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1. 发明申请

US20120136196A1 MOBILE IMAGING UNIT WITH ENVIRONMENTAL CONTAINMENT 审中-公开
标题翻译：具有环境容量的移动成像单元
公开(公告)号：US20120136196A1
公开(公告)日：2012-05-31
申请号：US13322577
申请日：2010-05-12
申请人： David L. Foxall , Daniel Lamb
发明人： David L. Foxall , Daniel Lamb
IPC分类号： A61G10/00 , G01R33/44 , H01J37/20 , G06K9/00
CPC分类号： G01R33/383 , A61B5/055 , A61B6/032 , A61B6/04 , A61B6/0442 , A61B6/10 , A61B6/4028 , A61B6/4405 , A61B6/4423 , A61B6/4429 , A61B6/4476 , A61B6/488 , A61G3/001 , G01R33/3802 , G01R33/3806
摘要： A system comprises: an isolation tube (42, 82) extending into a clean area (14), the isolation tube having a closed end (44) and an opposite open end (46) that is open to a contamination area (12) adjacent the clean area in order to receive an imaging subject from the contamination area; and an imaging apparatus (40, 80) disposed in the clean area and movable along the isolation tube in order to image a subject in the isolation tube at a plurality of different positions along the isolation tube. In some more specific embodiments, the system further includes a vehicle (10) having an interior including the contamination area (12) and the adjacent clean area (14) wherein the system is a mobile imaging unit.
摘要翻译：一种系统包括：隔离管（42,82），其延伸到清洁区域（14）中，所述隔离管具有封闭端（44）和相对的开放端（46），所述封闭端（44）和邻近的污染区域清洁区域以便从污染区域接收成像对象; 以及设置在清洁区域中并可沿着隔离管移动的成像装置（40,80），以便沿着隔离管在多个不同位置对隔离管中的对象成像。在一些更具体的实施例中，系统还包括具有包括污染区域（12）和相邻清洁区域（14）的内部的车辆（10），其中系统是移动成像单元。

2. 发明授权

US07646199B2 Integrated system of MRI RF loop coils plus spacing fixtures with biocontainment uses 失效
标题翻译： MRI射频回路线圈集成系统以及具有生物识别用途的间距夹具
公开(公告)号：US07646199B2
公开(公告)日：2010-01-12
申请号：US11845827
申请日：2007-08-28
申请人： Wayne R. Dannels , Chun Jiang Xiao , Robert C. Gauss , John T. Carlon , David L. Foxall
发明人： Wayne R. Dannels , Chun Jiang Xiao , Robert C. Gauss , John T. Carlon , David L. Foxall
IPC分类号： G01V3/00 , A61B5/055
CPC分类号： G01R33/3415 , G01R33/34007 , G01R33/34084 , G01R33/3621
摘要： When scanning a patient to generate an image thereof, radio frequency (RF) coil modules are scalably coupled to each other using a plurality of clips to form flat or polygonal coil arrays that are placed on or around the patient or a portion thereof. A user assesses the volume to be imaged, identifies a coil array configuration of suitable size and shape and employs clips of one or more pre-determined angles to construct the identified coil array configuration, which is placed on or about the volume. Coil modules are coupled to a preamplifier interface box (PIB), which provides preamplified coil signal(s) to a patient imaging device, such as an MRI scanner. Small arrays are constructible to accommodate pediatric patients and/or smaller animals. Modules are hermetically sealed, can be sanitized between uses, and discarded at end-of-life. In one aspect, the modular coil array, clips, and PIB are maintained in an isolated contamination zone, separate from the patient imaging device.
摘要翻译：当扫描患者以产生其图像时，射频（RF）线圈模块可以使用多个夹子彼此可伸缩地联接，以形成放置在患者或其一部分上或周围的平面或多边形线圈阵列。用户评估要成像的体积，识别适当尺寸和形状的线圈阵列配置，并且使用一个或多个预定角度的夹子来构造放置在卷上或周围的所识别的线圈阵列配置。线圈模块耦合到前置放大器接口盒（PIB），其将前置放大的线圈信号提供给诸如MRI扫描仪的患者成像装置。小阵列是可构建的，以适应儿科患者和/或较小的动物。模块密封，可在使用之间进行消毒，并在生命周期中丢弃。在一个方面，模块化线圈阵列，夹子和PIB保持在与患者成像装置分开的隔离污染区域中。

