专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08859815B2 Sulphonylated diphenylethylenediamines, method for their preparation and use in transfer hydrogenation catalysis 有权
标题翻译：磺酰化二苯基乙二胺，其制备方法和用于转移氢化催化
公开(公告)号：US08859815B2
公开(公告)日：2014-10-14
申请号：US13313889
申请日：2011-12-07
申请人： Beatriz Dominguez , Antonio Zanotti-Gerosa , Gabriela Alexandra Grasa , Jonathan Alan Medlock
发明人： Beatriz Dominguez , Antonio Zanotti-Gerosa , Gabriela Alexandra Grasa , Jonathan Alan Medlock
IPC分类号： C07C311/13 , C07C311/14 , C07C311/16 , C07C33/20 , C07C33/22 , C07C33/46 , C07C303/38 , B01J31/18 , C07C29/143 , C07C311/18
CPC分类号： B01J31/1805 , B01J2231/643 , B01J2531/821 , B01J2531/822 , B01J2531/824 , B01J2531/827 , B01J2531/828 , B01J2531/842 , B01J2531/845 , B01J2531/847 , C07B2200/07 , C07C29/143 , C07C311/18 , C07C2602/10 , C07C33/46 , C07C33/22 , C07C35/32
摘要： A diamine of formula (I) is described in which A is hydrogen or a saturated or unsaturated C1-C20 alkyl group or an aryl group; B is a substituted or unsubstituted C1-C20 alkyl, cycloalkyl, alkaryl, alkaryl or aryl group or an alkylamino group and at least one of X1, X2, Y1, Y2 or Z is a C1-C10 alkyl, cycloalkyl, alkaryl, aralkyl or alkoxy substituting group. The chiral diamine may be used to prepare catalysts suitable for use in transfer hydrogenation reactions.
摘要翻译：描述了式（I）的二胺，其中A是氢或饱和或不饱和的C 1 -C 20烷基或芳基; B是取代或未取代的C 1 -C 20烷基，环烷基，烷芳基，烷芳基或芳基或烷基氨基，X 1，X 2，Y 1，Y 2或Z中的至少一个是C 1 -C 10烷基，环烷基，烷芳基，芳烷基或烷氧基取代基。手性二胺可用于制备适用于转移氢化反应的催化剂。

2. 发明授权

US08039675B2 Catalysts 失效
标题翻译：催化剂
公开(公告)号：US08039675B2
公开(公告)日：2011-10-18
申请号：US12696736
申请日：2010-01-29
申请人： William Patrick Hems , Gabriela Alexandra Grasa
发明人： William Patrick Hems , Gabriela Alexandra Grasa
IPC分类号： C07C209/26 , C07F15/00 , C07F9/02
CPC分类号： C07D207/14 , C07F15/0053
摘要： Catalysts suitable for asymmetric hydrogenation reactions are described comprising the reaction product of a group 8 transition metal compound, a chiral phosphine and a chiral diamine of formula (I) in which R1, R2, R3 and R4 are independently hydrogen, a saturated or unsaturated alkyl or cycloalkyl group, an aryl group or a urethane or sulphonyl group and R5, R6, R7 and R8 are independently hydrogen, a saturated or unsaturated alkyl or cycloalkyl group, or an aryl group, at least one of R1, R2, R3 and R4 is hydrogen and A is a linking group comprising one or two substituted or unsubstituted carbon atoms.
摘要翻译：描述了适用于不对称氢化反应的催化剂，其包括第8族过渡金属化合物，手性膦和式（I）的手性二胺的反应产物，其中R 1，R 2，R 3和R 4独立地为氢，饱和或不饱和烷基或环烷基，芳基或氨基甲酸酯或磺酰基，R 5，R 6，R 7和R 8独立地为氢，饱和或不饱和的烷基或环烷基或芳基，R 1，R 2，R 3和R 4中的至少一个是氢并且A是包含一个或两个取代或未取代的碳原子的连接基团。

