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1. 发明授权

US08524086B2 Fluid purification system 有权
公开(公告)号：US08524086B2
公开(公告)日：2013-09-03
申请号：US13068038
申请日：2011-04-29
申请人： Richard B. Peterson , James R. Curtis
发明人： Richard B. Peterson , James R. Curtis
IPC分类号： A61L2/04 , A61L2/00 , B01D61/02 , B01D61/14 , B01D61/28 , C02F1/20 , C02F1/44
CPC分类号： A61M1/1686 , A61M1/1658 , A61M1/1672 , A61M2205/75 , B01D61/025 , B01D61/08 , B01D61/145 , B01D61/18 , B01D61/30 , B01D61/58 , B01D2311/04 , B01D2311/06 , B01D2311/25 , C02F1/001 , C02F1/02 , C02F1/20 , C02F1/283 , C02F1/441 , C02F1/444 , C02F9/005 , C02F2103/026 , C02F2209/005 , C02F2209/006 , C02F2209/03 , C02F2301/043 , C02F2301/046 , C02F2303/04 , F24H1/121 , B01D2311/2649 , B01D2311/103 , B01D2311/2653
摘要： Certain disclosed embodiments concern systems and methods of preparing dialysate for use in a home dialysis system that is compact and light-weight relative to existing systems and consumes relatively low amounts of energy. The method includes coupling a household water stream to a dialysis system; filtering the water stream; heating the water stream to at least about 138 degrees Celsius in a non-batch process to produce a heated water stream; maintaining the heated water stream at or above at least about 138 degrees Celsius for at least about two seconds; cooling the heated water stream to produce a cooled water stream; ultrafiltering the cooled water stream; and mixing dialysate components into the cooled water stream in a non-batch process.

2. 发明授权

US08501009B2 Fluid purification system 有权
标题翻译：流体净化系统
公开(公告)号：US08501009B2
公开(公告)日：2013-08-06
申请号：US12795382
申请日：2010-06-07
申请人： Richard B. Peterson , James R. Curtis , Hailei Wang , Robbie Ingram-Goble , Luke W. Fisher , Anna E. Garrison
发明人： Richard B. Peterson , James R. Curtis , Hailei Wang , Robbie Ingram-Goble , Luke W. Fisher , Anna E. Garrison
IPC分类号： B01D61/26 , C02F1/44 , C02F1/02
CPC分类号： A61M1/1686 , A61M1/1658 , A61M1/1672 , A61M2205/75 , B01D61/025 , B01D61/08 , B01D61/145 , B01D61/18 , B01D61/30 , B01D61/58 , B01D2311/04 , B01D2311/06 , B01D2311/25 , C02F1/001 , C02F1/02 , C02F1/20 , C02F1/283 , C02F1/441 , C02F1/444 , C02F9/005 , C02F2103/026 , C02F2209/005 , C02F2209/006 , C02F2209/03 , C02F2301/043 , C02F2301/046 , C02F2303/04 , F24H1/121 , B01D2311/2649 , B01D2311/103 , B01D2311/2653
摘要： Disclosed are systems and methods of preparing dialysate for use in a home dialysis system that is compact and light-weight relative to existing systems and consumes relatively low amounts of energy. The method includes coupling a household water stream to a dialysis system; filtering the water stream; heating the water stream to at least about 138 degrees Celsius in a non-batch process to produce a heated water stream; maintaining the heated water stream at or above at least about 138 degrees Celsius for at least about two seconds; cooling the heated water stream to produce a cooled water stream; ultrafiltering the cooled water stream; and mixing dialysate components into the cooled water stream in a non-batch process.
摘要翻译：公开了用于家庭透析系统中使用的透析液的系统和方法，其相对于现有系统而言紧凑且重量轻并且消耗相对低的能量。该方法包括将家用水流连接到透析系统; 过滤水流; 在非分批方法中将水流加热到至少约138摄氏度以产生加热的水流; 将加热的水流维持在至少约138摄氏度以上至少约2秒; 冷却加热的水流以产生冷却的水流; 超滤冷却水流; 并以非分批方法将透析液组分混合到冷却水流中。

