专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US10413267B2 Method and apparatus for performing co-planar and simultaneous spectral CT and PET imaging 有权
公开(公告)号：US10413267B2
公开(公告)日：2019-09-17
申请号：US15584726
申请日：2017-05-02
申请人： Daniel Gagnon
发明人： Daniel Gagnon
IPC分类号： A61B6/00 , A61B6/02 , A61B6/03 , A61B6/10 , A61B5/055 , G01T1/161 , G01N23/046
摘要： A PET/CT imaging system is provided. The imaging system includes a PET detection system having a plurality of detector rings and an axial gap between at least two adjacent detector rings within the plurality of detector rings. The imaging system includes a CT system having an x-ray generator and a CT detection system positioned within the axial gap between the at least two detector rings. The system is configured to collect PET data and CT data on the same volume of interest substantially simultaneously.

2. 发明授权

US09445778B2 ECG-gated temporal sampling in cardiac kinetic modeling 有权
标题翻译：心电图门控时间采样心脏动力学建模
公开(公告)号：US09445778B2
公开(公告)日：2016-09-20
申请号：US11912678
申请日：2006-04-10
申请人： Daniel Gagnon , Henning Braess
发明人： Daniel Gagnon , Henning Braess
IPC分类号： A61B6/00 , A61B6/03 , A61B8/08 , A61B5/0275 , A61B5/00 , A61B8/00
CPC分类号： A61B6/541 , A61B5/02755 , A61B5/7289 , A61B6/037 , A61B6/5288 , A61B8/5276 , A61B8/543
摘要： In a diagnostic imaging system (10), a monitor (50) monitors periodic biological cycles of the subject (14). A trigger point detector (60) detects a time (t1, t2, . . . , tn) of a common, reoccurring reference point (R1, R2, . . . , Rn) in each periodic cycle of the subject (14). A sequence selector (62) selects a sequence (64) of nominal sampling segments (Si, S2, . . . , Sn). An adjustor (70) adjusts duration of each nominal sampling segment (Si, S2, . . . , Sn) to coincide with the times of detected reference points (R1, R2, . . . , Rn). A scaling processor (72) scales each adjusted segment based on a difference in duration between the corresponding nominal (Si, S2, . . . , Sn) and adjusted sampling segments (S′i, S′2, . . . , S′n).
摘要翻译：在诊断成像系统（10）中，监视器（50）监视对象（14）的周期性生物学周期。触发点检测器（60）检测对象（14）的每个周期循环中的共同的重现的参考点（R1，R2，...，Rn）的时间（t1，t2，...，tn）。序列选择器（62）选择标称采样段（Si，S2，...，Sn）的序列（64）。调整器（70）调整每个标称采样段（Si，S2，...，Sn）的持续时间，以与检测到的参考点（R1，R2，...，Rn）的时间一致。缩放处理器（72）基于相应的标称（Si，S2，...，Sn）和调整的采样段（S'i，S'2，...，S'）之间的持续时间差来缩放每个经调整的段， n）。

3. 发明授权

US09322929B2 PET imaging system including detector elements of different design and performance 有权
标题翻译： PET成像系统包括不同设计和性能的检测器元件
公开(公告)号：US09322929B2
公开(公告)日：2016-04-26
申请号：US13091722
申请日：2011-04-21
申请人： Daniel Gagnon
发明人： Daniel Gagnon
IPC分类号： G01T1/164 , G01T1/20 , G01T1/29 , A61B6/03
CPC分类号： G01T1/1644 , A61B6/037 , G01T1/2018 , G01T1/2985
摘要： A positron emission tomography (PET) scanner, including a first detector portion arranged circumferentially around a patient pallet, the first detector portion having a predetermined axial extent and transaxially subtending less than 360 degrees with respect to a central axis of the scanner defined by the first detector portion, wherein the first detector portion includes a plurality of first detector elements; and a second detector portion arranged separately from and opposing the first detector section, the second detector portion including a plurality of second detector elements, the second detector elements being of a different type than the first detector elements, wherein each of the first detector elements includes photomultiplier tubes (PMTs); and each of the second detector elements includes photosensors of a different type from the PMTs of the first detector elements.
摘要翻译：一种正电子发射断层摄影（PET）扫描仪，包括围绕患者托盘周向布置的第一检测器部分，第一检测器部分具有预定的轴向范围，并相对于由第一检测器限定的扫描仪的中心轴相对于小于360度检测器部分，其中第一检测器部分包括多个第一检测器元件; 以及第二检测器部分，其与第一检测器部分分开设置并相对于第二检测器部分，第二检测器部分包括多个第二检测器元件，第二检测器元件具有与第一检测器元件不同的类型，其中第一检测器元件包括光电倍增管（PMT）; 并且每个第二检测器元件包括与第一检测器元件的PMT不同类型的光电传感器。

