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1. 发明授权

US08444578B2 Wearable ambulatory data recorder 有权
标题翻译：可佩戴的卧床数据记录仪
公开(公告)号：US08444578B2
公开(公告)日：2013-05-21
申请号：US13217011
申请日：2011-08-24
申请人： Duane L. Bourget , Keith A. Miesel , Gregory F. Molnar
发明人： Duane L. Bourget , Keith A. Miesel , Gregory F. Molnar
IPC分类号： A61B5/103
CPC分类号： A61N1/08 , A61B5/0002 , A61B5/0031 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/08 , A61B5/1116 , A61B5/1118 , A61B5/112 , A61B5/145 , A61B5/4082 , A61B5/4809 , A61B5/4815 , A61B5/4839 , A61B5/6831 , A61B5/6833 , A61B2560/0223 , A61B2560/0412 , A61B2560/0431 , A61B2562/0219 , A61N1/36021 , A61N1/36071 , A61N1/3702 , G06F19/00 , G06F19/3456 , G06F19/3481 , G16H10/60 , G16H40/63
摘要： A wearable ambulatory data recorder that senses physiological parameters of a patient, and stores physiological parameter data for later retrieval, as well as techniques for using such a wearable ambulatory data recorder, are described. The data recorder includes one or more sensors located on or within a housing. The data recorder may include an adhesive layer for attachment to a patient. In some embodiments, the housing may be within a patch, e.g., bandage, which includes the adhesive layer. The housing may be waterproof. Features of the data recorder such as size, waterproofness, and inclusion of an adhesive may allow the data recorder to be unobtrusively worn by a patient during a variety of daily activities. The data recorder may be for single use and thereafter disposable.
摘要翻译：描述了感测患者的生理参数并存储用于稍后检索的生理参数数据的可穿戴式步行数据记录器，以及使用这种可穿戴式可动态数据记录器的技术。数据记录器包括位于壳体上或壳体内的一个或多个传感器。数据记录器可以包括用于附接到患者的粘合剂层。在一些实施例中，壳体可以在包括粘合剂层的贴片（例如绷带）内。外壳可能是防水的。诸如尺寸，防水性和包含粘合剂的数据记录器的特征可允许数据记录器在各种日常活动期间被患者不佩服地佩戴。数据记录器可以是单次使用的，然后是一次性的。

2. 发明授权

US08903486B2 Closed-loop therapy adjustment 有权
标题翻译：闭环治疗调整
公开(公告)号：US08903486B2
公开(公告)日：2014-12-02
申请号：US12966827
申请日：2010-12-13
申请人： Duane L. Bourget , Keith A. Miesel
发明人： Duane L. Bourget , Keith A. Miesel
IPC分类号： A61N1/00 , A61N1/372 , A61N1/36
CPC分类号： A61N1/37247 , A61N1/36014 , A61N1/36071 , A61N1/37252
摘要： Techniques for detecting a value of a sensed patient parameter, and automatically delivering therapy to a patient according to therapy information previously associated with the detected value, are described. In exemplary embodiments, a medical device receives a therapy adjustment from the patient. In response to the adjustment, the medical device associates a sensed value of a patient parameter with therapy information determined based on the adjustment. Whenever the parameter value is subsequently detected, the medical device delivers therapy according to the associated therapy information. In this manner, the medical device may “learn” to automatically adjust therapy in the manner desired by the patient as the sensed parameter of the patient changes. Exemplary patient parameters that may be sensed for performance of the described techniques include posture, activity, heart rate, electromyography (EMG), an electroencephalogram (EEG), an electrocardiogram (ECG), temperature, respiration rate, and pH.
摘要翻译：描述了用于检测感测到的患者参数的值并根据先前与检测值相关联的治疗信息自动地向患者递送治疗的技术。在示例性实施例中，医疗设备从患者接收治疗调节。响应于调整，医疗设备将感测到的患者参数值与基于调整确定的治疗信息相关联。每当随后检测到参数值时，医疗装置根据相关联的治疗信息递送治疗。以这种方式，当患者的感测参数改变时，医疗设备可以“学习”以患者期望的方式自动调整治疗。可以感测用于执行所述技术的示例性患者参数包括姿势，活动，心率，肌电图（EMG），脑电图（EEG），心电图（ECG），温度，呼吸速率和pH。

