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1. 发明授权

US08241216B2 Coherent image formation for dynamic transmit beamformation 有权
标题翻译：用于动态发射波束形成的相干图像形成
公开(公告)号：US08241216B2
公开(公告)日：2012-08-14
申请号：US12477783
申请日：2009-06-03
申请人： Rickard C. Loftman , Kutay F. Ustuner , Charles E. Bradley
发明人： Rickard C. Loftman , Kutay F. Ustuner , Charles E. Bradley
IPC分类号： A61B8/00
CPC分类号： G01S7/52046 , G01S7/5202 , G01S7/5209 , G01S7/52095 , G10K11/346
摘要： Retrospective dynamic transmit beamformation is provided in medical ultrasound imaging. Using parallel receive beamformation, sets of data representing locations in at least a common field of view are obtained, each set in response to a transmit with a spatially distinct phase front. The common field of view receive data are time aligned and amplitude weighted for retrospective transmit focusing and retrospective transmit apodization, respectively. A time offset, such as of a cycle or more in some cases, is applied to the receive data for retrospective transmit focusing. The offset is selected to emulate shifting the transmit delay profile to be tangentially intersecting with the dynamic receive delay profile for each location which is the desired transmit delay profile. A weight is applied to the receive data for retrospective transmit apodization. The weight is selected based on the desired transmit apodization profile. The offset and weighted data representing a same location from different transmit events is coherently combined. The number of sets of data offset, weighted and combined may vary as a function of depth for dynamic transmit beamformation.
摘要翻译：在医学超声成像中提供回溯动态发射波束形成。使用并行接收波束形成，获得在至少公共视场中表示位置的数据集合，每个集合响应于具有空间上不同相位前沿的传输。对于追溯发射聚焦和追溯发射变迹，共同视野接收数据分别对时间对齐和幅度加权。在一些情况下，例如周期或更多的时间偏移被应用于用于追溯发射聚焦的接收数据。选择该偏移以模拟将发射延迟分布移动为与期望的发射延迟分布的每个位置的动态接收延迟分布切线相交。将加权应用于接收数据用于追溯发射变迹。基于所需的发射变迹轮廓来选择权重。表示来自不同发送事件的相同位置的偏移和加权数据被一致地组合。数据偏移量，加权和组合的数量可以随动态传输波束形成的深度而变化。

2. 发明授权

US06517489B1 Method and apparatus for forming medical ultrasound images 有权
标题翻译：用于形成医学超声图像的方法和装置
公开(公告)号：US06517489B1
公开(公告)日：2003-02-11
申请号：US09839709
申请日：2001-04-19
申请人： Patrick J. Phillips , Kutay F. Ustuner , Charles E. Bradley , Lewis J. Thomas , David J. Napolitano
发明人： Patrick J. Phillips , Kutay F. Ustuner , Charles E. Bradley , Lewis J. Thomas , David J. Napolitano
IPC分类号： A61B814
CPC分类号： G01S7/52026 , G01S7/52049 , G01S15/8909 , G01S15/8959
摘要： A medical ultrasonic imaging method uses transmitted plane waves, or transmitted wavefronts that are substantially planar, to improve contrast agent imaging by generating peak pressures that are more uniform over depth. Depending on the type of contrast agent, the returned frequencies of interest, and the desired strength of the non-linear response, multiple wavefronts can be generated at substantially the same time to increase peak pressures.
摘要翻译：医疗超声成像方法使用透射平面波或基本上平面的透射波前，通过产生在深度上更均匀的峰值压力来改善造影剂成像。根据造影剂的类型，返回的感兴趣的频率和非线性响应的期望强度，可以在基本相同的时间产生多个波前以增加峰值压力。

