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81. 发明授权

US08759065B2 Protein and DNA sequence encoding a cold adapted subtilisin-like activity 有权
标题翻译：编码冷适应枯草杆菌蛋白酶样活性的蛋白质和DNA序列
公开(公告)号：US08759065B2
公开(公告)日：2014-06-24
申请号：US12672226
申请日：2008-08-06
申请人： Juan A. Asenjo , Barbara A. Andrews , Juan Pablo Acevedo , Fernando Reyes , Luis O. Burzio
发明人： Juan A. Asenjo , Barbara A. Andrews , Juan Pablo Acevedo , Fernando Reyes , Luis O. Burzio
IPC分类号： C12N9/48 , C12N15/63 , C07H21/04 , C12N1/20
CPC分类号： C12N9/52
摘要： Nucleic acid and corresponding amino acid sequences of a cold adapted subtilisin-like activity protein, insolated from antarctic marine origin, preferably from an Antarctic bacteria (Polaribacter sp) that can be used in a variety of industrial contexts and commercial purposes including laundry detergents, food processing, leather processing and skin care products. Nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the cold adapted subtilisin-like protein are also described.
摘要翻译：来自南极海洋来源的冷适应的枯草杆菌蛋白酶样活性蛋白质的核酸和相应的氨基酸序列，优选来自可用于各种工业环境和商业目的的南极细菌（Polaribacter sp），包括洗衣洗涤剂，食品加工，皮革加工和护肤品。还描述了包含核酸序列的核酸构建体，载体和宿主细胞以及用于产生和使用冷适应的枯草杆菌蛋白酶样蛋白质的方法。

82. 发明授权

US08750654B2 Photonic integrated circuit having a waveguide-grating coupler 有权
标题翻译：具有波导光栅耦合器的光子集成电路
公开(公告)号：US08750654B2
公开(公告)日：2014-06-10
申请号：US13919396
申请日：2013-06-17
申请人： Alcatel-Lucent USA Inc.
发明人： Nicolas Dupuis , Christopher R. Doerr
IPC分类号： G02B6/12 , G02B6/125 , G02B6/30 , G02B6/136 , B82Y20/00 , B29D11/00 , G02B6/10 , G02B6/124 , G02B6/293
CPC分类号： G02B6/10 , B29D11/00663 , B82Y20/00 , G02B6/12002 , G02B6/124 , G02B6/125 , G02B6/136 , G02B6/29332 , G02B6/305 , G11B5/314 , G11B2005/0021
摘要： A photonic integrated circuit (PIC) having a waveguide-grating coupler with two evanescently coupled waveguides. The first waveguide is fabricated using materials suitable for manufacturing active optical elements in the PIC. The second waveguide is fabricated using materials capable of providing a relatively high index-of-refraction contrast for the constituent waveguide grating. The waveguide-grating coupler is compatible with the III-V semiconductor technology while being relatively easy to fabricate on an industrial scale.
摘要翻译：一种具有波导 - 光栅耦合器的光子集成电路（PIC），具有两个渐逝耦合波导。使用适合制造PIC中的有源光学元件的材料制造第一个波导。使用能够为组成波导光栅提供相对较高的折射率对比度的材料来制造第二波导。波导光栅耦合器与III-V半导体技术相兼容，同时在工业规模上相对容易制造。

83. 发明授权

US08722427B2 Determination of dissociation constants using piezoelectric microcantilevers 失效
标题翻译：使用压电微悬臂梁测定解离常数
公开(公告)号：US08722427B2
公开(公告)日：2014-05-13
申请号：US12900160
申请日：2010-10-07
申请人： Wan Y. Shih , Joseph Capobianco , Wei-Heng Shih
发明人： Wan Y. Shih , Joseph Capobianco , Wei-Heng Shih
IPC分类号： G01N33/551
CPC分类号： G01N33/54373
摘要： A method for determining the dissociation constant (Kd) by plotting resonance frequency shift as a function of time for various target analyte concentrations. From this graph, the fraction of saturation, i.e. equilibrium fraction of bound binding sites out of all available binding sites on the sensor surface may be estimated by taking the ratio of the equilibrium resonance frequency shift at a selected concentration to the equilibrium frequency shift of the sensor. The dissociation constant is the inverse slope of the line produced by graphing the fraction of saturation as a function of concentration. This method is particularly useful for the study of protein-protein and protein-mRNA interactions.
摘要翻译：通过绘制各种目标分析物浓度作为时间的函数的共振频移来确定解离常数（Kd）的方法。从该图中可以通过将选定浓度下的平衡共振频移与平衡频移的比值来估计饱和度的分数，即在传感器表面上所有可用结合位点之间的结合结合位点的平衡分数传感器。解离常数是通过绘制作为浓度的函数的饱和分数而产生的线的反斜率。这种方法对于研究蛋白质和蛋白质 - mRNA相互作用特别有用。

