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1. 发明授权

US06577885B1 Method for determining analyte concentration using periodic temperature modulation and phase detection 失效
公开(公告)号：US06577885B1
公开(公告)日：2003-06-10
申请号：US09663114
申请日：2000-09-15
申请人： James R. Braig , Charles E. Kramer , Bernhard B. Sterling , Daniel S. Goldberger , Peng Zheng , Arthur M. Shulenberger , Rick Trebino , Richard A. King , Casper W. Barnes
发明人： James R. Braig , Charles E. Kramer , Bernhard B. Sterling , Daniel S. Goldberger , Peng Zheng , Arthur M. Shulenberger , Rick Trebino , Richard A. King , Casper W. Barnes
IPC分类号： A61B500
CPC分类号： A61B5/0059 , G01N21/35
摘要： A method of determining the analyte concentration of a test sample is described. A temperature gradient is introduced in the test sample and infrared radiation detectors measure radiation at selected analyte absorbance peak and reference wavelengths. Reference and analytical signals are detected. In the presence of the selected analyte, parameter differences between reference and analytical signals are detectable. These parameter differences, having a relationship to analyte concentration, are measured, correlated, and processed to determine analyte concentration in the test sample. Accuracy is enhanced by inducing a periodically modulated temperature gradient in the test sample. The analytical and reference signals may be measured continuously and the parameter difference integrated over the measurement period to determine analyte concentration.

2. 发明授权

US06556850B1 Method for determining analyte concentration using periodic temperature modulation and phase detection 失效
标题翻译：使用周期性温度调制和相位检测来确定分析物浓度的方法
公开(公告)号：US06556850B1
公开(公告)日：2003-04-29
申请号：US09663071
申请日：2000-09-15
申请人： James R. Braig , Charles E. Kramer , Bernhard B. Sterling , Daniel S. Goldberger , Peng Zheng , Arthur M. Shulenberger , Rick Trebino , Richard A. King , Casper W. Barnes
发明人： James R. Braig , Charles E. Kramer , Bernhard B. Sterling , Daniel S. Goldberger , Peng Zheng , Arthur M. Shulenberger , Rick Trebino , Richard A. King , Casper W. Barnes
IPC分类号： A61B500
CPC分类号： A61B5/0059 , G01N21/35
摘要： A method of determining the analyte concentration of a test sample is described. A temperature gradient is introduced in the test sample and infrared radiation detectors measure radiation at selected analyte absorbance peak and reference wavelengths. Reference and analytical signals are detected. In the presence of the selected analyte, parameter differences between reference and analytical signals are detectable. These parameter differences, having a relationship to analyte concentration, are measured, correlated, and processed to determine analyte concentration in the test sample. Accuracy is enhanced by inducing a periodically modulated temperature gradient in the test sample. The analytical and reference signals may be measured continuously and the parameter difference integrated over the measurement period to determine analyte concentration.
摘要翻译：描述了确定测试样品的分析物浓度的方法。在测试样品中引入温度梯度，红外辐射检测器测量所选分析物的吸收峰和参考波长的辐射。检测参考和分析信号。在所选分析物的存在下，参考和分析信号之间的参数差异是可检测的。测量，相关和处理与分析物浓度有关系的这些参数差异，以确定测试样品中的分析物浓度。通过在测试样品中诱导周期调制的温度梯度来提高精度。可以连续测量分析和参考信号，并在测量周期内积分参数差异，以确定分析物浓度。