3. 发明授权

US08801922B2 Dialysis system 有权
标题翻译：透析系统
公开(公告)号：US08801922B2
公开(公告)日：2014-08-12
申请号：US12795444
申请日：2010-06-07
申请人： Julie S. Wrazel , James R. Curtis , Ladislaus Nonn , Richard B. Peterson , Hailei Wang , Robbie Ingram-Goble , Luke W. Fisher , Anna E. Garrison , M. Kevin Drost , Goran Jovanovic , Richard Todd Miller , Bruce W. Johnson , Alana Warner-Tuhy , Eric K. Anderson
发明人： Julie S. Wrazel , James R. Curtis , Ladislaus Nonn , Richard B. Peterson , Hailei Wang , Robbie Ingram-Goble , Luke W. Fisher , Anna E. Garrison , M. Kevin Drost , Goran Jovanovic , Richard Todd Miller , Bruce W. Johnson , Alana Warner-Tuhy , Eric K. Anderson
IPC分类号： B01D61/32 , B01D61/28 , B01D61/30 , A61M1/16 , A61M1/14 , C02F1/02 , C02F1/44 , C02F103/02 , F28D21/00
CPC分类号： A61M1/1686 , A61M1/14 , A61M1/16 , A61M1/1656 , A61M1/1662 , A61M1/1666 , A61M2205/0244 , B01D63/085 , B01D2313/08 , C02F1/02 , C02F1/20 , C02F1/283 , C02F1/44 , C02F1/441 , C02F1/444 , C02F9/005 , C02F2103/026 , C02F2209/03 , C02F2209/05 , C02F2303/04 , F24H1/121 , F24H9/0021 , F28D7/12 , F28D2021/005 , F28F3/08 , F28F2260/02 , Y10T29/494
摘要： A dialysis system includes a filtration system capable of filtering a water stream, a water purification system capable of purifying said water stream in a non-batch process, a mixing system capable of producing a stream of dialysate from mixing one or more dialysate components with the water stream in a non-batch process, and a dialyzer system. The dialyzer may be a microfluidic dialyzer capable of being fluidly coupled to the stream of dialysate and a blood stream.
摘要翻译：透析系统包括能够过滤水流的过滤系统，能够以非分批方法净化所述水流的水净化系统，能够通过将一种或多种透析液组分与非批次过程中的水流，以及透析器系统。透析器可以是能够流体耦合到透析液流和血流的微流体透析器。

4. 发明申请

US20110300231A1 Fluid purification system 有权
标题翻译：流体净化系统
公开(公告)号：US20110300231A1
公开(公告)日：2011-12-08
申请号：US13068038
申请日：2011-05-02
申请人： Richard B. Peterson , James R. Curtis
发明人： Richard B. Peterson , James R. Curtis
IPC分类号： A61K33/00 , A61L2/00 , C02F1/44 , C02F1/20 , B01D61/26 , B01D61/28
CPC分类号： A61M1/1686 , A61M1/1658 , A61M1/1672 , A61M2205/75 , B01D61/025 , B01D61/08 , B01D61/145 , B01D61/18 , B01D61/30 , B01D61/58 , B01D2311/04 , B01D2311/06 , B01D2311/25 , C02F1/001 , C02F1/02 , C02F1/20 , C02F1/283 , C02F1/441 , C02F1/444 , C02F9/005 , C02F2103/026 , C02F2209/005 , C02F2209/006 , C02F2209/03 , C02F2301/043 , C02F2301/046 , C02F2303/04 , F24H1/121 , B01D2311/2649 , B01D2311/103 , B01D2311/2653
摘要： Certain disclosed embodiments concern systems and methods of preparing dialysate for use in a home dialysis system that is compact and light-weight relative to existing systems and consumes relatively low amounts of energy. The method includes coupling a household water stream to a dialysis system; filtering the water stream; heating the water stream to at least about 138 degrees Celsius in a non-batch process to produce a heated water stream; maintaining the heated water stream at or above at least about 138 degrees Celsius for at least about two seconds; cooling the heated water stream to produce a cooled water stream; ultrafiltering the cooled water stream; and mixing dialysate components into the cooled water stream in a non-batch process.
摘要翻译：某些公开的实施方案涉及制备在家用透析系统中使用的透析液的系统和方法，该系统和方法相对于现有系统而言紧凑且重量轻并且消耗相对低的能量。该方法包括将家用水流连接到透析系统; 过滤水流; 在非分批方法中将水流加热到至少约138摄氏度以产生加热的水流; 将加热的水流维持在至少约138摄氏度以上至少约2秒; 冷却加热的水流以产生冷却的水流; 超滤冷却水流; 并以非分批方法将透析液组分混合到冷却水流中。

