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1. 发明申请

WO2008054423A1 MAGNETICALLY CONTROLLABLE ELONGATE DEVICE, SYSTEMS AND METHODS 审中-公开
标题翻译：磁性可控ELELLATE设备，系统和方法
公开(公告)号：WO2008054423A1
公开(公告)日：2008-05-08
申请号：PCT/US2006/060395
申请日：2006-10-31
申请人： UNIVERSITY OF WASHINGTON , MELVILLE, Charles, D.
发明人： MELVILLE, Charles, D.
IPC分类号： A61M25/01
CPC分类号： A61M25/0127 , A61B34/20 , A61B34/70 , A61B34/73 , A61B2034/2051 , A61B2034/732
摘要： The present invention provides improved systems, methods and devices having a flexible elongate body with magnetic elements distributed along a proximal portion to help magnetically control positioning or movement of a proximal portion of the device within a patient's body lumen. A device includes a flexible elongate body having a flexible distal portion and a proximal portion, and one or more magnetic elements distributed along the proximal portion that generate, in response to an applied magnetic field, a force or torque along the proximal portion sufficient to help control positioning or movement of the proximal portion within the patient's body lumen.
摘要翻译：本发明提供了具有柔性细长体的改进的系统，方法和装置，其具有沿着近端部分分布的磁性元件，以帮助磁性地控制装置在患者体腔内的近端部分的定位或移动。一种装置包括具有柔性远侧部分和近端部分的柔性细长主体，以及沿着近端部分分布的一个或多个磁性元件，其响应于所施加的磁场而产生沿近端部分的力或扭矩足以帮助控制近端部分在患者体腔内的定位或运动。

2. 发明申请

WO2013109978A1 DENTAL DEMINERALIZATION DETECTION, METHODS AND SYSTEMS 审中-公开
标题翻译：牙齿脱细胞检测，方法和系统
公开(公告)号：WO2013109978A1
公开(公告)日：2013-07-25
申请号：PCT/US2013/022286
申请日：2013-01-18
申请人： UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION , SEIBEL, Eric, J. , ZHANG, Liang , JOHNSTON, Richard, S. , MELVILLE, Charles, D. , NELSON, Leonard , LEE, Cameron, M. , BERG, Joel
发明人： SEIBEL, Eric, J. , ZHANG, Liang , JOHNSTON, Richard, S. , MELVILLE, Charles, D. , NELSON, Leonard , LEE, Cameron, M. , BERG, Joel
IPC分类号： G01J3/40
CPC分类号： A61B5/0088 , A61B1/00009 , A61B1/00096 , A61B1/00142 , A61B1/015 , A61B1/07 , A61B1/247 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/4547 , A61C19/04 , G01J3/0205 , G01J3/0218 , G01J3/06 , G01J3/10 , G01J3/4406 , G01N21/645 , G01N21/6486 , G01N2021/6421 , G01N2021/6484 , G01N2021/6493
摘要： Methods and systems for detecting early stage dental caries and decays are provided. In particular, in an embodiment, laser-induced autofluorescence (AF) from multiple excitation wavelengths is obtained and analyzed. Endogenous fluorophores residing in the enamel naturally fluoresce when illuminated by wavelengths ranging from ultraviolet into the visible spectrum. The relative intensities of the AF emission changes between different excitation wavelengths when the enamel changes from healthy to demineralized. By taking a ratio of AF emission spectra integrals between different excitation wavelengths, a standard is created wherein changes in AF ratios within a tooth are quantified and serve as indicators of early stage enamel demineralization. The techniques described herein may be used in conjunction with a scanning fiber endoscope (SFE) to provide a reliable, safe and low-cost means for identifying dental caries or decays.
摘要翻译：提供了检测早期龋齿和衰老的方法和系统。特别地，在一个实施例中，获得并分析来自多个激发波长的激光诱导自发荧光（AF）。当从紫外线到可见光谱的波长照射时，驻留在釉质中的内源性荧光团自然发荧光。当釉质从健康变为软化时，AF发射的相对强度在不同的激发波长之间变化。通过采用不同激发波长之间的AF发射光谱积分的比例，创建了一个标准，其中牙齿内AF比的变化被量化并用作早期釉质脱矿质的指标。本文描述的技术可以与扫描光纤内窥镜（SFE）一起使用，以提供用于识别龋齿或衰变的可靠，安全和低成本的方法。

