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    • 4. 发明申请
    • Method for Generating Images with an Expanded Dynamic Range and Optical Device for Carrying Out Such a Method, in Particular a Laser Scanner Microscope
    • 使用扩展动态范围生成图像的方法和用于执行这种方法的光学装置的方法,特别是激光扫描仪显微镜
    • US20120205519A1
    • 2012-08-16
    • US13435628
    • 2012-03-30
    • Gunter MöhlerDietmar SchmidtOliver Holub
    • Gunter MöhlerDietmar SchmidtOliver Holub
    • G01J1/44
    • G02B21/008G01J1/20G01J1/42
    • Method and apparatus for generating an at least two-dimensional image of at least part of a sample. The method involves scanning the sample. Acquiring at least one light signal by an optoelectronic detector for different areas of the sample. Converting the light signal into an electrical signal. Distributing the electrical signal onto several parallel evaluation channels whose signal evaluations differ from each other so that their dynamic ranges are different. Generating a result signal in each evaluation channel. Selecting at least one of the result signals as a function of one of the result signals in order to generate the image for the sample range concerned. It is also possible to generate one intermediate result signal for each channel, typically from the respective actual result signal and one or more other sources. Thus the signal selection depending on both the result signals and the intermediate result signals are possible.
    • 用于产生至少部分样品的至少二维图像的方法和装置。 该方法涉及扫描样品。 通过光电检测器获取至少一个光信号,以获得样品的不同区域。 将光信号转换为电信号。 将电信号分配到信号评估彼此不同的几个并行评估通道上,使得它们的动态范围不同。 在每个评估通道中生成结果信号。 选择结果信号中的至少一个作为结果信号之一的函数,以便生成所关注的样本范围的图像。 通常也可以从相应的实际结果信号和一个或多个其他源产生每个信道的一个中间结果信号。 因此,取决于结果信号和中间结果信号的信号选择是可能的。
    • 8. 发明授权
    • Method for generating images with an expanded dynamic range and optical device for carrying out such a method, in particular a laser scanner microscope
    • 用于产生具有扩展动态范围的图像的方法和用于执行这种方法的光学装置,特别是激光扫描显微镜
    • US08633430B2
    • 2014-01-21
    • US13435628
    • 2012-03-30
    • Gunter MöhlerDietmar SchmidtOliver Holub
    • Gunter MöhlerDietmar SchmidtOliver Holub
    • H01L27/00
    • G02B21/008G01J1/20G01J1/42
    • Method and apparatus for generating an at least two-dimensional image of at least part of a sample. The method involves scanning the sample. Acquiring at least one light signal by an optoelectronic detector for different areas of the sample. Converting the light signal into an electrical signal. Distributing the electrical signal onto several parallel evaluation channels whose signal evaluations differ from each other so that their dynamic ranges are different. Generating a result signal in each evaluation channel. Selecting at least one of the result signals as a function of one of the result signals in order to generate the image for the sample range concerned. It is also possible to generate one intermediate result signal for each channel, typically from the respective actual result signal and one or more other sources. Thus the signal selection depending on both the result signals and the intermediate result signals are possible.
    • 用于产生至少部分样品的至少二维图像的方法和装置。 该方法涉及扫描样品。 通过光电检测器获取至少一个光信号,以获得样品的不同区域。 将光信号转换为电信号。 将电信号分配到信号评估彼此不同的几个并行评估通道上,使得它们的动态范围不同。 在每个评估通道中生成结果信号。 选择结果信号中的至少一个作为结果信号之一的函数,以便生成所关注的样本范围的图像。 通常也可以从相应的实际结果信号和一个或多个其他源产生每个信道的一个中间结果信号。 因此,取决于结果信号和中间结果信号的信号选择是可能的。
    • 9. 发明申请
    • MICROSCOPE
    • 显微镜
    • US20110090561A1
    • 2011-04-21
    • US12905246
    • 2010-10-15
    • Peter KUEHNDietmar SchmidtThomas Mehner
    • Peter KUEHNDietmar SchmidtThomas Mehner
    • G02B21/06
    • G02B21/0044G02B21/008
    • In microscopes, particularly laser scanning microscopes, for detecting light coming from a sample, it is known to protect detectors from excessively high light outputs by means of shutters in the detection beam path. Further, in order to measure the light output impinging on the detector when the detection beam path is closed, a portion of the light is coupled out of the detection beam path and directed to a monitor diode. Constructions of this kind are complicated and costly. In the microscope according to the invention, a monitor diode is arranged on the shutter in such a way that the monitor diode is situated in the detection beam path when the shutter is closed. This makes it possible in a simple manner to measure the light output in a microscope when the detection beam path is closed even without additionally coupling light out of the detection beam path.
    • 在显微镜中,特别是用于检测来自样品的光的激光扫描显微镜,已知通过检测光束路径中的百叶窗来保护检测器免受过高的光输出。 此外,为了测量当检测光束路径闭合时入射到检测器上的光输出,光的一部分被耦合到检测光束路径外并被引导到监视二极管。 这样的建设是复杂和昂贵的。 在根据本发明的显微镜中,监视二极管被布置在快门上,使得当快门关闭时,监视二极管位于检测光束路径中。 这使得即使没有将光从检测光束路径附加到外部,当检测光束路径闭合时,也可以以简单的方式测量显微镜中的光输出。