5. 发明申请

US20130327715A1 FLUID PURIFICATION SYSTEM 有权
公开(公告)号：US20130327715A1
公开(公告)日：2013-12-12
申请号：US13965720
申请日：2013-08-13
申请人： Richard B. Peterson , James R. Curtis
发明人： Richard B. Peterson , James R. Curtis
IPC分类号： B01D61/30 , C02F9/00
CPC分类号： A61M1/1686 , A61M1/1658 , A61M1/1672 , A61M2205/75 , B01D61/025 , B01D61/08 , B01D61/145 , B01D61/18 , B01D61/30 , B01D61/58 , B01D2311/04 , B01D2311/06 , B01D2311/25 , C02F1/001 , C02F1/02 , C02F1/20 , C02F1/283 , C02F1/441 , C02F1/444 , C02F9/005 , C02F2103/026 , C02F2209/005 , C02F2209/006 , C02F2209/03 , C02F2301/043 , C02F2301/046 , C02F2303/04 , F24H1/121 , B01D2311/2649 , B01D2311/103 , B01D2311/2653
摘要： Certain disclosed embodiments concern systems and methods of preparing dialysate for use in a home dialysis system that is compact and light-weight relative to existing systems and consumes relatively low amounts of energy. The method includes coupling a household water stream to a dialysis system; filtering the water stream; heating the water stream to at least about 138 degrees Celsius in a non-batch process to produce a heated water stream; maintaining the heated water stream at or above at least about 138 degrees Celsius for at least about two seconds; cooling the heated water stream to produce a cooled water stream; ultrafiltering the cooled water stream; and mixing dialysate components into the cooled water stream in a non-batch process.

6. 发明申请

US20110300230A1 FLUID PURIFICATION SYSTEM 有权
标题翻译：流体净化系统
公开(公告)号：US20110300230A1
公开(公告)日：2011-12-08
申请号：US12795382
申请日：2010-06-07
申请人： Richard B. Peterson , James R. Curtis , Hailei Wang , Robbie Ingram-Goble , Luke W. Fisher , Anna E. Garrison
发明人： Richard B. Peterson , James R. Curtis , Hailei Wang , Robbie Ingram-Goble , Luke W. Fisher , Anna E. Garrison
IPC分类号： A61K33/00 , C02F1/44 , C02F1/02
CPC分类号： A61M1/1686 , A61M1/1658 , A61M1/1672 , A61M2205/75 , B01D61/025 , B01D61/08 , B01D61/145 , B01D61/18 , B01D61/30 , B01D61/58 , B01D2311/04 , B01D2311/06 , B01D2311/25 , C02F1/001 , C02F1/02 , C02F1/20 , C02F1/283 , C02F1/441 , C02F1/444 , C02F9/005 , C02F2103/026 , C02F2209/005 , C02F2209/006 , C02F2209/03 , C02F2301/043 , C02F2301/046 , C02F2303/04 , F24H1/121 , B01D2311/2649 , B01D2311/103 , B01D2311/2653
摘要： Disclosed are systems and methods of preparing dialysate for use in a home dialysis system that is compact and light-weight relative to existing systems and consumes relatively low amounts of energy. The method includes coupling a household water stream to a dialysis system; filtering the water stream; heating the water stream to at least about 138 degrees Celsius in a non-batch process to produce a heated water stream; maintaining the heated water stream at or above at least about 138 degrees Celsius for at least about two seconds; cooling the heated water stream to produce a cooled water stream; ultrafiltering the cooled water stream; and mixing dialysate components into the cooled water stream in a non-batch process.
摘要翻译：公开了用于家庭透析系统中使用的透析液的系统和方法，其相对于现有系统而言紧凑且重量轻并且消耗相对低的能量。该方法包括将家用水流连接到透析系统; 过滤水流; 在非分批方法中将水流加热到至少约138摄氏度以产生加热的水流; 将加热的水流维持在至少约138摄氏度以上至少约2秒; 冷却加热的水流以产生冷却的水流; 超滤冷却水流; 并以非分批方法将透析液组分混合到冷却水流中。

