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71. 发明授权

US09488574B2 Device for imaging the interior of an optically turbid medium and receptacle unit for such a device 有权
标题翻译：用于对用于这种装置的光学混浊介质和插座单元的内部进行成像的装置
公开(公告)号：US09488574B2
公开(公告)日：2016-11-08
申请号：US12682939
申请日：2008-10-13
申请人： Thomas Koehler , Tim Nielsen , Bernhard Brendel , Andy Ziegler , Ronny Ziegler , Levinus Pieter Bakker , Martinus Bernardus Van Der Mark
发明人： Thomas Koehler , Tim Nielsen , Bernhard Brendel , Andy Ziegler , Ronny Ziegler , Levinus Pieter Bakker , Martinus Bernardus Van Der Mark
IPC分类号： G01N21/47 , A61B5/00 , G01N21/17
CPC分类号： G01N21/4795 , A61B5/0073 , A61B5/0091 , A61B5/4312 , A61B2562/146 , G01N2021/1787 , G01N2201/0826 , G01N2201/0833
摘要： A device (1) for imaging the interior of an optically turbid medium is provided. The device comprises a receptacle (3; 103) structured to accommodate an optically turbid medium for examination and an optically matching medium filling a space between an inner surface (6; 106) of the receptacle (3; 103) and the optically turbid medium. The device comprises at least one light source generating light to be coupled into the receptacle (3; 103) and at least one detector for detecting light emanating from the receptacle (3; 103). A coupling surface (10; 110) optically coupled to the inner surface (6; 106) of the receptacle and a coupling member (11; 111) optically coupled to the light source and the detector are provided. The coupling surface (10; 110) and the coupling member (11; 111) are movable to a plurality of different positions relative to each other and structured to establish an optical connection from the light source to the inner surface (6; 106) of the receptacle and from the inner surface (6; 106) of the receptacle to the at least one detector in the plurality of different positions.
摘要翻译：提供了用于对光学混浊介质的内部成像的装置（1）。该装置包括构造成容纳用于检查的光学混浊介质的容器（3; 103）和填充容器（3; 103）的内表面（6; 106）与光学混浊介质之间的空间的光学匹配介质。所述装置包括至少一个光源，其产生要耦合到所述插座（3; 103）中的光和至少一个用于检测从所述插座（3; 103）发出的光的检测器。光耦合到容器的内表面（6; 106）的耦合表面（10; 110）和光学耦合到光源和检测器的耦合构件（11; 111）。联接表面（10; 110）和联接构件（11; 111）可以相对于彼此移动到多个不同的位置，并被构造成建立从光源到内表面（6; 106）的光学连接所述容器和所述容器的内表面（6; 106）到所述多个不同位置中的所述至少一个检测器。

72. 发明授权

US09412184B2 Regularized phase retrieval in differential phase-contrast imaging 有权
标题翻译：差分相位成像中的正则化相位检索
公开(公告)号：US09412184B2
公开(公告)日：2016-08-09
申请号：US13820179
申请日：2011-09-01
申请人： Thomas Koehler , Ewald Roessl
发明人： Thomas Koehler , Ewald Roessl
IPC分类号： G06K9/00 , G06T11/00 , A61B6/00
CPC分类号： G06T11/003 , A61B6/484 , G06T11/005 , G06T11/006
摘要： The present invention relates to differential phase-contrast imaging of an object (108). When reconstructing image information from differential phase-contrast image data, streak- like artefacts (502) may occur. The artefacts (502) may substantially reduce legibility of reconstructed image data. Accordingly, it may be beneficial for removing or at least suppressing said artefacts (502). Thus, a method (400) for regularized phase retrieval in phase-contrast imaging is provided comprising receiving (402) differential phase-contrast image data of an object (108); generating (404) reconstructed image data of an object (108) and presenting (406) reconstructed image data of the object (108). The differential phase-contrast image and the reconstructed image data comprise a two-dimensional data structure having a first dimension and a second dimension. Generating reconstructed image data comprises integration of image data in one of the first dimension and the second dimension of the data structure. A gradient operator is determined in the other one of the first dimension and second dimension of the data structure and the data structure is employed for reconstructing image data resulting in a reduction of artefacts (500) within the reconstructed image data.
摘要翻译：本发明涉及物体（108）的差分相位对比成像。当从差分相位差图像数据重建图像信息时，可能会出现条纹状伪像（502）。人造物（502）可以大大降低重构图像数据的可读性。因此，去除或至少抑制所述伪影（502）可能是有益的。因此，提供了一种用于相位对比成像中的正则化相位检索的方法（400），包括：接收（402）对象（108）的差分相位对比图像数据; 生成（404）对象（108）的重建图像数据并呈现（406）对象（108）的重建图像数据。差分相位对比图像和重构图像数据包括具有第一维度和第二维度的二维数据结构。生成重构图像数据包括将图像数据集成在数据结构的第一维度和第二维度之一中。在数据结构的第一维度和第二维度中的另一个维度中确定梯度算子，并且采用数据结构来重建图像数据，导致重构图像数据内的伪像（500）的减少。

