公告)号：US20090053383A1
公开(公告)日：2009-02-26
申请号：US12176088
申请日：2008-07-18
申请人： Hiroshi ENDO , Yasushi Hattori , Hitoshi Sakakibara , Katsumi Sugiyama , Yuko Asai , Satoko Motomura , Ikunoshin Kato
发明人： Hiroshi ENDO , Yasushi Hattori , Hitoshi Sakakibara , Katsumi Sugiyama , Yuko Asai , Satoko Motomura , Ikunoshin Kato
IPC分类号： A23F3/06 , A23F3/22
CPC分类号： A23F3/34
摘要： According to the present invention, there are provided kneading-free Angelica keiskei tea leaves obtainable by a treatment comprising a step for roast-heating a dried material of Angelica keiskei; an Angelica keiskei tea beverage produced by using the kneading-free Angelica keiskei tea leaves; and a process for producing thereof. The Angelica keiskei tea leaves are preferably heated at a heating temperature of 100° C. to 150° C. in the roast-heating treatment, and the dried material of Angelica keiskei to be subjected to the roast-heating is preferably obtained by drying in a dried system after blanching and has a moisture content of 20% or less. Further, according to the present invention, there is also provided an Angelica keiskei chalcone function-formulated beverage comprising formulated Angelica keiskei chalcones that are components specific to Angelica keiskei.
摘要翻译：根据本发明，提供了通过包括用于对当归keiskei的干燥材料进行烘烤的步骤的处理而获得的无捏合当归keiskei茶叶; 通过使用揉捏的当归keiskei茶叶生产的当归keiskei茶饮料; 及其制造方法。本发明的茶叶优选在烘烤加热处理中在100℃〜150℃的加热温度下进行加热，优选通过将烘烤后的干燥物干燥，漂白后的干燥体系，水分含量为20％以下。此外，根据本发明，还提供了包含作为当归keiskei特异性成分的配方的当归keiskei chalcones的当归keiskei查耳酮功能配方饮料。

2. 发明申请

US20100150955A1 Method of Producing Extract Derived From Lyophyllum Ulmarium 审中-公开
标题翻译：从叶绿素中提取提取物的方法
公开(公告)号：US20100150955A1
公开(公告)日：2010-06-17
申请号：US11990125
申请日：2006-08-02
申请人： Hiroshi Endo , Hitoshi Sakakibara , Yasushi Hattori , Kumi Sasaki , Ikunoshin Kato
发明人： Hiroshi Endo , Hitoshi Sakakibara , Yasushi Hattori , Kumi Sasaki , Ikunoshin Kato
IPC分类号： A61K36/06 , A23L1/28
CPC分类号： C07G17/00 , A23L33/105 , A61K36/07
摘要： A method of producing an extract derived from Lyophyllum ulmarium from fruiting body or mycelium of Lyophyllum ulmarium, wherein the method of producing an extract derived from Lyophyllum ulmarium uses an aqueous alkaline solvent as an extraction solvent; an extract derived from Lyophyllum ulmarium, obtainable by the method as defined above; and a food and a medicament each containing the extract.
摘要翻译：一种从柳叶from的子实体或菌丝体中生产由叶绿素藻提取物提取物的方法，其中生产由叶绿素藻提取物的提取物的方法使用碱性溶剂作为提取溶剂; 由通过上述方法获得的来自叶绿素藻的提取物; 以及各自含有提取物的食品和药物。

3. 发明授权

US07217817B1 Agarobiose-containing composition 失效
标题翻译：含琼脂二糖的组合物
公开(公告)号：US07217817B1
公开(公告)日：2007-05-15
申请号：US09979003
申请日：2000-05-08
申请人： Tatsuji Enoki , Hiroaki Sagawa , Takeshi Sakai , Haruo Oyashiki , Hitoshi Sakakibara , Kazuyori Ochiai , Ikunoshin Kato
发明人： Tatsuji Enoki , Hiroaki Sagawa , Takeshi Sakai , Haruo Oyashiki , Hitoshi Sakakibara , Kazuyori Ochiai , Ikunoshin Kato
IPC分类号： C08B37/12 , A61K31/729
CPC分类号： A23G1/48 , A21D2/18 , A23C20/025 , A23F3/163 , A23F3/405 , A23G1/40 , A23G3/346 , A23G3/42 , A23G3/48 , A23G2200/06 , A23L2/52 , A23L2/60 , A23L5/00 , A23L7/00 , A23L7/109 , A23L13/42 , A23L13/428 , A23L13/65 , A23L17/60 , A23L17/70 , A23L21/00 , A23L21/15 , A23L23/00 , A23L27/33 , A23L29/256 , A23L29/30 , A23V2002/00 , C12G3/06 , Y02P20/582 , A23V2250/2124 , A23V2250/704 , A23V2250/708 , A23V2250/032 , A23V2250/0638 , A23V2250/0626 , A23V2250/606
摘要： A material containing agarobiose; a method for preparing the material; and a food, a drink or a seasoning using the material, which is tasty and has the effect of alleviating a stimulant taste and of enhancing the depth of sweetness.
摘要翻译：含有琼脂二糖的物质一种制备该材料的方法; 以及使用该材料的食物，饮料或调味料，其是美味的并且具有减轻兴奋剂味道和增强甜度深度的作用。

