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1. 发明授权

US10670566B2 Rapid antimicrobial susceptibility testing using piezoelectric sensor 审中-公开
公开(公告)号：US10670566B2
公开(公告)日：2020-06-02
申请号：US15777750
申请日：2016-11-18
申请人： Wan Y. Shih , Wei-Heng Shih , Christopher Emery , Xin Xu , Suresh Joshi , Wei Wu
发明人： Wan Y. Shih , Wei-Heng Shih , Christopher Emery , Xin Xu , Suresh Joshi , Wei Wu
IPC分类号： C12Q1/18 , G01N29/12 , G01N29/036 , G01N29/02
摘要： A system for and method of antimicrobial susceptibility testing includes detecting a resonance peak of a sensor provided with live microbes on a surface thereof; applying a substance to the live microbes; detecting a resonance peak of said sensor after application of said substance; determining a width of a top of each of said resonance peaks before and after application of the substance from one of: (1) a phase angle versus frequency plot where the phase angle is the phase angle of the electrical impedance of said sensor. (2) a real part of a plot of an electrical impedance versus frequency of said sensor. (3) a plot of a magnitude of electrical impedance versus frequency of said sensor, and (4) a phase angle versus frequency plot where the phase angle is the phase angle between an output voltage and an input voltage of said sensor, and comparing the determined widths of tops of said resonance peaks or standard deviations of the frequency of said resonance peaks to determine antimicrobial susceptibility including the minimum inhibitory concentration (MIC).

2. 发明申请

US20160356769A1 Piezoelectric Plate Sensor and Uses Thereof 审中-公开
标题翻译：压电板传感器及其用途
公开(公告)号：US20160356769A1
公开(公告)日：2016-12-08
申请号：US15101788
申请日：2014-12-19
申请人： Wan Y. Shih , Wei Wu , Wei-Heng Shih , Mehmet Cagri Soylu , Haitao Guo , Suresh G. Joshi , Ceyhun Ekrim Kirimli , Ying-Hsiu Su
发明人： Wan Y. Shih , Wei Wu , Wei-Heng Shih , Mehmet Cagri Soylu , Haitao Guo , Suresh G. Joshi , Ceyhun Ekrim Kirimli , Ying-Hsiu Su
IPC分类号： G01N33/543 , G01N29/036 , G01N29/02 , C12Q1/68
CPC分类号： G01N33/54373 , C12Q1/6825 , G01N29/022 , G01N29/036 , G01N33/54393 , G01N2291/0255 , G01N2291/0256 , G01N2291/0427 , C12Q2565/607
摘要： A piezoelectric plate sensor comprising a piezoelectric layer; two electrodes; and an insulation layer. The insulation layer is produced by soaking the piezoelectric layer and two electrodes in a mercaptopropyltrimethoxysilane solution with an amount of water from 0.1 v/v. % to about 1 v/v % and at pH from about 8 to about 150 for a period from about 8 to about 15 hours, and the mercaptopropyltrimethoxysilane solution has a concentration of mercaptopropyltrimethoxysilane from about 0.01 v/v % to about 0.5 v/v %. A method of detecting a biomolecule in a sample using the piezoelectric plate sensor in particular, that of detecting a genetic marker with PCR sensitivity and specificity without the need of DNA isolation or amplification is also provided. The piezoelectric plate sensor may be used to diagnose various diseases including breast cancer, myocardial infarction, diarrhea, Clostridium difficile infection, and hepatitis B infection.
摘要翻译：一种压电板传感器，包括压电层; 两个电极和绝缘层。通过将压电层和两个电极浸入0.1V / V的水中的巯基丙基三甲氧基硅烷溶液中来制备绝缘层。％至约1v / v％和约8至约150的pH约8至约15小时，巯基丙基三甲氧基硅烷溶液具有约0.01v / v％至约0.5v / v的巯基丙基三甲氧基硅烷浓度％。还提供了使用压电板传感器检测样品中生物分子的方法，特别是在不需要DNA分离或扩增的情况下用PCR灵敏度和特异性检测遗传标记物的方法。压电板传感器可用于诊断包括乳腺癌，心肌梗死，腹泻，艰难梭菌感染和乙型肝炎感染在内的各种疾病。

