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1. 发明授权

US06721238B2 Magneto-optical recording medium having multiple magnetic layers capable of reducing reproducing laser power 失效
标题翻译：具有能够减少再现激光功率的多个磁性层的磁光记录介质
公开(公告)号：US06721238B2
公开(公告)日：2004-04-13
申请号：US09996418
申请日：2001-11-29
申请人： Yasuhito Tanaka , Yoshihiro Muto
发明人： Yasuhito Tanaka , Yoshihiro Muto
IPC分类号： G11B1100
CPC分类号： G11B11/10586 , G11B11/10584 , Y10T428/1121
摘要： A magneto-optical recording medium for recording and reproducing carriers by laser beam irradiation includes a first magnetic layer which is magnetized in the in-plane direction at room temperature and is perpendicularly magnetized at a predetermined temperature T1 or more; a second magnetic layer which is in contact with the first magnetic layer, has a Curie temperature Tc2 higher than the predetermined temperature T1, and has in-plane magnetic anisotropy up to the Curie temperature Tc2; a third magnetic layer which has a Curie temperature Tc3 higher than the predetermined temperature T1 and has perpendicular magnetic anisotropy at least in a predetermined range of a temperature distribution of the magneto-optical recording medium during laser beam irradiation when reproducing; and a rare earth metal layer formed between the third magnetic layer and the second magnetic layer.
摘要翻译：用于通过激光束照射来记录和再现载体的磁光记录介质包括在室温下在面内方向被磁化并在预定温度T1或更高的温度下垂直磁化的第一磁性层; 与第一磁性层接触的第二磁性层具有高于预定温度T1的居里温度Tc2，具有高达居里温度Tc2的面内磁各向异性; 具有比预定温度T1高的居里温度Tc3的第三磁性层，并且在再现时在激光束照射期间至少在磁光记录介质的温度分布的预定范围内具有垂直的磁各向异性; 以及形成在第三磁性层和第二磁性层之间的稀土金属层。

2. 发明申请

US20140302082A1 NUCLEIC ACID CONSTRUCT COMPRISING NUCLEIC ACID DERIVED FROM GENOME OF HEPATITIS C VIRUS OF GENOTYPE 1B, HEPATITIS C VIRUS GENOME-REPLICATING CELLS TRANSFECTED WITH THE SAME, AND METHOD FOR PRODUCING INFECTIOUS HEPATITIS C VIRUS PARTICLES 有权
标题翻译：含有基因组1B的乙型肝炎病毒C型病毒基因组的核酸构建体，与其转染的丙型肝炎病毒基因组代谢细胞及其生产感染性丙型肝炎病毒颗粒的方法
公开(公告)号：US20140302082A1
公开(公告)日：2014-10-09
申请号：US14009049
申请日：2012-03-30
申请人： Takaji Wakita , Tomoko Date , Yasuhito Tanaka , Masashi Mizokami
发明人： Takaji Wakita , Tomoko Date , Yasuhito Tanaka , Masashi Mizokami
IPC分类号： C12N7/00 , C12Q1/70 , C07K16/08
CPC分类号： C12N7/00 , A61K39/00 , A61K39/12 , C07K14/005 , C07K16/082 , C07K16/109 , C12N15/86 , C12N2770/24221 , C12N2770/24222 , C12N2770/24231 , C12N2770/24234 , C12N2770/24243 , C12N2770/24251 , C12Q1/707 , C12Q2600/136 , C12Q2600/156
摘要： A subgenomic replicon RNA (nucleic acid) having an excellent autonomously replicating ability and a fullgenomic replicon RNA (nucleic acid) having an excellent autonomously replicating ability and infectious HCV particle-producing ability, each derived from a novel HCV of genotype 1b, are provided. Particularly, a subgenomic replicon RNA (nucleic acid) and a fullgenomic replicon RNA (nucleic acid), each derived from an HCV genome of the NC1 strain which is a novel HCV genotype 1b isolated from a patient with acute severe hepatitis C, are provided.
摘要翻译：提供了具有优异的自主复制能力的亚基因组复制子RNA（核酸）和具有优异的自主复制能力和感染性HCV颗粒产生能力的全基因组复制子RNA（核酸），各自源自基因型1b的新型HCV。特别地，提供了从NC1菌株的HCV基因组衍生的亚基因组复制子RNA（核酸）和全基因组复制子RNA（核酸），其是从急性重症丙型肝炎患者分离的新型HCV基因型1b。

