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41. 发明授权

US07957813B1 Adaptive staged wake-up for implantable medical device communication 有权
标题翻译：用于植入式医疗设备通信的自适应分级唤醒
公开(公告)号：US07957813B1
公开(公告)日：2011-06-07
申请号：US11745651
申请日：2007-05-08
申请人： Benjamin T. Persson , Dorin Panescu , Dean Andersen
发明人： Benjamin T. Persson , Dorin Panescu , Dean Andersen
IPC分类号： A61N1/00
CPC分类号： A61N1/37276
摘要： A communication wake-up scheme for an implantable medical device may involve repeatedly activating a receiver to determine whether an external device is attempting to establish communication with the implantable device. To reduce the amount of power consumed by the implantable device in conjunction with the wake-up scheme, the scheme may involve conducting preliminary radio frequency signal detections as a precursor to conducting a full scan. In this way, power may be conserved since the more power intensive full scans may be performed less frequently. This preliminary detection of radio frequency signals also may be adapted to reduce the number of full scans performed by the implantable device that do not result in communication with the external device. In some embodiments the adaptation involves adjusting one or more thresholds that are used in conjunction with the preliminary detection of radio frequency signals.
摘要翻译：用于可植入医疗设备的通信唤醒方案可以涉及重复激活接收器以确定外部设备是否正在尝试建立与可植入设备的通信。为了结合唤醒方案减少可植入装置消耗的功率量，该方案可以包括进行初步的射频信号检测作为进行全扫描的前兆。以这种方式，可以节省功率，因为可以执行较少的功率密集型全扫描较不频繁。射频信号的这种初步检测也可以适于减少不能导致与外部设备通信的可植入装置执行的全扫描的数量。在一些实施例中，适应涉及调整与射频信号的初步检测结合使用的一个或多个阈值。

42. 发明授权

US07946995B1 Analyzing circadian variations of a hemodynamic parameter to determine an adverse cardiac condition 有权
标题翻译：分析血液动力学参数的昼夜变化以确定不良心脏病
公开(公告)号：US07946995B1
公开(公告)日：2011-05-24
申请号：US11558284
申请日：2006-11-09
申请人： Steve Koh , Euljoon Park , Dorin Panescu
发明人： Steve Koh , Euljoon Park , Dorin Panescu
IPC分类号： A61B5/02
CPC分类号： A61B5/0215 , A61B5/0205 , A61B5/029 , A61B5/0538 , A61B5/1118 , A61B5/4809 , A61B5/686
摘要： A system and method of determining the status of an adverse cardiac condition of a medical patient based on circadian variation of one or more hemodynamic parameters are provided. In some embodiments, the system and method calculate a first average value of a series of first values during a first time period, a second average value of a series of second values during a second time period, and a difference between the first average value and the second average value. The method provides an indication of an adverse cardiac condition when the difference is less than a predetermined threshold.
摘要翻译：提供了一种基于一个或多个血液动力学参数的昼夜变化来确定医疗患者的不良心脏状态的状态的系统和方法。在一些实施例中，系统和方法在第一时间周期期间计算一系列第一值的第一平均值，在第二时间段期间计算一系列第二值的第二平均值，以及第一平均值与第二个平均值。当差小于预定阈值时，该方法提供不良心脏状况的指示。