4. 发明授权

US09176240B2 Apparatus and method for channel count reduction in solid-state-based positron emission tomography 有权
标题翻译：基于固态的正电子发射断层扫描的通道数减少的装置和方法
公开(公告)号：US09176240B2
公开(公告)日：2015-11-03
申请号：US13552155
申请日：2012-07-18
申请人： Daniel Gagnon , Sachin S. Junnarkar
发明人： Daniel Gagnon , Sachin S. Junnarkar
IPC分类号： G01T1/208 , G01T1/164
CPC分类号： G01T1/208 , G01T1/1647
摘要： An apparatus and method for channel count reduction in solid-state-based positron emission tomography that multiplexes read-outs from photo-detectors using a sum delay circuit, including a sum channel and a delay-sum channel. The sum channel sums signals from sensors in an array and is digitized to extract the timing and energy information. A delay-sum channel includes a discrete delay line that introduces a known delay after each sensor, creating a time signature for the sensor, followed by a summing circuit that adds the delayed signals. The delay-sum channel is digitized using a high speed counters to extract location information. Start and Stop signals for the counter are derived when the sum channel output and the delay-sum channel output cross a pulse ID threshold, respectively. The pulse ID threshold is chosen to minimize the Compton scatter and not clip the photo-peak events.
摘要翻译：一种用于基于固态的正电子发射断层摄影的通道数减少的装置和方法，其使用包括和通道和延迟和通道的和延迟电路复用来自光电检测器的读出。总和通道将来自阵列中的传感器的信号相加并被数字化以提取定时和能量信息。延迟和通道包括在每个传感器之后引入已知延迟的离散延迟线，为传感器创建时间签名，之后是加上延迟信号的求和电路。延迟和通道使用高速计数器进行数字化，以提取位置信息。当和通道输出和延迟和通道输出分别跨越脉冲ID阈值时，导出计数器的启动和停止信号。选择脉冲ID阈值以最小化康普顿散射，而不剪切光峰事件。

5. 发明授权

US08633444B2 Efficient and serviceable light guide for PET detector 有权
公开(公告)号：US08633444B2
公开(公告)日：2014-01-21
申请号：US13153021
申请日：2011-06-03
申请人： Kent C. Burr , Daniel Gagnon , Zhengyan Wang
发明人： Kent C. Burr , Daniel Gagnon , Zhengyan Wang
IPC分类号： G01T1/164
CPC分类号： G01T1/2985 , G01T1/1644 , H01L31/02325
摘要： A positron emission tomography (PET) detector module includes an array of scintillation crystal elements and a plurality of photosensors arranged to at least partially cover the array of scintillation crystal elements. The photosensors are configured to receive light emitted from the array of scintillation crystal elements. The module includes a transparent adhesive arranged between the array of scintillation crystal elements and the plurality of photosensors. The transparent adhesive extends directly from a surface of at least one of the scintillation crystal elements to a surface of at least one of the photosensors and is configured to distribute the light emitted from one of the scintillation crystal elements to more than one of the photosensors. A method of manufacturing the module includes various steps utilizing a fixture. A PET scanner uses multiple modules arranged circumferentially around an area to be scanned.