3. 发明申请

US20190120833A1 Piezoelectric Plate Sensor and Uses Thereof 审中-公开
公开(公告)号：US20190120833A1
公开(公告)日：2019-04-25
申请号：US16216848
申请日：2018-12-11
申请人： Wan Y. Shih , Wei Wu , Wei-Heng Shih , Mehmet Cagri Soylu , Haitao Guo , Suresh G. Joshi , Ceyhun Ekrim Kirimli , Ying-Hsiu Su
发明人： Wan Y. Shih , Wei Wu , Wei-Heng Shih , Mehmet Cagri Soylu , Haitao Guo , Suresh G. Joshi , Ceyhun Ekrim Kirimli , Ying-Hsiu Su
IPC分类号： G01N33/543 , G01N29/02 , G01N29/036 , C12Q1/6825
摘要： A piezoelectric plate sensor comprising a piezoelectric layer; two electrodes; and an insulation layer. The insulation layer is produced by soaking the piezoelectric layer and two electrodes in a mercaptopropyltrimethoxysilane solution with an amount of water from 0.1 v/v. % to about 1 v/v % and at pH from about 8 to about 150 for a period from about 8 to about 15 hours, and the mercaptopropyltrimethoxysilane solution has a concentration of mercaptopropyltrimethoxysilane from about 0.01 v/v % to about 0.5 v/v %. A method of detecting a biomolecule in a sample using the piezoelectric plate sensor in particular, that of detecting a genetic marker with PCR sensitivity and specificity without the need of DNA isolation or amplification is also provided. The piezoelectric plate sensor may be used to diagnose various diseases including breast cancer, myocardial infarction, diarrhea, Clostridium difficile infection, and hepatitis B infection.

4. 发明申请

US20220128551A1 Piezoelectric Plate Sensor and Uses Thereof 有权
公开(公告)号：US20220128551A1
公开(公告)日：2022-04-28
申请号：US17567992
申请日：2022-01-04
申请人： Wan Y. Shih , Wei Wu , Wei-Heng Shih , Mehmet Cagri Soylu , Haitao Guo , Suresh G. Joshi , Ceyhun Ekrim Kirimli , Ying-Hsiu Su
发明人： Wan Y. Shih , Wei Wu , Wei-Heng Shih , Mehmet Cagri Soylu , Haitao Guo , Suresh G. Joshi , Ceyhun Ekrim Kirimli , Ying-Hsiu Su
IPC分类号： G01N33/543 , G01N29/02 , G01N29/036 , C12Q1/6825
摘要： A piezoelectric plate sensor comprising a piezoelectric layer; two electrodes; and an insulation layer. The insulation layer is produced by soaking the piezoelectric layer and two electrodes in a mercaptopropyltrimethoxysilane solution with an amount of water from 0.1 v/v. % to about 1 v/v % and at pH from about 8 to about 150 for a period from about 8 to about 15 hours, and the mercaptopropyltrimethoxysilane solution has a concentration of mercaptopropyltrimethoxysilane from about 0.01 v/v % to about 0.5 v/v %. A method of detecting a biomolecule in a sample using the piezoelectric plate sensor in particular, that of detecting a genetic marker with PCR sensitivity and specificity without the need of DNA isolation or amplification is also provided. The piezoelectric plate sensor may be used to diagnose various diseases including breast cancer, myocardial infarction, diarrhea, Clostridium difficile infection, and hepatitis B infection.

5. 发明授权

US10197565B2 Piezoelectric plate sensor and uses thereof 有权
公开(公告)号：US10197565B2
公开(公告)日：2019-02-05
申请号：US15101788
申请日：2014-12-19
申请人： Wan Y. Shih , Wei Wu , Wei-Heng Shih , Mehmet Cagri Soylu , Haitao Guo , Suresh G. Joshi , Ceyhun Ekrim Kirimli , Ying-Hsiu Su
发明人： Wan Y. Shih , Wei Wu , Wei-Heng Shih , Mehmet Cagri Soylu , Haitao Guo , Suresh G. Joshi , Ceyhun Ekrim Kirimli , Ying-Hsiu Su
IPC分类号： G01N33/543 , G01N29/02 , G01N29/036 , C12Q1/6825
摘要： A piezoelectric plate sensor comprising a piezoelectric layer; two electrodes; and an insulation layer. The insulation layer is produced by soaking the piezoelectric layer and two electrodes in a mercaptopropyltrimethoxysilane solution with an amount of water from 0.1 v/v. % to about 1 v/v % and at pH from about 8 to about 150 for a period from about 8 to about 15 hours, and the mercaptopropyltrimethoxysilane solution has a concentration of mercaptopropyltrimethoxysilane from about 0.01 v/v % to about 0.5 v/v %. A method of detecting a biomolecule in a sample using the piezoelectric plate sensor in particular, that of detecting a genetic marker with PCR sensitivity and specificity without the need of DNA isolation or amplification is also provided. The piezoelectric plate sensor may be used to diagnose various diseases including breast cancer, myocardial infarction, diarrhea, Clostridium difficile infection, and hepatitis B infection.

