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1. 发明授权

US10162932B2 Method and system for multi-scale anatomical and functional modeling of coronary circulation 有权
公开(公告)号：US10162932B2
公开(公告)日：2018-12-25
申请号：US13672781
申请日：2012-11-09
申请人： Puneet Sharma , Lucian Mihai Itu , Bogdan Georgescu , Viorel Mihalef , Ali Kamen , Dorin Comaniciu
发明人： Puneet Sharma , Lucian Mihai Itu , Bogdan Georgescu , Viorel Mihalef , Ali Kamen , Dorin Comaniciu
IPC分类号： G06F19/12 , G16H50/50 , G06F19/00 , G16H50/30
摘要： A method and system for multi-scale anatomical and functional modeling of coronary circulation is disclosed. A patient-specific anatomical model of coronary arteries and the heart is generated from medical image data of a patient. A multi-scale functional model of coronary circulation is generated based on the patient-specific anatomical model. Blood flow is simulated in at least one stenosis region of at least one coronary artery using the multi-scale function model of coronary circulation. Hemodynamic quantities, such as fractional flow reserve (FFR), are computed to determine a functional assessment of the stenosis, and virtual intervention simulations are performed using the multi-scale function model of coronary circulation for decision support and intervention planning.

2. 发明申请

US20150305706A1 ESTIMATION OF A MECHANICAL PROPERTY OF ANATOMY FROM MEDICAL SCAN DATA 有权
标题翻译：从医学扫描数据估计解剖学的机械性质
公开(公告)号：US20150305706A1
公开(公告)日：2015-10-29
申请号：US14259801
申请日：2014-04-23
申请人： Jingjing Kanik , Puneet Sharma , Tommaso Mansi , Razvan Ionasec , Ali Kamen , Dorin Comaniciu , James S. Duncan
发明人： Jingjing Kanik , Puneet Sharma , Tommaso Mansi , Razvan Ionasec , Ali Kamen , Dorin Comaniciu , James S. Duncan
IPC分类号： A61B8/08
CPC分类号： A61B8/0883 , A61B8/5223 , A61B8/5276
摘要： A mechanical property of anatomy is estimated from a patient in vivo, such as estimating a patient-specific material property of a valve. A morphological model is used to determine anatomy dynamics. A biomechanical model, using the anatomy dynamics, predicts the dynamics, based, at least in part, on one or more material properties. Using an inverse solution based on comparison of dynamics predicted by the biomechanical model and the dynamics determined from the morphological model, values for the material properties are determined.
摘要翻译：从患者身体估计解剖学的机械性质，例如估计瓣膜的患者特异性材料性质。使用形态学模型来确定解剖动力学。使用解剖动力学的生物力学模型预测动力学，至少部分地基于一种或多种材料性质。使用基于生物力学模型预测的动力学与从形态学模型确定的动力学的比较的逆解决方案，确定材料性质的值。

3. 发明授权

US08965084B2 Blood flow computation in vessels with implanted devices 有权
标题翻译：带有植入装置的血管中的血流计算
公开(公告)号：US08965084B2
公开(公告)日：2015-02-24
申请号：US13744857
申请日：2013-01-18
申请人： Viorel Mihalef , Puneet Sharma , Thomas Redel , Ali Kamen
发明人： Viorel Mihalef , Puneet Sharma , Thomas Redel , Ali Kamen
IPC分类号： G06K9/00 , G06K9/36 , G06F19/00 , G06T19/00 , A61B6/03 , A61B6/00
CPC分类号： G16H50/50 , A61B6/032 , A61B6/486 , A61B6/504 , A61B6/5217 , G06T19/00 , G06T2210/41
摘要： A method for modeling blood flow through a flow diverter includes receiving a medical image containing blood vessels. Vessel geometry is extracted from the received medical image. Inlets and outlets are tagged within the extracted vessel geometry. A desired flow diverter is selected. A model of the selected flow diverter is generated within the imaged blood vessel, the model representing the flow diverter as a tube having a porous surface characterized by a viscous resistance and an inertial resistance. A course of blood flow though the flow diverter is predicted based on the generated model, the extracted vessel geometry, and the tagged inlets and outlets.
摘要翻译：通过流转向器对血液流动进行建模的方法包括接收包含血管的医学图像。从接收到的医学图像中提取血管几何。进口和出口在提取的容器几何中被标记。选择所需的分流器。所选流量分流器的模型在成像的血管内产生，该模型表示流量分流器为具有以粘性阻力和惯性阻力为特征的多孔表面的管。基于生成的模型，提取的血管几何形状和标记的入口和出口预测通过流量分流器的血液流动过程。