73. 发明授权

US09348067B2 Tilted gratings and method for production of tilted gratings 有权
标题翻译：倾斜光栅和倾斜光栅的生产方法
公开(公告)号：US09348067B2
公开(公告)日：2016-05-24
申请号：US13319196
申请日：2010-06-09
申请人： Gereon Vogtmeier , Klaus Juergen Engel , Thomas Koehler , Ewald Roessl
发明人： Gereon Vogtmeier , Klaus Juergen Engel , Thomas Koehler , Ewald Roessl
IPC分类号： G21K1/00 , G02B5/18 , A61B6/00
CPC分类号： G02B5/1857 , A61B6/484 , G21K2201/06 , G21K2207/005
摘要： The present invention relates to phase-contrast imaging which visualizes the phase information of coherent radiation passing a scanned object. Focused gratings are used which reduce the creation of trapezoid profile in a projection with a particular angle to the optical axis. A laser supported method is used in combination with a dedicating etching process for creating such focused grating structures.
摘要翻译：本发明涉及相位成像，其可视化通过扫描对象的相干辐射的相位信息。使用聚焦光栅，其减小了与光轴具有特定角度的投影中的梯形轮廓的产生。激光支持的方法与用于产生这种聚焦光栅结构的专用蚀刻工艺组合使用。

74. 发明授权

US09299169B2 Iterative reconstruction algorithm with a constant variance based weighting factor 有权
标题翻译：具有恒定方差加权因子的迭代重建算法
公开(公告)号：US09299169B2
公开(公告)日：2016-03-29
申请号：US13990450
申请日：2011-11-25
申请人： Bernhard Johannes Brendel , Thomas Koehler , Holger Schmitt , Rolf Dieter Bippus , Roland Proksa
发明人： Bernhard Johannes Brendel , Thomas Koehler , Holger Schmitt , Rolf Dieter Bippus , Roland Proksa
IPC分类号： G06T11/00
CPC分类号： G06T11/003 , G06T11/006 , G06T2211/424
摘要： A method includes reconstructing measured projection data using an iterative statistical reconstruction algorithm that reduces image artifact caused by differences in variances in projections of the measured projection data used to update a voxel of the image for one or more voxels of the image. A reconstructor includes a processor that reconstructs measured projection data using an iterative statistical reconstruction algorithm that reduces or mitigates image artifact caused by differences in variances in projections used to update a voxel of the image for one or more voxels of the image. A computer readable storage medium encoded with computer executable instructions, which, when executed by a processor of a computer, cause the processor to: reduce image artifact caused by differences in variances in projections used to update a voxel of an image for one or more voxels of the image using an iterative statistical reconstruction algorithm.
摘要翻译：一种方法包括使用迭代统计重建算法来重建测量的投影数据，所述迭代统计重构算法减少由用于更新图像的一个或多个体素的图像的体素的测量投影数据的投影方差的差异引起的图像伪像。重构器包括使用迭代统计重建算法来重建测量的投影数据的处理器，其减少或减轻由用于更新图像的一个或多个体素的图像的体素的投影方差的差异引起的图像伪像。一种用计算机可执行指令编码的计算机可读存储介质，其在由计算机的处理器执行时使处理器能够：减少由用于更新一个或多个体素的图像的体素的投影差异的差异引起的图像伪像的图像使用迭代统计重建算法。