84. 发明授权

US08713495B2 Accelerator for a read-channel design and simulation tool 有权
标题翻译：加速器，用于读通道设计和仿真工具
公开(公告)号：US08713495B2
公开(公告)日：2014-04-29
申请号：US13780222
申请日：2013-02-28
申请人： LSI Corporation
发明人： Pavel Aleksandrovich Aliseychik , Aleksey Alexandrovich Letunovskiy , Alexander Alexandrovich Petyushko , Denis Vladimirovich Parkhomenko , Alexander Borisovich Kholodenko
IPC分类号： G06F17/50
CPC分类号： G06F17/5022 , G06F17/5045 , G06F17/505
摘要： A computer-aided design method for developing, simulating, and testing a read-channel architecture to be implemented in a VLSI circuit. The method uses a coset operating mode and nonzero-syndrome-based decoding to accelerate the simulation of the read-channel's error-rate characteristics corresponding to different parity-check matrices employed in the read-channel's turbo-decoder, such as a low-density parity-check decoder. The acceleration is achieved through recycling some previously generated log-likelihood-ratio values, which enables the method to sometimes bypass certain time-consuming processing steps therein.
摘要翻译：一种用于开发，仿真和测试在VLSI电路中实现的读通道架构的计算机辅助设计方法。该方法使用陪集操作模式和基于非零校正的解码来加速对于在读通道的turbo解码器中采用的不同奇偶校验矩阵对应的读通道的误码率特性的模拟，例如低密度奇偶校验解码器。通过再循环一些先前产生的对数似然比值来实现加速，这使得该方法有时可以绕过其中一些耗时的处理步骤。

85. 发明授权

US08708303B2 Hanging device 有权
标题翻译：挂机
公开(公告)号：US08708303B2
公开(公告)日：2014-04-29
申请号：US10904729
申请日：2004-11-24
申请人： Herbert Mark Bigelow
发明人： Herbert Mark Bigelow
IPC分类号： A47G1/16
CPC分类号： A47G1/162
摘要： A device for hanging an object on a vertical structure, such as a framed picture or painting on a wall. The device comprises a body having a planar portion that lies in a plane defining a first direction and a second direction transverse to the first direction. A plurality of openings are present in the planar portion, and the openings are arranged in a two-dimensional pattern so that each opening is offset in the first and second directions from at least a second of the openings. The device further includes a feature for securing the body to the object.
摘要翻译：用于将物体悬挂在垂直结构上的装置，例如框架图片或在墙上绘画。该装置包括具有平面部分的主体，该平面部分位于限定第一方向的平面和横向于第一方向的第二方向。在平面部分中存在多个开口，并且开口以二维图案布置，使得每个开口在至少第二个开口处沿第一和第二方向偏移。该装置还包括用于将身体固定到物体的特征。

86. 发明授权

US08695227B2 Work piece cutting guide 失效
标题翻译：工件切割指南
公开(公告)号：US08695227B2
公开(公告)日：2014-04-15
申请号：US13365552
申请日：2012-02-03
申请人： Gary Sherman
发明人： Gary Sherman
IPC分类号： G01B3/10
CPC分类号： G01B3/1084 , B25H1/0078 , G01B3/1005 , G01B2003/1015 , G01B2003/1079 , G01B2003/1089
摘要： In one embodiment, a cutting guide has a base with a flat lower surface for resting the cutting guide on an upper surface of a work piece. Extending down from the front of the base is an abutment member that aligns the base with a front surface of the work piece. A fence is installed on the upper surface of one side of the base to guide a cutting instrument across the work piece. A kick-up preventer extends from the top of the fence away from the base to prevent the cutting instrument from kicking-up during operation. On the other side of the base, a tape measure is mounted on the upper surface such that the tape extends away from the fence, and a measurement-securing assembly is mounted in front of the tape measure to secure the tape measure at a desired measurement.
摘要翻译：在一个实施例中，切割引导件具有用于将切割引导件放置在工件的上表面上的平坦下表面的基部。从基座的前部向下延伸的是将基座与工件的前表面对准的抵接构件。围栏安装在基座一侧的上表面上，以引导切割工具穿过工件。防撬装置从护栏的顶部远离底座延伸，以防止切割仪器在操作过程中进行踢球。在基座的另一侧，在上表面上安装卷尺，使得带从栅栏延伸，并且测量固定组件安装在卷尺的前面，以将卷尺固定在期望的测量。

