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51. 发明申请

US20090171305A1 COMBINATION THERAPY FOR LONG-LASTING CKR 审中-公开
标题翻译：长期CKR的组合治疗
公开(公告)号：US20090171305A1
公开(公告)日：2009-07-02
申请号：US12159860
申请日：2007-01-04
申请人： Sami G. El Hage
发明人： Sami G. El Hage
IPC分类号： A61F9/013 , A61F9/00
CPC分类号： A61F2/145 , A61F2/14 , A61F9/0017 , A61F9/007 , G02C7/047 , G02C2202/24
摘要： Corneal collagen crosslinking of CKR™-treated cornea results in a long-lasting, potentially permanent correction of corneal shape and improved vision.
摘要翻译： CKR（TM）角膜的角膜胶原交联导致角膜形状和视力改善的持久，潜在的永久校正。

52. 发明申请

US20090038626A1 Refractive vision correction for preventing presbyopia 审中-公开
$Refractive vision correction for preventing presbyopia$
标题翻译：用于预防老花眼的屈光视力矫正
公开(公告)号：US20090038626A1
公开(公告)日：2009-02-12
申请号：US11836272
申请日：2007-08-09
申请人： Iku Kuo
发明人： Iku Kuo
IPC分类号： A61F9/013
CPC分类号： A61F9/013
摘要： The present invention relates to a refractive vision correction for preventing presbyopia; in particular, to the common refractive vision correction of dealing with myopia, hyperopia or astigmatism such as the problems of seeing for far distance objects, which is applied to and within a corresponding area of the center of the cornea when the pupil is in a size which is under normal light condition, and furthermore, other circular wavy corrections are orderly applied in accordance with different presbyopia degree to the scope beyond said corresponding area and overlapped by another corresponding area of the cornea when the pupil is in its most dilation; therefore, the present invention of pre-performing the circular wavy corrections can provide the patient with plural number of different curves of correction for preventing presbyopia when the patient get older with failing eyesight. The different curves of correction can appropriately improve and remedy the vision for the patient to see nearby objects when in different age with different presbyopia degree and achieve the expected goal of preventing presbyopia.
摘要翻译：本发明涉及一种用于预防老花眼的屈光视力矫正; 特别涉及处理近视，远视或散光的常见的屈光矫正矫正，例如当远距离物体看到的问题时，当瞳孔处于大小时，其应用于角膜中心的相应区域内并在角膜中心的相应区域内其处于正常光照条件下，此外，其他圆形波浪校正根据不同的老花眼程度有序地应用于超过所述对应区域的范围，并且当瞳孔处于最大扩张时与角膜的另一对应区域重叠; 因此，预处理圆形波浪校正的本发明可以为患者提供多个不同的校正曲线，以便在患者视力下降变老时防止老花眼。校正的不同曲线可以适当地改善和补救患者在不同年龄的不同老花眼度下观察附近物体的视力，并达到预防老花眼的预期目标。