3. 发明授权

US08579834B2 Display of detected patient posture state 有权
公开(公告)号：US08579834B2
公开(公告)日：2013-11-12
申请号：US12985965
申请日：2011-01-06
申请人： Jon P. Davis , Duane L. Bourget , Mandla Shongwe , Rajeev M. Sahasrabudhe
发明人： Jon P. Davis , Duane L. Bourget , Mandla Shongwe , Rajeev M. Sahasrabudhe
IPC分类号： A61B5/103 , A61N1/365 , A61B5/11 , A61B5/00
CPC分类号： A61N1/36535 , A61B5/0031 , A61B5/01 , A61B5/024 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/0816 , A61B5/1116 , A61B5/1118 , A61B5/14539 , A61B5/686 , A61B5/744 , A61B2560/0219 , A61N1/36 , A61N1/37247 , G06F19/00 , G06F19/3418 , G16H15/00 , G16H40/63
摘要： The disclosure provides a system that displays an indicator of patient posture state that changes according to posture state data. The posture state data may be transmitted from a medical device, for example, in or near real-time. In some examples, the disclosure relates to a method comprising receiving posture state data for a patient from a medical device; and presenting an indicator indicative of two or more of posture states based on the received posture state data, wherein each posture state of the two or more posture states is determined based on different detection criteria.

4. 发明申请

US20110172743A1 DISPLAY OF DETECTED PATIENT POSTURE STATE 有权
标题翻译：检测患者姿态的显示
公开(公告)号：US20110172743A1
公开(公告)日：2011-07-14
申请号：US12985965
申请日：2011-01-06
申请人： Jon P. Davis , Duane L. Bourget , Mandla Shongwe , Rajeev M. Sahasrabudhe
发明人： Jon P. Davis , Duane L. Bourget , Mandla Shongwe , Rajeev M. Sahasrabudhe
IPC分类号： A61N1/36 , G08B23/00
CPC分类号： A61N1/36535 , A61B5/0031 , A61B5/01 , A61B5/024 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/0816 , A61B5/1116 , A61B5/1118 , A61B5/14539 , A61B5/686 , A61B5/744 , A61B2560/0219 , A61N1/36 , A61N1/37247 , G06F19/00 , G06F19/3418 , G16H15/00 , G16H40/63
摘要： The disclosure provides a system that displays an indicator of patient posture state that changes according to posture state data. The posture state data may be transmitted from a medical device, for example, in or near real-time. In some examples, the disclosure relates to a method comprising receiving posture state data for a patient from a medical device; and presenting an indicator indicative of two or more of posture states based on the received posture state data, wherein each posture state of the two or more posture states is determined based on different detection criteria.
摘要翻译：本公开提供了显示根据姿势状态数据而改变的患者姿势状态的指示符的系统。姿势状态数据可以从医疗装置例如实时地或接近实时地发送。在一些示例中，本公开涉及一种包括从医疗装置接收患者的姿势状态数据的方法; 并且基于接收到的姿势状态数据呈现指示姿势状态的两个以上的指标，其中，基于不同的检测标准来确定两个以上的姿势状态的各姿势状态。

5. 发明授权

US08731656B2 Closed-loop therapy adjustment 有权
公开(公告)号：US08731656B2
公开(公告)日：2014-05-20
申请号：US13154309
申请日：2011-06-06
申请人： Duane L. Bourget , Keith A. Miesel
发明人： Duane L. Bourget , Keith A. Miesel
IPC分类号： A61N1/00
CPC分类号： A61N1/37211 , A61N1/36071 , A61N1/37247 , A61N1/37252 , G06F19/00 , G06F19/3456 , G06F19/3481 , G16H40/63
摘要： Techniques for detecting a value of a sensed patient parameter, and automatically delivering therapy to a patient according to therapy information previously associated with the detected value, are described. In exemplary embodiments, a medical device receives a therapy adjustment from the patient. In response to the adjustment, the medical device associates a sensed value of a patient parameter with therapy information determined based on the adjustment. Whenever the parameter value is subsequently detected, the medical device delivers therapy according to the associated therapy information. In this manner, the medical device may “learn” to automatically adjust therapy in the manner desired by the patient as the sensed parameter of the patient changes. Exemplary patient parameters that may be sensed for performance of the described techniques include posture, activity, heart rate, electromyography (EMG), an electroencephalogram (EEG), an electrocardiogram (ECG), temperature, respiration rate, and pH.

