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71. 发明授权

US11470068B2 System and methods for securely storing data for efficient access by cloud-based computing instances 有权
公开(公告)号：US11470068B2
公开(公告)日：2022-10-11
申请号：US15931417
申请日：2020-05-13
申请人： PricewaterhouseCoopers LLP
发明人： Praveen Vasireddy , Sriraj Kadimisetty , Michael Flynn , Michael Baccala , Vinod K. Kandepi , Shiva Sadula
IPC分类号： H04L29/06 , H04L9/40 , G06F21/62
摘要： Systems and methods for securely storing data for efficient access by cloud-based computing instances is provided. In one or more examples, a computing hub can receive one or more access requests to data stored within a persistent data storage computing resources that in connected to the computing hub. The computing hub can be configured to determine if the access request is from an authorized computing resource, and can then generate one or more tokens that provide access to the computing resource. The one or more tokens can include information regarding the IP address of the requesting cloud-based computing resource, and each time that the cloud-based computing resource uses the token to request access to the stored data, the computing hub can check the IP address of the computing resource against the IP address indicated on the token to decide whether or not to grant access to the data.

72. 发明授权

US11467589B2 Methods and systems for generating shared collaborative maps 有权
公开(公告)号：US11467589B2
公开(公告)日：2022-10-11
申请号：US16701647
申请日：2019-12-03
申请人： Climate LLC
发明人： Doug Sauder , Tavis Bones , Tim Reddy
IPC分类号： G05D1/02 , A01B79/00 , A01C7/08 , A01C21/00 , A01D41/127
摘要： Described herein are methods and systems for generating shared collaborative maps for planting or harvesting operations. A method of generating a collaborative shared map between machines includes generating a first map for a first machine based on a first set of data and generating a second map for a second machine based on a second set of data. The method further includes generating at least one shared collaborative map for at least one of the first and second machines based on the first and second maps.

73. 发明授权

US11465764B2 Systems and methods for power distribution in electric aircraft 有权
公开(公告)号：US11465764B2
公开(公告)日：2022-10-11
申请号：US17115119
申请日：2020-12-08
申请人： Archer Aviation, Inc.
发明人： John Melack
IPC分类号： E05F15/77 , B60R16/00 , B60R16/02 , B64D27/24 , B64C29/00
摘要： A electric aircraft power distribution system includes a first battery pack connected to at least a first load and to a common bus that connects the first battery pack in parallel to at least a second battery pack; a first electrical component electrically connected between the first battery pack and the first load and configured to disconnect the first load from the first battery pack in response to current above a first threshold current, wherein the first electrical component has a first disconnection time at the first threshold current; and a second electrical component electrically connected between the first battery pack and the common bus and configured to disconnect the first battery pack from the common bus in response to current above a second threshold current, wherein the second electrical component has a second disconnection time at the second threshold current that is higher than the first disconnection time.

74. 发明授权

US11464569B2 Systems and methods for pre-operative visualization of a joint 有权
公开(公告)号：US11464569B2
公开(公告)日：2022-10-11
申请号：US16261464
申请日：2019-01-29
申请人： Stryker Corporation
发明人： Floor Lambers , William Kaiser
IPC分类号： A61B34/10 , A61F2/30 , G06F30/00 , A61B17/56
摘要： A method for visualizing at least one region of a joint that deviates from a baseline anatomy includes receiving image data associated with a joint of a subject, generating a three-dimensional model of at least a portion of the joint using the image data, identifying at least one region of the joint that deviates from the baseline anatomy by comparing the three-dimensional model to a baseline model, generating a measurement of a characteristic of the joint at one or more predefined locations using the three-dimensional model and a coordinate system, and generating a three-dimensional rendering of the model that includes a visual indication of the at least one region of the three-dimensional model that deviates from the baseline so that the region is visually indicated according to degree of deviation, and a representation of the measurement of the characteristic of the joint that is positioned according to the predefined locations.

75. 发明授权

US11451507B2 System and method for segmenting users of a one-to-many messaging platform 有权
公开(公告)号：US11451507B2
公开(公告)日：2022-09-20
申请号：US16780890
申请日：2020-02-03
申请人： Community.com, Inc.
发明人： Matthew Peltier , Joshua Rosenheck , Noah Heller , Lars Perkins , Barry Steinglass , Tomas Koci , Alec Rubin
IPC分类号： H04L51/226 , G06F16/908 , G06Q10/10 , H04L51/063 , H04L51/56 , G06N20/00 , G06F16/31 , G06F40/30 , H04W4/06 , H04W4/12 , G06F40/295 , H04L51/046 , G06F40/216 , H04L51/212 , H04L51/216 , H04L51/234
摘要： A system and method for segmenting users of a messaging platform includes receiving a first text message from a client for transmission to a number of users that are registered with the messaging platform. The users are segmented based on one or more user attributes that are defined by static metadata that is generated when each user is registered with the messaging platform, and by dynamic information about user behavior using the messaging platform and/or the one or more second messaging services. The first text message is customized into a set of one or more second text messages according to the segmenting, the customizing providing a context to each of the set of second text messages, the context corresponding to the one or more user attributes.