53. 发明申请

US20070129802A1 Composition and method for producing shapable implants in vivo and implants produced thereby 审中-公开
标题翻译：用于生产体内可成形植入物的组合物和方法以及由此产生的植入物
公开(公告)号：US20070129802A1
公开(公告)日：2007-06-07
申请号：US11598168
申请日：2006-11-10
申请人： Jagdish Jethmalani , Shiao Chang , Robert Grubbs , Julia Kornfield , Daniel Schwartz , Christian Sandstedt , F. Christ
发明人： Jagdish Jethmalani , Shiao Chang , Robert Grubbs , Julia Kornfield , Daniel Schwartz , Christian Sandstedt , F. Christ
IPC分类号： A61F2/16 , B29D11/00 , A61F9/013
CPC分类号： A61F2/16 , A61F2/1613 , A61F2/1616 , A61F2/1627 , A61F2/1635 , A61F2002/1699 , A61L27/14 , A61L27/50 , A61L2430/16 , B29D11/00009 , B29D11/00355 , B29D11/023 , G02C7/02 , G02C2202/14
摘要： The present invention relates to a method for creating shaped implants, such as intraocular lenses in vivo, as well as the novel implants themselves. Utilizing the method of the invention, it is possible to create an implant in vivo and to adjust either the physical properties such as refractive index, viscosity, etc., mechanical properties such as modulus, tensile strength, tear, etc., or the shape of the implant by noninvasive means. For example, using the method of the patent it is possible to create an intraocular lens in vivo and then adjust the shape and power of the lens through no invasion means. The novel implants are also addressed in this application.
摘要翻译：本发明涉及一种用于产生成形植入物的方法，例如体内的眼内透镜，以及新颖的植入物本身。利用本发明的方法，可以在体内产生植入物，并且可以调节诸如折射率，粘度等的物理性质，模量，拉伸强度，撕裂等的机械性能或形状的植入物通过无创手段。例如，使用该专利的方法，可以在体内产生眼内透镜，然后通过无侵入手段来调整透镜的形状和功率。本申请中还提到了新颖的植入物。

54. 发明申请

US20070129286A1 Treatment Solution and Method for Preventing Posterior Capsular Opacification by Selectively Inducing Detachment And/Or Death of Lens Epithelial Cells 有权
标题翻译：通过选择性诱导镜片上皮细胞分离和/或死亡预防后囊肿不通的治疗方法和方法
公开(公告)号：US20070129286A1
公开(公告)日：2007-06-07
申请号：US11620981
申请日：2007-01-08
申请人： Jin Jun Zhang
发明人： Jin Jun Zhang
IPC分类号： A61F9/013 , A61F2/16 , A61K38/14 , A61K38/23 , A61K31/70 , A61K31/704 , A61K31/7012 , A61K31/685 , A61K31/549 , A61K31/185
CPC分类号： A61K31/185 , A61K9/0048 , A61K31/045 , A61K31/198 , A61K31/70 , A61K2300/00
摘要： A treatment solution used to prevent posterior capsular opacification is applied or introduced into the lens capsular bag before, during, or after cataract surgery. The treatment solution comprises an ion transport mechanism interference agent, which either alone or in combination with other treatment agents such as an osmotic stress agent and an agent to establish a suitable pH, selectively induces detachment and/or death of lens epithelial cells such that posterior capsular opacification is prevented. While the ion transport mechanism interference agent is capable of interfering with the cellular mechanisms and cell ion distribution of a broad range of cells, a concentration of agent is selected such that the treatment solution interferes selectively with the cellular mechanisms of lens epithelial cells while leaving other ocular cells substantially unharmed. The treatment solution selectively induces cellular death and/or detachment of lens epithelial cells while other ocular cells and tissue remain substantially unharmed and without lengthy preoperative pre-treatment.
摘要翻译：在白内障手术之前，期间或之后，使用用于防止后囊膜混浊的治疗溶液或引入镜片囊袋中。治疗溶液包括离子传递机制干扰剂，其单独或与其它治疗剂如渗透应激剂和用于建立合适pH的药剂组合，选择性地诱导晶状体上皮细胞的分离和/或死亡，使得后阻止荚膜混浊。虽然离子传递机制干扰剂能够干扰细胞的细胞机制和细胞离子分布范围广泛的细胞，选择剂的浓度使得治疗溶液选择性干扰晶状体上皮细胞的细胞机制，同时离开其他眼细胞基本上没有受到伤害。治疗溶液选择性地诱导晶状体上皮细胞的细胞死亡和/或分离，而其他眼部细胞和组织基本上没有受伤，并且没有长时间的术前预处理。