43. 发明申请

US20110112414A1 SYSTEM FOR AUTOMATED EKG ANALYSIS 审中-公开
标题翻译：自动EKG分析系统
公开(公告)号：US20110112414A1
公开(公告)日：2011-05-12
申请号：US12614354
申请日：2009-11-06
申请人： Dorin Panescu , Bosko Bojovic , Ljupco Hadzievski , Uros Mitrovic , Ihor Gussak
发明人： Dorin Panescu , Bosko Bojovic , Ljupco Hadzievski , Uros Mitrovic , Ihor Gussak
IPC分类号： A61B5/0402
CPC分类号： A61B5/04011
摘要： Systems and methods for analyzing electronic cardiac signals for use in clinical diagnostics are described. System and method embodiments are configured to assist in the analysis of details of EKG signals and vector cardiograms to determine how patients should be categorized into specific cardiac risk categories, such as an acute coronary syndrome category. System configurations may comprise memory devices, computing systems, and EKG data sources positioned at various local or remote positions, and connected via various data connectivity modalities. Various parameters may be utilized to assist in the drawing of one or more conclusions regarding the cardiac condition of a patient.
摘要翻译：描述用于分析用于临床诊断的电子心脏信号的系统和方法。系统和方法实施例被配置为协助分析EKG信号和载体心电图的细节，以确定如何将患者分类为特定的心脏危险类别，例如急性冠状动脉综合征类别。系统配置可以包括位于各种本地或远程位置的存储设备，计算系统和EKG数据源，并经由各种数据连接方式连接。可以使用各种参数来帮助绘制关于患者的心脏状况的一个或多个结论。

44. 发明申请

US20110028821A1 Electrocardiographic Monitoring System and Method Using Orthogonal Electrode Pattern 审中-公开
标题翻译：心电图监测系统及使用正交电极图案的方法
公开(公告)号：US20110028821A1
公开(公告)日：2011-02-03
申请号：US12534064
申请日：2009-07-31
申请人： Bosko Bojovic , Ljupco Hadievski , Dorin Panescu
发明人： Bosko Bojovic , Ljupco Hadievski , Dorin Panescu
IPC分类号： A61B5/0402
CPC分类号： A61B5/0006 , A61B5/04085
摘要： A system for monitoring a cardiac condition of a patient includes a diagnostic center configured to construct a 12-lead ECG of a patient using a special ECG signals numbering less than twelve by combining the special ECG signals with a transformation matrix, and a wearable device configured to generate the special ECG signals and including. The wearable device includes a belt having one or more belt electrodes, a waistband having one or more waistband electrodes, the belt and waistband electrodes configured to contact the skin of the patient and obtain electrical signals therefrom, and a host unit in electrical communication with the belt and waistband electrodes, the host unit including circuitry for generating the special ECG signals from one or more of the acquired electrical signals and circuitry for special ECG signals to a location remote from the wearable device.
摘要翻译：用于监测患者的心脏病状的系统包括诊断中心，诊断中心被配置为通过将特殊ECG信号与变换矩阵相结合，使用小于十二的特殊ECG信号来构建患者的12导联ECG，以及配置的可穿戴设备以产生特殊的ECG信号并包括。所述可穿戴装置包括具有一个或多个皮带电极的带，具有一个或多个腰带电极的腰带，所述皮带和腰带电极被配置为接触患者的皮肤并从其获得电信号;以及主体单元，皮带和腰带电极，所述主机单元包括用于从所获取的电信号中的一个或多个产生特殊ECG信号的电路和用于特殊ECG信号的电路到远离所述可佩戴装置的位置的电路。

45. 发明申请

US20100004712A1 SYSTEMS AND METHODS FOR USE BY AN IMPLANTABLE MEDICAL DEVICE FOR DETECTING HEART FAILURE BASED ON THE INDEPENDENT INFORMATION CONTENT OF IMMITANCE VECTORS 有权
标题翻译：基于独立信息内容的可移植医疗设备用于检测心跳失败的系统和方法
公开(公告)号：US20100004712A1
公开(公告)日：2010-01-07
申请号：US12168750
申请日：2008-07-07
申请人： Wenxia Zhao , Dorin Panescu , Anders Bjorling
发明人： Wenxia Zhao , Dorin Panescu , Anders Bjorling
IPC分类号： A61N1/365
CPC分类号： A61N1/36521 , A61B5/053 , A61B5/0538 , A61N1/3627
摘要： Techniques are provided for detecting heart failure or other medical conditions within a patient using an implantable medical device, such as pacemaker or implantable cardioverter/defibrillator, or external system. In one example, physiological signals, such as immittance-based signals, are sensed within the patient along a plurality of different vectors, and the amount of independent informational content among the physiological signals of the different vectors is determined. Heart failure is then detected by the implantable device based on a significant increase in the amount of independent informational content among the physiological signals. In response, therapy may be controlled, diagnostic information stored, and/or warning signals generated. In other examples, at least some of these functions are performed by an external system.
摘要翻译：提供了用于使用可植入医疗装置（例如起搏器或植入式心律转复器/去纤颤器或外部系统）来检测患者心脏衰竭或其他医疗状况的技术。在一个示例中，沿着多个不同的向量在患者体内感测诸如基于导纳的信号的生理信号，并且确定不同矢量的生理信号中的独立信息内容的量。基于生理信号中独立信息内容量的显着增加，可植入装置检测心力衰竭。作为响应，可以控制治疗，存储诊断信息和/或生成警告信号。在其他示例中，这些功能中的至少一些由外部系统执行。