3. 发明授权

US08288532B2 Asymmetric catalytic reduction of oxcarbazepine 有权
标题翻译：奥卡西平的不对称催化还原
公开(公告)号：US08288532B2
公开(公告)日：2012-10-16
申请号：US11997104
申请日：2006-04-21
申请人： David Alexander Learmonth , Gabriela Alexandra Grasa , Antonio Zanotti-Gerosa
发明人： David Alexander Learmonth , Gabriela Alexandra Grasa , Antonio Zanotti-Gerosa
IPC分类号： C07D223/22
CPC分类号： C07D223/28 , A61K31/55 , C07D223/22
摘要： A process for preparing (S)-(+)-10,11-dihydro-10-hydroxy-5H-dibenz/b,f/azepine-5-carboxamide or (R)-(−)-10,11-dihydro-10-hydroxy-5H-dibenz/b,f/azepine-5-carboxamide, by reduction of oxcarbazepine in the presence of a catalyst and a hydride source is disclosed. The catalyst is prepared from a combination of [RuX2(L)]2 wherein X is chlorine, bromine or iodine, and L is an aryl or aryl-aliphatic ligand, with a ligand of formula (A) or formula (B): wherein R1 is chosen from C1-6 alkoxy and C1-6 alkyl, n is a number from 0 to 5, and when n is a number from 2 to 5, R1 can be the same or different, and R2 is alkyl, substituted alkyl, aryl, substituted aryl, alkaryl or substituted alkaryl. The hydride source is either NR3R4R5 and formic acid, [R3R4R5NH][OOCH] and optionally formic acid, or [M][OOCH]x and formic acid, wherein R3, R4 and R5 are C1-6 alkyl, M is an alkali metal or alkaline earth metal and x is 1 or 2. A pH from 6.5 to 8 is maintained during the process.
摘要翻译：制备（S） - （+） - 10,11-二氢-10-羟基-5H-二苯并/ b，f /氮杂-5-甲酰胺或（R） - （ - ） - 10,11-二氢 - 公开了在催化剂和氢化物源存在下还原奥卡西平的方法，其中10-羟基-5H-二苯并/ b，f /吖庚因-5-甲酰胺。催化剂由[RuX 2（L）] 2（其中X是氯，溴或碘）和L是芳基或芳基 - 脂族配体与式（A）或式（B）的配体的组合制备：其中 R 1选自C 1-6烷氧基和C 1-6烷基，n为0至5的数，当n为2至5的数时，R 1可相同或不同，并且R 2为烷基，取代的烷基，芳基，取代的芳基，烷芳基或取代的烷芳基。氢化物源是NR3R4R5和甲酸，[R3R4R5NH] [OOCH]和任选的甲酸或[M] [OOCH] x和甲酸，其中R3，R4和R5是C1-6烷基，M是碱金属或碱土金属，x为1或2.在该过程中维持6.5至8的pH。

4. 发明申请

US20120116109A1 PREPARATION OF A METAL COMPLEX 有权
标题翻译：金属复合物的制备
公开(公告)号：US20120116109A1
公开(公告)日：2012-05-10
申请号：US13318970
申请日：2010-01-12
申请人： Thomas John Colacot , Gabriela Alexandra Grasa , Hongbo Li
发明人： Thomas John Colacot , Gabriela Alexandra Grasa , Hongbo Li
IPC分类号： C07F7/24
CPC分类号： C07F15/0066 , C07F15/006 , C07F17/02
摘要： The present invention provides a process for the preparation of a Pd(0)Ln complex, where L is a ligand and n is 2, 3 or 4, comprising the steps of: (a) reacting a Pd(II) complex in at least one solvent with a base and ligand L; and (b) if required, adding further base, optionally in at least one solvent, to form the Pd(0)Ln complex; wherein the at least one solvents in steps a and b are independently the same or different, and provided that when n=2, the Pd(II) complex is not bis[tri(ortho-tolyl)phosphine] palladium chloride. The invention also provides novel Pd(0)L2 and Pd(II) complexes.
摘要翻译：本发明提供了制备Pd（O）Ln络合物的方法，其中L为配体，n为2,3或4，包括以下步骤：（a）使Pd（II）络合物至少一种溶剂与碱和配体L; 和（b）如果需要，另外加入碱，任选地在至少一种溶剂中，形成Pd（0）Ln络合物; 其中步骤a和b中的至少一种溶剂独立地相同或不同，条件是当n = 2时，Pd（II）络合物不是双[三（邻 - 甲苯基）膦]氯化钯。本发明还提供了新颖的Pd（O）L2和Pd（II）络合物。