3. 发明公开

EP0928437A1 POSITION DETECTION OF MECHANICAL RESONANT SCANNER MIRROR 失效
标题翻译：机械RESONANZABTASTSPIEGELN体的位置检测
公开(公告)号：EP0928437A1
公开(公告)日：1999-07-14
申请号：EP97943368.0
申请日：1997-09-18
申请人： UNIVERSITY OF WASHINGTON
发明人： MELVILLE, Charles, D.
IPC分类号： G01P15 , G02B7 , G02B26 , G02B27
CPC分类号： G02B26/105 , G01P15/09 , G02B7/1821 , G02B27/017 , Y10S359/90
摘要： Two piezoelectric sensors (78, 80) are mounted on the back of a spring-plate (14) of a mechanical resonance scanner (10) on respective sides of a center line coinciding with an axis of rotation (16). As the scanner mirror (12) rotates back and forth the two sensors are accelerated and decelerated at a 180° phase difference. Each sensor's output voltage crosses a zero level when the acceleration is unchanging. A differential amplifier (88) detects the zero-crossings for motion along the axis of rotation. Common mode rejection eliminates the non-rotational accelerations associated with external vibrations and shocks, and prevents masking the mirror's zero-crossings.

4. 发明申请

WO1996036036A1 VIRTUAL RETINAL DISPLAY WITH FIBER OPTIC POINT SOURCE 审中-公开
标题翻译：具有光纤光源的虚拟终端显示
公开(公告)号：WO1996036036A1
公开(公告)日：1996-11-14
申请号：PCT/US1996005431
申请日：1996-04-19
申请人： UNIVERSITY OF WASHINGTON
发明人： UNIVERSITY OF WASHINGTON , FURNESS, Thomas, A., III , MELVILLE, Charles, D. , TIDWELL, Michael, R.
IPC分类号： G09G03/02
CPC分类号： G02B27/017 , G02B26/10 , G02B27/0172 , G02B2027/0116 , G02B2027/0118 , G02B2027/0132 , G02B2027/0138 , G02B2027/0187 , G02B2027/0198 , G09G3/001 , H04N9/3129
摘要： A virtual retinal display utilizes photon generation and manipulation to create a panoramic, high resolution, color virtual image that is projected directly onto the retina of the eye. The virtual retinal display includes a source of photons, the photons being modulated with video information and scanned by a scanning system in a raster type of pattern directly onto the retina of the user's eye. A single, monofilament optical fiber (300) of very small diameter couples light from the photon generator (308, 314) to the scanning system (16) so as to provide to the scanning system a point source of light at the fiber's exit aperture (306). The photon generator may utilize coherent or non-coherent light. Further, the photon generator may utilize color light emitters so as to scan a colored virtual image directly onto the retina of the user's eye.
摘要翻译：虚拟视网膜显示器利用光子产生和操纵来创建直接投影到眼睛的视网膜上的全景，高分辨率的彩色虚像。虚拟视网膜显示器包括光子源，光子被视频信息调制，并以光栅类型的扫描系统直接扫描到用户的眼睛的视网膜上。非常小直径的单个单丝光纤（300）将来自光子发生器（308,314）的光耦合到扫描系统（16），以向扫描系统提供光纤出射孔处的点光源（ 306）。光子发生器可以利用相干或非相干光。此外，光子发生器可以利用彩色发光器，以将有色虚拟图像直接扫描到用户的眼睛的视网膜上。

5. 发明申请

WO1996013746A1 MINIATURE OPTICAL SCANNER FOR A TWO AXIS SCANNING SYSTEM 审中-公开
标题翻译：用于双轴扫描系统的微型光学扫描仪
公开(公告)号：WO1996013746A1
公开(公告)日：1996-05-09
申请号：PCT/US1995012599
申请日：1995-10-02
申请人： BOARD OF REGENTS OF THE UNIVERSITY OF WASHINGTON
发明人： BOARD OF REGENTS OF THE UNIVERSITY OF WASHINGTON , MELVILLE, Charles, D. , FURNESS, Thomas, A., III , TIDWELL, Michael, R. , KOLLIN, Joel, S. , JOHNSTON, Richard, S.
IPC分类号： G02B26/08
CPC分类号： G02B26/10 , G02B7/1821 , G02B26/101
摘要： A miniature optical scanner (10) includes an electromagnetic drive having stationary magnets (26, 28) and stationary drive coils (22, 24) to minimize the rotational inertia of the scanner and increase the scanner's resonant frequency. The scanner is such that the resonant frequency is manually tunable as well as automatically adjustable to compensate for variables causing frequency drift. The optical scan angle is increased by employing a multiplying mirror with the optical scanner (10). For a two axis scanning system, the multiplying mirror may be formed of a second optical scanner to increase the optical scan angle relative to both of the axes.
摘要翻译：微型光学扫描器（10）包括具有固定磁体（26,28）和静止驱动线圈（22,24）的电磁驱动器，以最小化扫描仪的旋转惯性并增加扫描器的谐振频率。扫描器使得谐振频率可手动调节，并且可自动调整，以补偿导致频率漂移的变量。通过使用乘法镜与光学扫描器（10）来增加光学扫描角度。对于双轴扫描系统，乘法反射镜可以由第二光学扫描器形成，以增加相对于两个轴的光学扫描角度。

