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1. 发明申请

US20140131399A1 SELECTIVE OPERATION VALVE FOR A RECIPIENT FOR BIOPHARMACEUTICAL USE 有权
标题翻译：选择性操作阀用于生物医学用途的接收者
公开(公告)号：US20140131399A1
公开(公告)日：2014-05-15
申请号：US14131982
申请日：2012-07-12
申请人： Florian Blake , Jeremy Gibelin
发明人： Florian Blake , Jeremy Gibelin
IPC分类号： F16K3/26 , B65D47/26 , B65D47/00
CPC分类号： F16K3/262 , B65D47/00 , B65D47/261 , F16K3/265 , Y10T137/87877
摘要： The valve includes a female part having a closed, transverse, proximal end wall, and a tubular wall integral with a flange part, a lateral opening being formed on the proximal section of the tubular wall, a male part having a tubular wall forming, on the proximal side, a closing/opening part having an open, transverse, proximal end; the closing/opening part has an external shape and an external dimension that fit the internal shape and internal dimension of the proximal receiving part of the female part. The sealing elements include three ring seals separated from one another in an axial direction, supported by the upper surface of the tubular wall of the male part and engaging with the female part, a proximal seal to the fluid product, a distal seal to external contaminants, and an intermediate seal to the fluid product and to external contaminants between the proximal and distal seals.
摘要翻译：该阀包括一个阴部分，其具有封闭的，横向的近端壁，以及与凸缘部分成一体的管状壁，在该管状壁的近端部分上形成的侧向开口，近侧，具有开放横向近端的封闭/开口部分; 闭合/打开部分具有外部形状和外部尺寸，其适合阴部件的近侧接收部分的内部形状和内部尺寸。密封元件包括在轴向上彼此分离的三个环形密封件，由阳部件的管状壁的上表面支撑并与阴部件接合，与流体产品的近端密封件，对外部污染物的远端密封件以及对流体产品的中间密封和近端和远端密封之间的外部污染物。

2. 发明申请

US20140150924A1 LEAKTIGHT JOINING DEVICE FOR THE ASEPTIC TRANSFER OF A BIOPHARMACEUTICAL PRODUCT BETWEEN A CHAMBER AND A CONTAINER 有权
标题翻译：用于室内和集装箱之间的生物制品的无接触传递的疏密接合装置
公开(公告)号：US20140150924A1
公开(公告)日：2014-06-05
申请号：US14234788
申请日：2012-07-12
申请人： Gaelle Nodin , Jeremy Gibelin
发明人： Gaelle Nodin , Jeremy Gibelin
IPC分类号： B67D7/44
CPC分类号： B01L1/02 , C12M37/04 , G21F7/005
摘要： A leaktight joining device for ensuring the aseptic transfer of a biopharmaceutical product between a chamber equipped with a removable door and a container equipped with a removable cover, includes: stationary temporary flanging elements, stationary unlocking elements capable of changing the container from an initial locking position to an intermediate unlocking position so as to ensure an aseptic communication between the container and the chamber, stationary locking element capable of changing the container from the intermediate locking position to a final locking position, an annular functional ring gear capable of actuating the stationary unlocking elements and the stationary locking elements of the container. The stationary temporary flanging elements, the stationary unlocking elements, and the stationary locking elements are mechanically linked to the annular functional ring gear and arranged so that the unidirectional rotation of the annular functional ring gear about the geometric axis of rotation successively drives the actuation thereof.
摘要翻译：一种用于确保生物制药产品在装有可拆卸门的室与装有可移除盖的容器之间无菌转移的密封接合装置包括：固定的临时折边元件，能够将容器从初始锁定位置改变的固定解锁元件以确保容器和腔室之间的无菌连通，能够将容器从中间锁定位置改变到最终锁定位置的固定锁定元件，能够致动固定解锁元件的环形功能性环形齿轮和容器的固定锁定元件。固定的临时折边元件，固定解锁元件和固定锁定元件机械地连接到环形功能性环形齿轮并且被布置成使得环形功能性环形齿轮围绕旋转几何轴线的单向旋转连续地驱动其致动。

3. 发明授权

US09212750B2 Selective operation valve for a recipient for biopharmaceutical use 有权
标题翻译：用于生物制药用途接受者的选择性操作阀
公开(公告)号：US09212750B2
公开(公告)日：2015-12-15
申请号：US14131982
申请日：2012-07-12
申请人： Florian Blake , Jeremy Gibelin
发明人： Florian Blake , Jeremy Gibelin
IPC分类号： F16K3/26 , B65D47/00 , B65D47/26
CPC分类号： F16K3/262 , B65D47/00 , B65D47/261 , F16K3/265 , Y10T137/87877
摘要： The valve includes a female part having a closed, transverse, proximal end wall, and a tubular wall integral with a flange part, a lateral opening being formed on the proximal section of the tubular wall, a male part having a tubular wall forming, on the proximal side, a closing/opening part having an open, transverse, proximal end; the closing/opening part has an external shape and an external dimension that fit the internal shape and internal dimension of the proximal receiving part of the female part. The sealing elements include three ring seals separated from one another in an axial direction, supported by the upper surface of the tubular wall of the male part and engaging with the female part, a proximal seal to the fluid product, a distal seal to external contaminants, and an intermediate seal to the fluid product and to external contaminants between the proximal and distal seals.
摘要翻译：该阀包括一个阴部分，其具有封闭的，横向的近端壁，以及与凸缘部分成一体的管状壁，在该管状壁的近端部分上形成的侧向开口，近侧，具有开放横向近端的封闭/开口部分; 闭合/打开部分具有外部形状和外部尺寸，其适合阴部件的近侧接收部分的内部形状和内部尺寸。密封元件包括在轴向上彼此分离的三个环形密封件，由阳部件的管状壁的上表面支撑并与阴部件接合，与流体产品的近端密封件，对外部污染物的远端密封件以及对流体产品的中间密封和近端和远端密封之间的外部污染物。