3. 发明授权

US4676250A Method and apparatus for estimating the attenuation-vs-frequency slope of a propagation medium from the complex envelope of a signal 失效
标题翻译：用于从信号的复包估计传播介质的衰减与频率斜率的方法和装置
公开(公告)号：US4676250A
公开(公告)日：1987-06-30
申请号：US795801
申请日：1985-11-07
申请人： Casper W. Barnes
发明人： Casper W. Barnes
IPC分类号： G10K11/00 , A61B8/00 , A61B8/08 , G01N29/24 , G01S7/52 , G01N29/00
CPC分类号： G01S7/5206 , G01S7/52036
摘要： An ultrasound attenuation scanner measures the local attenuation of tissues from pulse echo A-line data. An adaptive filter with a transfer function which is the inverse of the tissue undergoing examination operates on the complex envelope of the RF signal.
摘要翻译：超声波衰减扫描仪从脉冲回波A线数据测量组织的局部衰减。具有传递函数的自适应滤波器，其是正在进行检查的组织的倒数，其操作在RF信号的复包络上。

4. 发明授权

US06580934B1 Method and apparatus for determining analyte concentration using phase and magnitude detection of a radiation transfer function 失效
标题翻译：使用辐射传递函数的相位和幅度检测来确定分析物浓度的方法和装置
公开(公告)号：US06580934B1
公开(公告)日：2003-06-17
申请号：US09538164
申请日：2000-03-30
申请人： James R. Braig , Charles E. Kramer , Bernhard B. Sterling , Daniel S. Goldberger , Peng Zheng , Arthur M. Shulenberger , Rick Trembino , Richard A. King , Casper W. Barnes
发明人： James R. Braig , Charles E. Kramer , Bernhard B. Sterling , Daniel S. Goldberger , Peng Zheng , Arthur M. Shulenberger , Rick Trembino , Richard A. King , Casper W. Barnes
IPC分类号： A61B500
CPC分类号： A61B5/0059 , G01N21/35
摘要： A method and apparatus of determining the analyte concentration of a test sample is described. A temperature gradient is introduced in the test sample and infrared radiation detectors measure radiation at selected analyte absorbance peak and reference wavelengths. The modulation of the temperature gradient is controlled by a surface temperature modulation. A transfer function is determined that relates the surface temperature modulation to the modulation of the measured infrared radiation. Reference and analytical signals are detected. In the presence of the selected analyte, phase and magnitude differences in the transfer function are detected. These phase and magnitude differences, having a relationship to analyte concentration, are measured, correlated, and processed to determine analyte concentration in the test sample.
摘要翻译：描述了测定试样的分析物浓度的方法和装置。在测试样品中引入温度梯度，红外辐射检测器测量所选分析物的吸收峰和参考波长的辐射。温度梯度的调制由表面温度调制控制。确定将表面温度调制与所测量的红外辐射的调制相关联的传递函数。检测参考和分析信号。在所选分析物的存在下，检测到传递函数中的相位和幅度差异。测量，相关和处理与分析物浓度关系的这些相位和幅度差异，以确定测试样品中的分析物浓度。

5. 发明授权

US6161028A Method for determining analyte concentration using periodic temperature modulation and phase detection 失效
公开(公告)号：US6161028A
公开(公告)日：2000-12-12
申请号：US267121
申请日：1999-03-10
申请人： James R. Braig , Charles E. Kramer , Bernhard B. Sterling , Daniel S. Goldberger , Peng Zheng , Arthur M. Shulenberger , Rick Trebino , Richard A. King , Casper W. Barnes
发明人： James R. Braig , Charles E. Kramer , Bernhard B. Sterling , Daniel S. Goldberger , Peng Zheng , Arthur M. Shulenberger , Rick Trebino , Richard A. King , Casper W. Barnes
IPC分类号： A61B5/00 , G01N21/35
CPC分类号： A61B5/0059 , G01N21/35
摘要： A method of determining the analyte concentration of a test sample is described. A temperature gradient is introduced in the test sample and infrared radiation detectors measure radiation at selected analyte absorbance peak and reference wavelengths. Reference and analytical signals are detected. In the presence of the selected analyte, parameter differences between reference and analytical signals are detectable. These parameter differences, having a relationship to analyte concentration, are measured, correlated, and processed to determine analyte concentration in the test sample. Accuracy is enhanced by inducing a periodically modulated temperature gradient in the test sample. The analytical and reference signals may be measured continuously and the parameter difference integrated over the measurement period to determine analyte concentration.