4. 发明授权

US08898614B2 Integrated circuit device with reduced leakage and method therefor 有权
标题翻译：具有减少泄漏的集成电路装置及其方法
公开(公告)号：US08898614B2
公开(公告)日：2014-11-25
申请号：US12762439
申请日：2010-04-19
申请人： Puneet Sharma , Magdy S. Abadir , Scott P. Warrick
发明人： Puneet Sharma , Magdy S. Abadir , Scott P. Warrick
IPC分类号： G06F17/50 , G06F9/455 , G06F11/22
CPC分类号： G06F17/5072 , G06F2217/12 , G06F2217/78 , Y02P90/265
摘要： A method includes preferentially placing fill regions adjacent to transistors of a particular conductivity type, such as p-channel transistors, for a plurality of standard cell instances of a device design. The method also includes evaluating all transistors of the first conductivity type prior to evaluating any transistors of a second conductivity type. The second conductivity type is opposite the first conductivity type. For each transistor being evaluated, it is determined whether a criterion is me. A fill region is placed within a field isolation region adjacent to the transistor if the criterion is met.
摘要翻译：一种方法包括为设备设计的多个标准单元实例优先地将与特定导电类型的晶体管（例如p沟道晶体管）相邻的填充区域放置。该方法还包括在评估第二导电类型的任何晶体管之前评估第一导电类型的所有晶体管。第二导电类型与第一导电类型相反。对于正在评估的每个晶体管，确定一个标准是否为我。如果满足标准，则将填充区域放置在与晶体管相邻的场隔离区域内。

5. 发明申请

US20140132315A1 INTEGRATED CIRCUIT WITH DEGRADATION MONITORING 有权
标题翻译：集成电路与降解监测
公开(公告)号：US20140132315A1
公开(公告)日：2014-05-15
申请号：US13677800
申请日：2012-11-15
申请人： Puneet Sharma , Matthew A. Thompson , Willard E. Conley
发明人： Puneet Sharma , Matthew A. Thompson , Willard E. Conley
IPC分类号： H03L7/00
CPC分类号： G01R31/3016 , G01R31/2884
摘要： An integrated circuit including a degradation monitoring circuit. The degradation monitoring circuit includes a comparison circuit having a delay element including an input coupled to a data node of a timing path and having an output to provide a delayed signal of a data signal of the data node. The comparison circuit includes a logic comparator that provides a logic comparison between a data signal of the data node and the output of the delay element. The monitoring circuit includes a sampling circuit that provides a sampled signal of the output of the logic comparator that is a sampled with respect to a clock signal of the clock signal line. The monitoring circuit includes a hold circuit that provides a signal indicative of a data signal of the data node transitioning within a predetermined time of an edge transition of a clock signal of the clock signal line.
摘要翻译：一种包括劣化监测电路的集成电路。劣化监视电路包括具有延迟元件的比较电路，该延迟元件包括耦合到定时路径的数据节点的输入，并具有输出以提供数据节点的数据信号的延迟信号。比较电路包括逻辑比较器，其提供数据节点的数据信号和延迟元件的输出之间的逻辑比较。监视电路包括采样电路，该采样电路提供对于时钟信号线的时钟信号采样的逻辑比较器的输出的采样信号。监视电路包括保持电路，该保持电路提供指示在时钟信号线的时钟信号的边沿转换的预定时间内数据节点的数据信号的信号。

6. 发明申请

US20140088935A1 VISCOELASTIC MODELING OF BLOOD VESSELS 审中-公开
标题翻译：血液容器的粘弹性建模
公开(公告)号：US20140088935A1
公开(公告)日：2014-03-27
申请号：US14025039
申请日：2013-09-12
申请人： Lucian Mihai Itu , Puneet Sharma , Ali Kamen , Dorin Comaniciu
发明人： Lucian Mihai Itu , Puneet Sharma , Ali Kamen , Dorin Comaniciu
IPC分类号： G06F19/12
CPC分类号： G06F19/12 , G06F19/00 , G16H50/50
摘要： A method for modeling a blood vessel includes: (a) modeling a first segment of the blood vessel based on medical imaging data acquired from a subject; (b) computing a first modeling parameter at an interior point of the first segment; and (c) computing a second modeling parameter at a boundary point of the first segment using a viscoelastic wall model. Systems for modeling a blood vessel are described
摘要翻译：一种用于对血管建模的方法包括：（a）基于从受试者获得的医学成像数据对血管的第一段进行建模; （b）计算第一段的内部点处的第一建模参数; 和（c）使用粘弹性壁模型在第一段的边界点处计算第二建模参数。描述了对血管建模的系统

