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41. 发明授权

US09286261B1 Architecture and method for a burst buffer using flash technology 有权
标题翻译：使用闪存技术的突发缓冲区的架构和方法
公开(公告)号：US09286261B1
公开(公告)日：2016-03-15
申请号：US13676000
申请日：2012-11-13
申请人： EMC Corporation , Los Alamos National Security, LLC
发明人： Percy Tzelnic , Sorin Faibish , Uday K. Gupta , John Bent , Gary Alan Grider , Hsing-bung Chen
IPC分类号： G06F15/167
CPC分类号： G06F15/167 , G06F11/108 , G06F17/30218 , G06F2211/1028
摘要： A parallel supercomputing cluster includes compute nodes interconnected in a mesh of data links for executing an MPI job, and solid-state storage nodes each linked to a respective group of the compute nodes for receiving checkpoint data from the respective compute nodes, and magnetic disk storage linked to each of the solid-state storage nodes for asynchronous migration of the checkpoint data from the solid-state storage nodes to the magnetic disk storage. Each solid-state storage node presents a file system interface to the MPI job, and multiple MPI processes of the MPI job write the checkpoint data to a shared file in the solid-state storage in a strided fashion, and the solid-state storage node asynchronously migrates the checkpoint data from the shared file in the solid-state storage to the magnetic disk storage and writes the checkpoint data to the magnetic disk storage in a sequential fashion.
摘要翻译：并行超级计算集群包括互连在用于执行MPI作业的数据链路的网格中的计算节点，以及每个链接到相应的计算节点组的固态存储节点，用于从相应的计算节点接收检查点数据，以及磁盘存储链接到每个固态存储节点，用于将检查点数据从固态存储节点异步迁移到磁盘存储器。每个固态存储节点向MPI作业呈现文件系统接口，并且MPI作业的多个MPI处理以支路方式将检查点数据写入固态存储器中的共享文件，而固态存储节点将检查点数据从固态存储器中的共享文件异步地迁移到磁盘存储器，并将检查点数据以顺序的方式写入磁盘存储器。

42. 发明授权

US09255923B2 Quantitative multiplex detection of pathogen biomarkers 有权
标题翻译：定量多重检测病原体生物标志物
公开(公告)号：US09255923B2
公开(公告)日：2016-02-09
申请号：US14317378
申请日：2014-06-27
申请人： Los Alamos National Security, LLC
发明人： Harshini Mukundan , Hongzhi Xie , Basil I. Swanson , Jennifer Martinez , Wynne K. Grace
IPC分类号： G01N33/551 , G01N33/569 , G01N33/543 , G01N21/552 , G01N21/77
CPC分类号： G01N33/569 , G01N21/553 , G01N21/774 , G01N33/54373 , G01N2469/00
摘要： The present invention addresses the simultaneous detection and quantitative measurement of multiple biomolecules, e.g., pathogen biomarkers through either a sandwich assay approach or a lipid insertion approach. The invention can further employ a multichannel, structure with multi-sensor elements per channel.
摘要翻译：本发明通过夹心测定方法或脂质插入方法来解决多个生物分子的同时检测和定量测量，例如病原体生物标志物。本发明可以进一步采用每个通道具有多传感器元件的多通道结构。

43. 发明申请

US20160009765A1 BROAD SPECTRUM ANTIBIOTIC COMPOUNDS AND USE THEREOF 有权
标题翻译：广谱光谱抗生素化合物及其用途
公开(公告)号：US20160009765A1
公开(公告)日：2016-01-14
申请号：US14771710
申请日：2014-02-28
申请人： Alexander Koglin , Matthias Strieker
发明人： Alexander Koglin , Matthias Strieker
IPC分类号： C07K9/00
CPC分类号： C07K9/006 , A61K38/00 , C07H17/00 , C07H19/02
摘要： The discovery of a non-ribosomal peptide synthetase (NRPS) gene cluster in the genome of Clostridium thermocellum that produces a secondary metabolite that is assembled outside of the host membrane is described. Also described is the identification of homologous NRPS gene clusters from several additional microorganisms. The secondary metabolites produced by the NRPS gene clusters exhibit broad spectrum antibiotic activity. Thus, antibiotic compounds produced by the NRPS gene clusters, and analogs thereof, their use for inhibiting bacterial growth, and methods of making the antibiotic compounds are described.
摘要翻译：描述了产生在宿主膜外部组装的次级代谢物的热纤维梭菌（Clostridium thermocellum）基因组中非核糖体肽合成酶（NRPS）基因簇的发现。还描述了从几种另外的微生物鉴定同源NRPS基因簇。由NRPS基因簇产生的次级代谢产物显示广谱抗生素活性。因此，描述了由NRPS基因簇产生的抗生素化合物及其类似物，其抑制细菌生长的用途，以及制备抗生素化合物的方法。