4. 发明授权

US07498357B2 Chalcone compounds 失效
标题翻译：查耳酮化合物
公开(公告)号：US07498357B2
公开(公告)日：2009-03-03
申请号：US10581034
申请日：2004-12-01
申请人： Hiromu Ohnogi , Katsumi Sugiyama , Tatsuji Enoki , Eiji Kobayashi , Hiroaki Sagawa , Ikunoshin Kato
发明人： Hiromu Ohnogi , Katsumi Sugiyama , Tatsuji Enoki , Eiji Kobayashi , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号： A61K31/343 , C07D307/80
CPC分类号： C07D493/08 , A23K20/121 , A23L33/10 , C07C49/835 , C07C49/84 , C07C409/08 , C07D307/80
摘要： The present invention provides a novel chalcone compound, its derivative or a salt thereof, each having a suppressive action of NO production or an inhibitory action of aldose reductase. In addition, the present invention provides a medicament, a food, a beverage or a feed having a therapeutic or prophylactic effect for a disease showing sensitivity to the compound, by utilizing the physiological actions of the compound.
摘要翻译：本发明提供了具有NO产生抑制作用或醛糖还原酶抑制作用的新型查耳酮化合物及其衍生物或其盐。此外，本发明通过利用化合物的生理作用，提供对化合物显示敏感性的疾病具有治疗或预防作用的药物，食品，饮料或饲料。

5. 发明申请

US20070092587A1 Extract from plant of japanese parsley family and process for producing the same 审中-公开
标题翻译：从日本欧芹系列植物提取物及其生产方法
公开(公告)号：US20070092587A1
公开(公告)日：2007-04-26
申请号：US10561431
申请日：2004-06-18
申请人： Hiromu Ohnogi , Katsumi Sugiyama , Nobuko Muraki , Tatsuji Enoki , Hiroaki Sagawa , Ikunoshin Kato
发明人： Hiromu Ohnogi , Katsumi Sugiyama , Nobuko Muraki , Tatsuji Enoki , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号： A61K36/232
CPC分类号： A61K36/232 , A23L2/02 , A23V2002/00 , A23V2250/21 , A23V2200/328
摘要： The present invention provides an extract obtainable by extracting a plant belonging to Umbelliferae, or a processed product thereof, with a water-containing alcohol; a process for preparing the extract; a therapeutic agent or prophylactic agent for a disease accompanying an abnormality in an amount of insulin or insulin response and/or diabetic complications, characterized in that the therapeutic agent or prophylactic agent comprises as an effective ingredient the extract as defined above; an agent for an insulin-mimetic action, characterized in that the agent comprises as an effective ingredient the extract as defined above; a food, beverage or feed, comprising the extract as defined above; an agent for enhancing glucose uptake into a cell, characterized in that the agent comprises as an effective ingredient the extract as defined above; to an agent for inducing differentiation into an adipocyte, characterized in that the agent comprises as an effective ingredient the extract as defined above; and an inhibitory agent for aldose reductase, characterized in that the agent comprises as an effective ingredient the extract as define above.
摘要翻译：本发明提供通过用含水醇提取属于伞形赤霉属的植物或其加工产物而获得的提取物; 一种制备提取物的方法; 用于伴随胰岛素或胰岛素反应量和/或糖尿病并发症的异常的疾病的治疗剂或预防剂，其特征在于所述治疗剂或预防剂包含作为有效成分的上述提取物; 用于胰岛素模拟作用的药剂，其特征在于所述药剂包含如上所定义的提取物作为有效成分; 包含上述提取物的食品，饮料或饲料; 用于增强葡萄糖摄入细胞的药剂，其特征在于所述药剂包含如上所定义的提取物作为有效成分; 涉及诱导分化为脂肪细胞的药剂，其特征在于所述药剂包含如上所定义的提取物作为有效成分; 以及醛糖还原酶抑制剂，其特征在于，所述药剂含有作为有效成分的上述定义的提取物。