3. 发明授权

US06624630B1 Sliding frequency steady-state precession imaging 失效
标题翻译：滑动频率稳态进动成像
公开(公告)号：US06624630B1
公开(公告)日：2003-09-23
申请号：US09989818
申请日：2001-11-20
申请人： David L. Foxall
发明人： David L. Foxall
IPC分类号： G01V300
CPC分类号： G01R33/5613 , G01R33/56554
摘要： A steady-state free precession (SSFP) sequence includes a large multiplicity of RF pulses (40) with a relatively short repeat time or interpulse interval (TR) on the order of 2-10 milliseconds. After applying the RF pulses for a period of about 3 T1, about 6 seconds, a steady-state is achieved. Thereafter, at least a phase-encode gradient (42) and a read gradient (44) are applied between each subsequent pair of adjoining RF pulses, a data line being generated during each read gradient pulse. For a 128 line image with a TR of 6 milliseconds, a set of data lines are generated in 768 milliseconds, about ¾ of a second. As the data lines are generated, a spectral offset is adjusted by continuously adjusting an RF phase of an RF transmitter (24) and an RF receiver (50), with N sets of data lines being generated over 360° of RF phase shift. Like corresponding data lines from each set offset an RF phase by 360°/N are combined and Fourier transformed into an image representation. In this manner, N complete data sets are collected at different spectral offsets without intervening delay intervals to reestablish the steady-state, i.e., in 9 seconds instead of 27 seconds (for N=4).
摘要翻译：稳态自由进动（SSFP）序列包括具有2-10毫秒量级的较短重复时间或脉冲间隔（TR）的大量RF脉冲（40）。在大约3T1周期的RF脉冲施加约6秒之后，实现稳态。此后，在每个后续的一对相邻的RF脉冲之间至少施加相位编码梯度（42）和读取梯度（44），在每个读取梯度脉冲期间产生数据线。对于TR为6毫秒的128行图像，在768毫秒内产生大约3/4秒的数据线。当生成数据线时，通过连续调整RF发射器（24）和RF接收器（50）的RF相位来调整频谱偏移，其中N组数据线在RF相移360°以上产生。像来自每一组的相应的数据线偏移360°/ N的RF相位被组合并且被傅立叶变换成图像表示。以这种方式，N个完整数据集在不同的频谱偏移处被收集，没有中间延迟时间间隔来重新建立稳态，即在9秒而不是27秒（对于N = 4）。

4. 发明授权

US06249595B1 Iterative reconstruction for EPI 失效
标题翻译： EPI的迭代重建
公开(公告)号：US06249595B1
公开(公告)日：2001-06-19
申请号：US09131905
申请日：1998-08-10
申请人： David L. Foxall , Paul R. Harvey , Jian Huang
发明人： David L. Foxall , Paul R. Harvey , Jian Huang
IPC分类号： G06K900
CPC分类号： G06T11/006 , G01R33/56545 , G01R33/56554 , G06T2211/424
摘要： A method of iterative reconstruction for MRI imaging, comprising: (a) acquiring data into a k-space, wherein some of said data is acquired using an opposite gradient polarity from other of said data; (b) partially reconstructing at least a portion of the data, using a Fourier transform; (c) test reconstructing, at least a portion of an image, from the partially reconstructed data, using a set of reconstruction parameters, comprising at least one reconstruction parameter; (d) measuring an image quality measure of the test reconstructed image; and (e) automatically repeating (c) and (d) for a plurality of sets of reconstruction parameters to determine an acceptable reconstructed image, using the same partially reconstructed data.
摘要翻译：一种用于MRI成像的迭代重建方法，包括：（a）将数据采集到k空间中，其中使用与所述其他数据相反的梯度极性获取所述数据中的一些; （b）使用傅立叶变换来部分地重构所述数据的至少一部分; （c）使用包括至少一个重建参数的一组重建参数来测试来自所述部分重建的数据的图像的至少一部分; （d）测量测试重建图像的图像质量测量; 以及（e）使用相同的部分重建的数据自动重复（c）和（d）多个重建参数组以确定可接受的重建图像。

5. 发明授权

US4777441A Rotating frame zeugmatography 失效
标题翻译：旋转框架色谱
公开(公告)号：US4777441A
公开(公告)日：1988-10-11
申请号：US29281
申请日：1987-03-23
申请人： David L. Foxall
发明人： David L. Foxall
IPC分类号： A61B10/00 , A61B5/055 , G01R33/48 , G01R33/20
CPC分类号： G01R33/445
摘要： A set of n NMR measurements are carried out in an inhomogeneous RF field. The set is parameterized by RF pulse amplitude or duration and for half the measurements the variation of RF pulse/duration is reversed and the RF phase inverted.