75. 发明授权

US09044187B2 Post-patient dynamic filter for computed tomography (CT) 有权
标题翻译：用于计算机断层扫描（CT）的患者后动态滤波器
公开(公告)号：US09044187B2
公开(公告)日：2015-06-02
申请号：US13992302
申请日：2011-12-02
申请人： Thomas Koehler , Holger Schmitt , Roland Proksa
发明人： Thomas Koehler , Holger Schmitt , Roland Proksa
IPC分类号： A61B6/00 , A61B6/03 , G21K1/10 , A61B6/06
CPC分类号： A61B6/4035 , A61B6/032 , A61B6/06 , A61B6/4241 , A61B6/4291 , A61B6/488 , A61B6/544 , G21K1/10
摘要： An imaging system includes a radiation source (310) configured to rotate around an examination region about a z-axis and having a focal spot that emits a radiation beam that traverses the examination region. The system further includes a radiation sensitive detector array (314) with a plurality of detector pixels that detects radiation traversing the examination region and generates projection data indicative of the detected radiation. The system further includes a dynamic post-patient filter (316) including one or more filter segments (402, 802, 902, 1004, 1102). The filter is configured to selectively and dynamically move in front of the detector array between the detector array and the examination region and into and out of a path of the radiation beam illuminating the detector pixels during scanning an object or subject based on a shape of the object or subject, thereby filtering unattenuated radiation and radiation traversing a periphery of the object or subject.
摘要翻译：成像系统包括被配置为围绕z轴围绕检查区域旋转并具有发射穿过检查区域的辐射束的焦点的辐射源（310）。该系统还包括具有多个检测器像素的辐射敏感检测器阵列（314），其检测穿过检查区域的辐射，并产生指示检测到的辐射的投影数据。该系统还包括动态的患者后过滤器（316），其包括一个或多个过滤器段（402,802,902,1004,1102）。滤波器被配置为在检测器阵列和检查区域之间选择性地和动态地在检测器阵列之前移动，并且在扫描对象或被摄体期间，在扫描对象或被摄体期间进入和离开照射检测器像素的辐射束的路径，物体或物体，从而过滤未被衰减的辐射和穿过物体或物体的周边的辐射。

76. 发明授权

US09002090B2 Forward projection apparatus 有权
标题翻译：前投投影仪
公开(公告)号：US09002090B2
公开(公告)日：2015-04-07
申请号：US13988349
申请日：2011-11-16
申请人： Thomas Koehler , Bernhard Johannes Brendel , Holger Schmitt , Rolf Dieter Bippus
发明人： Thomas Koehler , Bernhard Johannes Brendel , Holger Schmitt , Rolf Dieter Bippus
IPC分类号： G06K9/00 , G06T11/00
CPC分类号： G06T11/005 , G06T11/008 , G06T2211/424
摘要： The invention relates to a forward projection apparatus for performing a forward projection through an image (22), wherein at least one of a number of rays (20, 21) for performing the forward projection, a ray spacing between the rays and a kernel width of an interpolation kernel for calculating interpolated values located on the rays is varied depending on the ray width relative to an effective image element spacing between image elements (24) of the image. This allows reducing artifacts in simulated projection data and, thus, in an image, which is iteratively reconstructed by using the simulated projection data. For example, if the number of provided rays and/or the ray spacing between the provided rays is varied, aliasing artifacts can be reduced. Moreover, if the ray spacing between the provided rays and/or the kernel width of the interpolation kernel is varied, artifacts caused by varying effective kernel widths may be reduced.
摘要翻译：本发明涉及一种用于通过图像（22）进行向前投影的前投影装置，其中，用于执行向前投影的多个光线（20,21）中的至少一个，光线之间的光线间隔和核宽度用于计算位于光线上的内插值的插值内核根据相对于图像的图像元素（24）之间的有效图像元素间隔的光线宽度而变化。这允许减少模拟投影数据中的伪影，并因此减少通过使用模拟投影数据迭代重建的图像。例如，如果提供的光线的数量和/或所提供的光线之间的光线间隔变化，则可以减少混叠伪影。此外，如果所提供的光线之间的光线间距和/或内插核的内核宽度发生变化，则可能会降低由变化的有效内核宽度引起的伪影。