6. 发明申请

US20070202238A1 Agarobiose-containing composition 审中-公开
公开(公告)号：US20070202238A1
公开(公告)日：2007-08-30
申请号：US11785971
申请日：2007-04-23
申请人： Tatsuji Enoki , Hiroaki Sagawa , Takeshi Sakai , Haruo Oyashiki , Hitoshi Sakakibara , Kazuyori Ochiai , Ikunoshin Kato
发明人： Tatsuji Enoki , Hiroaki Sagawa , Takeshi Sakai , Haruo Oyashiki , Hitoshi Sakakibara , Kazuyori Ochiai , Ikunoshin Kato
IPC分类号： A23L2/00
CPC分类号： A23G1/48 , A21D2/18 , A23C20/025 , A23F3/163 , A23F3/405 , A23G1/40 , A23G3/346 , A23G3/42 , A23G3/48 , A23G2200/06 , A23L2/52 , A23L2/60 , A23L5/00 , A23L7/00 , A23L7/109 , A23L13/42 , A23L13/428 , A23L13/65 , A23L17/60 , A23L17/70 , A23L21/00 , A23L21/15 , A23L23/00 , A23L27/33 , A23L29/256 , A23L29/30 , A23V2002/00 , C12G3/06 , Y02P20/582 , A23V2250/2124 , A23V2250/704 , A23V2250/708 , A23V2250/032 , A23V2250/0638 , A23V2250/0626 , A23V2250/606
摘要： A material containing agarobiose; a method for preparing the material; and a food, a drink or a seasoning using the material, which is tasty and has the effect of alleviating a stimulant taste and of enhancing the depth of sweetness.

7. 发明申请

US20080008773A1 Food beverage or feed for the promotion of osteogenesis comprising umbelliferae, liliaceae or compositae plant species 审中-公开
标题翻译：用于促进成骨的食物饮料或饲料，包括伞形花序，百合科或合成植物物种
公开(公告)号：US20080008773A1
公开(公告)日：2008-01-10
申请号：US11819441
申请日：2007-06-27
申请人： Hiromu Ohnogi , Katsumi Sugiyama , Nobuko Muraki , Hiroaki Sagawa , Ikunoshin Kato
发明人： Hiromu Ohnogi , Katsumi Sugiyama , Nobuko Muraki , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号： A61K36/886 , A61K36/00 , A61P19/00 , A61K36/28
CPC分类号： C07D311/80 , A23K20/121 , A23L33/105 , A23V2002/00 , A61K31/353 , A61K36/23 , A61K36/232 , A61K36/282 , A61K36/8967 , A23V2200/306 , A23V2250/21
摘要： The present invention relates to a therapeutic agent or prophylactic agent for a disease requiring promotion of osteogenesis or enhancement of bone morphogenetic protein production, an agent for promotion of osteogenesis or an agent for enhancement of bone morphogenetic protein production, and a food, beverage or feed for promotion of osteogenesis or enhancement of bone morphogenetic protein production, characterized in that each comprises as an effective ingredient a processed product derived from a plant. Also, the present invention relates to a method for measuring an enhancing action for bone morphogenetic protein production, a method for screening a substance having an enhancing action for bone morphogenetic protein production, and a method for preparing a substance having an enhancing action for bone morphogenetic protein production, each method using a specified cell.
摘要翻译：本发明涉及需要促进骨形成发生或增强骨形态发生蛋白质生成的疾病的治疗剂或预防剂，促进成骨的药剂或增强骨形态发生蛋白质生产的药剂，以及食品，饮料或饲料用于促进成骨或增强骨形态发生蛋白质的生成，其特征在于，每种都包含作为有效成分的来自植物的加工产品。另外，本发明涉及骨形态发生蛋白质生成增强作用的测定方法，骨形态发生蛋白质生成增强作用物质的筛选方法以及骨形态发生增强作用物质的制备方法蛋白质生产，每种方法使用指定的细胞。

8. 发明申请

US20060039998A1 Remedies 审中-公开
标题翻译：补救措施
公开(公告)号：US20060039998A1
公开(公告)日：2006-02-23
申请号：US10529860
申请日：2003-09-29
申请人： Hiromu Ohnogi , Katsumi Sugiyama , Nobuko Muraki , Hiroaki Sagawa , Ikunoshin Kato
发明人： Hiromu Ohnogi , Katsumi Sugiyama , Nobuko Muraki , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号： A61K36/282 , A61K36/232 , A61K36/896 , A61K36/886
CPC分类号： C07D311/80 , A23K20/121 , A23L33/105 , A23V2002/00 , A61K31/353 , A61K36/23 , A61K36/232 , A61K36/282 , A61K36/8967 , A23V2200/306 , A23V2250/21
摘要： The present invention relates to a therapeutic agent or prophylactic agent for a disease requiring promotion of osteogenesis or enhancement of bone morphogenetic protein production, an agent for promotion of osteogenesis or an agent for enhancement of bone morphogenetic protein production, and a food, beverage or feed for promotion of osteogenesis or enhancement of bone morphogenetic protein production, characterized in that each comprises as an effective ingredient a processed product derived from a plant. Also, the present invention relates to a method for measuring an enhancing action for bone morphogenetic protein production, a method for screening a substance having an enhancing action for bone morphogenetic protein production, and a method for preparing a substance having an enhancing action for bone morphogenetic protein production, each method using a specified cell.
摘要翻译：本发明涉及需要促进骨形成发生或增强骨形态发生蛋白质生成的疾病的治疗剂或预防剂，促进成骨的药剂或增强骨形态发生蛋白质生产的药剂，以及食品，饮料或饲料用于促进成骨或增强骨形态发生蛋白质的生成，其特征在于，每种都包含作为有效成分的来自植物的加工产品。另外，本发明涉及骨形态发生蛋白质生成增强作用的测定方法，骨形态发生蛋白质生成增强作用物质的筛选方法以及骨形态发生增强作用物质的制备方法蛋白质生产，每种方法使用指定的细胞。