6. 发明授权

US4761752A Fractional step correlator 失效
标题翻译：分数级相关器
公开(公告)号：US4761752A
公开(公告)日：1988-08-02
申请号：US854260
申请日：1986-04-21
申请人： Casper W. Barnes
发明人： Casper W. Barnes
IPC分类号： A61B8/06 , G01S7/52 , G01S15/89 , G06F17/15 , G06F15/336
CPC分类号： G01S15/8979 , A61B8/06 , G01S7/52026 , G06F17/15
摘要： A circuit for determining the cross-correlation function between two digitally sampled signals comprises a plurality of fractional step delay (FSD) digital interpolation filters which estimate the value of one of said input signals at intervals between said samples and a plurality of correlation circuits each of which determines the correlation between the first signal and the output of one of said interpolation filters.
摘要翻译：用于确定两个数字采样信号之间的互相关函数的电路包括多个分数阶延迟（FSD）数字内插滤波器，其以所述采样之间的间隔估计所述输入信号之一的值和多个相关电路其确定第一信号与所述插值滤波器之一的输出之间的相关性。

7. 发明授权

US4100927A Fluid flow regulation 失效
标题翻译：流体流量调节
公开(公告)号：US4100927A
公开(公告)日：1978-07-18
申请号：US697419
申请日：1976-06-18
申请人： Casper W. Barnes, Jr.
发明人： Casper W. Barnes, Jr.
IPC分类号： F02M9/00 , F02M7/127 , F02M7/16 , F02M7/20 , F02M9/10 , F02M11/00 , F23N1/02 , G05D7/01 , G05D11/03
CPC分类号： F02M9/103 , F02M7/16 , G05D7/01 , Y10S261/67 , Y10S261/78 , Y10T137/0363 , Y10T137/7791 , Y10T137/88046
摘要： Flow regulating apparatus comprises a turbulent-flow valve with a fluid supply connected at the upstream side thereof. A fixed pressure bias is applied to the fluid upstream of the valve whereby the mass flow rate of fluid through the valve is directly proportional to the pressure differential across the apparatus when these variations are within a selected pressure range. Such flow regulation may be used in a system for introducing a metered amount of liquid fuel into an air stream to provide a combustible air-fuel mixture having a substantially constant air-to-fuel ratio. With this system air is passed through a constricted zone to increase its velocity to sonic, and the area of the constricted zone is varied in correlation with operating demands imposed upon the engine for which the mixture is produced. A liquid fuel supply is under the influence of atmospheric pressure, and fuel is metered from the supply into the air stream by controlling a fuel valve of the turbulent-flow type in direct proportion to the area of the constricted zone, the fuel valve being exposed to the pressure of the air stream. The fixed pressure bias is applied to the liquid fuel supply so that the mass flow rate of fuel through the valve varies in direct proportion with variations in atmospheric pressure.

8. 发明授权

US06731961B2 Method for transforming phase spectra to absorption spectra 失效
公开(公告)号：US06731961B2
公开(公告)日：2004-05-04
申请号：US10291912
申请日：2002-11-08
申请人： James R. Braig , W. Dale Hall , Casper W. Barnes , Peng Zheng , Jennifer H. Gable
发明人： James R. Braig , W. Dale Hall , Casper W. Barnes , Peng Zheng , Jennifer H. Gable
IPC分类号： A61B500
CPC分类号： A61B5/1455 , A61B5/14532 , A61B5/14546 , A61B5/1491 , G01N21/1717 , G01N21/35 , G01N21/3577 , G01N21/71
摘要： A device and method for determining analyte concentrations within a material sample are provided. A modulating temperature gradient is induced in the sample and resultant, emitted infrared radiation is measured at selected analyte absorbance peaks and reference wavelengths. The modulating temperature gradient is controlled by a surface temperature modulation. One embodiment provides a transfer function relating the surface temperature modulation to a modulation of the measured infrared radiation. Phase and magnitude differences in the transfer function are detected in the presence of the sought-after analyte. These phase and magnitude differences, having a relationship to analyte concentration, are measured, correlated and processed to determine analyte concentration in the material sample. Another embodiment provides a method for transforming thermal phase spectra to absorption spectra for consistent determination of analyte concentration within the sample.