6. 发明授权

US09987192B2 Massaging devices 有权
公开(公告)号：US09987192B2
公开(公告)日：2018-06-05
申请号：US14603786
申请日：2015-01-23
申请人： Wei Wu
发明人： Wei Wu
IPC分类号： A61H19/00 , A61H23/02
CPC分类号： A61H23/0263 , A61H19/44 , A61H2201/0153 , A61H2201/1253 , A61H2201/5025
摘要： A massaging device is provided. The massaging device includes a shell having first end and a second end, the first end being a massaging head, a size and a shape of the shell configured to massage a body part of a user. The massaging device also includes an opening disposed close to the second end. The massaging device further includes a housing to house a vibrating motor, the housing configured to be inserted into the shell through the opening. The massaging device also includes a rolling member disposed at the opening, and the rolling member is configured to control the vibration of the vibrating motor when being operated by a user.

7. 发明授权

US09638625B2 Apparatus for filtering species 有权
公开(公告)号：US09638625B2
公开(公告)日：2017-05-02
申请号：US14345277
申请日：2011-10-27
申请人： Ansoon Kim , Zhiyong Li , Wei Wu
发明人： Ansoon Kim , Zhiyong Li , Wei Wu
IPC分类号： G01J3/44 , G01N21/05 , G01N21/65 , G01N21/552 , G01N33/49 , G01N1/40 , B82Y20/00
CPC分类号： G01N21/05 , B82Y20/00 , G01N21/554 , G01N21/658 , G01N33/491 , G01N2001/4088 , G01N2021/651
摘要： An apparatus for filtering species in a fluid includes a body having a first side and a second side, a first set of nano-fingers positioned on the body near the first side, a second set of nano-fingers positioned on the body closer to the second side than the first set of nano-fingers, wherein the nano-fingers in the second set of nano-fingers are arranged on the body at a relatively more densely than the nano-fingers in the first set of nano-fingers, and a cover positioned over the first set of nano-fingers and the second set of nano-fingers to form a channel with the body within which the first and second sets of nano-fingers are positioned.

8. 发明授权

US09441231B2 Chimeric and proline rich protein promoters for expression in plants 有权
标题翻译：用于在植物中表达的嵌合和富含脯氨酸的蛋白启动子
公开(公告)号：US09441231B2
公开(公告)日：2016-09-13
申请号：US12329303
申请日：2008-12-05
申请人： Stanislaw Flasinski , Shirley Xiaoli Guo , Wei Wu
发明人： Stanislaw Flasinski , Shirley Xiaoli Guo , Wei Wu
IPC分类号： C12N15/82
CPC分类号： C12N15/8216 , C12N7/00 , C12N15/8227 , C12N15/8245 , C12N15/8247 , C12N15/8249 , C12N15/8251 , C12N15/8257 , C12N15/8261 , C12N15/8271 , C12N15/8273 , C12N15/8274 , C12N15/8279 , C12N15/8281 , C12N15/8282 , C12N15/8283 , C12N15/8285 , C12N15/8286 , C12N2730/00043
摘要： The present invention provides regulatory polynucleotide molecules isolated from plant proline rich protein genes and linked to a viral enhancer molecule. The invention further discloses compositions, polynucleotide constructs, transformed host cells, transgenic plants and seeds containing the regulatory polynucleotide sequences, and methods for preparing and using the same.
摘要翻译：本发明提供从植物富含脯氨酸的蛋白质基因分离并连接到病毒增强子分子的调节性多核苷酸分子。本发明进一步公开了组合物，多核苷酸构建体，转化的宿主细胞，含有调控多核苷酸序列的转基因植物和种子，以及制备和使用其的方法。