9. 发明申请

US20050272809A1 Remedies 失效
标题翻译：补救措施
公开(公告)号：US20050272809A1
公开(公告)日：2005-12-08
申请号：US10529859
申请日：2003-09-29
申请人： Hiromu Ohnogi , Katsumi Sugiyama , Nobuko Muraki , Tatsuji Enoki , Hiroaki Sagawa , Ikunoshin Kato
发明人： Hiromu Ohnogi , Katsumi Sugiyama , Nobuko Muraki , Tatsuji Enoki , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号： A23K1/16 , A23L1/30 , A61P25/00 , A61P43/00 , C07D311/58 , C07D311/80 , A61K31/353 , C07D311/76
CPC分类号： C07D311/80 , A23K20/121 , A23L33/10 , C07D311/58
摘要： The present invention relates to a novel chalcone compound represented by the following general formula: wherein R1 and R2 are taken together with the carbon atom to which they are bound, respectively, to form a hydroxydimethyl hexane ring, or where R1 is a hydroxyl group, R2 is an isohexenyl group, a derivative thereof, or a salt thereof. Also, the present invention relates to a therapeutic agent or prophylactic agent for a disease requiring neuronal protection, suppression for nitrogen monoxide (NO) production, inhibition for aldose reductase or suppression for interleukin production, and a food, beverage or feed for treatment or prevention of the above-mentioned disease, characterized in that each comprises the above-mentioned compound as an effective ingredient.
摘要翻译：本发明涉及由以下通式表示的新型查耳酮化合物：其中R 1和R 2分别与它们所结合的碳原子一起连接，以形成羟基二甲基己烷环，或其中R 1是羟基，R 2是异己烯基，其衍生物或其盐。此外，本发明涉及需要神经元保护，抑制一氧化氮（NO）产生，抑制醛糖还原酶或抑制白介素产生的疾病的治疗剂或预防剂，以及用于治疗或预防的食品，饮料或饲料的上述疾病，其特征在于，每种都包含上述化合物作为有效成分。

10. 发明申请

US20050250715A1 Remedy 审中-公开
标题翻译：补救
公开(公告)号：US20050250715A1
公开(公告)日：2005-11-10
申请号：US10521447
申请日：2003-07-17
申请人： Hiromu Ohnogi , Katsumi Sugiyama , Hiroaki Sagawa , Ikunoshin Kato
发明人： Hiromu Ohnogi , Katsumi Sugiyama , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号： A23L1/30 , A61K31/56 , A61K31/704 , A61P9/00 , A61P25/00 , A61P27/02 , A61P35/00 , A61P43/00 , C07H15/256 , C07J63/00
CPC分类号： C07J63/00 , A23L33/10 , A61K31/56 , A61K31/704 , C07H15/256 , A61K2300/00
摘要： The present invention relates to a therapeutic agent or prophylactic agent for a disease requiring enhancement of nerve growth factor (NGF) production upon treatment or prevention, an enhancing agent for nerve growth factor production, and a food, beverage or feed for enhancing nerve growth factor production, characterized in that each comprises as an effective ingredient a compound selected from the group consisting of soyasaponin compounds, soyasapogenin compounds, glycyrrhizin and salts thereof. In addition, the present invention relates to a novel soyasaponin compound and a novel soyasapogenin compound, having an action for enhancement of NGF production.
摘要翻译：本发明涉及治疗或预防需要增强神经生长因子（NGF）产生的疾病的治疗剂或预防剂，用于神经生长因子产生的增强剂，以及用于增强神经生长因子的食品，饮料或饲料其特征在于，各自包含选自由大豆皂角苷化合物，大豆皂草苷化合物，甘草甜素及其盐组成的组的有效成分。此外，本发明涉及一种新的大豆皂草素化合物和具有增强NGF产生作用的新型大豆皂草配基化合物。

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