6. 发明申请

US20090096449A1 LOW POWER BROADBAND SPIN DECOUPLING 失效
标题翻译：低功率宽带旋转解除
公开(公告)号：US20090096449A1
公开(公告)日：2009-04-16
申请号：US12295942
申请日：2007-03-16
申请人： David L. Foxall
发明人： David L. Foxall
IPC分类号： G01R33/54
CPC分类号： G01R33/4616
摘要： In a magnetic resonance data acquisition method, magnetic resonance is excited (72, 74) in an observed nuclear species. Magnetic resonance data of the observed nuclear species are acquired (76). A plurality of different broadband decoupling radio frequency pulses (80) configured to decouple a coupled nuclear species from the observed nuclear species are applied. Each broadband decoupling radio frequency pulse has a different or randomized or pseudorandomized amplitude (110) as a function of time. Each broadband decoupling radio frequency pulse has about the same peak power, pulse duration, and frequency spread. The differences between the broadband decoupling radio frequency pulses are effective to substantially suppress cycling sidebands.
摘要翻译：在磁共振数据采集方法中，在观察到的核物种中磁共振被激发（72,74）。获得观察到的核物种的磁共振数据（76）。应用多个不同的宽带去耦射频脉冲（80），其被配置为将耦合的核物质与观察到的核物种分离。每个宽带去耦射频脉冲具有与时间有关的不同的或随机的或伪随机的幅度（110）。每个宽带去耦射频脉冲具有大致相同的峰值功率，脉冲持续时间和频率扩展。宽带去耦射频脉冲之间的差异对于基本上抑制循环边带是有效的。

7. 发明授权

US07235971B2 Shimming of MRI scanner involving fat suppression and/or black blood preparation 失效
标题翻译：涉及脂肪抑制和/或黑血液制备的MRI扫描仪的匀场
公开(公告)号：US07235971B2
公开(公告)日：2007-06-26
申请号：US10564048
申请日：2004-07-07
申请人： David L. Foxall , Wim M. Prins
发明人： David L. Foxall , Wim M. Prins
IPC分类号： G01V3/00
CPC分类号： G01R33/3875
摘要： In a method for shimming a magnetic resonance imaging scanner (10), at least one of fat suppression and blood suppression is performed to suppress magnetic resonance from a corresponding at least one of fat and blood. First and second magnetic resonance echoes emanating from a generally columnar volume are measured. The measurements of the first and second magnetic resonance echoes (122, 124) are reconstructed (150) into corresponding first and second generally columnar projection images (152, 154). The first and second generally columnar projection images are combined (160) to produce a magnetic field profile (174) of the generally columnar volume. Selected magnetic field parameters are extracted (142) from the magnetic field profile. Shim currents are computed (180) from the selected magnetic field parameters. The shim currents are applied to magnetic field coils (16, 60).
摘要翻译：在用于对磁共振成像扫描仪（10）进行匀场的方法中，进行脂肪抑制和血液抑制中的至少一种以抑制来自相应的脂肪和血液中的至少一种的磁共振。测量从大体积柱体积发出的第一和第二磁共振回波。第一和第二磁共振回波（122,124）的测量被重建（150）到对应的第一和第二大体柱形投影图像（152,154）中。第一和第二大体上柱状投影图像被组合（160）以产生大体积柱体积的磁场分布（174）。选择的磁场参数从磁场分布提取（142）。从选定的磁场参数计算（180）Shim电流。垫片电流施加到磁场线圈（16,60）。

8. 发明授权

US06516210B1 Signal analysis for navigated magnetic resonance imaging 失效
标题翻译：导航磁共振成像的信号分析
公开(公告)号：US06516210B1
公开(公告)日：2003-02-04
申请号：US09718728
申请日：2000-11-22
申请人： David L. Foxall
发明人： David L. Foxall
IPC分类号： A61B505
CPC分类号： G01R33/5676
摘要： A method of imaging a patient with an MRI scanner (10) includes imaging a region of interest of the patient with the MRI scanner (10) and acquiring image data resulting from the imaging. An image of the region of interest is reconstructed from the image data. The method also includes generating navigator echos during the imaging, collecting the navigator echos and deriving, from each navigator echo, a measurement of patient motion experience during the imaging. A historical record of the measurements is maintained. Parameters for the acquisition of image data are selected to compensate for motion, or specific image data is selected for reconstruction, based on the historical record.
摘要翻译：利用MRI扫描仪（10）对患者进行成像的方法包括用MRI扫描器（10）对患者的感兴趣区域成像并获取由成像产生的图像数据。从图像数据重建感兴趣区域的图像。该方法还包括在成像期间产生导航器回波，收集导航器回波并从每个导航器回波导出在成像期间的患者运动体验的测量。保持测量的历史记录。选择用于获取图像数据的参数以补偿运动，或者基于历史记录选择特定图像数据进行重建。