5. 发明申请

US20120077973A1 Sulphonylated Diphenylethylenediamines, Method for Their Preparation and Use in Transfer Hydrogenation Catalysis 有权
标题翻译：磺酰化二苯乙二胺，其制备方法及其在转移氢化催化中的应用
公开(公告)号：US20120077973A1
公开(公告)日：2012-03-29
申请号：US13313889
申请日：2011-12-07
申请人： Beatriz Dominguez , Antonio Zanotti-Gerosa , Gabriela Alexandra Grasa , Jonathan Alan Medlock
发明人： Beatriz Dominguez , Antonio Zanotti-Gerosa , Gabriela Alexandra Grasa , Jonathan Alan Medlock
IPC分类号： C07D223/18 , B01J31/02 , C07C311/10
CPC分类号： B01J31/1805 , B01J2231/643 , B01J2531/821 , B01J2531/822 , B01J2531/824 , B01J2531/827 , B01J2531/828 , B01J2531/842 , B01J2531/845 , B01J2531/847 , C07B2200/07 , C07C29/143 , C07C311/18 , C07C2602/10 , C07C33/46 , C07C33/22 , C07C35/32
摘要： A diamine of formula (I) is described in which A is hydrogen or a saturated or unsaturated C1-C20 alkyl group or an aryl group; B is a substituted or unsubstituted C1-C20 alkyl, cycloalkyl, alkaryl, alkaryl or aryl group or an alkylamino group and at least one of X1, X2, Y1, Y2 or Z is a C1-C10 alkyl, cycloalkyl, alkaryl, aralkyl or alkoxy substituting group. The chiral diamine may be used to prepare catalysts suitable for use in transfer hydrogenation reactions.
摘要翻译：描述了式（I）的二胺，其中A是氢或饱和或不饱和的C 1 -C 20烷基或芳基; B是取代或未取代的C 1 -C 20烷基，环烷基，烷芳基，烷芳基或芳基或烷基氨基，并且X 1，X 2，Y 1，Y 2或Z中的至少一个是C 1 -C 10烷基，环烷基，烷芳基，芳烷基或烷氧基取代基。手性二胺可用于制备适用于转移氢化反应的催化剂。

6. 发明申请

US20100197976A1 CATALYSTS 失效
标题翻译：催化剂
公开(公告)号：US20100197976A1
公开(公告)日：2010-08-05
申请号：US12696736
申请日：2010-01-29
申请人： William Patrick Hems , Gabriela Alexandra Grasa
发明人： William Patrick Hems , Gabriela Alexandra Grasa
IPC分类号： C07C29/136 , B01J31/02 , B01J23/46
CPC分类号： C07D207/14 , C07F15/0053
摘要： Catalysts suitable for asymmetric hydrogenation reactions is described comprising the reaction product of a group 8 transition metal compound a chiral phosphine and a chiral diamine of formula (I) in which R1, R2, R3 and R4 are independently hydrogen, a saturated or unsaturated alkyl or cycloalkyl group, an aryl group or a urethane or sulphonyl group and R5, R6, R7 and R8 are independently hydrogen, a saturated or unsaturated alkyl or cycloalkyl group, or an aryl group, at least one of R1, R2, R3 and R4 is hydrogen and A is a linking group comprising one or two substituted or unsubstituted carbon atoms.
摘要翻译：描述适用于不对称氢化反应的催化剂，其包括第8族过渡金属化合物手性膦和式（I）的手性二胺的反应产物，其中R 1，R 2，R 3和R 4独立地为氢，饱和或不饱和烷基或环烷基，芳基或氨基甲酸酯或磺酰基，R 5，R 6，R 7和R 8独立地为氢，饱和或不饱和的烷基或环烷基或芳基，R 1，R 2，R 3和R 4中的至少一个为氢和A是包含一个或两个取代或未取代的碳原子的连接基团。

7. 发明授权

US07601867B2 Sulphonylated diphenylethylenediamines, method for their preparation and use in transfer hydrogenation catalysis 有权
公开(公告)号：US07601867B2
公开(公告)日：2009-10-13
申请号：US11719478
申请日：2005-11-01
申请人： Beatriz Dominguez , Antonio Zanotti-Gerosa , Gabriela Alexandra Grasa , Jonathan Alan Medlock
发明人： Beatriz Dominguez , Antonio Zanotti-Gerosa , Gabriela Alexandra Grasa , Jonathan Alan Medlock
IPC分类号： C07C311/21 , C07C311/16 , C07C311/03 , C07C303/38
摘要： A diamine of formula (I) is described, in which A is hydrogen or a saturated or unsaturated C1-C20 alkyl group or an aryl group; B is a substituted or unsubstituted C1-C20 alkyl, cycloalkyl, alkaryl, alkaryl or aryl group or an alkylamino group and at least one of X1, X2, Y1, Y2 or Z is a C1-C10 alkyl, cycloalkyl, alkaryl, aralkyl or alkoxy substituting group. The chiral diamine may be used to prepare catalysts suitable for use in transfer hydrogenation reactions.