7. 发明申请

US20100326916A1 DIALYSIS SYSTEM 有权
标题翻译： DIALYSIS系统
公开(公告)号：US20100326916A1
公开(公告)日：2010-12-30
申请号：US12795444
申请日：2010-06-07
申请人： Julie Wrazel , James R. Curtis , Ladislaus Nonn , Richard B. Peterson , Hailei Wang , Robbie Ingram-Goble , Luke W. Fisher , Anna E. Garrison , M. Kevin Drost , Goran Jovanovic , Richard Todd Miller , Bruce W. Johnson , Alana Warner-Tuhy , Eric K. Anderson
发明人： Julie Wrazel , James R. Curtis , Ladislaus Nonn , Richard B. Peterson , Hailei Wang , Robbie Ingram-Goble , Luke W. Fisher , Anna E. Garrison , M. Kevin Drost , Goran Jovanovic , Richard Todd Miller , Bruce W. Johnson , Alana Warner-Tuhy , Eric K. Anderson
IPC分类号： B01D61/26 , B01D61/32 , B01D61/28
CPC分类号： A61M1/1686 , A61M1/14 , A61M1/16 , A61M1/1656 , A61M1/1662 , A61M1/1666 , A61M2205/0244 , B01D63/085 , B01D2313/08 , C02F1/02 , C02F1/20 , C02F1/283 , C02F1/44 , C02F1/441 , C02F1/444 , C02F9/005 , C02F2103/026 , C02F2209/03 , C02F2209/05 , C02F2303/04 , F24H1/121 , F24H9/0021 , F28D7/12 , F28D2021/005 , F28F3/08 , F28F2260/02 , Y10T29/494
摘要： A dialysis system includes a filtration system capable of filtering a water stream, a water purification system capable of purifying said water stream in a non-batch process, a mixing system capable of producing a stream of dialysate from mixing one or more dialysate components with the water stream in a non-batch process, and a dialyzer system. The dialyzer may be a microfluidic dialyzer capable of being fluidly coupled to the stream of dialysate and a blood stream.
摘要翻译：透析系统包括能够过滤水流的过滤系统，能够以非分批方法净化所述水流的水净化系统，能够通过将一种或多种透析液组分与非批次过程中的水流，以及透析器系统。透析器可以是能够流体耦合到透析液流和血流的微流体透析器。

