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    • 31. 发明申请
    • Airflow meter with device for the separation of foreign particles
    • 具有用于分离外来颗粒的装置的气流计
    • US20060137438A1
    • 2006-06-29
    • US10528898
    • 2003-05-23
    • Thomas LenzingKlaus ReymannUwe konzelmannTorsten Schulz
    • Thomas LenzingKlaus ReymannUwe konzelmannTorsten Schulz
    • G01P5/24
    • G01F1/6842G01F5/00G01F15/12
    • A device is provided for determining at least one parameter of a medium flowing in a line in a main flow direction, e.g., a parameter of the intake air mass of an internal combustion engine. The device includes a part, which is inserted into the line at a predetermined alignment with respect to the main flow direction in such a way that a partial flow of the medium flowing in the line in the main flow direction flows through at least one measuring channel provided in the part in a first direction from an intake of the measuring channel to an outlet of the measuring channel. The device further includes a measuring element situated in the measuring channel for determining the at least one parameter. Between its intake and its outlet, the measuring channel features at least one channel segment in which a mechanism is located that causes flow vortices in this channel segment, whereby liquid droplets and solid particles are advantageously deposited on the inner wall of the channel before they can reach the measuring element.
    • 提供了一种装置,用于确定在主流动方向(例如内燃机的进气体的参数)中在一行中流动的介质的至少一个参数。 该装置包括以相对于主流动方向以预定对准的方式插入到管线中的部分,使得在主流动方向上在管线中流动的介质的部分流动流过至少一个测量通道 在第一方向上从测量通道的入口到测量通道的出口设置在该部分中。 该装置还包括位于测量通道中的用于确定至少一个参数的测量元件。 在其入口和出口之间,测量通道具有至少一个通道段,在该通道段中定位有在该通道段中引起流动涡旋的机构,由此液滴和固体颗粒有利地沉积在通道的内壁上, 到达测量元件。
    • 32. 发明授权
    • SMS-initiated mobile registration
    • 短信发起移动注册
    • US09210557B2
    • 2015-12-08
    • US13332308
    • 2011-12-20
    • Rahim Ismail AdatiaIain Andrew HuxleyAlexander Nickolas LindeTorsten SchulzTravis Scott Young
    • Rahim Ismail AdatiaIain Andrew HuxleyAlexander Nickolas LindeTorsten SchulzTravis Scott Young
    • H04W4/14
    • H04W4/14
    • Embodiments are directed towards SMS-initiated mobile registration. A mobile device sends an SMS message to a mobile registration device. In response, the mobile registration device generates a random identifier and associates it with the mobile device identifier of the mobile device. Then, the mobile registration device sends a response SMS message to the mobile device, the response SMS message containing a Uniform Resource Identifier (URI) to a mobile registration web page, where the URI contains the generated random identifier. The mobile device uses the URI to navigate to the mobile registration web page, where additional registration information is provided. The mobile registration device associates the additional registration information with the mobile device based on the generated random identifier included in the URI, and creates a user account based on the mobile number from which the SMS message was received and the additional registration information.