44. 发明授权

US09217101B2 Low-melting elemental metal or fusible alloy encapsulated polymerization initiator for delayed initiation 有权
标题翻译：用于延迟引发的低熔点元素金属或易熔合金包封聚合引发剂
公开(公告)号：US09217101B2
公开(公告)日：2015-12-22
申请号：US13081935
申请日：2011-04-07
申请人： Robert E. Hermes
发明人： Robert E. Hermes
IPC分类号： C09K8/40 , C09K3/00
CPC分类号： C09K8/12 , C09K3/00 , C09K8/40
摘要： An encapsulated composition for polymerization includes an initiator composition for initiating a polymerization reaction, and a capsule prepared from an elemental metal or fusible alloy having a melting temperature from about 20° C. to about 200° C. A fluid for polymerization includes the encapsulated composition and a monomer. When the capsule melts or breaks open, the initiator is released.
摘要翻译：用于聚合的包封的组合物包括用于引发聚合反应的引发剂组合物和由熔融温度为约20℃至约200℃的元素金属或熔融合金制备的胶囊。聚合流体包括封装的组合物和单体。当胶囊熔化或断开时，引发剂被释放。

45. 发明授权

US09216144B2 Hair treatment process providing dispersed colors by light diffraction 有权
$Hair treatment process providing dispersed colors by light diffraction$
标题翻译：头发处理工艺通过光衍射提供分散的颜色
公开(公告)号：US09216144B2
公开(公告)日：2015-12-22
申请号：US14229414
申请日：2014-03-28
申请人： The Procter & Gamble Company , Los Alamos National Security LLC
发明人： Richard Matthew Charles Sutton , Bruce Carvell Lamartine , E. Bruce Orler , Shuangqi Song
IPC分类号： A61K8/18 , A61Q5/00 , A61Q5/06 , A61K8/81 , A61K8/85 , A61K8/87 , A45D19/00
CPC分类号： A61Q5/10 , A45D19/00 , A45D19/0008 , A45D2019/0091 , A61K8/18 , A61K8/8129 , A61K8/8152 , A61K8/85 , A61K8/87 , A61K2800/437 , A61K2800/49 , A61Q5/065
摘要： A hair treatment process for providing dispersed colors by light diffraction including (a) coating the hair with a material comprising a polymer, (b) pressing the hair with a pressing device including one or more surfaces, and (c) forming a secondary nanostructured surface pattern on the hair that is complementary to the primary nanostructured surface pattern on the one or more surfaces of the pressing device. The secondary nanostructured surface pattern diffracts light into dispersed colors that are visible on the hair. The section of the hair is pressed with the pressing device for from about 1 to 55 seconds. The polymer has a glass transition temperature from about 55° C. to about 90° C. The one or more surfaces include a primary nanostructured surface pattern.
摘要翻译：一种用于通过光衍射提供分散颜色的毛发处理方法，包括（a）用包含聚合物的材料涂覆毛发，（b）用包括一个或多个表面的加压装置挤压毛发，和（c）形成次级纳米结构表面毛发上的图案与压制装置的一个或多个表面上的初级纳米结构表面图案互补。次级纳米结构表面图案将光衍射成在头发上可见的分散颜色。头发的部分用压制装置按压约1至55秒。聚合物的玻璃化转变温度为约55℃至约90℃。一个或多个表面包括初级纳米结构化表面图案。