8. 发明授权

US08772520B2 Preparation of a metal complex 有权
标题翻译：制备金属络合物
公开(公告)号：US08772520B2
公开(公告)日：2014-07-08
申请号：US13318970
申请日：2010-01-12
申请人： Thomas John Colacot , Gabriela Alexandra Grasa , Hongbo Li
发明人： Thomas John Colacot , Gabriela Alexandra Grasa , Hongbo Li
IPC分类号： C07F15/00 , C07F9/02
CPC分类号： C07F15/0066 , C07F15/006 , C07F17/02
摘要： The present invention provides a process for the preparation of a Pd(0)Ln complex, where L is a ligand and n is 2, 3 or 4, comprising the steps of: (a) reacting a Pd(II) complex in at least one solvent with a base and ligand L; and (b) if required, adding further base, optionally in at least one solvent, to form the Pd(0)Ln complex; wherein the at least one solvents in steps a and b are independently the same or different, and provided that when n=2, the Pd(II) complex is not bis[tri(ortho-tolyl)phosphine] palladium chloride. The invention also provides novel Pd(0)L2 and Pd(II) complexes.
摘要翻译：本发明提供了制备Pd（O）Ln络合物的方法，其中L为配体，n为2,3或4，包括以下步骤：（a）使Pd（II）络合物至少一种溶剂与碱和配体L; 和（b）如果需要，另外加入碱，任选地在至少一种溶剂中，形成Pd（0）Ln络合物; 其中步骤a和b中的至少一种溶剂独立地相同或不同，条件是当n = 2时，Pd（II）络合物不是双[三（邻 - 甲苯基）膦]氯化钯。本发明还提供了新颖的Pd（O）L2和Pd（II）络合物。

9. 发明授权

US08618318B2 Process for the preparation of palladium (I) tri-tert-butylphosphine bromide dimer 有权
标题翻译：制备钯（I）三叔丁基溴化膦二聚体的方法
公开(公告)号：US08618318B2
公开(公告)日：2013-12-31
申请号：US13387593
申请日：2010-07-27
申请人： Thomas John Colacot , Mark William Hooper , Gabriela Alexandra Grasa
发明人： Thomas John Colacot , Mark William Hooper , Gabriela Alexandra Grasa
IPC分类号： C07F15/00
CPC分类号： C07F15/0066
摘要： The present invention provides a process for the preparation of a complex of formula (I) comprising the steps of: (a) mixing Pd(diolefin)Br2 and tBu3P in a solvent; and (b) adding an alkali hydroxide to form the complex of formula (I).
摘要翻译：本发明提供制备式（I）配合物的方法，包括以下步骤：（a）将Pd（二烯烃）Br 2和tBu 3 P在溶剂中混合; 和（b）加入碱金属氢氧化物以形成式（I）的络合物。

10. 发明申请

US20120190873A1 PROCESS FOR THE PREPARATION OF PALLADIUM (I) TRI-TERT-BUTYLPHOSPHINE BROMIDE DIMER 有权
标题翻译：哌嗪（I）三叔丁基磷酰胺二聚体的制备方法
公开(公告)号：US20120190873A1
公开(公告)日：2012-07-26
申请号：US13387593
申请日：2010-07-27
申请人： Thomas John Colacot , Mark William Hooper , Gabriela Alexandra Grasa
发明人： Thomas John Colacot , Mark William Hooper , Gabriela Alexandra Grasa
IPC分类号： C07F15/00
CPC分类号： C07F15/0066
摘要： The present invention provides a process for the preparation of a complex of formula (I) comprising the steps of: (a) mixing Pd(diolefin)Br2 and tBu3P in a solvent; and (b) adding an alkali hydroxide to form the complex of formula (I).
摘要翻译：本发明提供制备式（I）配合物的方法，包括以下步骤：（a）将Pd（二烯烃）Br 2和tBu 3 P在溶剂中混合; 和（b）加入碱金属氢氧化物以形成式（I）的络合物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式