3. 发明申请

US20110160252A1 PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OR PREVENTION OF HBV INFECTION 审中-公开
标题翻译：用于治疗或预防HBV感染的药物组合物
公开(公告)号：US20110160252A1
公开(公告)日：2011-06-30
申请号：US12999055
申请日：2009-06-18
申请人： Masashi Mizokami , Yasuhito Tanaka , Masaya Sugiyama , Masayuki Sudoh
发明人： Masashi Mizokami , Yasuhito Tanaka , Masaya Sugiyama , Masayuki Sudoh
IPC分类号： A61K31/44 , C07C229/34 , A61K31/195 , C07D213/55 , A61P31/12
CPC分类号： A61K31/13 , A61K31/165 , A61K31/201 , A61K31/381 , A61K31/405 , A61K31/4406 , A61K31/4418
摘要： First, the present inventors assessed the effect of the compound represented by formula (III) below on Huh-7 cells infected with HBV, and demonstrated that the compound alone had an anti-HBV effect in vitro.Formula (III) Then, the present inventors revealed that the HBV replication-suppressing effect of PEG-IFN is enhanced in chimeric mice having a human liver infected with genotype C or A HBV when PEG-IFN is used in combination with the compound represented by formula (III) above. The present inventors also revealed that the HBV replication-suppressing effect of Entecavir is enhanced in chimeric mice having a human liver infected with genotype C HBV (wild-type and Entecavir-resistant strains) when Entecavir is used in combination with the compound represented by formula (III) above. In addition, the present inventors revealed that the compound represented by formula (III) above exerts the anti-HBV effect not only against wild-type HBV strains but also against Entecavir- and/or Lamivudine-resistant HBV strains.
摘要翻译：首先，本发明人评估了下述式（III）表示的化合物对HBV感染的Huh-7细胞的作用，并证明该化合物在体外具有抗HBV作用。式（III）然后，本发明人揭示了当将PEG-IFN与由下列化合物组合使用时，将具有基因型C或A HBV感染的人肝的嵌合小鼠中的PEG-IFN的HBV复制抑制作用增强上述式（III）。本发明人还发现，当恩替卡韦与式（I）表示的化合物组合使用时，恩替卡韦的HBV复制抑制作用在具有感染基因型C HBV（野生型和恩替卡韦抗性菌株）的人肝脏的嵌合小鼠中得到增强（三）。此外，本发明人发现，上述式（III）表示的化合物不仅对抗野生型HBV株而且对依替卡韦和/或拉米夫定耐药的HBV株产生抗HBV作用。

4. 发明申请

US20110126791A1 EXHAUST POPPET VALVE AND SOLUTION HEAT TREATMENT METHOD OF THE SAME 有权
标题翻译：排气阀和溶液热处理方法
公开(公告)号：US20110126791A1
公开(公告)日：2011-06-02
申请号：US13055222
申请日：2008-07-25
申请人： Yasuhito Tanaka , Hisanaga Yokoyama
发明人： Yasuhito Tanaka , Hisanaga Yokoyama
IPC分类号： F01L3/02 , C21D9/00 , C21D1/00 , C21D6/00 , C22F1/10
CPC分类号： C22C38/02 , B21K1/22 , C21D1/10 , C21D1/42 , C21D6/00 , C21D9/00 , C21D2211/001 , C21D2221/00 , F01L1/0532 , F01L1/143 , F01L3/00 , F01L3/02 , F01L3/08 , F01L3/20 , F01L2101/00 , F01L2103/00 , F01L2820/01 , Y02P10/253
摘要： Object of the Invention The invention provides a forged exhaust poppet valve and a method of solution heat treating the same, in which only a predetermined portion of the valve is subjected to the solution heat treatment so as to provide the seat portion of the valve with satisfactory wear resistance, and a predetermined transitional neck-stem region with satisfactory high-temperature creep strength.Means for Achieving the Object An exhaust poppet valve (10) comprises a head portion (12) which has a seat portion (14) on the outer periphery thereof and is integral with the diametrically tapered neck portion (16) of a stem portion (18) of the valve. Using a radio-frequency heating apparatus, a solution heat treatment is given to a predetermined transitional region (A) defined between the neck and stem portions that is exposed to exhaust air during a valve opening period so that the grain size in the region (A) is controlled not to exceed ASTM 10. Thus, not only required high-temperature creep strength is secured in the transitional neck-shaft region (A) but also necessary hardness (wear resistance) is secured in the seat portion (14) of the valve (10), thereby rendering the exhaust poppet valve highly durable.
摘要翻译：发明目的本发明提供了一种锻造排气提升阀及其热处理方法，其中仅对阀的预定部分进行固溶热处理，以使阀的座部分具有令人满意的耐磨性以及具有令人满意的高温蠕变强度的预定的过渡颈部区域。用于实现对象的装置排气提升阀（10）包括头部（12），头部（12）在其外周上具有座部（14），并与杆部（18）的直径锥形颈部（16）成一体）。使用射频加热装置，在限定在颈部和茎部之间的预定过渡区域（A）进行固溶热处理，其在阀打开期间暴露于排气中，使得区域（A ）被控制为不超过ASTM 10.因此，不仅在过渡颈部轴区域（A）中确保了所需的高温蠕变强度，而且确保了必要的硬度（耐磨性）在座椅部分（14）中阀（10），从而使排气提升阀高度耐用。

