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1. 发明授权

US09560990B2 Obtaining baseline patient information 有权
标题翻译：获取基线患者信息
公开(公告)号：US09560990B2
公开(公告)日：2017-02-07
申请号：US13544222
申请日：2012-07-09
申请人： Dennis M. Skelton , Jon P. Davis , Dennis Bourget
发明人： Dennis M. Skelton , Jon P. Davis , Dennis Bourget
IPC分类号： A61B5/00 , A61M25/00 , A61M25/09 , A61B5/05 , A61B5/11 , A61N1/372 , A61N1/05 , A61N1/36 , A61N1/365
CPC分类号： A61B5/1116 , A61B5/0031 , A61B5/1118 , A61B5/4815 , A61B5/6846 , A61B5/686 , A61B2560/0219 , A61N1/0551 , A61N1/36071 , A61N1/36078 , A61N1/36085 , A61N1/36107 , A61N1/36132 , A61N1/36535 , A61N1/37247 , A61N1/37282 , G06F19/00
摘要： The disclosure relates to a method and system for obtaining baseline patient information. In some examples, a method may include acquiring first patient data, wherein the first patient data comprises at least one of first posture state data indicative of a plurality of posture states of a patient during a first time period or first therapy adjustment data indicative of a plurality of patient therapy adjustments made during the first time period; generating baseline patient information based at least in part on the first patient data; and comparing the baseline patient information to patient information generated based on second patient data. Therapy is not delivered to the patient according to a detected posture state of the patient during the first time period, and therapy is delivered to the patient according to the detected posture state of the patient during the second time period.
摘要翻译：本公开涉及一种用于获得基线患者信息的方法和系统。在一些示例中，方法可以包括获取第一患者数据，其中第一患者数据包括指示患者在第一时间段期间的多个姿势状态的第一姿势状态数据或指示患者的第一治疗调整数据中的至少一个在第一时期进行多次病人治疗调整; 至少部分地基于所述第一患者数据生成基线患者信息; 以及将基线患者信息与基于第二患者数据生成的患者信息进行比较。根据在第一时间段期间患者的检测到的姿势状态，不向患者传递治疗，并且根据在第二时间段期间检测到的患者的姿势状态将治疗递送给患者。

2. 发明授权

US09440084B2 Programming posture responsive therapy 有权
标题翻译：编程姿势反应疗法
公开(公告)号：US09440084B2
公开(公告)日：2016-09-13
申请号：US12433551
申请日：2009-04-30
申请人： Jon P. Davis , Dennis M. Skelton , Shyam Gokaldas , Rajeev Sahasrabudhe
发明人： Jon P. Davis , Dennis M. Skelton , Shyam Gokaldas , Rajeev Sahasrabudhe
IPC分类号： A61N1/36 , A61N1/372 , G06F19/00 , A61B5/11 , A61N1/365
CPC分类号： A61N1/37247 , A61B5/1116 , A61B5/1118 , A61B2562/0219 , A61N1/36071 , A61N1/36132 , A61N1/36135 , A61N1/36542 , G06F19/00 , G06F19/3418 , G06F19/3481 , G16H20/10 , G16H40/63 , G16H50/20 , G16H80/00
摘要： A programming session for an implantable medical device that includes a posture responsive therapy mode includes at least two phases. In a first phase, a first set of therapy parameter values are modified while the posture responsive therapy mode is deactivated. In the posture responsive therapy mode, the medical device automatically selects one or more therapy parameter values that define therapy delivered to a patient based on a detected posture state. In a second phase, the posture responsive therapy mode is activated and a second set of therapy parameter values are adjusted after observing a patient response to the posture responsive therapy delivered with the first set of therapy parameter values selected during the first phase. The second set of therapy parameter values may, for example, define the patient posture states or the modification profiles with which the medical device adjusts therapy upon detecting a posture state transition.
摘要翻译：包括姿势响应治疗模式的可植入医疗装置的编程会话包括至少两个阶段。在第一阶段中，在停止姿势响应治疗模式的同时修改第一组治疗参数值。在姿势响应治疗模式中，医疗装置基于检测到的姿势状态自动选择定义治疗被传递给患者的治疗参数值。在第二阶段中，激活姿势响应治疗模式，并且在观察患者对在第一阶段期间选择的第一组治疗参数值递送的姿势响应治疗的响应之后，调整第二组治疗参数值。第二组治疗参数值可以例如定义患者姿势状态或修改简档，医疗装置在检测姿势状态转换时通过该修改简档来调整治疗。