55. 发明申请

US20070106376A1 Method and apparatus for enhanced corneal accommodation 有权
标题翻译：增强角膜适应的方法和装置
公开(公告)号：US20070106376A1
公开(公告)日：2007-05-10
申请号：US10572084
申请日：2004-10-06
申请人： Cynthia Roberts , Edwin Sarver , James Marous
发明人： Cynthia Roberts , Edwin Sarver , James Marous
IPC分类号： A61F2/14 , A61F9/013
CPC分类号： A61B3/0025 , A61F9/00808 , A61F9/00821 , A61F9/00838 , A61F9/013 , A61F2009/00853 , A61F2009/00857 , A61F2009/00872 , A61F2009/00895
摘要： A method and apparatus related to enhancing corneal accommodation to address the effect of presbyopia. Corneal/scleral topology measurements in accommodating and non-accommodating states are indicative of a presbyopic subject's nominal corneal accommodative power. A desired accommodative power intended to improve on the effect of presbyopia can be determined, suggesting a selective biomechanical intervention in the corneal structure outside of the optical zone to create flexure regions. These flexure regions would allow enhanced corneal accommodation upon presentation of an accommodating stimulus. Intervention could be in the form of, for example, corneal surface ablation, intrastromal ablation, conductive keratoplasty (CK), laser thermal keratoplasty (LTK), and corneal and/or scleral implants. An improved topology measuring apparatus having an improved field of view and other attributes is disclosed.
摘要翻译：一种与增强角膜适应度相关的方法和装置，以解决老花眼的影响。适应状态和不适应状态下的角膜/巩膜拓扑结构测量表明老花眼受试者的标称角膜调节能力。可以确定旨在改善老花眼效果的期望的调节力，这表明在光学区域外的角膜结构中的选择性生物力学干预以产生弯曲区域。这些挠曲区域将允许在呈现适应刺激时增强角膜适应。干预可以是例如角膜表面消融，基质内消融，导电角膜移植术（CK），激光热角膜移植术（LTK）和角膜和/或巩膜植入物的形式。公开了具有改进的视野和其他属性的改进的拓扑测量装置。

56. 发明申请

US20070016292A1 Epithelium treatment methods and devices for treating the epithelium 审中-公开
标题翻译：用于治疗上皮的上皮治疗方法和装置
公开(公告)号：US20070016292A1
公开(公告)日：2007-01-18
申请号：US11434725
申请日：2006-05-15
申请人： Edward Perez
发明人： Edward Perez
IPC分类号： A61F2/14 , A61F9/013 , G02C7/04
CPC分类号： A61F9/0133
摘要： In general, the devices and methods described herein are useful in the field of ophthalmology. More particularly, the described methods and devices are useful in the field of refractive eye procedures, such as may be practiced when lifting or separating a portion of the epithelial layer or forming a pocket in the epithelial layer of the when introducing a contact lens beneath the epithelium or in conjunction with a corrective ocular laser treatment.
摘要翻译：通常，本文描述的装置和方法在眼科领域是有用的。更具体地，所描述的方法和装置在屈光眼手术领域是有用的，例如可以在提起或分离上皮层的一部分时形成上皮层中的口袋，或者当将隐形眼镜引入上皮或与矫正性眼部激光治疗相结合。

57. 发明申请

US20060254602A1 Method of removing unwanted deposits from a keratoprosthesis in vivo 审中-公开
标题翻译：从体内角质假体去除不需要的沉积物的方法
公开(公告)号：US20060254602A1
公开(公告)日：2006-11-16
申请号：US11405252
申请日：2006-04-17
申请人： Dan Myer
发明人： Dan Myer
IPC分类号： A61F9/013 , A61F2/14
CPC分类号： A61B90/70 , A61F9/0017 , A61F9/007
摘要： A method of applying a solution in vivo made up of chelating agent(s) such as enzymes and/or surfactants in such a composition to the anterior surface of a keratoprosthesis as to remove deposits and unwanted debris from its surface while maintaining the integrity of the keratoprosthesis.
摘要翻译：将由这种组合物中的螯合剂如酶和/或表面活性剂组成的体内溶液施用于角膜假体的前表面的方法，以从其表面去除沉积物和不想要的碎屑，同时保持其完整性角膜假体