5. 发明授权

US07100754B2 Pulley unit 失效
标题翻译：滑轮单元
公开(公告)号：US07100754B2
公开(公告)日：2006-09-05
申请号：US10997877
申请日：2004-11-29
申请人： Yasuhito Tanaka
发明人： Yasuhito Tanaka
IPC分类号： F16D15/00
CPC分类号： F16H55/36 , F16H2055/366
摘要： A pulley unit made by interposing a one-way clutch in an annular space between a pulley and an axial body providing a deep groove ball bearing on a base end side of the one-way clutch, and a roller bearing on the free end side; setting an inner rolling surface of a roller of the one-way clutch to be an outer diameter surface of the axial body and an inner rolling surface of a rolling member of the roller bearing to be an outer diameter surface of the axial body. The pulley unit permits easy position setting of the pulley, so that stabilized lock and free operation can be expected and productivity can be improved.
摘要翻译： 1.一种滑轮单元，其通过在单向离合器的基端侧的滑轮与轴向体之间的环形空间中插入单向离合器和在自由端侧的滚子轴承，将单向离合器的辊的内侧滚动面设定为轴向体的外径面，将滚子轴承的滚动体的内侧滚动面设定为轴向体的外径面。滑轮单元允许滑轮的容易位置设置，从而可以预期稳定的锁定和自由操作，并且可以提高生产率。

6. 发明授权

US06207151B1 Aqueous solution of t-PA 失效
标题翻译： t-PA的水溶液
公开(公告)号：US06207151B1
公开(公告)日：2001-03-27
申请号：US08259152
申请日：1994-06-13
申请人： Yukio Shimazaki , Nobuhiro Kawashima , Miki Suzuki , Yasuhito Tanaka , Ryo Tanaka , Kiyoshi Sakai , Hisahiro Ishiwari
发明人： Yukio Shimazaki , Nobuhiro Kawashima , Miki Suzuki , Yasuhito Tanaka , Ryo Tanaka , Kiyoshi Sakai , Hisahiro Ishiwari
IPC分类号： A61K3849
CPC分类号： A61K38/49 , A61K47/34 , A61K47/36 , A61K47/42
摘要： Aqueous protein-containing solutions, in which a protein is dissolved at a high concentration at a pH near the isoelectric point of the protein by adding an anionic polymer or a salt thereof to the solution. Pharmaceutical formulations using a physiologically active protein are prepared using this technique.
摘要翻译：含有蛋白质的溶液，其中蛋白质通过向溶液中加入阴离子聚合物或其盐，在接近蛋白质等电点的pH下以高浓度溶解。使用该技术制备使用生理活性蛋白质的药物制剂。