77. 发明授权

US08873823B2 Motion compensation with tissue density retention 有权
标题翻译：运动补偿与组织密度保留
公开(公告)号：US08873823B2
公开(公告)日：2014-10-28
申请号：US13510153
申请日：2010-11-18
申请人： Thomas Koehler , Tobias Klinder , Sven Kabus
发明人： Thomas Koehler , Tobias Klinder , Sven Kabus
IPC分类号： G06K9/00 , G06T11/00
CPC分类号： G06T11/008 , G06T2211/412
摘要： A method includes reconstructing the projection data based on a reconstruction algorithm that compensates for both motion and tissue density changes of the moving organ across different motion phases, thereby generating motion and density compensated image data. A data compensator includes a reconstructor that reconstructs motion compensated image data based on an reconstruction algorithm that compensates for tissue density changes in a moving object.
摘要翻译：一种方法包括基于补偿运动器官在不同运动相位上的运动和组织密度变化的重建算法重建投影数据，从而产生运动和密度补偿图像数据。数据补偿器包括重建器，其基于补偿移动物体中的组织密度变化的重建算法重建运动补偿图像数据。

78. 发明申请

US20140295287A1 LITHIUM ION-CONDUCTING GARNET-LIKE COMPOUNDS 有权
标题翻译：锂离子导电GARNET-LIKE化合物
公开(公告)号：US20140295287A1
公开(公告)日：2014-10-02
申请号：US14233940
申请日：2012-05-21
申请人： Ulrich Eisele , Thomas Koehler , Stefan Hinderberger , Boris Kozinsky , Alan Logeat
发明人： Ulrich Eisele , Thomas Koehler , Stefan Hinderberger , Boris Kozinsky , Alan Logeat
IPC分类号： H01M10/0562 , H01M10/052
CPC分类号： H01M10/0562 , C01G25/006 , C01G33/006 , C01G35/006 , C04B35/481 , C04B35/486 , C04B35/495 , C04B35/62675 , C04B2235/3203 , C04B2235/3213 , C04B2235/322 , C04B2235/3227 , C04B2235/3244 , C04B2235/3251 , C04B2235/3418 , C04B2235/6562 , C04B2235/764 , H01M10/052 , H01M2300/0071
摘要： A lithium ion-conducting compound, having a garnet-like crystal structure, and having the general formula: Lin[A(3-a′-a″)A′(a′)A″(a″)][B(2-b′-b″)B′(b′)B″(b″)][C′(c′)C″(c″)]O12, where A, A′, A″ stand for a dodecahedral position of the crystal structure, where A stands for La, Y, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm and/or Yb, A′ stands for Ca, Sr and/or Ba, A″ stands for Na and/or K, 0
摘要翻译：具有石榴石状晶体结构的锂离子导电化合物，具有以下通式：Lin [A（3-a'-a“）A'（a'）A”（a“）] [B（2 B'（b'）B“（b”）] [C'（c'）C“（c”）] O 12，其中A，A'，A“代表十二面体位置晶体结构，其中A代表La，Y，Pr，Nd，Sm，Eu，Gd，Tb，Dy，Ho，Er，Tm和/或Yb，A'代表Ca，Sr和/或Ba，A“ 代表Na和/或K，0