46. 发明授权

US07582084B2 Systems and methods for controlling power in an electrosurgical probe 有权
公开(公告)号：US07582084B2
公开(公告)日：2009-09-01
申请号：US10303079
申请日：2002-11-22
申请人： David K Swanson , Robert Burnside , James G. Whayne , Dorin Panescu
发明人： David K Swanson , Robert Burnside , James G. Whayne , Dorin Panescu
IPC分类号： A61B18/12
CPC分类号： A61B18/1206 , A61B18/1492 , A61B2018/0016 , A61B2018/00351 , A61B2018/00577 , A61B2018/00654 , A61B2018/0069 , A61B2018/00702 , A61B2018/00714 , A61B2018/00726 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/00821 , A61B2018/00875 , A61B2018/124 , A61B2018/1253 , A61B2018/128 , A61B2018/1467
摘要： Systems and methods for controlling the power supplied to an electrosurgical probe. The systems and methods may be used to monitor electrode-tissue contact, adjust power in response to a loss of contact, and apply power in such a manner that charring, coagulum formation and tissue popping are less likely to occur.

47. 发明申请

US20070073286A1 Method and apparatus for an ocular procedure 审中-公开
标题翻译：眼部手术的方法和装置
公开(公告)号：US20070073286A1
公开(公告)日：2007-03-29
申请号：US11242430
申请日：2005-09-29
申请人： Dorin Panescu , Chris Ikei , Larry Hood
发明人： Dorin Panescu , Chris Ikei , Larry Hood
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B2018/143 , A61F9/0079 , A61F2009/00872
摘要： A system for denaturing corneal tissue. The system includes a ground element and an electrode coupled to a power unit. The electrode is inserted into a cornea. The power unit provides power to the electrode to denature corneal tissue. The power may be at a level so that the temperature of the corneal tissue adjacent to the electrode is such that it minimizes tissue overheating. The power may be applied for a time duration up to 30 seconds at a level that does not exceed 500 mW. The surgeon may dial in an input parameter that correlates with a diopter correction in a cornea.
摘要翻译：角膜组织变性系统。该系统包括接地元件和耦合到功率单元的电极。将电极插入角膜。动力单元为电极提供电力以使角膜组织变性。功率可以处于水平，使得与电极相邻的角膜组织的温度使得其最小化组织过热。该功率可以在不超过500mW的水平下施加长达30秒的持续时间。外科医生可以拨入与角膜屈光度矫正相关的输入参数。