7. 发明授权

US4965263A 6-acylaminophenyl-5-alkyl-4,5-dihydro-3(2H)-pyridazinone compounds useful as blood pressure depressants, antithrombotic agents and in the treatment of heart disease 失效
标题翻译：可用作降压药，抗血栓形成剂和治疗心脏病的6-酰基氨基苯基-5-烷基-4,5-二氢-3（2H） - 哒嗪酮化合物
公开(公告)号：US4965263A
公开(公告)日：1990-10-23
申请号：US310505
申请日：1989-02-14
申请人： Takashi Nishina , Joji Kamiya , Yasuhito Tanaka , Tsutomu Katakami , Nobuyuki Fukazawa , Hajime Iizuka , Takuo Nakano
发明人： Takashi Nishina , Joji Kamiya , Yasuhito Tanaka , Tsutomu Katakami , Nobuyuki Fukazawa , Hajime Iizuka , Takuo Nakano
IPC分类号： C07D237/04 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12
CPC分类号： C07D401/12 , C07D237/04 , C07D403/12 , C07D405/12 , C07D409/12
摘要： This invention relates to pyridazinone derivatives of the general formula: ##STR1## [wherein R.sup.1 stands for a hydrogen atom or a lower alkyl group; R.sup.2 for a hydrogen atom or a lower alkyl group; and A for (i) a ring selected from a benzene ring, a furan ring, a thiophene ring and a pyridine ring (on which ring 1-3 substituents or atoms selected from amino groups, nitro groups, lower alkanoylamino groups, hydroxyl groups, lower alkanoyloxy groups, sulfamoyl groups and halogen atoms may be present), or (ii) a grouping of the formula: ##STR2## (wherein R.sup.3 stands for a hydrogen atom, a lower alkyl group, a phenyl(lower)alkyl, a hydroxyphenyl(lower)alkyl group, a lower alkylmercapto(lower)alkyl group, a benzylmercapto(lower)alkyl group, a guanidino(lower)alkyl group, a nitroguanidino(lower)alkyl group, an indolyl(lower)alkyl group, a carbamoyl(lower)alkyl group or a carboxy(lower)alkyl group, R.sup.4 for a hydrogen atom or a lower alkyl group, R.sup.5 for a hydrogen atom, a lower alkyl group, a lower alkanoyl group, a benzoyl or a benzyloxycarbonyl group, and R.sup.3 and R.sup.4 may be combined to form a grouping of the formula: ##STR3## which forms a ring), or (iii) a grouping of the formula: ##STR4## (wherein R.sup.6, R.sup.7 and R.sup.8 each stand for a hydrogen atom or a lower alkyl group, B is an oxygen atom or a sulfur atom, R.sup.9 stands for a hydrogen atom or a lower alkanoyl group, and n is 0 or 1)].

8. 发明申请

US20060040824A1 Nitrogen oxides-removing material and device 审中-公开
标题翻译：氮氧化物去除材料和装置
公开(公告)号：US20060040824A1
公开(公告)日：2006-02-23
申请号：US11207796
申请日：2005-08-22
申请人： Shinichi Ikeda , Norio Umeyama , Hideo Abe , Yasuhito Tanaka , Ariyoshi Ogasawara
发明人： Shinichi Ikeda , Norio Umeyama , Hideo Abe , Yasuhito Tanaka , Ariyoshi Ogasawara
IPC分类号： B01J23/86 , B01J20/00
CPC分类号： B01J23/58 , B01D53/9418 , B01D2251/2062 , B01D2251/208 , B01D2255/1021 , B01D2255/1026 , B01D2255/20707 , B01D2255/20738 , B01D2255/20753 , B01D2255/20784 , B01D2255/9022 , B01D2255/91 , B01J23/002 , B01J35/002 , B01J35/06 , B01J37/0225 , B01J2523/00 , B01J2523/12 , B01J2523/23 , B01J2523/305 , B01J2523/41 , B01J2523/828 , B01J2523/821 , B01J2523/67 , B01J2523/842 , B01J2523/847
摘要： A nitrogen oxides-removing material has fixed onto surfaces of metal fibers a complex compound containing at least one element selected from the group consisting of Group VIII elements, Group IX elements and Group X elements in the periodic table of the elements and at least one element selected from the group consisting of Group I elements, Group II elements, Group XIII elements and Group XIV elements in the periodic table of the elements. A nitrogen oxides-removing device includes the nitrogen oxides-removing material and a means to elevate a temperature of the nitrogen oxides-removing material to than 100° C. or more.
摘要翻译：氮氧化物去除材料已经固定到金属纤维的表面上，该复合化合物含有选自元素周期表中的VIII族元素，第Ⅸ族元素和X族元素中的至少一种元素，并且至少一种元素选自元素周期表中的第I组元素，第II族元素，第XIII族元素和第XIV族元素。氮氧化物去除装置包括氮氧化物去除材料和将氮氧化物去除材料的温度升高至100℃以上的手段。