3. 发明授权

US09327070B2 Medical device therapy based on posture and timing 有权
标题翻译：基于姿势和时机的医疗器械治疗
公开(公告)号：US09327070B2
公开(公告)日：2016-05-03
申请号：US12433501
申请日：2009-04-30
申请人： Dennis M. Skelton , Jon P. Davis , Timothy J. Denison
发明人： Dennis M. Skelton , Jon P. Davis , Timothy J. Denison
IPC分类号： A61M5/142 , A61B5/00 , A61B5/11 , A61N1/36 , A61N1/372
CPC分类号： A61M5/14276 , A61B5/11 , A61B5/1116 , A61B5/7475 , A61B2562/0219 , A61M2005/14208 , A61M2210/0693 , A61M2210/1053 , A61M2210/1078 , A61M2230/62 , A61N1/36071 , A61N1/36139 , A61N1/37247
摘要： This disclosure describes techniques implemented by a medical device, such as an implantable medical device (IMD). The IMD may be configured to detect a posture state of a patient, and deliver posture-responsive therapy. In particular, the IMD not only detects the posture state of a patient, but also detects timing associated with the detected posture state, such as the time of day, the day of the week, or a specific time of day associated with a specific day. In this way, the posture-responsive therapy delivered by the IMD may be dependent not only on the posture state of the patient, but also on the timing associated with the posture state. The same posture state, therefore, may result in different types of therapy to the patient if the same posture occurs at different times of the day.
摘要翻译：本公开描述了由诸如可植入医疗装置（IMD）的医疗装置实现的技术。 IMD可以被配置为检测患者的姿势状态，并且提供姿势响应治疗。特别地，IMD不仅检测患者的姿势状态，而且检测与检测到的姿势状态相关联的定时，例如一天中的时间，一周中的一天或与特定日期相关联的特定时间。以这种方式，由IMD递送的姿势响应治疗不仅取决于患者的姿势状态，而且还取决于与姿势状态相关的时间。因此，如果在一天的不同时间发生相同的姿势，那么相同的姿势状态可能导致对患者的不同类型的治疗。

4. 发明授权

US08751011B2 Defining therapy parameter values for posture states 有权
标题翻译：定义姿势状态的治疗参数值
公开(公告)号：US08751011B2
公开(公告)日：2014-06-10
申请号：US12433854
申请日：2009-04-30
申请人： Dennis M. Skelton , Jon P. Davis , Joseph J. Nolan , Rajeev Sahasrabudhe , Shyam Gokaldas
发明人： Dennis M. Skelton , Jon P. Davis , Joseph J. Nolan , Rajeev Sahasrabudhe , Shyam Gokaldas
IPC分类号： A61N1/00
CPC分类号： A61N1/36135 , A61B5/1116 , A61B5/686 , A61B5/7435 , A61B2560/0219 , A61B2562/0219 , A61N1/36535 , A61N1/36542 , G06F19/00 , G06F19/3418 , G16H10/60 , G16H40/63 , G16H40/67 , G16H50/20
摘要： The disclosure is directed towards posture-responsive therapy. To avoid interruptions in effective therapy, an implantable medical device may include a posture state module that detects the posture state of the patient and automatically adjusts therapy parameter values according to the detected posture state. A system may include an external programmer comprising a user interface that receives user input defining therapy parameter values for delivery of therapy to a patient, and user input associating one or more of the therapy parameter values with a plurality of posture states based on user input, a processor that automatically defines therapy parameter values for delivery of therapy to a patient when the patient occupies the posture states based on the association, and an implantable medical device that delivers the therapy to the patient in response to detection of the posture states.
摘要翻译：本公开涉及姿势响应疗法。为了避免有效治疗中断，可植入医疗装置可以包括检测患者的姿势状态的姿势状态模块，并且根据检测到的姿势状态自动调整治疗参数值。系统可以包括外部编程器，其包括用户接口，用户接口定义用于向患者传递治疗的治疗参数值的用户输入，以及基于用户输入将治疗参数值中的一个或多个与多个姿势状态相关联的用户输入，处理器，当处于基于关联的患者占据姿势状态时，自动地定义用于将治疗递送到患者的治疗参数值;以及可植入医疗装置，其响应于姿势状态的检测将治疗递送给患者。

