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    • 71. 发明授权
    • Method and system for advanced measurements computation and therapy planning from medical data and images using a multi-physics fluid-solid heart model
    • 使用多物理流体 - 固体心脏模型的医学数据和图像进行高级测量计算和治疗计划的方法和系统
    • US09129053B2
    • 2015-09-08
    • US13757517
    • 2013-02-01
    • Tommaso MansiViorel MihalefXudong ZhengBogdan GeorgescuSaikiran RapakaPuneet SharmaAli KamenDorin Comaniciu
    • Tommaso MansiViorel MihalefXudong ZhengBogdan GeorgescuSaikiran RapakaPuneet SharmaAli KamenDorin Comaniciu
    • G06F19/00G06T19/00
    • G06F19/3437G06F19/00G06T19/00G06T2210/41G16H50/50
    • Method and system for computation of advanced heart measurements from medical images and data; and therapy planning using a patient-specific multi-physics fluid-solid heart model is disclosed. A patient-specific anatomical model of the left and right ventricles is generated from medical image patient data. A patient-specific computational heart model is generated based on the patient-specific anatomical model of the left and right ventricles and patient-specific clinical data. The computational model includes biomechanics, electrophysiology and hemodynamics. To generate the patient-specific computational heart model, initial patient-specific parameters of an electrophysiology model, initial patient-specific parameters of a biomechanics model, and initial patient-specific computational fluid dynamics (CFD) boundary conditions are marginally estimated. A coupled fluid-structure interaction (FSI) simulation is performed using the initial patient-specific parameters, and the initial patient-specific parameters are refined based on the coupled FSI simulation. The estimated model parameters then constitute new advanced measurements that can be used for decision making.
    • 用于从医学图像和数据计算先进心脏测量的方法和系统; 并且公开了使用患者特定的多物理流体 - 固体心脏模型的治疗计划。 从医学图像患者数据生成左心室和右心室的患者特异性解剖模型。 基于左心室和右心室的患者特异性解剖模型和患者特异性临床数据生成患者特异性计算心脏模型。 计算模型包括生物力学,电生理学和血液动力学。 为了产生患者特异性计算心脏模型,电生理模型的初始患者特异性参数,生物力学模型的初始患者特异性参数和初始患者特异性计算流体动力学(CFD)边界条件被轻微估计。 使用初始患者特异性参数进行耦合的流体结构相互作用(FSI)模拟,并且基于耦合的FSI模拟来改进初始的患者特异性参数。 估计的模型参数然后构成可用于决策的新的高级测量。
    • 75. 发明申请
    • METHOD FOR ANALYZING PLACEMENT CONTEXT SENSITIVITY OF STANDARD CELLS
    • 分析标准细胞的位置敏感性的方法
    • US20140007029A1
    • 2014-01-02
    • US13536694
    • 2012-06-28
    • Robert E. BoonePuneet SharmaMatthew A. Thompson
    • Robert E. BoonePuneet SharmaMatthew A. Thompson
    • G06F17/50
    • G06F17/5072
    • A disclosed method for evaluating placement context sensitivity in the design of an integrated circuit includes accessing a standard cell library comprising a database of standard cells and determining generating boundary data for each of the standard cells. The boundary data for a standard cell indicates the layout of features located within boundary regions of the standard cell. The method includes merging or consolidating boundary data for any two standard cells if their boundary data is the same to determine a canonical or minimal set of boundary regions. The disclosed method further includes enumerating and evaluating all combinations of pairs of the canonical boundary regions and, responsive to identifying of a proximity-based sensitivity or exception, modifying, notating, or otherwise remediating the applicable one or more standard cells that correspond to the boundary region combination that raised the exception.
    • 用于评估集成电路设计中的放置上下文敏感度的公开的方法包括访问包括标准单元的数据库的标准单元库,并且为每个标准单元确定生成边界数据。 标准单元的边界数据表示位于标准单元的边界区域内的特征的布局。 该方法包括如果边界数据相同以合并或合并任何两个标准单元的边界数据,以确定边界区域的典型或最小集合。 所公开的方法还包括枚举和评估规范边界区域对的所有组合,并且响应于识别基于接近度的灵敏度或异常,修改,表示或以其他方式修复与边界对应的适用的一个或多个标准单元 引起异常的区域组合。