6. 发明授权

US08611628B2 Using non-attenuation corrected PET emission images to compensate for incomplete anatomic images 有权
标题翻译：使用非衰减校正PET发射图像补偿不完全的解剖图像
公开(公告)号：US08611628B2
公开(公告)日：2013-12-17
申请号：US12990285
申请日：2009-05-04
申请人： Zhiqiang Hu , Daniel Gagnon , Chi-Hua Tung
发明人： Zhiqiang Hu , Daniel Gagnon , Chi-Hua Tung
IPC分类号： G06K9/00
CPC分类号： G06T11/006 , G06T2211/424 , G06T2211/432
摘要： When compensating for truncated patient scan data acquired by a multi-modal PET/CT or PET/MR imaging system (14, 16), such as occurs when a patient is larger than a field of view for an anatomical imaging device, a segmented contour of a non-attenuation-corrected (NAC) PET image is used to identify a contour of the truncated region. An appropriate tissue type is used to fill in truncated regions of a truncated CT or MR image for the attenuation map. The corrected attenuation map is then used to generate an attenuation-corrected PET image of the patient or a region of interest. Alternatively, the system can be employed in PET/CT or PET/MR imaging scenarios where two modalities are performed sequentially (e.g., not simultaneously), and thus the contour derived from the PET scan can be compared to the CT or MR image to infer potential subject motion between the PET and CT or MR scans. Additionally, the system can be employed in PET imaging scenarios where the contour derived from the NAC PET image is used as emission boundary for scatter correction using single-scatter simulation, in which a tail-fitting procedure utilizes an emission boundary to define pure-scatter tails (e.g., in the absence of true coincidence events).
摘要翻译：当补偿由多模式PET / CT或PET / MR成像系统（14,16）获取的截断的患者扫描数据时，例如当患者大于解剖成像装置的视野时发生，分割的轮廓使用非衰减校正（NAC）PET图像来识别截断区域的轮廓。使用适当的组织类型来填充用于衰减图的截断的CT或MR图像的截断区域。然后校正的衰减图用于产生患者或感兴趣区域的衰减校正的PET图像。或者，该系统可以用于PET / CT或PET / MR成像场合，其中顺序执行两种模式（例如，不同时执行），因此可以将从PET扫描导出的轮廓与CT或MR图像进行比较以推断 PET和CT或MR扫描之间的潜在主体运动。此外，该系统可以用于PET成像场景，其中从NAC PET图像导出的轮廓用作使用单分散模拟的散射校正的发射边界，其中尾部拟合过程利用发射边界来定义纯散射尾巴（例如，没有真正的巧合事件）。

7. 发明授权

US08488849B2 Image reconstruction using data ordering 有权
标题翻译：使用数据排序的图像重建
公开(公告)号：US08488849B2
公开(公告)日：2013-07-16
申请号：US12279848
申请日：2007-02-05
申请人： Zhiqiang Hu , Wenli Wang , Daniel Gagnon
发明人： Zhiqiang Hu , Wenli Wang , Daniel Gagnon
IPC分类号： G06K9/00
CPC分类号： G06K9/00362 , G06T11/006
摘要： Methods, systems and apparatuses for processing data associated with nuclear medical imaging techniques are provided. Data is ordered in LUT's and memory structures. Articles of manufacture are provided for causing computers to carry out aspects of the invention. Data elements are ordered into a plurality of ordered data groups according to a spatial index order, and fetched and processed in the spatial index order. The data elements include sensitivity matrix elements, PET annihilation event data, and system and image matrix elements, the data grouped in orders corresponding to their processing. In one aspect geometric symmetry of a PET scanner FOV is used in ordering the data and processing. In one aspect a system matrix LUT comprises total number of system matrix elements equal to a total number of image matrix elements divided by a total number of possible third index values.
摘要翻译：提供了用于处理与核医学成像技术有关的数据的方法，系统和装置。数据按照LUT和内存结构进行排序。提供制造用于使计算机执行本发明的方面。数据元素根据空间索引顺序排列成多个有序数据组，并以空间索引顺序取出并处理。数据元素包括灵敏度矩阵元素，PET湮灭事件数据，以及系统和图像矩阵元素，数据按照与其处理相对应的顺序分组。在一个方面，PET扫描器FOV的几何对称性用于排序数据和处理。在一个方面，系统矩阵LUT包括等于图像矩阵元素的总数除以可能的第三索引值的总数的系统矩阵元素的总数。