5. 发明授权

US08688225B2 Posture state detection using selectable system control parameters 有权
标题翻译：姿态检测采用可选择的系统控制参数
公开(公告)号：US08688225B2
公开(公告)日：2014-04-01
申请号：US12433029
申请日：2009-04-30
申请人： Eric J. Panken , Dennis M. Skelton
发明人： Eric J. Panken , Dennis M. Skelton
IPC分类号： A61N1/00
CPC分类号： A61N1/36542 , A61B5/1116 , A61B5/1118 , A61B5/686 , A61B5/7264 , A61B2562/0219 , A61N1/36535 , G06F19/00
摘要： Techniques for detecting and classifying a posture state of a patient are disclosed, wherein a posture state includes at least one of a posture and/or an activity state related to motion. In one embodiment, one or more signals indicative of at least one of posture and activity state of the patient may be sensed by a sensor. Control logic may be provided to process the one or more sensed signals in a selectable manner. This selectable manner may be based on current posture state data describing a posture state in which the patient has previously been classified. Alternatively or additionally, this current posture state data may describe a posture state transition previously undergone by the patient. The one or more signals that are so processed may then be used to classify a posture state of the patient.
摘要翻译：公开了用于检测和分类患者的姿势状态的技术，其中姿势状态包括与运动相关的姿势和/或活动状态中的至少一个。在一个实施例中，可以由传感器感测指示患者的姿势和活动状态中的至少一个的一个或多个信号。可以提供控制逻辑以以可选择的方式处理一个或多个感测信号。该可选择方式可以基于描述患者以前被分类的姿势状态的当前姿势状态数据。或者或另外，该当前姿势状态数据可以描述先前由患者进行的姿势状态转换。然后可以将如此处理的一个或多个信号用于对患者的姿势状态进行分类。

6. 发明申请

US20130274830A1 VELOCITY DETECTION FOR POSTURE-RESPONSIVE THERAPY 有权
标题翻译：快速感应治疗的速度检测
公开(公告)号：US20130274830A1
公开(公告)日：2013-10-17
申请号：US13445506
申请日：2012-04-12
申请人： Dennis M. Skelton
发明人： Dennis M. Skelton
IPC分类号： A61N1/36
CPC分类号： A61N1/36128 , A61N1/3605
摘要： The disclosure describes techniques for modifying an electrical stimulation or another type of therapy provided to a patient by a medical device. The therapy modification may be based on a posture and/or activity state of a patient that is detected by an IMD, such as a change in a detected posture state occupied by the patient. Different therapy modifications may be applied for different changes in detected posture state. An IMD may modify therapy based on a transition from one posture state to another posture state. The IMD may determine a posture state of the patient for use in controlling therapy adjustments and/or other aspects of the system. In some examples, when the patient's movement and/or activity velocity exceeds a velocity threshold, a previously-determined stable posture state of the patient may be used to control therapy rather than a current posture state of the patient, which may be transient.
摘要翻译：本公开描述了用于修改由医疗装置提供给患者的电刺激或另一类型治疗的技术。治疗修改可以基于由IMD检测到的患者的姿势和/或活动状态，例如患者所占据的检测到的姿势状态的变化。可以对检测到的姿势状态的不同变化应用不同的治疗修改。 IMD可以基于从一个姿势状态到另一个姿势状态的转变来修改治疗。 IMD可以确定用于控制治疗调整和/或系统的其他方面的患者的姿势状态。在一些示例中，当患者的运动和/或活动速度超过速度阈值时，可以使用患者的先前确定的稳定姿势状态来控制治疗而不是患者的当前姿势状态，其可以是暂时的。

