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    • 63. 发明授权
    • Polyfluorosulfonamido amine and intermediate
    • 多氟磺酰胺和中间体
    • US08258341B2
    • 2012-09-04
    • US12500817
    • 2009-07-10
    • Alexander Borisovich ShtarovPeter Michael MurphyBrent Ryan GonskaStephan James McLain
    • Alexander Borisovich ShtarovPeter Michael MurphyBrent Ryan GonskaStephan James McLain
    • C07C311/09
    • C07C311/09C07C303/38C07C303/40
    • Current methods for making polyfluorosulfonamido amines, which involve the use of a diamine reactant, provide low yields and produce an undesirable fluorine containing bis-sulfonamide by-product representing an economic loss. The bis-sulfonamide by-product is particularly undesirable because it shares very similar physical properties with the desired monoamine product thus making isolation of the desired polyfluorosulfonamido amine product difficult and costly. Furthermore, instead of the efficient incorporation of fluorine to make the desired polyfluorosulfonamido amine product, the bis-sulfonamide by-product constitutes a substantial loss of costly fluorinated starting material. The bis-sulfonamide by-product also constitutes an undesirable impurity that can worsen surfactancy, repellency, or other performance characteristics of the desired polyfluorosulfonamido amine product. The present invention provides a method of making a polyfluorosulfonamido amine without the production of a bis-sulfonamide by-product by reacting a polyfluoroalkylsulfonic compound with a monoamino amide rather than with a diamine reactant as in previously known methods.
    • 涉及使用二胺反应物的制备多氟磺酰氨基胺的现有方法提供低产率并产生表示经济损失的不希望的含氟双磺酰胺副产物。 双磺酰胺副产物是特别不希望的,因为它与所需的单胺产物分享非常相似的物理性质,从而使所需的多氟磺酰胺胺产物的分离困难且昂贵。 此外,代替有效地引入氟以制备所需的多氟磺酰氨基胺产物,双磺酰胺副产物构成昂贵的氟化原料的显着损失。 双磺酰胺副产物也构成可恶化期望的多氟磺酰氨基胺产物的表面活性,排斥性或其它性能特征的不期望的杂质。 本发明提供了如先前已知的方法,通过使多氟烷基磺酸化合物与单氨基酰胺而不是二胺反应物反应而制备多氟磺酰胺,不产生双磺酰胺副产物的方法。
    • 70. 发明申请
    • COMPOSITIONS COMPRISING 2,3,3,3-TETRAFLUOROPROPENE, 2-CHLORO-2,3,3,3-TETRAFLUOROPROPANOL, 2-CHLORO-2,3,3,3-TETRAFLUORO-PROPYL ACETATE OR ZINC (2-CHLORO-2,3,3,3-TETRAFLUOROPROPOXY) CHLORIDE
    • 包含2,3,3,3-四氢呋喃,2-氯-2,3,3,3-四氢氟丙醇,2-氯-2,2,3,3-四氢丙酸乙酯或ZINC(2-氯-2)的组合物 3,3,3-TETRAFLOOROPROPOXY)氯化物
    • US20120168672A1
    • 2012-07-05
    • US13405657
    • 2012-02-27
    • Mario Joseph NappaXuehui Sun
    • Mario Joseph NappaXuehui Sun
    • C09K5/00
    • C09K5/045C09K2205/126
    • Compositions comprising CF3CClFCH2OH, CF3CClFCH2OZnCl, and CF3CClFCH2OC(═O)CH3 are useful in processes to make HFO-1234yf. Compositions comprising HFO-1234yf may comprise at least one additional compound selected from the group consisting of CFC-114a, HCFC-124, HFC-143a, CFO-1113, HFO-1123, HFO-1132a, tetrafluoroethene, HCFO-1122, 3,4,4,4-tetrafluoro-2-butanone, acetyl fluoride, 2-chloro-2,3,3,3-tetrafluoropropanol, 2-chloro-2,3,3,3-tetrafluoropropyl acetate, Zinc (2-chloro-2,3,3,3-tetrafluoropropoxy)chloride, 2-chloro-2,3,3,3-tetrafluoropropoxy methyl acetate, 1,3-bistrifluoromethyl-1,3-difluorocyclobutane, 2,3,3,3-tetrafluoropropyl acetate, dimethylformamide, pyridine, ethyl acetate, acetic acid, diethyl ether, acetic anhydride, methyl acetate, dimethylacetamide, methanol, ethanol, methyl formate, pyrazine, pyrimidine, N-methylpyrrolidine, N-methylpiperidine, hexamethylphosphoramide, tetrahydrofuran, 1,4-dioxane, N-methylpyrrolidinone, dimethyl sulfoxide, acetonitrile, benzonitrile, and mixtures thereof. Compositions comprising HFO-1234yf are useful, among other uses, as heat transfer compositions for use in refrigeration, air-conditioning and heat pump systems.
    • 包含CF 3 CClFCH 2 OH,CF 3 CClFCH 2 OZnCl和CF 3 CClFCH 2 OC(= O)CH 3的组合物可用于制备HFO-1234yf的方法中。 包含HFO-1234yf的组合物可以包含至少一种选自CFC-114a,HCFC-124,HFC-143a,CFO-1113,HFO-1123,HFO-1132a,四氟乙烯,HCFO-1122,3, 4,4,4-四氟-2-丁酮,乙酰氟,2-氯-2,3,3,3-四氟丙醇,2-氯-2,3,3,3-四氟丙基乙酸酯,锌(2-氯 - 2,3,3,3-四氟丙氧基)氯化物,2-氯-2,3,3,3-四氟丙氧基甲酸乙酯,1,3-双三氟甲基-1,3-二氟环丁烷,乙酸2,3,3,3-四氟丙酯 吡啶,乙酸乙酯,乙酸甲酯,二甲基乙酰胺,甲醇,乙醇,甲酸甲酯,吡嗪,嘧啶,N-甲基吡咯烷,N-甲基哌啶,六甲基磷酰胺,四氢呋喃,1,4-二恶烷 ,N-甲基吡咯烷酮,二甲基亚砜,乙腈,苄腈及其混合物。 包括HFO-1234yf的组合物在其它用途中可用作用于制冷,空调和热泵系统的热传递组合物。