46. 发明授权

US09199217B2 Material fabrication using acoustic radiation forces 有权
标题翻译：使用声辐射力的材料制造
公开(公告)号：US09199217B2
公开(公告)日：2015-12-01
申请号：US13047684
申请日：2011-03-14
申请人： Naveen N. Sinha , Dipen N. Sinha , Gregory Russ Goddard
发明人： Naveen N. Sinha , Dipen N. Sinha , Gregory Russ Goddard
IPC分类号： B29B13/08 , B01J19/10 , B01J19/06 , G10K11/165
CPC分类号： B01J19/06 , B01J19/10 , B29C37/00 , B29C2791/008 , B29K2063/00 , B29K2995/0094 , G10K11/165
摘要： Apparatus and methods for using acoustic radiation forces to order particles suspended in a host liquid are described. The particles may range in size from nanometers to millimeters, and may have any shape. The suspension is placed in an acoustic resonator cavity, and acoustical energy is supplied thereto using acoustic transducers. The resulting pattern may be fixed by using a solidifiable host liquid, forming thereby a solid material. Patterns may be quickly generated; typical times ranging from a few seconds to a few minutes. In a one-dimensional arrangement, parallel layers of particles are formed. With two and three dimensional transducer arrangements, more complex particle configurations are possible since different standing-wave patterns may be generated in the resonator. Fabrication of periodic structures, such as metamaterials, having periods tunable by varying the frequency of the acoustic waves, on surfaces or in bulk volume using acoustic radiation forces, provides great flexibility in the creation of new materials. Periodicities may range from millimeters to sub-micron distances, covering a large portion of the range for optical and acoustical metamaterials.
摘要翻译：描述了使用声辐射力来排序悬浮在主液体中的颗粒的装置和方法。颗粒的尺寸范围可以从纳米到毫米，并且可以具有任何形状。将悬浮液放置在声谐振腔中，使用声换能器向其提供声能。所得到的图案可以通过使用可固化的主体液体固化，由此形成固体材料。模式可能很快生成; 典型的时间范围从几秒到几分钟。在一维布置中，形成平行的颗粒层。利用二维和三维换能器布置，由于可能在谐振器中产生不同的驻波图案，所以更复杂的粒子配置是可能的。通过使用声辐射力来改变声波的频率，在表面上或在体积上可调节周期的诸如超材料的周期性结构的制造在新材料的创建方面提供了很大的灵活性。周期可以从毫米到亚微米的距离范围，覆盖光学和声学超材料的大部分范围。

47. 发明授权

US09110178B2 System and method for investigating sub-surface features of a rock formation with acoustic sources generating conical broadcast signals 有权
标题翻译：用于产生锥形广播信号的声源调查岩层的亚表面特征的系统和方法
公开(公告)号：US09110178B2
公开(公告)日：2015-08-18
申请号：US13292935
申请日：2011-11-09
申请人： Cung Khac Vu , Christopher Skelt , Kurt Nihei , Paul A. Johnson , Robert Guyer , James A. Ten Cate , Pierre-Yves Le Bas , Carène S. Larmat
发明人： Cung Khac Vu , Christopher Skelt , Kurt Nihei , Paul A. Johnson , Robert Guyer , James A. Ten Cate , Pierre-Yves Le Bas , Carène S. Larmat
IPC分类号： G01V1/40 , G01V1/44 , G01V1/00 , G01V1/50 , G01V1/46 , G10K15/02 , G01V1/52
CPC分类号： G01V1/006 , G01V1/44 , G01V1/46 , G01V1/50 , G01V1/52 , G01V2210/125 , G01V2210/127 , G01V2210/588 , G10K15/02
摘要： A method of interrogating a formation includes generating a conical acoustic signal, at a first frequency—a second conical acoustic signal at a second frequency each in the between approximately 500 Hz and 500 kHz such that the signals intersect in a desired intersection volume outside the borehole. The method further includes receiving, a difference signal returning to the borehole resulting from a non-linear mixing of the signals in a mixing zone within the intersection volume.
摘要翻译：询问地层的方法包括以第一频率产生锥形声信号 - 第二频率处于大约500Hz和500kHz之间的第二频率的第二锥形声信号，使得信号在钻孔外的期望的相交体积中相交。该方法还包括接收由相交体积内的混合区域中的信号的非线性混合而返回到钻孔的差分信号。

48. 发明授权

US09110024B2 Fiber optical asssembly for fluorescence spectrometry 有权
标题翻译：用于荧光光谱的光纤组件
公开(公告)号：US09110024B2
公开(公告)日：2015-08-18
申请号：US13258727
申请日：2010-03-25
申请人： Martin S. Piltch , Perry Clayton Gray , Richard Rubenstein
发明人： Martin S. Piltch , Perry Clayton Gray , Richard Rubenstein
IPC分类号： G01N21/64 , G01N33/00 , G01N21/65 , G01N33/483
CPC分类号： G01N21/645 , G01N21/65 , G01N33/4833 , G01N2021/6467 , G01N2021/6484
摘要： System is provided for detecting the presence of an analyte of interest in a sample, said system comprising an elongated, transparent container for a sample; an excitation source in optical communication with the sample, wherein radiation from the excitation source is directed along the length of the sample, and wherein the radiation induces a signal which is emitted from the sample; and, at least two linear arrays disposed about the sample holder, each linear array comprising a plurality of optical fibers having a first end and a second end, wherein the first ends of the fibers are disposed along the length of the container and in proximity thereto; the second ends of the fibers of each array are bundled together to form a single end port.
摘要翻译：提供用于检测样品中感兴趣分析物的存在的系统，所述系统包括用于样品的细长透明容器; 与所述样品光学通信的激发源，其中来自所述激发源的辐射沿着所述样品的长度被引导，并且其中所述辐射诱导从所述样品发射的信号; 以及围绕所述样品保持器布置的至少两个线性阵列，每个线性阵列包括具有第一端和第二端的多根光纤，其中所述纤维的所述第一端沿着所述容器的长度并且在其附近设置 ; 每个阵列的纤维的第二端被捆绑在一起以形成单个端口。