9. 发明授权

US07948235B2 Low power broadband spin decoupling 失效
标题翻译：低功率宽带自旋去耦
公开(公告)号：US07948235B2
公开(公告)日：2011-05-24
申请号：US12295942
申请日：2007-03-16
申请人： David L. Foxall
发明人： David L. Foxall
IPC分类号： G01V3/00
CPC分类号： G01R33/4616
摘要： In a magnetic resonance data acquisition method, magnetic resonance is excited (72, 74) in an observed nuclear species. Magnetic resonance data of the observed nuclear species are acquired (76). A plurality of different broadband decoupling radio frequency pulses (80) configured to decouple a coupled nuclear species from the observed nuclear species are applied. Each broadband decoupling radio frequency pulse has a different or randomized or pseudorandomized amplitude (110) as a function of time. Each broadband decoupling radio frequency pulse has about the same peak power, pulse duration, and frequency spread. The differences between the broadband decoupling radio frequency pulses are effective to substantially suppress cycling sidebands.
摘要翻译：在磁共振数据采集方法中，在观察到的核物种中磁共振被激发（72,74）。获得观察到的核物种的磁共振数据（76）。应用多个不同的宽带去耦射频脉冲（80），其被配置为将耦合的核物质与观察到的核物种分离。每个宽带去耦射频脉冲具有与时间有关的不同的或随机的或伪随机的幅度（110）。每个宽带去耦射频脉冲具有大致相同的峰值功率，脉冲持续时间和频率扩展。宽带解耦射频脉冲之间的差异对于基本上抑制循环边带是有效的。

10. 发明申请

US20080211498A1 INTEGRATED SYSTEM OF MRI RF LOOP COILS PLUS SPACING FIXTURES WITH BIOCONTAINMENT USES 失效
标题翻译： MRI RF环绕线圈集成系统采用生物化学用途加上间距
公开(公告)号：US20080211498A1
公开(公告)日：2008-09-04
申请号：US11845827
申请日：2007-08-28
申请人： Wayne R. Dannels , Chun Jiang Xiao , Robert C. Gauss , John T. Carlon , David L. Foxall
发明人： Wayne R. Dannels , Chun Jiang Xiao , Robert C. Gauss , John T. Carlon , David L. Foxall
IPC分类号： G01R33/32 , G01R33/483
CPC分类号： G01R33/3415 , G01R33/34007 , G01R33/34084 , G01R33/3621
摘要： When scanning a patient to generate an image thereof, radio frequency (RF) coil modules are scalably coupled to each other using a plurality of clips to form flat or polygonal coil arrays that are placed on or around the patient or a portion thereof. A user assesses the volume to be imaged, identifies a coil array configuration of suitable size and shape and employs clips of one or more pre-determined angles to construct the identified coil array configuration, which is placed on or about the volume. Coil modules are coupled to a preamplifier interface box (PIB), which provides preamplified coil signal(s) to a patient imaging device, such as an MRI scanner. Small arrays are constructible to accommodate pediatric patients and/or smaller animals. Modules are hermetically sealed, can be sanitized between uses, and discarded at end-of-life. In one aspect, the modular coil array, clips, and PIB are maintained in an isolated contamination zone, separate from the patient imaging device.
摘要翻译：当扫描患者以产生其图像时，射频（RF）线圈模块可以使用多个夹子彼此可伸缩地联接，以形成放置在患者或其一部分上或周围的平面或多边形线圈阵列。用户评估要成像的体积，识别适当尺寸和形状的线圈阵列配置，并且使用一个或多个预定角度的夹子来构造放置在卷上或周围的所识别的线圈阵列配置。线圈模块耦合到前置放大器接口盒（PIB），其将前置放大的线圈信号提供给诸如MRI扫描仪的患者成像装置。小阵列是可构建的，以适应儿科患者和/或较小的动物。模块密封，可在使用之间进行消毒，并在生命周期中丢弃。在一个方面，模块化线圈阵列，夹子和PIB保持在与患者成像装置分开的隔离污染区域中。

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