6. 发明申请

WO2006104489A1 METHODS AND SYSTEMS FOR CREATING SEQUENTIAL COLOR IMAGES 审中-公开
标题翻译：创建顺序色彩图像的方法和系统
公开(公告)号：WO2006104489A1
公开(公告)日：2006-10-05
申请号：PCT/US2005/010734
申请日：2005-03-29
申请人： UNIVERSITY OF WASHINGTON , JOHNSTON, Richard, S. , LEE, Cameron, M. , MELVILLE, Charles, D.
发明人： JOHNSTON, Richard, S. , LEE, Cameron, M. , MELVILLE, Charles, D.
IPC分类号： H04N7/18 , H04N9/47 , H01L27/00 , H01J3/14 , A61B6/00
CPC分类号： H04N3/08
摘要： The present invention provides methods, software, and systems (fig 9) that allow a scanning beam device (fig 9, item 14) to create full or partial color images (fig 9, item 30) using sequential color methods (fig 9, item 30). The methods of the present invention may use sequential color concepts to improve image generation (fig 9, item 34) without increasing scan rates while using light source modulation rates (fig 9, item 38) that are much less than conventional methods.
摘要翻译：本发明提供了允许扫描光束装置（图9，项目14）使用顺序彩色方法创建全部或部分彩色图像（图9，项目30）的方法，软件和系统（图9）（图9，项目 30）。本发明的方法可以使用顺序颜色概念来改善图像生成（图9，项目34），而不增加扫描速率同时使用比常规方法更少的光源调制速率（图9，项目38）。

7. 发明申请

WO1998013719A1 POSITION DETECTION OF MECHANICAL RESONANT SCANNER MIRROR 审中-公开
标题翻译：机械共振扫描仪的位置检测
公开(公告)号：WO1998013719A1
公开(公告)日：1998-04-02
申请号：PCT/US1997016588
申请日：1997-09-18
申请人： UNIVERSITY OF WASHINGTON
发明人： UNIVERSITY OF WASHINGTON , MELVILLE, Charles, D.
IPC分类号： G02B26/08
CPC分类号： G02B26/105 , G01P15/09 , G02B7/1821 , G02B27/017 , Y10S359/90
摘要： Two piezoelectric sensors (78, 80) are mounted on the back of a spring-plate (14) of a mechanical resonance scanner (10) on respective sides of a center line coinciding with an axis of rotation (16). As the scanner mirror (12) rotates back and forth the two sensors are accelerated and decelerated at a 180 DEG phase difference. Each sensor's output voltage crosses a zero level when the acceleration is unchanging. A differential amplifier (88) detects the zero-crossings for motion along the axis of rotation. Common mode rejection eliminates the non-rotational accelerations associated with external vibrations and shocks, and prevents masking the mirror's zero-crossings.
摘要翻译：两个压电传感器（78,80）安装在与旋转轴线（16）重合的中心线的相应侧上的机械共振扫描器（10）的弹簧板（14）的后部。当扫描器反射镜（12）来回旋转时，两个传感器以180°的相位差被加速和减速。当加速度不变时，每个传感器的输出电压都会超过零电平。差分放大器（88）检测沿着旋转轴线的运动的过零点。共模抑制消除了与外部振动和冲击相关的非旋转加速度，并防止遮蔽镜的过零点。