8. 发明授权

US08437836B2 Reverse data reconstruction for optimal time sampling of counts in physiological list-mode nuclear imaging 有权
标题翻译：反向数据重建，用于生理列表模式核成像中计数的最佳时间采样
公开(公告)号：US08437836B2
公开(公告)日：2013-05-07
申请号：US12995685
申请日：2009-05-29
申请人： Daniel Gagnon , Sameer Tipnis , Raymond Muzic
发明人： Daniel Gagnon , Sameer Tipnis , Raymond Muzic
IPC分类号： A61B6/00
CPC分类号： A61B6/507 , A61B6/037 , A61B6/486 , G06T11/006 , G06T2211/412
摘要： A diagnostic imaging device includes detector elements (16) for detecting y-rays indicative of nuclear decay events. Pairs of concurrently detected γ-rays define lines of response (LORs) which are collected, time stamped, and compiled in list-mode. In tissue perfusion studies, it is beneficial to use the data that concurrently maximizes contrast and signal-to-noise ratio in the reconstructed images. Using the list-mode data, events in an adjustable temporal window (33) are reconstructed and the reconstructed images are analyzed to determine a figure of merit based on contrast and signal-to-noise properties of the image. By iteratively adjusting the temporal window, extending its start point (36) backwards in time, and repeating the reconstructing, analyzing, and adjusting steps, an image with an optimal figure of merit is obtained.
摘要翻译：诊断成像装置包括用于检测表示核衰变事件的y射线的检测器元件（16）。同时检测到的伽马射线的对确定了收集的行（LOR），并以列表模式进行时间戳和编译。在组织灌注研究中，使用同时最大化重建图像中的对比度和信噪比的数据是有益的。使用列表模式数据，重建可调节时间窗口（33）中的事件，并且分析重建图像以基于图像的对比度和信噪比特性确定品质因数。通过迭代调整时间窗口，及时地将其起点（36）向后延伸，并重复重建，分析和调整步骤，获得具有最佳品质因数的图像。

9. 发明申请

US20120305783A1 PHOTOMULTIPLIER TUBE WITH INTEGRATED FAST ANALOG-TO-DIGITAL CONVERSION FOR EVENT DERANDOMIZER AND DIGITAL TIME STAMPING 有权
标题翻译：具有一体化快速模拟数字转换功能的光电管和数字时间戳
公开(公告)号：US20120305783A1
公开(公告)日：2012-12-06
申请号：US13153611
申请日：2011-06-06
申请人： Daniel GAGNON , Kent Burr
发明人： Daniel GAGNON , Kent Burr
IPC分类号： G01T1/16 , H03F3/08
CPC分类号： G01T1/1647
摘要： A digital photosensor that includes a photomultiplier tube (PMT) including a power distribution circuit, the PMT outputting an analog signal in response to received light; an analog-to-digital converter (ADC) to receive the analog signal and to generate a digital signal; and a non-transitory memory storing manufacturing parameters of the PMT and operational parameters of the PMT, the operational parameters being calculated by a parameter calculation unit during operation of the PMT, wherein the PMT, the ADC, and the memory are integrated into a single housing
摘要翻译：一种数字光电传感器，包括具有功率分配电路的光电倍增管（PMT），所述PMT响应于所接收的光而输出模拟信号; 模数转换器（ADC），用于接收模拟信号并产生数字信号; 以及存储PMT的制造参数和PMT的运行参数的非暂时性存储器，所述运行参数由PMT运转中的参数运算单元计算，其中所述PMT，所述ADC和所述存储器被集成为单个住房

10. 发明申请

US20120271164A1 METHOD AND SYSTEM FOR ORGAN SPECIFIC PET IMAGING 有权
标题翻译：用于组织特异性PET成像的方法和系统
公开(公告)号：US20120271164A1
公开(公告)日：2012-10-25
申请号：US13091746
申请日：2011-04-21
申请人： Daniel GAGNON
发明人： Daniel GAGNON
IPC分类号： A61B6/00
CPC分类号： G01T1/2985 , A61B6/037
摘要： An imaging system, including (1) a CT scanner configured to scan an object arranged on a patient pallet; (2) a PET scanner, including a first detector portion, including first detector elements, arranged circumferentially around the patient pallet, the first detector portion having a predetermined axial extent and transaxially subtending less than 360 degrees with respect to a central axis of the scanner; and a second detector portion, including second detector elements, arranged separately from and opposing the first detector portion, wherein the second detector elements are of a different type than the first detector elements, and the second detector portion is configured to be movable radially and circumferentially around the object; and (3) an acquisition subsystem configured to acquire first event data from the first detector portion and to acquire second event data from the second detector portion.
摘要翻译：一种成像系统，包括（1）CT扫描器，其构造成扫描布置在患者托盘上的物体; （2）一种PET扫描器，包括第一检测器部分，其包括围绕病人托盘周向布置的第一检测器元件，第一检测器部分具有预定的轴向范围，并相对于扫描仪的中心轴轴向对着小于360度 ; 以及第二检测器部分，包括与第一检测器部分分开设置并与第一检测器部分相对布置的第二检测器元件，其中第二检测器元件具有与第一检测器元件不同的类型，并且第二检测器部分被配置为可径向地和周向地移动围绕物体; 以及（3）采集子系统，被配置为从所述第一检测器部分获取第一事件数据并且从所述第二检测器部分获取第二事件数据。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式