9. 发明申请

US20050201211A1 Annealing device and annealing method 审中-公开
标题翻译：退火装置和退火方法
公开(公告)号：US20050201211A1
公开(公告)日：2005-09-15
申请号：US10517604
申请日：2004-05-21
申请人： Goro Fujita , Takeshi Miki , Yasuhito Tanaka , Tetsuhiro Sakamoto , Kazuhiko Fujiie
发明人： Goro Fujita , Takeshi Miki , Yasuhito Tanaka , Tetsuhiro Sakamoto , Kazuhiko Fujiie
IPC分类号： G11B11/105 , G11B7/09 , G11B11/00
CPC分类号： G11B11/10582 , G11B11/10523 , G11B11/10576 , G11B11/10595
摘要： The present invention is directed to an annealing apparatus adapted for performing anneal processing with respect to a magneto optical recording medium, which comprises a diffraction optical unit (3) for optically separating light beams emitted from a laser light source (1) into first light beams which are the 0 (zero)-th order diffracted light beams and second and third light beams which are the first order diffracted light beams, an object lens (5) for converging the first light beams to irradiate the first light beams thus converged onto magnetic layers of guide grooves or land portions forming both sides of the guide grooves, and for converging the second and third light beams to irradiate the second and third light beams thus converged onto magnetic layers in the vicinity of the boundary portions between guide grooves and land portions, and a biaxial actuator unit (6) for controlling the object lens (5) on the basis of linear characteristic of a first tracking error signal generated on the basis of intensity distribution of light quantities of rays of return light of the first light beams so that the first light beams follow the guide grooves or the land portions.
摘要翻译：本发明涉及一种用于对磁光记录介质进行退火处理的退火设备，该退火设备包括用于将从激光光源（1）发射的光束光学分离成第一光束的衍射光学单元（3）它们是作为一级衍射光束的0（零）级衍射光束和第二和第三光束，用于会聚第一光束以照射第一光束的物镜（5），从而会聚到磁形成导向槽的两侧的引导槽或台面部分的层，并且用于会聚第二和第三光束以照射第二和第三光束，从而会聚在引导槽和焊盘部分之间的边界部分附近的磁性层上以及用于基于第一跟踪误差符号的线性特性来控制物镜（5）的双轴致动器单元（6）基于第一光束的光量的光的强度分布产生，使得第一光束跟随引导槽或岸台部分。

10. 发明授权

US06169714A Apparatus and method for recording/reproducing magneto-optical information 失效
标题翻译：用于记录/再现磁光信息的装置和方法
公开(公告)号：US06169714A
公开(公告)日：2001-01-02
申请号：US09173069
申请日：1998-10-16
申请人： Yasuhito Tanaka , Masaaki Kurebayashi , Takeshi Maeda , Hitoshi Watanabe , Tetsu Watanabe , Shigemi Maeda , Satoshi Sumi , Nobuhide Matsubayashi , Michio Matsuura
发明人： Yasuhito Tanaka , Masaaki Kurebayashi , Takeshi Maeda , Hitoshi Watanabe , Tetsu Watanabe , Shigemi Maeda , Satoshi Sumi , Nobuhide Matsubayashi , Michio Matsuura
IPC分类号： G11B709
CPC分类号： G11B7/126 , G11B7/094 , G11B7/0941 , G11B7/0945 , G11B7/0956 , G11B11/10515 , G11B11/10576 , G11B11/10595
摘要： A magneto-optical information recording/reproducing apparatus in which a magneto-optical information recording medium at least including a first magnetic film having perpendicular magnetic anisotropy, and a second magnetic film to which information recorded on the first magnetic film is transferred by irradiation of a laser beam, is used so that a readout laser beam is irradiated onto the second magnetic film to thereby readout the information transferred to the second magnetic film. The apparatus includes a 2-split detection circuit for receiving the readout laser beam reflected from the second magnetic film of the recording medium, and a subtraction circuit in which output signals of the two detection elements of the 2-split detection circuit are subtracted from each other to generate a differential signal. The apparatus further comprises a circuit for making a spot of the laser beam jump one track before readout of the information from the magneto-optical information recording medium, a positive/negative balance correction circuit for detecting an amplitude ratio between positive and negative side amplitudes in a track jump signal generated in the differential signal from the subtraction circuit in response to the track jump to thereby output a correction signal in accordance with the amplitude ratio, and an addition circuit for adding the correction signal to the differential signal to thereby generate a tracking error signal for tracking control used in readout of the magneto-optical information from the magneto-optical information recording medium.
摘要翻译：一种磁光信息记录/再现装置，其中至少包括具有垂直磁各向异性的第一磁性膜的磁光信息记录介质和第二磁性膜，通过照射使用激光束，使得读出的激光束照射到第二磁性膜上，从而读出传递到第二磁性膜的信息。该装置包括用于接收从记录介质的第二磁性膜反射的读出激光束的二分割检测电路，以及减法电路，其中从每个减去2分割检测电路的两个检测元件的输出信号另外产生差分信号。该装置还包括一个电路，用于在从磁光信息记录介质读出信息之前使激光束的点跳跃到一个轨道;正/负平衡校正电路，用于检测正，负振幅之间的振幅比，响应于轨道跳跃从减法电路产生的差分信号中产生的轨道跳转信号，从而根据振幅比输出校正信号;以及加法电路，用于将校正信号加到差分信号上，从而产生跟踪用于从磁光信息记录介质读出磁光信息的跟踪控制的误差信号。

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