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    • 1. 发明申请
    • GUIDEWIRE
    • US20080114303A1
    • 2008-05-15
    • US11869195
    • 2007-10-09
    • Anthony Tremaglio
    • Anthony Tremaglio
    • A61M25/09
    • A61M25/09A61M2025/0915
    • A guidewire may include opposing tip portions and two mid-shaft portions adjacent each other and the tip portions. The tip portions each may be relatively less stiff than either mid-shaft portion. The outer cross-sectional profile dimension may be generally uniform across the length of mid-shaft portions. The opposing tip portions may have about the same or smaller cross-sectional profile dimension relative to either mid-shaft portion. The guidewire may have a length and stiffness for each mid-shaft portion that enables the guidewire to be reversibly inserted, with one or the other opposing tip portion leading the way, into a predetermined body passage of a patient. The inventive subject matter is further directed to methods of using a reversible guidewire in a procedure conducted on a patient.
    • 引导线可以包括彼此相邻的相对的尖端部分和两个中间轴部分以及尖端部分。 每个尖端部分可以比中间轴部分相对较硬。 外横截面轮廓尺寸可以在中轴部分的长度上大致均匀。 相对的末端部分可以具有相对于任一中轴部分具有大致相同或更小的横截面轮廓尺寸。 导丝可以具有每个中轴部分的长度和刚度,使得导线能够以一个或另一个相对的末端部分引导到患者的预定身体通道中,使其能够可逆地插入。 本发明的主题还涉及在对患者进行的过程中使用可逆导丝的方法。
    • 4. 发明申请
    • Atraumatic ureteral access sheath
    • 无创输尿管通路鞘
    • US20050228361A1
    • 2005-10-13
    • US11105808
    • 2005-04-13
    • Anthony Tremaglio
    • Anthony Tremaglio
    • A61M25/00A61M25/01
    • A61M25/0045A61M25/0017A61M25/0053A61M25/0054A61M25/0108A61M2025/0004
    • A ureteral access sheath having nonuniform axial-stiffness adapted for proximal pushability needed for placement while also having distal flexibility to minimize trauma to the body lumen and ureter. Embodiments in accordance with the present invention provide a nonuniform axial-stiffness ureteral access sheath comprising a nonuniform axial-stiffness jacket encapsulating the reinforcement layer with the inner liner. Other embodiments in accordance with the present invention provide a nonuniform axial-stiffness ureteral access sheath comprising a nonuniform axial-stiffness reinforcement layer encapsulated between a single axial-stiffness jacket and the inner liner. Other embodiments in accordance with the present invention provide a nonuniform axial-stiffness ureteral access sheath comprising a nonuniform axial-stiffness jacket encapsulating a nonuniform axial-stiffness reinforcement layer with the inner liner.
    • 输尿管进入护套具有不均匀的轴向刚度,适用于放置所需的近端推进性,同时还具有远端柔性以最小化对体腔和输尿管的创伤。 根据本发明的实施例提供了一种不均匀的轴向刚度输尿管进入护套,其包括将增强层与内衬层包封的不均匀的轴向刚性护套。 根据本发明的其它实施例提供了一种不均匀的轴向刚度输尿管进入护套,其包含一个包封在单个轴向刚度护套和内衬之间的不均匀的轴向刚度增强层。 根据本发明的其它实施例提供了一种不均匀的轴向刚度输尿管进入护套,其包括将不均匀的轴向刚度加强层与内衬层包封的不均匀的轴向刚度护套。
    • 5. 发明申请
    • Atraumatic Ureteral Access Sheath
    • 无创性输尿管接触护套
    • US20130324972A1
    • 2013-12-05
    • US13961950
    • 2013-08-08
    • Rich FahertyAnthony Tremaglio
    • Rich FahertyAnthony Tremaglio
    • A61M25/00
    • A61M25/0053A61M25/0012A61M25/0017A61M25/0045A61M25/0054A61M25/0108A61M25/0662A61M2025/0004
    • Ureteral access sheaths can have a nonuniform axial-stiffness. A nonuniform axial-stiffness ureteral access sheath can have an inner liner defining a longitudinally extending and generally uniform bore. A non-uniform axial-stiffness outer jacket can define a longitudinally tapered outer surface, and a reinforcement layer can be encapsulated between the inner liner and the non-uniform axial-stiffness outer jacket. The reinforcement layer can have a non-uniform axial-stiffness. For example, a proximal portion of the reinforcement layer can be thicker than a distal portion of the reinforcement layer. A coil of wire can be included in the reinforcement layer, and a diameter of the wire in a proximal portion of the reinforcement layer can be larger than a diameter of the wire in a distal portion of the reinforcement layer. In some instances, the diameter of the wire tapers from the proximal portion to the distal portion.
    • 输尿管通路鞘可能具有不均匀的轴向刚度。 不均匀的轴向刚度输尿管进入护套可以具有限定纵向延伸且大致均匀的孔的内衬。 不均匀的轴向刚度外护套可以限定纵向渐缩的外表面,并且加强层可以封装在内衬和不均匀的轴向刚度外护套之间。 加强层可以具有不均匀的轴向刚度。 例如,加强层的近侧部分可以比加强层的远侧部分更厚。 线圈可以包括在加强层中,并且加强层的近端部分中的线的直径可以大于加强层的远侧部分中的线的直径。 在一些情况下,线的直径从近端部分到远端部分变细。
    • 10. 发明授权
    • Atraumatic ureteral access sheath
    • 无创输尿管通路鞘
    • US08535293B2
    • 2013-09-17
    • US13170060
    • 2011-06-27
    • Rich FahertyAnthony Tremaglio
    • Rich FahertyAnthony Tremaglio
    • A61M25/00
    • A61M25/0053A61M25/0012A61M25/0017A61M25/0045A61M25/0054A61M25/0108A61M25/0662A61M2025/0004
    • Ureteral access sheaths can have a nonuniform axial-stiffness. A nonuniform axial-stiffness ureteral access sheath can have an inner liner defining a longitudinally extending and generally uniform bore. A non-uniform axial-stiffness outer jacket can define a longitudinally tapered outer surface, and a reinforcement layer can be encapsulated between the inner liner and the non-uniform axial-stiffness outer jacket. The reinforcement layer can have a non-uniform axial-stiffness. For example, a proximal portion of the reinforcement layer can be thicker than a distal portion of the reinforcement layer. A coil of wire can be included in the reinforcement layer, and a diameter of the wire in a proximal portion of the reinforcement layer can be larger than a diameter of the wire in a distal portion of the reinforcement layer. In some instances, the diameter of the wire tapers from the proximal portion to the distal portion.
    • 输尿管通路鞘可能具有不均匀的轴向刚度。 不均匀的轴向刚度输尿管进入护套可以具有限定纵向延伸且大致均匀的孔的内衬。 不均匀的轴向刚度外护套可以限定纵向渐缩的外表面,并且加强层可以封装在内衬和不均匀的轴向刚度外护套之间。 加强层可以具有不均匀的轴向刚度。 例如,加强层的近侧部分可以比加强层的远侧部分更厚。 线圈可以包括在加强层中,并且加强层的近端部分中的线的直径可以大于加强层的远侧部分中的线的直径。 在一些情况下,线的直径从近端部分到远端部分变细。