8. 发明授权

US08685251B2 Ultra-pasteurization for dialysis machines 有权
标题翻译：超级巴氏消毒用于透析机
公开(公告)号：US08685251B2
公开(公告)日：2014-04-01
申请号：US12960426
申请日：2010-12-03
申请人： Dalibor Jan Smejtek , James R. Curtis
发明人： Dalibor Jan Smejtek , James R. Curtis
IPC分类号： C02F1/44 , B01D61/30 , B01D61/32
CPC分类号： A61M1/1656 , A61M1/14 , A61M1/1662 , A61M1/1664 , A61M2206/11 , B01D63/085 , B01D2313/08 , C02F1/02 , C02F1/20 , C02F1/283 , C02F1/441 , C02F1/444 , C02F9/005 , C02F2103/026 , C02F2209/03 , C02F2209/05 , C02F2303/04 , F28D9/0043 , F28D9/0093 , F28D2021/005 , F28F3/048 , F28F2225/04 , F28F2250/102 , F28F2260/02
摘要： Disclosed herein are water purification and supply systems for medical devices and methods of using. In an embodiment, the system includes a dialysis system including a filtration system capable of filtering a water stream, a water purification system capable of purifying the water stream in a non-batch process, a mixing system capable of producing a stream of dialysate from mixing one or more dialysate components with the water stream in a non-batch process, and a dialyzer system. The dialyzer may be a microfluidic dialyzer capable of being fluidly coupled to the stream of dialysate and a blood stream. The water purification system includes an RO filter 6122, a proportioning valve 6165, a heater 6150, first and second heat exchangers, and a throttle valve 6160.
摘要翻译：本文公开了用于医疗装置的水净化和供应系统和使用方法。在一个实施方案中，该系统包括透析系统，其包括能够过滤水流的过滤系统，能够以非分批方法纯化水流的水净化系统，能够从混合产生透析液流的混合系统一个或多个透析液组分与水流在非分批过程中，以及透析器系统。透析器可以是能够流体耦合到透析液流和血流的微流体透析器。水净化系统包括RO过滤器6122，比例阀6165，加热器6150，第一和第二热交换器以及节流阀6160。

9. 发明申请

US20110189048A1 MODULAR DIALYSIS SYSTEM 审中-公开
标题翻译：模块化透析系统
公开(公告)号：US20110189048A1
公开(公告)日：2011-08-04
申请号：US12960373
申请日：2010-12-03
申请人： James R. Curtis , Michael Baker , Dalibor Jan Smejtek
发明人： James R. Curtis , Michael Baker , Dalibor Jan Smejtek
IPC分类号： B01D61/30 , A61L2/18 , A61L2/24
CPC分类号： A61M1/14 , A61M1/1656 , A61M2209/08
摘要： A dialysis system includes a plurality of modular components. The modular components can be coupled to one another in various configurations, wherein each configuration is optimized for use in a particular environment, such as in a home environment or a travel environment or a dialysis center.
摘要翻译：透析系统包括多个模块化组件。模块化组件可以以各种配置彼此耦合，其中每个配置被优化用于特定环境中，例如在家庭环境或旅行环境或透析中心中。

10. 发明授权

US06966010B1 Application container that allows concurrent execution on multiple Nodes in a Cluster 有权
标题翻译：允许在群集中的多个节点上并发执行的应用程序容器
公开(公告)号：US06966010B1
公开(公告)日：2005-11-15
申请号：US09942911
申请日：2001-08-31
申请人： James R. Curtis , Eric M. Soderberg , James M. Nissen
发明人： James R. Curtis , Eric M. Soderberg , James M. Nissen
IPC分类号： G06F11/00 , G06F11/20
CPC分类号： G06F11/2035 , G06F11/1482
摘要： The present invention provides a process for providing High Availability applications on a Cluster without utilizing a fail-over mechanism. The process utilizes a first instantiation of a Package containing information needed to implement an application on a first Node of a Cluster. Additionally, the process utilizes a second instantiation of the Package on at least one second Node of the Cluster. Upon detection of a fault condition or possible fault condition in an application, a Cluster management system transfers operation of the application from the first Node to the second Node. The second Node utilizing the second instantiation of the Package to immediately implement the application without requiring the Cluster management system to fail-over the application.
摘要翻译：本发明提供了一种用于在群集上提供高可用性应用而不利用故障切换机制的过程。该过程利用包含在集群的第一节点上实现应用所需的信息的包的第一实例化。此外，该过程利用集群的至少一个第二节点上的包的第二实例化。在检测到应用中的故障状况或可能的故障状况时，集群管理系统将应用的操作从第一节点传送到第二节点。第二个节点利用软件包的第二个实例来立即实现应用程序，而不需要集群管理系统故障切换应用程序。

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