7. 发明授权

US08515549B2 Associating therapy adjustments with intended patient posture states 有权
标题翻译：将治疗调整与预期的患者姿势状态相关联
公开(公告)号：US08515549B2
公开(公告)日：2013-08-20
申请号：US12433756
申请日：2009-04-30
申请人： Eric J. Panken , Dennis M. Skelton
发明人： Eric J. Panken , Dennis M. Skelton
IPC分类号： A61B5/00 , A61B5/02 , A61B5/103 , A61B5/11 , A61N1/00 , A61N1/05 , A61N1/372
CPC分类号： A61B5/1116 , A61B5/103 , A61B5/686 , A61B2560/0219 , A61B2562/0219 , A61N1/36071 , A61N1/36139 , A61N1/36535 , A61N1/37247 , G06F19/00 , G06F19/3481 , G16H40/63
摘要： The disclosure described techniques for associating therapy adjustments with intended patient posture states. The techniques may include receiving a patient therapy adjustment to a parameter of a therapy program that defines electrical stimulation therapy delivered to the patient, identifying a posture state of the patient, and associating the patient therapy adjustment with the posture state when the patient therapy adjustment is within a range determined based on stored adjustment information for the identified posture state.
摘要翻译：本公开描述了将治疗调整与预期患者姿势状态相关联的技术。这些技术可以包括接收患者治疗调整，该治疗程序的参数限定递送给患者的电刺激治疗，识别患者的姿势状态，以及当患者治疗调整为在基于所识别的姿势状态的存储的调整信息确定的范围内。

8. 发明授权

US08437861B2 Posture state redefinition based on posture data and therapy adjustments 有权
标题翻译：基于姿势数据和治疗调整的姿势状态重新定义
公开(公告)号：US08437861B2
公开(公告)日：2013-05-07
申请号：US12433858
申请日：2009-04-30
申请人： Dennis M. Skelton , Jon P. Davis
发明人： Dennis M. Skelton , Jon P. Davis
IPC分类号： A61N1/00
CPC分类号： A61N1/36135 , A61B5/1116 , A61B5/686 , A61B5/7435 , A61B2560/0219 , A61B2562/0219 , A61N1/36535 , A61N1/36542 , G06F19/00 , G06F19/3418 , G16H10/60 , G16H40/63 , G16H40/67 , G16H50/20
摘要： The disclosure is directed towards posture-responsive therapy. To avoid interruptions in effective therapy, an implantable medical device may include a posture state module that detects the posture state of the patient and automatically adjusts therapy parameter values according to the detected posture state. A system may include a posture state module that records a current posture of a patient, a user interface that receives a therapy adjustment, a processor that associates a posture that the posture state module recorded when the user interface received the therapy adjustment with the therapy adjustment, determines whether the posture falls within a defined posture state, compares the therapy adjustment to therapy information associated with the defined posture state, and updates the set of posture state definitions based on the determination and comparison.
摘要翻译：本公开涉及姿势响应疗法。为了避免有效治疗中断，可植入医疗装置可以包括检测患者的姿势状态的姿势状态模块，并且根据检测到的姿势状态自动调整治疗参数值。系统可以包括：姿势状态模块，其记录患者的当前姿势;接收治疗调整的用户界面;处理器，其将当所述用户界面接收到所述治疗调整时记录的姿势状态模块与所述治疗调整确定姿势是否落入规定的姿势状态，将治疗调整与与所定义的姿势状态相关联的治疗信息进行比较，并且基于判定和比较来更新姿势状态集合。