    • 实施例针对SMS发起的移动注册。 移动设备向移动注册设备发送SMS消息。 作为响应,移动注册设备生成随机标识符并将其与移动设备的移动设备标识符相关联。 然后,移动注册装置向移动装置发送响应SMS消息,该响应SMS消息包含移动注册网页的统一资源标识符(URI),其中URI包含所生成的随机标识符。 移动设备使用该URI来导航到提供附加注册信息的移动注册网页。 移动登记装置根据包含在URI中的所生成的随机标识符,将移动装置的附加登录信息与移动装置进行关联,根据接收到SMS消息的移动号码和附加的登记信息,创建用户账户。
    • 33. 发明授权
    • Assays
    • 测定
    • US08906303B2
    • 2014-12-09
    • US12922383
    • 2009-03-16
    • Eugen ErmantrautThomas KaiserJens TuchscheererVico BaierTorsten SchulzAnke Wöstemeyer
    • Eugen ErmantrautThomas KaiserJens TuchscheererVico BaierTorsten SchulzAnke Wöstemeyer
    • G01N21/00B01L3/00
    • G01N33/58B01L3/50273B01L2200/025B01L2200/0684B01L2300/0816B01L2300/0887B01L2300/123B01L2400/0481Y10T436/25
    • A method for assaying a sample for each of multiple analytes is described. The method includes contacting an array of spaced-apart test zones with a liquid sample (e.g., whole blood). The test zones disposed within a channel of a microfluidic device. The channel is defined by at least one flexible wall and a second wall which may or may not be flexible. Each test zone comprising a probe compound specific for a respective target analyte. The microfluidic device is compressed to reduce the thickness of the channel, which is the distance between the inner surfaces of the walls within the channel. The presence of each analyte is determined by optically detecting an interaction at each of multiple test zones for which the distance between the inner surfaces at the corresponding location is reduced. The interaction at each test zone is indicative of the presence in the sample of a target analyte. Capillary structures of the devices or used in the methods may comprise a matrix and the devices may comprise control elements and methods for assaying of sample may use corresponding controlling activities.
    • 描述了用于分析多种分析物中的每一种的样品的方法。 该方法包括使间隔开的测试区域的阵列与液体样品(例如全血)接触。 测试区域设置在微流体装置的通道内。 通道由至少一个柔性壁和可以是柔性的第二壁限定。 每个测试区域包含对各个目标分析物特异的探针化合物。 微流体装置被压缩以减小通道的厚度,其是通道内的壁的内表面之间的距离。 每个分析物的存在通过光学检测在相应位置处的内表面之间的距离减小的多个测试区域中的每一个处的相互作用来确定。 每个测试区域的相互作用表明样品中目标分析物的存在。 装置的毛细结构或方法中使用的毛细管结构可以包括基质,并且装置可以包括控制元件和用于测定样品的方法可以使用相应的控制活动。
    • 34. 发明申请
    • TRANSFORMATION OF MATERIAL INTO AN OPTICALLY MODULATING STATE VIA LASER RADIATION
    • 通过激光辐射将材料转化为光学调制状态
    • US20130316334A1
    • 2013-11-28
    • US13991347
    • 2011-12-02
    • Torsten SchulzDaniel Weicherding
    • Torsten SchulzDaniel Weicherding
    • G01N21/64
    • G01N21/6402B01L3/502707B01L2300/0654B01L2300/168B41M5/24B41M5/26B41M5/267G02C7/021
    • A method for the transformation of material (e.g. plastic material) into an optically modulating state via laser radiation is described. The optically modulating state may be a state in which light is emitted at a different wavelength than it is absorbed. The plastic material to may be a thermoplastic or elastomeric material, or an organic polymer selected from the group consisting of polyethylene, polypropylene, polystyrene, polycarbonate and polycycloolefin. The laser radiation may comprise the application of an amount of energy of about 0.1 nJoule/μm2 to about 100 μJoule/μm2 and/or may comprise a radiation of a wavelength of about 355 nm to about 1064 nm. The optically modulating state of the plastic material may absorb light in a wavelength spectrum of about 380 nm to about 540 nm and/or a wavelength spectrum of about 635 nm to about 655 nm. The optically modulating state of the plastic material may emit light in a wavelength spectrum of about 550 nm to about 800 nm. The transformation of the plastic material may comprise the generation of optically modulating elements on the surface of said plastic material, selected from the group comprising geometrical forms, geometrical pattern, spots, dots, lines, circles, squares, characters, symbols, drawings, barcode and datamatrixcode. The material may be used as component for the manufacture of a device, microfluidic device, system, cartridge or instrument. Based on the employment of the material the usability of a device or system and/or of any procedure, function or method carried out with it or in it may be determined and/or controlled.