9. 发明授权

US4512196A Ultrasound imaging with FM detection 失效
标题翻译：超声成像与FM检测
公开(公告)号：US4512196A
公开(公告)日：1985-04-23
申请号：US538021
申请日：1983-09-30
申请人： Casper W. Barnes
发明人： Casper W. Barnes
IPC分类号： A61B8/14 , A61B8/00 , G01S15/89 , G01N29/00
CPC分类号： G01S15/8954
摘要： An ultrasound transducer having an annular acoustic aperture is utilized in combination with an echo-ultrasound imaging system having an FM detector. The off-axis transfer function characteristics of the annular transducer substantially improve the lateral resolution of the imaging system as compared with prior art systems which utilized round or rectangular transducer apertures.
摘要翻译：具有环形声孔的超声换能器与具有FM检测器的回波超声成像系统结合使用。与使用圆形或矩形换能器孔的现有技术系统相比，环形换能器的离轴传递函数特性基本上提高了成像系统的横向分辨率。

10. 发明授权

US3987132A Fluid flow regulation 失效
标题翻译：流体流量调节
公开(公告)号：US3987132A
公开(公告)日：1976-10-19
申请号：US485517
申请日：1974-07-03
申请人： Casper W. Barnes, Jr.
发明人： Casper W. Barnes, Jr.
IPC分类号： F02M9/00 , F02M7/127 , F02M7/16 , F02M7/20 , F02M9/10 , F02M11/00 , F23N1/02 , G05D7/01 , G05D11/03
CPC分类号： F02M9/103 , F02M7/16 , G05D7/01 , Y10S261/67 , Y10S261/78 , Y10T137/0363 , Y10T137/7791 , Y10T137/88046
摘要： Flow regulating apparatus comprises a turbulent-flow valve with a fluid supply connected at the upstream side thereof. A fixed pressure bias is applied to the fluid upstream of the valve whereby the mass flow rate of fluid through the valve is directly proportional to the pressure differential across the apparatus when these variations are within a selected pressure range. Such flow regulation may be used in a system for introducing a metered amount of liquid fuel into an air stream to provide a combustible air-fuel mixture having a substantially constant air-to-fuel ratio. With this system air is passed through a constricted zone to increase its velocity to sonic, and the area of the constricted zone is varied in correlation with operating demands imposed upon the engine for which the mixture is produced. A liquid fuel supply is under the influence of atmospheric pressure, and fuel is metered from the supply into the air stream by controlling a fuel valve of the turbulent-flow type in direct proportion to the area of the constricted zone, the fuel valve being exposed to the pressure of the air stream. The fixed pressure bias is applied to the liquid fuel supply so that the mass flow rate of fuel through the valve varies in direct proportion with variations in atmospheric pressure.
摘要翻译：流量调节装置包括在其上游侧连接有流体供应的湍流阀。固定的压力偏压被施加到阀上游的流体，由此当这些变化在选择的压力范围内时，通过阀的流体的质量流速与装置两端的压差成正比。这种流量调节可以用于将计量的液体燃料引入空气流中以提供具有基本恒定的空气 - 燃料比的可燃空气 - 燃料混合物的系统。利用该系统，空气通过收缩区域以将其速度增加到声音，并且收缩区域的面积与施加于混合物产生的发动机的操作要求相关。液体燃料供应受大气压力的影响，通过与遏制区域的区域成正比地控制湍流型燃料阀，将燃料从供给气流中计量，燃料阀暴露到气流的压力。固定的压力偏压被施加到液体燃料供应，使得通过阀门的燃料的质量流量与大气压力的变化成正比地变化。

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