9. 发明授权

US08315710B2 Associating therapy adjustments with patient posture states 有权
标题翻译：将治疗调整与患者姿势状态相关联
公开(公告)号：US08315710B2
公开(公告)日：2012-11-20
申请号：US12433750
申请日：2009-04-30
申请人： Dennis M. Skelton , Jon P. Davis
发明人： Dennis M. Skelton , Jon P. Davis
IPC分类号： A61N1/365
CPC分类号： A61B5/1116 , A61B5/103 , A61B5/686 , A61B2560/0219 , A61B2562/0219 , A61N1/36071 , A61N1/36139 , A61N1/36535 , A61N1/37247 , G06F19/00 , G06F19/3481 , G16H40/63
摘要： The disclosure provides a method for associating a detected therapy adjustment to a posture state and storing the association with a plurality of associations for the posture state. In a record mode, an implantable medical device is configured to store therapy adjustments for each posture state and allow a user to find efficacious therapy based upon review of the associations made during therapy. The system may determine the associations through implementation of a posture search timer and a posture stability timer. These timers allow the system to correctly associate therapy adjustments to posture states when the patient anticipates the posture change by adjusting therapy before engaging in the desired posture state. An external programmer may present a range of the therapy adjustments for each posture state to allow a user to review the therapy adjustments that have been made during the therapy.
摘要翻译：本公开提供了一种用于将检测到的治疗调节与姿势状态相关联并且存储与用于姿势状态的多个关联的关联的方法。在记录模式中，可植入医疗装置被配置为存储针对每个姿势状态的治疗调整，并且允许用户基于对治疗期间所进行的关联的检查而找到有效的治疗。系统可以通过实施姿态搜索定时器和姿势稳定性定时器来确定关联。当患者在参与所需姿势状态之前通过调整治疗来预测姿势变化时，这些计时器允许系统将治疗调整正确地与姿势状态相关联。外部程序员可以呈现针对每个姿势状态的治疗调整范围，以允许用户复查治疗过程中进行的治疗调整。

10. 发明申请

US20120277638A1 OBTAINING BASELINE PATIENT INFORMATION 审中-公开
标题翻译：获得基线患者信息
公开(公告)号：US20120277638A1
公开(公告)日：2012-11-01
申请号：US13544222
申请日：2012-07-09
申请人： Dennis M. Skelton , Jon P. Davis , Dennis Bourget
发明人： Dennis M. Skelton , Jon P. Davis , Dennis Bourget
IPC分类号： A61B5/11
CPC分类号： A61B5/1116 , A61B5/0031 , A61B5/1118 , A61B5/4815 , A61B5/6846 , A61B5/686 , A61B2560/0219 , A61N1/0551 , A61N1/36071 , A61N1/36078 , A61N1/36085 , A61N1/36107 , A61N1/36132 , A61N1/36535 , A61N1/37247 , A61N1/37282 , G06F19/00
摘要： The disclosure relates to a method and system for obtaining baseline patient information. In some examples, a method may include acquiring first patient data, wherein the first patient data comprises at least one of first posture state data indicative of a plurality of posture states of a patient during a first time period or first therapy adjustment data indicative of a plurality of patient therapy adjustments made during the first time period; generating baseline patient information based at least in part on the first patient data; and comparing the baseline patient information to patient information generated based on second patient data. Therapy is not delivered to the patient according to a detected posture state of the patient during the first time period, and therapy is delivered to the patient according to the detected posture state of the patient during the second time period.
摘要翻译：本公开涉及一种用于获得基线患者信息的方法和系统。在一些示例中，方法可以包括获取第一患者数据，其中第一患者数据包括指示患者在第一时间段期间的多个姿势状态的第一姿势状态数据或指示患者的第一治疗调整数据中的至少一个在第一时期进行多次病人治疗调整; 至少部分地基于所述第一患者数据生成基线患者信息; 以及将基线患者信息与基于第二患者数据生成的患者信息进行比较。根据在第一时间段期间患者的检测到的姿势状态，不向患者传递治疗，并且根据在第二时间段期间检测到的患者的姿势状态将治疗递送给患者。

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