87. 发明授权

US08683299B2 Adjusting input samples in turbo equalization schemes to break trapping sets 有权
标题翻译：调整Turbo均衡方案中的输入样本以打破陷阱集
公开(公告)号：US08683299B2
公开(公告)日：2014-03-25
申请号：US12540035
申请日：2009-08-12
申请人： Kiran Gunnam , Shaohua Yang , Changyou Xu
发明人： Kiran Gunnam , Shaohua Yang , Changyou Xu
IPC分类号： G06F11/10
CPC分类号： H03M13/1111 , H03M13/09 , H03M13/1142 , H03M13/3707 , H03M13/3738 , H03M13/3753 , H03M13/451
摘要： In one embodiment, a turbo equalizer has a channel detector that receives equalized samples and generates channel soft-output values. An LDPC decoder attempts to decode the channel soft-output values to recover an LDPC-encoded codeword. If the decoder converges on a trapping set, then an adjustment block selects one or more of the equalized samples based on one or more specified conditions and adjusts the selected equalized samples. Selection may be performed by identifying the locations of unsatisfied check nodes of the last local decoder iteration and selecting the equalized samples that correspond to bit nodes of the LDPC-encoded codeword that are connected to the unsatisfied check nodes. Adjustment of the equalized samples may be performed using any combination of scaling, offsetting, and saturation. Channel detection is then performed using the adjusted equalized samples to generate an updated set of channel soft-output values, which are subsequently decoded by the decoder.
摘要翻译：在一个实施例中，turbo均衡器具有信道检测器，其接收均衡的样本并产生信道软输出值。 LDPC解码器尝试对通道软输出值进行解码以恢复LDPC编码的码字。如果解码器收敛于捕获集合，则调整块基于一个或多个指定条件选择一个或多个均衡样本，并调整所选择的均衡样本。可以通过识别最后的本地解码器迭代的不满足的校验节点的位置并选择与连接到不满足的校验节点的LDPC编码码字的比特节点相对应的均衡样本来执行选择。可以使用缩放，偏移和饱和度的任何组合来执行均衡样本的调整。然后使用经调整的均衡采样来执行信道检测，以产生随后由解码器解码的更新的信道软输出值集合。

88. 发明授权

US08679814B2 Protein and DNA sequence encoding a cold adapted xylanase 有权
标题翻译：编码冷适应木聚糖酶的蛋白质和DNA序列
公开(公告)号：US08679814B2
公开(公告)日：2014-03-25
申请号：US13148227
申请日：2010-02-02
申请人： Juan A. Asenjo , Barbara A. Andrews , Juan Pablo Acevedo , Loreto Parra , Luis O. Burzio
发明人： Juan A. Asenjo , Barbara A. Andrews , Juan Pablo Acevedo , Loreto Parra , Luis O. Burzio
IPC分类号： C12N9/24 , C12N1/00 , C12N1/20 , C12N15/00 , C07H21/04
CPC分类号： C12N9/2434 , C12Y302/01008
摘要： A method of preparing a cold adapted xylanase by use of recombinant DNA techniques. A nucleic acid and corresponding amino acid sequences of a cold adapted xylanase, isolated from antarctic marine origin, preferably from an Antarctic bacteria (Psychrobacter sp.) are provided. These can be used in a variety of industrial contexts and for a variety of commercial purposes including more complete hydrolysis of lignocellulosic biomass into simple sugars that can then be fermented to products, such as liquid fuels and chemical feedstocks. The enzymes are also useful in the production methods of other industries, such as the animal feed, baking, and paper industries. Nucleic acids, corresponding amino acid sequences, constructs, expression vectors or integration vectors containing the DNA molecule, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides for producing and using the Psychrobacter-derived cold adapted family GH10 xylanase-like protein are also described.
摘要翻译：使用重组DNA技术制备冷适应木聚糖酶的方法。提供了从南极海洋来源分离的冷适应木聚糖酶的核酸和相应的氨基酸序列，优选来自南极细菌（Psychrobacter sp。）。这些可用于各种工业环境和各种商业目的，包括将木质纤维素生物质更完全水解成简单的糖，然后将其发酵成产物，例如液体燃料和化学原料。酶也可用于其他行业的生产方法，如动物饲料，烘焙和造纸工业。含有DNA分子的核酸，相应的氨基酸序列，构建体，表达载体或整合载体，以及包含多核苷酸的宿主细胞以及用于产生和使用多肽用于产生和使用来源于精神分裂杆菌的冷适应家族GH10木聚糖酶 - 也描述了类似的蛋白质。