3. 发明授权

US06436046B1 Diagnostic ultrasound imaging method and system with improved frame rate 有权
标题翻译：诊断超声成像方法和系统，帧率提高
公开(公告)号：US06436046B1
公开(公告)日：2002-08-20
申请号：US09698995
申请日：2000-10-27
申请人： David J. Napolitano , Christopher R. Cole , Gregory L. Holley , John A. Hossack , Charles E. Bradley , Patrick Phillips
发明人： David J. Napolitano , Christopher R. Cole , Gregory L. Holley , John A. Hossack , Charles E. Bradley , Patrick Phillips
IPC分类号： A61B800
CPC分类号： G01S15/8963 , A61B8/00 , G01S7/52039 , G01S7/52046 , G01S7/52085 , G01S7/52095 , G01S15/8927 , G01S15/8959 , G01S15/8977
摘要： A medical diagnostic ultrasonic imaging system acquires receive beams from spatially distinct transmit beams. The receive beams alternate in type between at least first and second types across the region being imaged. The first and second types of receive beams differ in at least one scan parameter other than transmit and receive line geometry, and can for example differ in transmit phase, transmit or receive aperture, system frequency, transmit focus, complex phase angle, transmit code or transmit gain. Receive beams associated with spatially distinct ones of the transmit beams (including at least one beam of the first type and at least one beam of the second type) are then combined. In this way, many two-pulse techniques, including, for example, phase inversion techniques, synthetic aperture techniques, synthetic frequency techniques, and synthetic focus techniques, can be used while substantially reducing the frame rate penalty normally associated with such techniques.
摘要翻译：医疗诊断超声成像系统从空间上不同的发射波束获取接收波束。接收波束在被成像的区域之间在至少第一和第二类型之间交替类型。第一和第二类型的接收波束在除发射和接收线几何之外的至少一个扫描参数不同，并且例如可以在发射相位，发射或接收孔径，系统频率，发射焦点，复相位角，发射码或传输增益。然后组合与空间上不同的发射波束（包括第一类型的至少一个波束和第二类型的至少一个波束）相关联的接收波束。以这种方式，可以使用许多双脉冲技术，包括例如相位反转技术，合成孔径技术，合成频率技术和合成焦点技术，同时显着降低通常与这种技术相关联的帧速率损失。

4. 发明授权

US08641628B2 Aperture synthesis using cMUTs 有权
标题翻译：使用cMUT进行孔径合成
公开(公告)号：US08641628B2
公开(公告)日：2014-02-04
申请号：US11904454
申请日：2007-09-26
申请人： Charles E. Bradley , Christopher M. Daft , Paul A. Wagner , Satchi Panda
发明人： Charles E. Bradley , Christopher M. Daft , Paul A. Wagner , Satchi Panda
IPC分类号： A61B8/00
CPC分类号： G01S15/8927 , G01S15/8925 , G01S15/8959 , G01S15/8995 , G01S15/8997
摘要： An ultrasound imaging system may use a capacitive membrane or electrostrictive ultrasound transducer to realize isotropic volumetric imaging with bias-line element selection and a variety of aperture synthesis techniques. Two dimensional beam formation may be performed by using a beamformer to focus along one dimension, and then perform a second round of “off-line” or “retrospective” beam formation along the other direction.
摘要翻译：超声成像系统可以使用电容膜或电致伸缩超声换能器来实现具有偏置线元件选择和各种孔合成技术的各向同性体积成像。可以通过使用波束形成器沿着一个维度聚焦来执行二维波束形成，然后沿着另一个方向执行第二轮“离线”或“回溯”波束形成。

5. 发明授权

US07946990B2 Ultrasound color flow imaging at high frame rates 有权
标题翻译：超声波彩色流量成像在高帧速率
公开(公告)号：US07946990B2
公开(公告)日：2011-05-24
申请号：US11242162
申请日：2005-09-30
申请人： Seshadri Srinivasan , Patrick J. Phillips , Charles E. Bradley
发明人： Seshadri Srinivasan , Patrick J. Phillips , Charles E. Bradley
IPC分类号： A61B8/00 , A61B8/14
CPC分类号： G01S15/584 , A61B8/06 , A61B8/13 , A61B8/54 , G01S7/52085 , G01S7/5209 , G01S7/52092 , G01S7/52095 , G01S15/8979
摘要： A method is provided to improve the frame-rate in color-flow ultrasound imaging using simultaneous spatially-distinct transmit beams with one or more frequency bands per transmit beam. Pulses of different center frequencies are used simultaneously in different (lateral and/or elevational) directions, thereby reducing the scanning time and improving the frame-rates. Optionally, a multi-modal pulse is used, and flow is estimated separately for the different frequencies. The flow estimates for these pulses are appropriately combined to improve low-velocity sensitivity and to reduce aliasing. A flow sample count with two or more different pulse repetition intervals can be used to further improve low-flow sensitivity and minimize aliasing.
摘要翻译：提供了一种用于使用每个发射波束具有一个或多个频带的同时空间不同的发射波束来改善彩色流超声成像中的帧频的方法。不同中心频率的脉冲同时在不同（横向和/或正向）方向使用，从而减少扫描时间并提高帧速率。可选地，使用多模式脉冲，并且针对不同频率分别估计流量。适当地组合这些脉冲的流量估计以改善低速灵敏度并减少混叠。可以使用具有两个或多个不同脉冲重复间隔的流量样本计数来进一步改善低流量灵敏度并最小化混叠。