7. 发明授权

US08677485B2 Detecting network anomaly 有权
标题翻译：检测网络异常
公开(公告)号：US08677485B2
公开(公告)日：2014-03-18
申请号：US13548638
申请日：2012-07-13
申请人： Puneet Sharma , Sriharsha Gangam , Sonia Fahmy
发明人： Puneet Sharma , Sriharsha Gangam , Sonia Fahmy
IPC分类号： G06F11/00
CPC分类号： G06F21/552
摘要： A method for detecting an anomaly in a network can include combining a number of data-created sketch-sets and requesting a finer sketch-set for an identified sketch-set among the combined number of sketch-sets using an aggregator, and creating the finer sketch-set for the identified sketch-set to detect the anomaly in the network using a monitor.
摘要翻译：用于检测网络中的异常的方法可以包括组合数量创建的草图集并且使用聚合器在组合的草图集合中为识别的草图集请求更精细的素描集，并且创建更细用于使用监视器检测网络异常的识别草图集的草图。

8. 发明申请

US20140020100A1 DETECTING NETWORK ANOMALY 有权
标题翻译：检测网络异常
公开(公告)号：US20140020100A1
公开(公告)日：2014-01-16
申请号：US13548638
申请日：2012-07-13
申请人： Puneet Sharma , Sriharsha Gangam , Sonia Fahmy
发明人： Puneet Sharma , Sriharsha Gangam , Sonia Fahmy
IPC分类号： G06F21/00
CPC分类号： G06F21/552
摘要： A method for detecting an anomaly in a network can include combining a number of data-created sketch-sets and requesting a finer sketch-set for an identified sketch-set among the combined number of sketch-sets using an aggregator, and creating the finer sketch-set for the identified sketch-set to detect the anomaly in the network using a monitor.
摘要翻译：用于检测网络中的异常的方法可以包括组合数量创建的草图集并且使用聚合器在组合的草图集合中为识别的草图集请求更精细的素描集，并且创建更细用于使用监视器检测网络中的异常的识别草图集的草图。

9. 发明申请

US20130287033A1 ROUTING DATA PACKETS ON A NETWORK 有权
标题翻译：在网络上路由数据包
公开(公告)号：US20130287033A1
公开(公告)日：2013-10-31
申请号：US13460132
申请日：2012-04-30
申请人： Puneet Sharma , Tianxiong Ji , Zhikui Wang
发明人： Puneet Sharma , Tianxiong Ji , Zhikui Wang
IPC分类号： H04L12/56 , H04L12/28
CPC分类号： H04L45/54
摘要： A plurality of data flows can be routed from a first node of the network to one or more other nodes of the network. A destination of a data packet for each data flow is determined. When the destination node of the data packet of that data flow is not adjacent to the first node, a probabilistic determination is made for a next hop of data packets of that data flow. When the destination node of the data packet of that data flow is adjacent to the first node, a priority designation is made for the next hop of data packets of that data flow as being the destination node. The next hop for data packets of the data flow is determined based on either the probabilistic determination or the priority designation.
摘要翻译：多个数据流可以从网络的第一节点路由到网络的一个或多个其他节点。确定每个数据流的数据包的目的地。当该数据流的数据分组的目的地节点不与第一节点相邻时，对该数据流的数据分组的下一跳进行概率确定。当该数据流的数据分组的目的地节点与第一节点相邻时，对该数据流的数据分组的下一跳作为目的地节点进行优先级指定。基于概率确定或优先级指定来确定数据流的数据分组的下一跳。

10. 发明授权

US08565218B2 Flow path discovery in network to guarantee multiple metric QoS constraints 有权
标题翻译：网络中的流路发现，以保证多个度量QoS约束
公开(公告)号：US08565218B2
公开(公告)日：2013-10-22
申请号：US12263429
申请日：2008-10-31
申请人： Puneet Sharma , Amit Mondal , Sujata Banerjee
发明人： Puneet Sharma , Amit Mondal , Sujata Banerjee
IPC分类号： H04L12/28 , G06F15/173
CPC分类号： H04L45/302 , H04L45/02 , H04L45/124 , H04L45/38 , H04L45/64 , H04L45/70
摘要： Route discovery for an end-to-end path in a network is performed for a flow. A path is attempted to be discovered that satisfies QoS constraints for multiple metrics for the flow. The route discovery includes determining whether a path request for a path satisfying the QoS constraints is feasible, infeasible or undecideable based on information in a local QoS table. If the path request is determined to be undecideable, route discovery is performed with neighbors.
摘要翻译：针对流程执行网络中端到端路径的路由发现。尝试发现一个满足流量多个度量的QoS约束的路径。该路由发现包括确定针对满足QoS约束的路径的路径请求是否可行，基于本地QoS表中的信息是不可行或不可切换的。如果路径请求被确定为不可取消，则路由发现与邻居一起执行。

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