79. 发明申请

US20130315373A1 DIFFERENTIAL PHASE-CONTRAST IMAGING WITH FOCUSSING DEFLECTION STRUCTURE PLATES 审中-公开
标题翻译：具有聚焦偏转结构板的差分相位成像
公开(公告)号：US20130315373A1
公开(公告)日：2013-11-28
申请号：US13982781
申请日：2012-01-30
申请人： Ewald Rössl , Thomas Koehler
发明人： Ewald Rössl , Thomas Koehler
IPC分类号： G21K1/06 , G01N23/04
摘要： The present invention relates to X-ray differential phase-contrast imaging, in particular to a deflection device for X-ray differential phase-contrast imaging. In order to provide differential phase-contrast imaging with improved dose efficiency, a deflection device (28) for X-ray differential phase-contrast imaging is provided, comprising a deflection structure (41) with a first plurality (44) of first areas (46), and a second plurality (48) of second areas (50). The first areas are provided to change the phase and/or amplitude of an X-ray radiation; and wherein the second areas are X-ray transparent. The first and second areas are arranged periodically such that, in the cross section, the deflection structure is provided with a profile arranged such that the second areas are provided in form of groove-like recesses (54) formed between first areas provided as projections (56). The adjacent projections form respective side surfaces (58) partly enclosing the respective recess arranged in between. The side surfaces of each recess have a varying distance (60) across the depth (62) of the recess.
摘要翻译：本发明涉及X射线差分相位对比成像，特别涉及用于X射线差分相位对比成像的偏转装置。为了提供具有改进的剂量效率的差分相位对比成像，提供了一种用于X射线差分相位对比成像的偏转装置（28），包括具有第一多个第一区域（44）的偏转结构（41） 46）和第二多个（48）第二区域（50）。提供第一区域以改变X射线辐射的相位和/或幅度; 并且其中所述第二区域是X射线透明的。第一和第二区域周期性地布置，使得在横截面中，偏转结构设置有轮廓，轮廓布置成使得第二区域以形成在作为突起的第一区域之间形成的凹槽状凹部（54） 56）。相邻的突起形成部分地围绕设置在其间的相应凹部的相应侧表面（58）。每个凹部的侧表面具有穿过凹部的深度（62）的变化的距离（60）。

80. 发明授权

US08594321B2 Apparatus and method for operating a symmetric cipher engine in cipher-block chaining mode 失效
标题翻译：用于在密码块链接模式下操作对称密码引擎的装置和方法
公开(公告)号：US08594321B2
公开(公告)日：2013-11-26
申请号：US12257439
申请日：2008-10-24
申请人： Ulrich Mayer , Thomas Koehler , Bernd Nerz
发明人： Ulrich Mayer , Thomas Koehler , Bernd Nerz
IPC分类号： H04K1/00
CPC分类号： H04L9/0637 , H04L2209/12
摘要： An apparatus is disclosed for operating a symmetric cipher engine (SCE) in cipher-block chaining (CBC) mode. The apparatus includes a crypto operation hardware including the SCE and an XOR stage, an apparatus for storing a chaining value including a state register of the SCE, an input latch supplying the crypto operation hardware with data, and an output latch. The data may be reordered for decipher operation. Furthermore, a method is disclosed for operating a SCE in CBC mode, wherein the method involves a crypto operation hardware that includes the SCE and an XOR stage supplied with data. The method also may include using a state register of the SCE to apply a chaining value. The method further may comprise reordering data supplied to the crypto operation hardware for decipher operation.
摘要翻译：公开了一种用于在密码块链接（CBC）模式下操作对称密码引擎（SCE）的装置。该装置包括包括SCE和XOR级的加密操作硬件，用于存储包括SCE的状态寄存器的链接值，向密码操作硬件提供数据的输入锁存器和输出锁存器的装置。数据可以被重新排序用于解密操作。此外，公开了一种用于以CBC模式操作SCE的方法，其中该方法涉及包括SCE和提供有数据的XOR级的密码操作硬件。该方法还可以包括使用SCE的状态寄存器来应用链接值。该方法还可以包括将提供给密码操作硬件的数据重新排序以进行解密操作。

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