6. 发明授权

US06905467B2 Ultrasonic harmonic imaging system and method using waveform pre-distortion 有权
标题翻译：超声波谐波成像系统及方法采用波形预失真
公开(公告)号：US06905467B2
公开(公告)日：2005-06-14
申请号：US09884407
申请日：2001-06-18
申请人： Charles E. Bradley , Gregory L. Holley , Lawrence J. Newell , David J. Hedberg , Dave Napolitano
发明人： Charles E. Bradley , Gregory L. Holley , Lawrence J. Newell , David J. Hedberg , Dave Napolitano
IPC分类号： G01S7/52 , G01S15/89 , A61B8/00
CPC分类号： G01S7/52039 , G01S7/52038 , G01S7/52046 , G01S15/895
摘要： Improvements to a method for imaging a target, which method including the steps of (a) transmitting ultrasonic energy at a fundamental frequency, (b) receiving reflected ultrasonic energy at a harmonic of the fundamental frequency and (c) generating an image responsive to reflected energy at the harmonic, are provided. The transmitting step includes transmitting a waveform with a positive pulse spatially defined by first and second zero values. A positive peak amplitude of the positive pulse is a first distance from the first zero value that is less than half a second distance between said first and second zero values. Thus, the waveform includes a fundamental spectral component and a harmonic spectral component at the transducer. An attenuation normalized peak of the harmonic spectral component is reduced at a region spaced from the transducer as compared to the peak at a region adjacent to the transducer. A negative peak is also shifted or pre-distorted. Various pre-distortions of the waveform may compensate for propagation, scattering, or system non-linearities.
摘要翻译：用于对目标成像的方法的改进，该方法包括以下步骤：（a）以基本频率发送超声能量，（b）在基频谐波处接收反射的超声波能量，以及（c）响应于反射的提供谐波的能量。发送步骤包括以由第一和第二零值空间定义的正脉冲发送波形。正脉冲的正峰值振幅是与第一零值之间的第一距离，该第一零值小于所述第一和第二零值之间的第二距离的一半。因此，波形包括传感器处的基本频谱分量和谐波频谱分量。与与换能器相邻的区域的峰值相比，谐振频谱分量的衰减归一化峰值在与换能器间隔的区域减小。负峰也被转移或预失真。波形的各种预失真可以补偿传播，散射或系统非线性。

7. 发明授权

US06641536B2 Medical diagnostic ultrasound imaging methods for extended field of view 有权
公开(公告)号：US06641536B2
公开(公告)日：2003-11-04
申请号：US10081662
申请日：2002-02-21
申请人： John A. Hossack , Linyong Pang , Thilaka S. Sumanaweera , John W. Allison , Kutay F. Ustuner , Charles E. Bradley
发明人： John A. Hossack , Linyong Pang , Thilaka S. Sumanaweera , John W. Allison , Kutay F. Ustuner , Charles E. Bradley
IPC分类号： A61B800
CPC分类号： G01S7/52034 , A61B8/06 , A61B8/12 , A61B8/13 , G01S7/5205 , G01S7/5206 , G01S7/52065 , G01S7/52071 , G01S7/52074 , G01S7/52085 , G01S15/8927 , G01S15/8979 , G06T3/0075 , G06T7/32 , G06T2207/10132 , G06T2207/30004 , G06T2207/30101
摘要： A medical diagnostic ultrasound imaging system aligns substantially co-planar two-dimensional images to form an extended field of view using improved compounding methods. Compounding with a finite impulse response is used for more versatile compositing. The compounding is adaptive, such as through adapting the image regions, weighting, or type of compounding as a function of correlation, location within the image, estimated motion or combinations thereof. A user warning is provided as a function of the correlation between images.