6. 发明申请

US20120197356A1 Waveforms for Remote Electrical Stimulation Therapy 审中-公开
标题翻译：用于远程电刺激治疗的波形
公开(公告)号：US20120197356A1
公开(公告)日：2012-08-02
申请号：US13355122
申请日：2012-01-20
申请人： Xuan Wei , Duane L. Bourget
发明人： Xuan Wei , Duane L. Bourget
IPC分类号： A61N1/36
CPC分类号： A61N1/36171 , A61N1/36189
摘要： Electrical stimulation systems and methods are configured to deliver remote electrical stimulation to a patient. Stimulation waveforms are employed that are designed to penetrate tissue within a patient to transmit the electrical stimulation from an origination site to a remote delivery site. The waveforms are defined by a series of pulses, which are characterized by a number of parameters, including pulse width, pulse frequency, constant voltage or constant current amplitude, and electrode polarity (anode or cathode). The waveforms include an envelope electrical stimulation pulse train including charge balanced pulses modulated by a high frequency carrier signal configured to deeply penetrate patient tissue to carry the electrical pulse train from an origination site to a remote delivery site.
摘要翻译：电刺激系统和方法被配置为向患者传送远程电刺激。采用刺激波形，其被设计为穿透患者体内的组织，以将电刺激从始发部位传输到远程递送部位。波形由一系列脉冲定义，脉冲的特征在于包括脉冲宽度，脉冲频率，恒定电压或恒定电流幅度以及电极极性（阳极或阴极）的多个参数。这些波形包括包络电刺激脉冲串，其包括被高频载波信号调制的电荷平衡脉冲，该高频载波信号被配置为深入穿透患者组织，以将电脉冲串从始发部位运送到远程传送部位。

7. 发明申请

US20130110008A1 COMMUNICATION BETWEEN EXTERNAL DEVICES AND IMPLANTABLE MEDICAL DEVICES 审中-公开
标题翻译：外部设备和可植入医疗设备之间的通信
公开(公告)号：US20130110008A1
公开(公告)日：2013-05-02
申请号：US13284696
申请日：2011-10-28
申请人： Duane L. Bourget , Jay T. Eisch , Yu Wang
发明人： Duane L. Bourget , Jay T. Eisch , Yu Wang
IPC分类号： A61B5/11 , H04W12/04 , H04W12/06 , A61B5/103
CPC分类号： A61B5/686 , A61B5/002 , A61B5/076 , A61B5/11 , H04W12/0013 , H04W12/003 , H04W12/00504 , H04W12/06
摘要： In general, the techniques of this disclosure are directed to communication between an implantable medical device (IMD) and an external device. In some examples, the external device transmits a signal that includes a communication key. One or more sensors of the IMD sense the signal that includes the communication key, and the IMD uses the communication key for coding the communication between the IMD and the external device. The one or more sensors that sensed the signal may also sense one or more patient characteristics.
摘要翻译：通常，本公开的技术涉及可植入医疗装置（IMD）和外部装置之间的通信。在一些示例中，外部设备发送包括通信密钥的信号。 IMD的一个或多个传感器感测到包括通信密钥的信号，IMD使用通信密钥对IMD和外部设备之间的通信进行编码。感测信号的一个或多个传感器也可以感测一个或多个患者特征。