    • 描述了通过激光辐射将材料(例如塑料材料)转换成光学调制状态的方法。 光调制状态可以是以与被吸收不同的波长发射光的状态。 塑料材料可以是热塑性或弹性体材料,或选自聚乙烯,聚丙烯,聚苯乙烯,聚碳酸酯和聚环烯烃的有机聚合物。 激光辐射可以包括施加大约0.1nJoule / mum2至大约100μJoule/ mum2的能量的量和/或可以包括约355nm至约1064nm的波长的辐射。 塑料材料的光学调制状态可以吸收约380nm至约540nm的波长光谱和/或约635nm至约655nm的波长光谱的光。 塑料材料的光学调制状态可发射波长范围为约550nm至约800nm的光。 塑料材料的转化可以包括在所述塑料材料的表面上产生光学调制元件,所述材料选自包括几何形状,几何图案,斑点,点,线,圆,正方形,字符,符号,附图,条形码 和datamatrixcode。 该材料可用作制造装置,微流体装置,系统,筒或仪器的部件。 基于使用材料,可以确定和/或控制装置或系统的可用性和/或与其一起执行的任何程序,功能或方法或其中的可用性。
    • 35. 发明申请
    • METHOD FOR A RATIONAL CELL CULTURING PROCESS
    • 方法细胞培养方法
    • US20120190005A1
    • 2012-07-26
    • US13321877
    • 2010-05-27
    • Jochen SchaubTorsten Schulz
    • Jochen SchaubTorsten Schulz
    • C12Q3/00
    • G01N33/5005G01N33/92
    • Biopharmaceutical process development with recombinant protein producing mammalian cells has realized a tremendous increase in both productivity and product yields in the past years. These achievements can be mainly attributed to the advancements in cell line development, media, and process optimization. Only recently, genome-scale technologies enable a system-level analysis to elucidate the complex biomolecular basis of protein production in mammalian cells promising an increased process understanding and the deduction of knowledge-based approaches for further process optimization. The present invention describes a method for a rational cell culturing process using such a knowledge-based approach.
    • 使用重组蛋白质生产哺乳动物细胞的生物制药工艺开发在过去几年中实现了生产力和产品产量的大幅度增长。 这些成果主要归功于细胞培养,培养和工艺优化的进步。 只有最近,基因组技术才能实现系统级分析,以阐明哺乳动物细胞中蛋白质生产的复杂生物分子基础,从而有助于进一步增强过程的理解和推导基于知识的方法进一步优化工艺。 本发明描述了使用这种基于知识的方法进行合理细胞培养过程的方法。
    • 39. 发明授权
    • Airflow meter with device for the separation of foreign particles
    • 具有用于分离外来颗粒的装置的气流计
    • US07260986B2
    • 2007-08-28
    • US10528898
    • 2003-05-23
    • Thomas LenzingKlaus ReymannUwe KonzelmannTorsten Schulz
    • Thomas LenzingKlaus ReymannUwe KonzelmannTorsten Schulz
    • G01F1/68
    • G01F1/6842G01F5/00G01F15/12
    • A device is provided for determining at least one parameter of a medium flowing in a line in a main flow direction, e.g., a parameter of the intake air mass of an internal combustion engine. The device includes a part, which is inserted into the line at a predetermined alignment with respect to the main flow direction in such a way that a partial flow of the medium flowing in the line in the main flow direction flows through at least one measuring channel provided in the part in a first direction from an intake of the measuring channel to an outlet of the measuring channel. The device further includes a measuring element situated in the measuring channel for determining the at least one parameter. Between its intake and its outlet, the measuring channel features at least one channel segment in which a mechanism is located that causes flow vortices in this channel segment, whereby liquid droplets and solid particles are advantageously deposited on the inner wall of the channel before they can reach the measuring element.
    • 提供了一种装置,用于确定在主流动方向(例如内燃机的进气体的参数)中在一行中流动的介质的至少一个参数。 该装置包括以相对于主流动方向以预定对准的方式插入到管线中的部分,使得在主流动方向上在管线中流动的介质的部分流动流过至少一个测量通道 在第一方向上从测量通道的入口到测量通道的出口设置在该部分中。 该装置还包括位于测量通道中的用于确定至少一个参数的测量元件。 在其入口和出口之间,测量通道具有至少一个通道段,在该通道段中定位有在该通道段中引起流动涡旋的机构,由此液滴和固体颗粒有利地沉积在通道的内壁上, 到达测量元件。