8. 发明申请

WO1997037339A1 VIRTUAL RETINAL DISPLAY WITH EXPANDED EXIT PUPIL 审中-公开
标题翻译：虚拟终极显示与扩展退出PUPIL
公开(公告)号：WO1997037339A1
公开(公告)日：1997-10-09
申请号：PCT/US1997003302
申请日：1997-02-27
申请人： UNIVERSITY OF WASHINGTON
发明人： UNIVERSITY OF WASHINGTON , KOLLIN, Joel, S. , JOHNSTON, Richard, S. , MELVILLE, Charles, D.
IPC分类号： G09G05/00
CPC分类号： G02B26/101 , G02B27/0081 , G02B27/017 , G02B27/0172
摘要： A display device (10) is achieved using an optical system which generates an expanded exit pupil (21) without compromising magnification or resolution. Modulated light from a source (12) is converged toward a focal point by an optics subsystem (14). A scanning subsystem (16) deflects the converging light, and thus the focal point, along a raster pattern to define a curved intermediate image plane (15). An exit pupil expanding apparatus (18) defines a curved surface which coincides with the curved image plane (15). Impinging light rays at a given instant in time span a given incidence angle ( theta i). Exiting light rays span a larger angle ( theta o). The exiting light spans a larger surface area of an ensuing eyepiece (20). In turn an expanded exit pupil (21) occurs beyond the eyepiece. Exit pupil expanding embodiments include a curved diffractive optical element (300), fiber optic face plate (320), lens array (340) and diffuser (360). The diffractive optical element generates multiple exit pupils (304-316), while the other embodiments generate enlarged exit pupils.
摘要翻译：使用在不损害放大率或分辨率的情况下产生扩展出射光瞳（21）的光学系统实现显示装置（10）。来自光源（12）的调制光通过光学子系统（14）会聚到焦点。扫描子系统（16）沿着光栅图案偏转会聚光，从而偏转焦点，以限定弯曲的中间像平面（15）。出射光瞳扩张装置（18）限定与曲面像平面（15）重合的曲面。在给定的瞬间，在给定的入射角（θi）中引发光线。退出光线跨越较大的角度（θo）。出射光横跨随后的目镜（20）的较大表面积。反过来，扩展的出射光瞳（21）发生在目镜之外。退出光瞳扩展实施例包括弯曲衍射光学元件（300），光纤面板（320），透镜阵列（340）和漫射器（360）。衍射光学元件产生多个出射光瞳（304-316），而其他实施例产生放大的出射光瞳。

9. 发明公开

EP1129383A1 METHOD AND APPARATUS FOR DETERMINING OPTICAL DISTANCE 审中-公开
标题翻译：方法和设备，用来确定光学距离
公开(公告)号：EP1129383A1
公开(公告)日：2001-09-05
申请号：EP99961558.6
申请日：1999-11-02
申请人： THE UNIVERSITY OF WASHINGTON
发明人： MELVILLE, Charles, D. , TIDWELL, Michael , JOHNSTON, Richard, S. , KOLLIN, Joel, S.
IPC分类号： G02B27/14 , G09G5/00
CPC分类号： G01S11/12 , G01C3/08 , G02B7/28 , H04N13/236
摘要： Apparent distance of a pixel within an optical field of view is determined. Incoming light is scanned along a raster pattern to direct light for a select pixel onto a light distance detector. The distance is sampled for each pixel or for a group of pixels. The light distance detector includes a concentric set of rings sensors. The larger the spot of light corresponding to the pixel, the more rings are impinged. The diameter of the spot is proportional to the distance at which the light originated (e.g., light source or object from which light was reflected). Alternatively, a variable focus lens (VFL) adjusts focal length for a given pixel to achieve a standard spot size. The distance at which the light originated correlates to the focal length of the VFL.

10. 发明公开

EP1053499A1 VIRTUAL RETINAL DISPLAY WITH EYE TRACKING 审中-公开
标题翻译：眼动跟踪虚拟视网膜显示屏
公开(公告)号：EP1053499A1
公开(公告)日：2000-11-22
申请号：EP99901453.3
申请日：1999-01-13
申请人： University of Washington
发明人： MELVILLE, Charles, D. , JOHNSTON, Richard, S.
IPC分类号： G02B27/14
CPC分类号： G06K9/00604 , A61B5/117 , A61B5/1171 , G02B7/287 , G02B27/0093 , G02B27/017 , G02B27/0172 , G02B2027/0187 , G09G3/001
摘要： Light emitted from a virtual retinal display light source passes through a beamsplitter to a scanning subsystem and on to an eyepiece and the viewer's eye. Some of the light is reflected from the viewer's eye passing back along the same path. Such light however is deflected at the beamsplitter toward a photodetector. The reflected light is detected and correlated to the display scanner's position. The content of the reflected light and the scanner position for such sample is used to generate a map of the viewer's retina. Such map includes 'landmarks' such as the viewer's optic nerve, fovea, and blood vessels. The map of the viewer's retina is stored and used for purposes of viewer identification. The viewer's fovea position is monitored to track where the viewer is looking

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