8. 发明授权

US06527720B1 Medical ultrasonic imaging method and system for spatial compounding 有权
标题翻译：医用超声成像方法及空间复合系统
公开(公告)号：US06527720B1
公开(公告)日：2003-03-04
申请号：US09962965
申请日：2001-09-24
申请人： Kutay F. Ustuner , Charles E. Bradley , Daniel E. Need
发明人： Kutay F. Ustuner , Charles E. Bradley , Daniel E. Need
IPC分类号： A61B800
CPC分类号： G01S15/8995 , A61B8/0858 , G01S7/52046
摘要： A medical imaging system provides increased detectability of targets such as membranes, tendons, muscle fibers and biopsy needles that have strong directional responses. This improved result is achieved by compounding multiple images generated by using only one or two transducer firings per ultrasound line. Speckle variance is also reduced as the result of spatial compounding, and this reduction improves the detectability of soft-tissue lesions.
摘要翻译：医学成像系统提供具有强定向反应的靶，例如膜，肌腱，肌肉纤维和活检针的增强的可检测性。这种改进的结果是通过使每个超声线仅使用一个或两个换能器发射而产生的多个图像来实现的。由于空间复合的结果，斑点差异也减少，这种降低提高了软组织病变的可检测性。

9. 发明授权

US06364835B1 Medical diagnostic ultrasound imaging methods for extended field of view 有权
标题翻译：医学诊断超声成像方法扩展视野
公开(公告)号：US06364835B1
公开(公告)日：2002-04-02
申请号：US09536215
申请日：2000-03-27
申请人： John A. Hossack , Linyong Pang , Thilaka S. Sumanaweera , John W. Allison , Kutay F. Ustuner , Charles E. Bradley
发明人： John A. Hossack , Linyong Pang , Thilaka S. Sumanaweera , John W. Allison , Kutay F. Ustuner , Charles E. Bradley
IPC分类号： A61B800
CPC分类号： G01S7/52034 , A61B8/06 , A61B8/12 , A61B8/13 , G01S7/5205 , G01S7/5206 , G01S7/52065 , G01S7/52071 , G01S7/52074 , G01S7/52085 , G01S15/8927 , G01S15/8979 , G06T3/0075 , G06T7/32 , G06T2207/10132 , G06T2207/30004 , G06T2207/30101
摘要： A medical diagnostic ultrasound imaging system aligns substantially co-planar two-dimensional images to form an extended field of view using improved compounding methods. Compounding with a finite impulse response is used for more versatile compositing. The compounding is adaptive, such as through adapting the image regions, weighting, or type of compounding as a function of correlation, location within the image, estimated motion or combinations thereof. A user warning is provided as a function of the correlation between images.
摘要翻译：医学诊断超声成像系统使用改进的复合方法对准基本上共面的二维图像以形成扩展的视场。使用有限脉冲响应进行复合用于更通用的合成。复合是自适应的，例如通过适应图像区域，加权或复合类型作为相关函数，图像内的位置，估计运动或其组合。作为图像之间的相关性的函数提供用户警告。

10. 发明授权

US06120448A Diagnostic medical ultrasonic imaging method and system for selectively processing harmonic and fundamental image information 有权
标题翻译：诊断医学超声成像方法和系统，用于选择性处理谐波和基本图像信息
公开(公告)号：US06120448A
公开(公告)日：2000-09-19
申请号：US255072
申请日：1999-02-22
申请人： Charles E. Bradley , Samuel H. Maslak
发明人： Charles E. Bradley , Samuel H. Maslak
IPC分类号： G01S7/52 , A61B8/00
CPC分类号： G01S7/52046 , G01S15/108 , G01S7/52036
摘要： A diagnostic medical ultrasonic imaging method and system form first and second signals as a function of the Nth power of the absolute value of first and second ultrasound receive signals. These receive signals are associated with respective first and second transmit pulses that differ in phase and are both associated with overlapping or nearby regions of a subject. A combined signal is formed as a function of the difference between the first and second signals. The low pass component of the absolute value of this combined signal is then applied to an image processor. This low pass component, depending upon the value of N, can correspond to the second harmonic component of the combined receive signals, to the product of the fundamental and second harmonic components of the combined receive signals, and other combinations of fundamental and harmonic components.
摘要翻译：诊断医疗超声成像方法和系统形成第一和第二信号作为第一和第二超声接收信号的绝对值的第N次幂的函数。这些接收信号与相位不同并且与被摄体的重叠或附近区域相关联的相应的第一和第二发射脉冲相关联。作为第一和第二信号之间的差的函数形成组合信号。然后将该组合信号的绝对值的低通分量施加到图像处理器。这个根据N值的低通分量可以对应于组合的接收信号的二次谐波分量，以及组合的接收信号的基波和二次谐波分量以及基波和谐波分量的其它组合的乘积。

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