76. 发明授权

US11450438B2 System and method for outcome tracking and analysis 有权
公开(公告)号：US11450438B2
公开(公告)日：2022-09-20
申请号：US16579496
申请日：2019-09-23
申请人： FOUNDATION MEDICINE, INC.
发明人： Michael Pellini , Gary Palmer , Mary Patricia Lancelotta , Matthew J. Hawryluk , Vincent A. Miller
IPC分类号： G16H70/60 , G16B30/00 , G16H15/00 , G16H10/60 , G16H10/20 , G16H50/20 , G16H20/10
摘要： A system for tracking and analyzing cancer treatment and outcome information includes a user interface (UI) component for allowing selection of an alteration, an affected gene, an affected pathway, a tumor type, and/or a treatment; a processor configured to receive treatment information and outcome information associated with a patient population; organize the treatment information and the outcome information into at least one tuple; and generate outcome summary information; and an analysis component configured to compare a current patient record for a current patient to existing treatment information for the patient population, identify similar patients in the patient population based on information in the current patient record, and filter a grouping of similar patients; the processor is further configured to display, on the UI component, the outcome summary information; enable navigation within the treatment and outcome information; and identify, based on the outcome information, an appropriate treatment for the current patient.

77. 发明授权

US11447822B2 Nucleic acid constructs and methods of use 有权
公开(公告)号：US11447822B2
公开(公告)日：2022-09-20
申请号：US16659428
申请日：2019-10-21
申请人： Prognosys Biosciences, Inc.
发明人： Mark S. Chee
IPC分类号： C12Q1/6869 , C12Q1/6827 , C12Q1/6876 , C12Q1/6806 , C12Q1/6809 , C12Q1/6834 , C12Q1/6874
摘要： The present invention provides oligonucleotide constructs, sets of such oligonucleotide constructs, and methods of using such oligonucleotide constructs to provide validated sequences or sets of validated sequences corresponding to desired ROIs. Such validated ROIs and constructs containing these have a wide variety of uses, including in synthetic biology, quantitative nucleic acid analysis, polymorphism and/or mutation screening, and the like.

78. 发明授权

US11443493B2 Modification of peripheral content in world-locked see-through computer display systems 有权
公开(公告)号：US11443493B2
公开(公告)日：2022-09-13
申请号：US17468494
申请日：2021-09-07
申请人： Mentor Acquisition One, LLC
发明人： John D. Haddick , Ralph F. Osterhout
IPC分类号： G06T19/00 , G02B27/01 , G02B5/30 , G06T19/20 , G06F1/16 , G06F3/01 , G06F5/10 , G09G3/3208 , G09G3/3225 , G09G3/3233 , G02B3/00
摘要： Aspects of the present invention relate to methods and systems for the see-through computer display systems with an extended field of view.

79. 发明授权

US11440969B2 Use of human epididymis protein 4 (HE4) for assessing responsiveness of MUC 16-positive cancer treatment 有权
公开(公告)号：US11440969B2
公开(公告)日：2022-09-13
申请号：US16239663
申请日：2019-01-04
申请人： Genentech, Inc.
发明人： Mark Lackner , Daniel Maslyar , Yulei Wang , Walter Darbonne , Eric Humke
IPC分类号： C07K16/30 , A61K47/68 , G01N33/574 , A61K47/65 , A61P35/00 , A61K31/22 , A61K31/7048 , C07K16/28 , A61K39/00
摘要： The present invention relates to methods and kits or articles of manufacture related thereto that may find use, inter alia, in assessing responsiveness of cancers to MUC16 antagonists by monitoring HE4 expression. In some embodiments, the methods include measuring the level of expression of HE4 in a sample from a subject; comparing the level of expression of HE4 in the sample with the level of expression of HE4 in a sample previously obtained from the subject; and, optionally, administering to the subject a therapeutically effective amount of a MUC16 antagonist.

80. 发明授权

US11432834B2 Shock wave catheter system with energy control 有权
公开(公告)号：US11432834B2
公开(公告)日：2022-09-06
申请号：US16694712
申请日：2019-11-25
申请人： Shockwave Medical, Inc.
发明人： John M. Adams
IPC分类号： A61B17/22
摘要： A system includes a catheter including an elongated carrier, a balloon about the carrier in sealed relation thereto, the balloon being arranged to receive a fluid therein that inflates the balloon, and first and second electrodes within the balloon arranged to carry a voltage there-across including an initial high electrical voltage at an initial low current. The initial high electrical voltage causes an electrical arc to form across the first and second electrodes within the balloon. The electrical arc causes a gas bubble within the liquid, a high current to flow through the first and second electrodes, a decrease in the initial high electrical voltage, and a mechanical shock wave within the balloon. The system further includes a power source that provides the first and second electrodes with a drive voltage that creates the initial high electrical voltage at the initial current and that terminates the drive voltage in response to the decrease in the initial high electrical voltage.

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