58. 发明申请

US20060229633A1 Methods and apparatus for inserting an intraocular lens into an eye 有权
标题翻译：将眼内透镜插入眼睛的方法和装置
公开(公告)号：US20060229633A1
公开(公告)日：2006-10-12
申请号：US11102194
申请日：2005-04-08
申请人： David Shepherd
发明人： David Shepherd
IPC分类号： A61F9/013
CPC分类号： A61F2/1667
摘要： Apparatus and methodology for inserting an intraocular lens (IOL) into an eye. The apparatus includes a cartridge for holding an IOL and a handpiece with a body member for receiving the cartridge, an injector rod that is receivable by the body member, and a drive mechanism that longitudinally oscillates the injector rod in the body member when a rotational force is applied about a longitudinal axis in a single direction. In other words, a constant rotation in a single direction of the drive mechanism causes the injector rod to move distally and proximally in discrete increments, with the distal increments being larger than the proximal increments. Accordingly, the injector rod urges an IOL out of the handpiece in a two-steps-forward, one-step-back manner, thereby minimizing or eliminating the chance of the injector rod engaging with the IOL.
摘要翻译：将眼内透镜（IOL）插入眼睛的装置和方法。该装置包括用于保持IOL的盒和具有用于容纳盒的主体构件的手持件，可由主体构件接收的注射杆;以及驱动机构，其当所述主体构件的旋转力围绕纵向轴线施加在单个方向上。换句话说，在驱动机构的单个方向上的恒定旋转导致喷射器杆以离散的增量向远侧和近侧移动，远端的增量大于近端的增量。因此，注射器杆以两步向前，一步回送的方式将IOL推出手持件，从而最小化或消除了注射器杆与IOL接合的机会。

59. 发明授权

US07101397B2 IOL Implantation 有权
标题翻译： IOL植入
公开(公告)号：US07101397B2
公开(公告)日：2006-09-05
申请号：US10638396
申请日：2003-08-12
申请人： Eli Aharoni
发明人： Eli Aharoni
IPC分类号： A61F2/16 , A61F9/013
CPC分类号： A61F2/1648 , A61F2/1662 , A61F2250/0063
摘要： A method for implanting a new intraocular lens (IOL) in an eye without removing the existing IOL, comprising forming a mounting hole in an IOL already implanted in an eye, and mounting another IOL in the mounting hole. Apparatus is also disclosed including a first IOL formed with a mounting hole, and a second IOL mounted in the mounting hole.
摘要翻译：一种用于在眼睛内植入新的眼内透镜（IOL）而不去除现有IOL的方法，包括在已经植入眼中的IOL中形成安装孔，并将另一个IOL安装在安装孔中。还公开了包括形成有安装孔的第一IOL和安装在安装孔中的第二IOL的装置。

60. 发明申请

US20060173540A1 Intraocular lens and injector for the same 有权
标题翻译：人工晶状体和注射器相同
公开(公告)号：US20060173540A1
公开(公告)日：2006-08-03
申请号：US10547247
申请日：2004-03-26
申请人： Patrice Vincent
发明人： Patrice Vincent
IPC分类号： A61F9/013 , A61F2/16
CPC分类号： A61F2/1613 , A61F2/1616 , A61F2/1664
摘要： An injectable intraocular lens (10) made of flexible material, said lens (10) having an optical portion (11) that is preferably of approximately circular shape, said injectable intraocular lens being characterized in that it also has two side flats (15) provided on opposite edges of the optical portion (11), said flats (15) forming an angle relative to each other.
摘要翻译：一种由柔性材料制成的可注射眼内透镜（10），所述透镜（10）具有优选为大致圆形的光学部分（11），所述可注射眼内透镜的特征在于还具有两个侧平面（15）在光学部分（11）的相对边缘上，所述平面（15）相对于彼此形成一个角度。

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