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    • 6. 发明授权
    • Ophthalmic compositions for soft contact lens, method of enhancing wettability of soft contact lens and method of inhibiting terpenoid adsorption
    • 用于软性隐形眼镜的眼用组合物,增强软性隐形眼镜的润湿性的方法和抑制萜类吸附的方法
    • US06479556B2
    • 2002-11-12
    • US09931764
    • 2001-08-20
    • Koji DoiHisayuki NakayamaTakuya NakajimaNoriko Sakai
    • Koji DoiHisayuki NakayamaTakuya NakajimaNoriko Sakai
    • A01N3100
    • A61K31/125A61K9/0048A61K31/045Y10S514/912
    • The present invention provides an ophthalmic composition for soft contact lenses (SCL), which contains a terpenoid as an active ingredient, an ophthalmic composition for SCL, which contains polyoxyethylene sorbitan ester, a method of enhancing the wettability of soft contact lenses, which comprises bringing terpenoid into contact with SCL and a method of inhibiting adsorption of terpenoid onto SCL, which comprises adding polyoxyethylene sorbitan ester to an ophthalmic composition containing a terpenoid. The ophthalmic composition containing a terpenoid improves, for example, the wettability of SCL, thereby to inhibit decrease in the water content of SCL. As a result, it can inhibit a dry feeling and an uncomfortable feeling during wearing SCL and is useful for enhancing the wettability of SCL. Further, addition of polyoxyethylene sorbitan ester leads to the inhibition of adsorption of terpenoid onto SCL.
    • 本发明提供一种含有萜类化合物作为活性成分的软性隐形眼镜(SCL)用眼用组合物,含有聚氧乙烯山梨聚糖酯的SCL用眼用组合物,增强软性隐形眼镜的润湿性的方法, 萜类化合物与SCL接触以及抑制萜类化合物在SCL上吸附的方法,其包括将聚氧乙烯失水山梨醇酯加入到含有萜类化合物的眼用组合物中。 包含萜类化合物的眼用组合物改善了例如SCL的润湿性,从而抑制了SCL的水分含量的降低。 结果,可以抑制穿着SCL时的干燥感和不适感,并且对于提高SCL的润湿性是有用的。 此外,加入聚氧乙烯脱水山梨糖醇酯导致抑制萜类化合物在SCL上的吸附。
    • 10. 发明授权
    • Agent for contact lenses
    • 隐形眼镜代理
    • US5994405A
    • 1999-11-30
    • US10798
    • 1998-01-22
    • Koji DoiShuuichi NishihataTakuya Nakajima
    • Koji DoiShuuichi NishihataTakuya Nakajima
    • A01N37/18A61L12/14A61K31/16
    • A61L12/14A01N37/18Y10S514/912
    • An agent for contact lenses, comprising chloroacetamide. According to the present invention, chloroacetamide, which is the bacteriocidal component to be contained, is scarcely adsorbed not only to hard contact lenses and gas-permeable hard contact lenses, but also to soft contact lenses, and even if adsorbed, moreover, chloroacetamide is quickly released and is not accumulated on the contact lens to a greater extent. The inventive agent containing, in addition to chloroacetamide, sodium lauryl sulfate shows more superior bacteriocidal effect and cleaning effect. Therefore, the present invention provides an agent for contact lenses having superior bacteriocidal effect and cleaning effect, which can be used safely and with ease for various contact lenses inclusive of soft contact lenses.
    • 隐形眼镜剂,包含氯乙酰胺。 根据本发明,作为所含有的杀菌成分的氯乙酰胺不仅难以吸附在硬性隐形眼镜和透气性硬隐形眼镜上,而且也被吸附在软性隐形眼镜上,而且氯乙酰胺是 迅速释放并且不会在隐形眼镜上积累更多的程度。 含有氯乙酰胺十二烷基硫酸钠的本发明剂具有更优异的杀菌效果和清洁效果。 因此,本发明提供了具有优良杀菌效果和清洁效果的隐形眼镜剂,其可以安全地并且容易地用于包括软性隐形眼镜的各种隐形眼镜。