48. 发明申请

US20060089688A1 Method and apparatus to reduce wrinkles through application of radio frequency energy to nerves 审中-公开
标题翻译：通过将射频能量应用于神经来减少皱纹的方法和装置
公开(公告)号：US20060089688A1
公开(公告)日：2006-04-27
申请号：US10973170
申请日：2004-10-25
申请人： Dorin Panescu
发明人： Dorin Panescu
IPC分类号： A61F2/00
CPC分类号： A61B18/1477 , A61B2018/0016 , A61B2018/00434 , A61B2018/00452 , A61B2018/143
摘要： An apparatus and method for reducing wrinkles in the skin tissue of a patient. The method includes detecting a nerve. The nerve can be detected by inserting an electrode into the skin tissue, delivering a current and then observing any stimulation of muscle tissue. The process of inserting the electrode, delivering current and detecting muscle stimulation may be repeated at a plurality of different skin location to trace the nerve. Once the nerve is traced, the electrode can be inserted into the skin at various locations, either at or adjacent to the nerve, and deliver energy into the tissue at a level sufficient to disrupt interaction between the nerve and the adjacent muscle. Once the nerve/muscle interaction is disrupted the muscle will be relaxed and the wrinkle(s) will either be removed or reduced.
摘要翻译：一种减轻患者皮肤组织皱纹的装置和方法。该方法包括检测神经。可以通过将电极插入皮肤组织中，传递电流然后观察肌肉组织的任何刺激来检测神经。可以在多个不同的皮肤位置重复插入电极，传递电流和检测肌肉刺激的过程以追踪神经。一旦跟踪了神经，电极可以在神经的或毗邻神经的各个位置插入皮肤，并以足以破坏神经和相邻肌肉之间相互作用的水平将能量递送到组织中。一旦神经/肌肉相互作用被破坏，肌肉就会松弛，皱纹会被去除或减少。

49. 发明申请

US20050245949A1 Thermokeratoplasty system with a guided probe tip 审中-公开
标题翻译：具有导向探针尖端的热机器人成形系统
公开(公告)号：US20050245949A1
公开(公告)日：2005-11-03
申请号：US10834677
申请日：2004-04-28
申请人： Paul Goth , Dorin Panescu , Steve Khalaj
发明人： Paul Goth , Dorin Panescu , Steve Khalaj
IPC分类号： A61F9/00 , A61F9/013
CPC分类号： A61F9/013 , A61F9/0136
摘要： A template that is used with a probe to perform a medical procedure on a cornea. One embodiment of the template includes one or more openings that are used to align the probe with locations of the cornea that are to be denatured with energy transferred by the probe. By way of example, the openings may be located at 6, 7 and 8 millimeters about the center of the cornea. The denatured spots may collectively decrease the radius of curvature of the cornea. The template may have a bottom surface that conforms to the shape of the cornea. The template may have a centering feature that is used to center the template on the cornea and a vacuum channel that maintains the position of the template. The template openings may have stop features that limit a penetration depth of the probe.
摘要翻译：与探头一起使用以在角膜上执行医疗程序的模板。模板的一个实施例包括一个或多个开口，其用于将探针与要被变性的角膜的位置与由探针传送的能量对准。作为示例，开口可以位于角膜中心的6,7和8毫米处。变性斑点可以共同地减小角膜的曲率半径。模板可以具有与角膜的形状一致的底面。模板可以具有定心特征，其用于将模板定位在角膜上，以及保持模板位置的真空通道。模板开口可以具有限制探针的穿透深度的停止特征。

50. 发明授权

US06746401B2 Tissue ablation visualization 有权
标题翻译：组织消融可视化
公开(公告)号：US06746401B2
公开(公告)日：2004-06-08
申请号：US10139994
申请日：2002-05-06
申请人： Dorin Panescu
发明人： Dorin Panescu
IPC分类号： A61B800
CPC分类号： A61B8/483 , A61B8/12 , A61B8/481 , A61B18/1492 , A61B34/20 , A61B2090/378
摘要： Systems and methods for visualizing ablation lesions are provided. A contrast agent is injected into an artery that feeds blood to tissue surrounding an ablation lesion. During or after contrast agent injection, the ablation lesion and surrounding tissue is imaged using an imager that is responsive to the injected contrast agent. In one non-limiting embodiment, the contrast agent comprises echogenic particles, e.g., echogenic microbubbles, and the imager is an ultrasound imager.
摘要翻译：提供了用于可视化消融病变的系统和方法。将造影剂注射到将血液供给到消融病变周围的组织的动脉中。在造影剂注射期间或之后，使用对注入的造影剂作出响应的成像器来成像消融病变和周围组织。在一个非限制性实施方案中，造影剂包括回声颗粒，例如回声微泡，并且成像器是超声波成像器。

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