8. 发明授权

US07776031B2 Method and apparatus to control drug therapy dosages in an implantable pump 有权
标题翻译：在可植入泵中控制药物治疗剂量的方法和装置
公开(公告)号：US07776031B2
公开(公告)日：2010-08-17
申请号：US10921015
申请日：2004-08-18
申请人： Jerome T. Hartlaub , Duane L. Bourget
发明人： Jerome T. Hartlaub , Duane L. Bourget
IPC分类号： A61K9/22
CPC分类号： G05B19/106 , A61M5/14276 , A61M2005/1405 , A61M2005/14208 , A61M2205/3523 , A61M2205/52 , G06F19/00 , G06F19/3468
摘要： An implantable drug infusion pump for delivering drug therapy to a patient and which also permits a patient to deliver or self-administer an additional bolus, reduces the likelihood of over dosage or under dosage by drug dosage characteristic limitations programmed into a microprocessor memory. The dose limits define the maximum and minimum amount of drug to be delivered per unit time or otherwise, reducing the likelihood that a patient may inadvertently or deliberately interfere with a treatment regimen.
摘要翻译：用于向患者递送药物治疗并且还允许患者递送或自我施用另外的推注的可植入药物输注泵减少了编程到微处理器存储器中的药物剂量特征限制的过度剂量或剂量的可能性。剂量限度定义每单位时间或其他方式递送的药物的最大和最小量，减少患者可能无意或故意干扰治疗方案的可能性。

9. 发明授权

US06796956B2 Method and apparatus to control drug therapy dosages in an implantable pump 有权
标题翻译：在可植入泵中控制药物治疗剂量的方法和装置
公开(公告)号：US06796956B2
公开(公告)日：2004-09-28
申请号：US09804136
申请日：2001-03-12
申请人： Jerome T Hartlaub , Duane L Bourget
发明人： Jerome T Hartlaub , Duane L Bourget
IPC分类号： A61M3100
CPC分类号： G05B19/106 , A61M5/14276 , A61M2005/1405 , A61M2005/14208 , A61M2205/3523 , A61M2205/52 , G06F19/00 , G06F19/3468
摘要： An implantable drug infusion pump for delivering drug therapy to a patient and which also permits a patient to deliver or self-administer an additional bolus, reduces the likelihood of over dosage or under dosage by drug dosage characteristic limitations programmed into a microprocessor memory. The dose limits define the maximum and minimum amount of drug to be delivered per unit time or otherwise, reducing the likelihood that a patient may inadvertently or deliberately interfere with a treatment regimen.
摘要翻译：用于向患者递送药物治疗并且还允许患者递送或自我施用另外的推注的可植入药物输注泵减少了编程到微处理器存储器中的药物剂量特征限制的过度剂量或剂量的可能性。剂量限度定义每单位时间或其他方式递送的药物的最大和最小量，减少患者可能无意或故意干扰治疗方案的可能性。

10. 发明授权

US06647299B2 Patient programmer for implantable medical device with audio locator signal 有权
标题翻译：具有音频定位信号的可植入医疗设备的患者程序员
公开(公告)号：US06647299B2
公开(公告)日：2003-11-11
申请号：US09960095
申请日：2001-09-21
申请人： Duane L. Bourget
发明人： Duane L. Bourget
IPC分类号： A61N137
CPC分类号： A61N1/08 , Y10S128/903
摘要： A system and method of locating the desired telemetry location for an implantable medical device includes a programmer having a patient interface to allow activation of the programmer, a bi-directional communications link between the programmer and the implantable device, an automatic gain control for determining the gain setting for a received signal from the implantable device, and an audio transducer for emitting audio signals to the patient. The bi-directional communications link enables the programmer to locate the desired telemetry location for the implantable device, the automatic gain control provides for optimum telemetry communication between the programmer and the implantable device, and the audio transducer generates audio signals indicative of the telemetry communication between the programmer and the implantable device.
摘要翻译：定位用于可植入医疗设备的所需遥测位置的系统和方法包括具有患者接口以允许编程器激活的编程器，编程器和可植入装置之间的双向通信链路，用于确定用于来自可植入装置的接收信号的增益设置，以及用于向患者发射音频信号的音频换能器。双向通信链路使得编程器能够定位用于可植入装置的期望的遥测位置，自动增益控制提供编程器和可植入装置之间的最佳遥测通信，并且音频传感器产生指示在可植入装置之间的遥测通信的音频信号编程器和可植入装置。

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