89. 发明授权

US08667709B2 Shoe sole orthotic structures and computer controlled compartments 有权
标题翻译：鞋底矫形结构和电脑控制隔间
公开(公告)号：US08667709B2
公开(公告)日：2014-03-11
申请号：US13606771
申请日：2012-09-07
申请人： Frampton E. Ellis
发明人： Frampton E. Ellis
IPC分类号： A43B17/00 , A43B19/00
CPC分类号： A43B13/14 , A43B3/0005 , A43B7/142 , A43B7/1425 , A43B7/1435 , A43B7/144 , A43B7/148 , A43B13/00 , A43B13/187 , A43B13/189 , A43B13/203 , A43B13/36 , A43B13/38 , A43B13/40 , A43B17/035
摘要： This invention relates generally to footwear with a shoe sole, including at least one insertable midsole orthotic. The insertable midsole orthotic is removably inserted within the shoe upper, the sides of which hold it in position. The shoe sole includes a concavely rounded side or underneath portion, which may be formed in part by the insertable midsole orthotic. The insertable midsole orthotic may extend the length of the shoe sole or may form only a part of the shoe sole and can incorporate cushioning or structural compartments or components. The insertable midsole orthotic permits replacement of midsole material which has degraded or has worn out in order to maintain optimal characteristics of the shoe sole and allows customization for the individual wearer to provide tailored cushioning or support characteristics for the purpose of orthopedic, podiatric, corrective, prescriptive, therapeutic and/or prosthetic purposes.
摘要翻译：本发明一般涉及具有鞋底的鞋类，其包括至少一个可插入的中底矫正器。可插入的中底矫正器可拆卸地插入鞋上，其侧面将其固定就位。鞋底包括凹入圆形的侧面或下部，其可部分地由可插入的中底矫正部形成。可插入的中底矫正器可以延伸鞋底的长度或者可以仅形成鞋底的一部分并且可以包括缓冲或结构隔室或部件。可插入的中底矫正器允许更换已经退化或已经磨损的中底材料，以便保持鞋底的最佳特性，并且允许个体佩戴者定制为矫形，足底，矫正，规定，治疗和/或假肢目的。

90. 发明授权

US08664984B2 Pulse synchronizer circuit 有权
标题翻译：脉冲同步电路
公开(公告)号：US08664984B2
公开(公告)日：2014-03-04
申请号：US13485982
申请日：2012-06-01
申请人： Tony S. El-Kik
发明人： Tony S. El-Kik
IPC分类号： H03L7/00
CPC分类号： G06F1/12
摘要： A pulse synchronizer circuit converts an input data signal generated under a source-clock domain into an output data signal under a destination-clock domain, where the destination clock is independent of the source clock. The pulse synchronizer circuit successfully converts each data pulse in the input data signal into a corresponding data pulse in the output data signal when the source clock is faster than the destination clock, when the source clock is slower than the destination clock, when an input data pulse has a duration of one source-clock cycle, and when an input data pulse has a duration of multiple source-clock cycles. The pulse synchronizer circuit has source-domain circuitry and destination-domain circuitry. The source-domain circuitry detects input data pulses and determines whether they are single- or multi-cycle data pulses. The destination-domain circuitry generates output data pulses based on the processing of the source-domain circuitry.
摘要翻译：脉冲同步器电路将源 - 时钟域下生成的输入数据信号转换成目的时钟域下的输出数据信号，其中目的时钟独立于源时钟。当源时钟比目的地时钟慢，当源时钟比目的地时钟慢时，脉冲同步器电路成功地将输入数据信号中的每个数据脉冲转换成输出数据信号中的相应数据脉冲，当输入数据脉冲具有一个源时钟周期的持续时间，并且当输入数据脉冲具有多个源时钟周期的持续时间时。脉冲同步器电路具有源极域电路和目标域电路。源域电路检测输入数据脉冲，并确定它们是单周期还是多周期数据脉冲。目标域电路基于源域电路的处理产生输出数据脉冲。

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