49. 发明申请

US20150222619A1 MULTI-FACTOR AUTHENTICATION USING QUANTUM COMMUNICATION 有权
标题翻译：使用量子通信的多因素认证
公开(公告)号：US20150222619A1
公开(公告)日：2015-08-06
申请号：US14424295
申请日：2013-08-16
申请人： Los Alamos National Security, LLC
发明人： Richard John Hughes , Charles Glen Peterson , James T. Thrasher , Jane E. Nordholt , Jon T. Yard , Raymond Thorson Newell , Rolando D. Somma
IPC分类号： H04L29/06 , H04L9/08 , H04L9/32 , G06F21/31
CPC分类号： H04L63/08 , G06F21/31 , G06F2221/2115 , H04L9/0852 , H04L9/3226 , H04L9/3236 , H04L63/083 , H04L2209/38 , H04L2463/082
摘要： Multi-factor authentication using quantum communication (“QC”) includes stages for enrollment and identification. For example, a user enrolls for multi-factor authentication that uses QC with a trusted authority. The trusted authority transmits device factor information associated with a user device (such as a hash function) and user factor information associated with the user (such as an encrypted version of a user password). The user device receives and stores the device factor information and user factor information. For multi-factor authentication that uses QC, the user device retrieves its stored device factor information and user factor information, then transmits the user factor information to the trusted authority, which also retrieves its stored device factor information. The user device and trusted authority use the device factor information and user factor information (more specifically, information such as a user password that is the basis of the user factor information) in multi-factor authentication that uses QC.
摘要翻译：使用量子通信的多因素认证（“QC”）包括登记和识别的阶段。例如，用户注册使用QC与受信任的权限的多因素身份验证。信任机构发送与用户设备（例如散列函数）相关联的设备因素信息和与用户相关联的用户因素信息（例如用户密码的加密版本）。用户设备接收并存储设备因素信息和用户因子信息。对于使用QC的多因素认证，用户设备检索其存储的设备因素信息和用户因素信息，然后将用户因子信息发送到可信管理机构，该信任机构还检索其存储的设备因素信息。在使用QC的多因素认证中，用户设备和受信任的机构使用设备因素信息和用户因素信息（更具体地，诸如作为用户因素信息的基础的用户密码的信息）。

50. 发明授权

US09091517B1 Insensitive detonator apparatus for initiating large failure diameter explosives 有权
标题翻译：用于启动大型故障直径炸药的不敏感雷管装置
公开(公告)号：US09091517B1
公开(公告)日：2015-07-28
申请号：US13722612
申请日：2012-12-20
申请人： LOS ALAMOS NATIONAL SECURITY, LLC
发明人： William Leroy Perry, III
IPC分类号： C06C7/00 , F42C19/00 , F42C19/08 , F42B3/10 , F42B3/113 , F42D1/04
CPC分类号： C06C7/00 , F42B3/10 , F42B3/113 , F42C19/08 , F42C19/0803 , F42C19/0807 , F42C19/0823 , F42C19/0838 , F42D1/04
摘要： A munition according to a preferred embodiment can include a detonator system having a detonator that is selectively coupled to a microwave source that functions to selectively prime, activate, initiate, and/or sensitize an insensitive explosive material for detonation. The preferred detonator can include an explosive cavity having a barrier within which an insensitive explosive material is disposed and a waveguide coupled to the explosive cavity. The preferred system can further include a microwave source coupled to the waveguide such that microwaves enter the explosive cavity and impinge on the insensitive explosive material to sensitize the explosive material for detonation. In use the preferred embodiments permit the deployment and use of munitions that are maintained in an insensitive state until the actual time of use, thereby substantially preventing unauthorized or unintended detonation thereof.
摘要翻译：根据优选实施例的弹药可以包括雷管系统，其具有选择性地耦合到微波源的雷管，该雷管用于选择性地引燃，激活，启动和/或敏化不敏感的爆炸材料用于爆炸。优选的雷管可以包括具有屏障的爆炸腔，其中设置不敏感的爆炸材料和与爆炸腔耦合的波导。优选的系统还可以包括耦合到波导的微波源，使得微波进入爆炸腔并撞击不敏感的爆炸材料，以使爆炸材料致敏以引爆。在使用中，优选实施例允许部署和使用在实际使用时间之前保持在不敏感状态的弹药，从而基本上防止未经授权或意外的爆炸。

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