9. 发明授权

US09231786B2 On the managed peer-to-peer sharing in cellular networks 有权
标题翻译：在蜂窝网络中的受管点对点共享
公开(公告)号：US09231786B2
公开(公告)日：2016-01-05
申请号：US13400755
申请日：2012-02-21
申请人： Wei Wu , Khiem Le , Noun Choi
发明人： Wei Wu , Khiem Le , Noun Choi
IPC分类号： G06F15/16 , H04L12/66 , H04L29/08
CPC分类号： H04L67/1061 , H04L12/66 , H04L67/104 , H04L67/1063 , H04L67/1072 , H04W60/00
摘要： A method, system and apparatus are provided for performing peer-to-peer (P2P) data sharing operations between user equipment (UE) devices in a wireless-enabled communications environment. A first client node comprises content data and operates in a server peer mode to provide content data. A second client node submits a request to a P2P application server (P2P AS) for the content data. In response, the P2P AS provides the address of the first client node to the second client node. The second client node then uses the provided address to submit a request to the first client node to provide the content data. The first client node accepts the request and then provides the content data to the second client node.
摘要翻译：提供了一种用于在启用无线的通信环境中在用户设备（UE）设备之间执行对等（P2P）数据共享操作的方法，系统和装置。第一客户端节点包括内容数据并以服务器对等模式操作以提供内容数据。第二客户节点向P2P应用服务器（P2P AS）提交内容数据的请求。作为响应，P2P AS向第二客户端节点提供第一客户机节点的地址。然后，第二客户端节点使用提供的地址向第一客户机节点提交请求以提供内容数据。第一个客户机节点接受请求，然后将内容数据提供给第二个客户机节点。

10. 发明申请

US20150196876A1 METHOD OF PREPARING AN STT-TYPE ZEOLITE FOR USE AS A CATALYST IN SELECTIVE CATALYTIC REDUCTION REACTIONS 审中-公开
标题翻译：制备用于选择性催化还原反应中催化剂的STT型沸石的方法
公开(公告)号：US20150196876A1
公开(公告)日：2015-07-16
申请号：US14669197
申请日：2015-03-26
申请人： Manjola Mancka , Yunkui Li , Jeffery LaChapelle , Wei Wu
发明人： Manjola Mancka , Yunkui Li , Jeffery LaChapelle , Wei Wu
IPC分类号： B01D53/94 , B01J29/70 , B01J29/76 , B01J37/08 , B01J29/06 , C01B39/48 , B01J37/30
CPC分类号： B01D53/9418 , B01D53/9431 , B01D2255/50 , B01J29/061 , B01J29/70 , B01J29/7049 , B01J29/72 , B01J29/76 , B01J35/002 , B01J37/08 , B01J37/30 , B01J2229/16 , B01J2229/183 , B01J2229/186 , B01J2229/37 , B01J2229/40 , C01B37/02 , C01B39/026 , C01B39/48
摘要： A method of preparing a crystalline STT-type zeolite that has a mole ratio greater than about 15:1 of a tetravalent element oxide to a trivalent element oxide is disclosed along with a gas treatment system that incorporates the STT-type zeolite and a process for treating a gas using the STT-type zeolite. The method generally comprises forming an aqueous mixture comprising a tetravalent element oxide source, a trivalent element oxide source, a source of alkali metal, and an organic structure directing agent; maintaining the mixture under conditions that crystallize crystals of a STT-type zeolite; and recovering the crystals The STT-type zeolite crystals exhibit x-ray diffraction 2-theta degree peaks at: 8.26, 8.58, 9.28, 9.54, 10.58, 14.52, 15.60, 16.43, 17.13, 17.74, 18.08, 18.46, 19.01, 19.70, 20.12, 20.38, 20.68, 21.10, 21.56, 22.20, 22.50, 22.78, 23.36, 23.76, 23.99, 24.54, 24.92, 25.16, 25.58, 25.80, 26.12, 26.94, 27.38, 27.92, 28.30, 28.60, 29.24, 29.48, 30.08, 30.64, 31.20, 31.46, 31.80, 32.02, 32.60, 33.60, and 34.43.
摘要翻译：公开了一种将四价元素氧化物与三价元素氧化物的摩尔比大于约15:1的结晶STT型沸石与含有STT型沸石的气体处理系统一起制备，使用STT型沸石处理气体。该方法通常包括形成包含四价元素氧化物源，三价元素氧化物源，碱金属源和有机结构导向剂的含水混合物; 在使STT型沸石的晶体结晶的条件下保持混合物; 并回收晶体STT型沸石晶体在8.26,8.58,9.28,9.54,10.58,14.52,15.60,16.43,17.13,17.74,18.08,18.46,19.01,19.70℃下显示x射线衍射2θ度峰， 20.12，20.38，20.68，21.10，21.56，22.20，22.50，22.78，23.36，23.76，23.99，24.54，24.92，25.16，25.58，25.80，26.12，26.94，27.38,27.92,28.30,28.60,29.24,29.48,30.08， 30.64，31.20，31.46，31.80，32.02，32.60，33.60，和34.43。

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