4. 发明申请

US20140124504A1 THE CONNECTION OF AN ACCESSORY TO A RECEPTACLE 有权
标题翻译：附件与接收器的连接
公开(公告)号：US20140124504A1
公开(公告)日：2014-05-08
申请号：US14232722
申请日：2012-07-12
申请人： Frederic Bernard , Sebastien Chaussin , Jeremy Gibelin
发明人： Frederic Bernard , Sebastien Chaussin , Jeremy Gibelin
IPC分类号： B65D25/00
CPC分类号： B65D25/005 , A61J1/1475 , A61J1/2037 , A61J1/2051 , A61J1/2068 , A61J1/2093 , A61M39/18 , C12M23/46 , Y10T29/49826
摘要： The device (1) for the sealed connection to a receptacle (2) of an accessory (3), the active proximal part (9) of which is intended to be connected to the inside (4) of the receptacle (2) by an opening (7) in the receptacle (2), includes a first element (15), a second element (16) and a chamber (18), the first element (15) including a proximal end part (32) which is secured by sliding in the proximal direction, with insertion of a lateral sealing component (22), onto a matching part (19) of the receptacle (2), in the proximal direction, the transverse head (14) corresponding to the lower surface of the first element (15) and being provided with a lateral head sealing component (28) and the second element (16) being capable of being pre-assembled with the first element (15) by axial sliding in the proximal direction.
摘要翻译：用于与附件（3）的容器（2）的密封连接的装置（1），其主动近端部分（9）旨在通过一个或多个连接器（1）连接到容器（2）的内部（4）所述容器（2）中的开口（7）包括第一元件（15），第二元件（16）和腔室（18），所述第一元件（15）包括近端部分（32）沿着近端方向滑动，沿近端方向将横向密封部件（22）插入到接合器（2）的匹配部件（19）上，横向头部（14）对应于第一元件（15），并且设置有横向头部密封部件（28），并且第二元件（16）能够通过沿近端方向的轴向滑动而与第一元件（15）预组装。

5. 发明授权

US09440229B2 Leaktight joining device for the aseptic transfer of a biopharmaceutical product between a chamber and a container 有权
标题翻译：用于在室和容器之间无菌转移生物药物产品的泄漏接合装置
公开(公告)号：US09440229B2
公开(公告)日：2016-09-13
申请号：US14234788
申请日：2012-07-12
申请人： Gaelle Nodin , Jeremy Gibelin
发明人： Gaelle Nodin , Jeremy Gibelin
IPC分类号： B01L1/02 , G21F7/005 , C12M1/12
CPC分类号： B01L1/02 , C12M37/04 , G21F7/005
摘要： A leaktight joining device for ensuring the aseptic transfer of a biopharmaceutical product between a chamber equipped with a removable door and a container equipped with a removable cover, includes: stationary temporary flanging elements, stationary unlocking elements capable of changing the container from an initial locking position to an intermediate unlocking position so as to ensure an aseptic communication between the container and the chamber, stationary locking element capable of changing the container from the intermediate locking position to a final locking position, an annular functional ring gear capable of actuating the stationary unlocking elements and the stationary locking elements of the container. The stationary temporary flanging elements, the stationary unlocking elements, and the stationary locking elements are mechanically linked to the annular functional ring gear and arranged so that the unidirectional rotation of the annular functional ring gear about the geometric axis of rotation successively drives the actuation thereof.
摘要翻译：一种用于确保生物制药产品在装有可拆卸门的室与装有可移除盖的容器之间无菌转移的密封接合装置包括：固定的临时折边元件，能够将容器从初始锁定位置改变的固定解锁元件以确保容器和腔室之间的无菌连通，能够将容器从中间锁定位置改变到最终锁定位置的固定锁定元件，能够致动固定解锁元件的环形功能性环形齿轮和容器的固定锁定元件。固定的临时折边元件，固定解锁元件和固定锁定元件机械地连接到环形功能性环形齿轮并且被布置成使得环形功能性环形齿轮围绕旋转几何轴线的单向旋转连续地驱动其致动。

6. 发明授权

US09056695B2 Connection of an accessory to a receptacle 有权
标题翻译：将附件连接到插座
公开(公告)号：US09056695B2
公开(公告)日：2015-06-16
申请号：US14232722
申请日：2012-07-12
申请人： Frederic Bernard , Sebastien Chaussin , Jeremy Gibelin
发明人： Frederic Bernard , Sebastien Chaussin , Jeremy Gibelin
IPC分类号： B01L99/00 , B65D25/00 , A61M39/18 , C12M3/00 , A61J1/20 , A61J1/14
CPC分类号： B65D25/005 , A61J1/1475 , A61J1/2037 , A61J1/2051 , A61J1/2068 , A61J1/2093 , A61M39/18 , C12M23/46 , Y10T29/49826
摘要： The device (1) for the sealed connection to a receptacle (2) of an accessory (3), the active proximal part (9) of which is intended to be connected to the inside (4) of the receptacle (2) by an opening (7) in the receptacle (2), includes a first element (15), a second element (16) and a chamber (18), the first element (15) including a proximal end part (32) which is secured by sliding in the proximal direction, with insertion of a lateral sealing component (22), onto a matching part (19) of the receptacle (2), in the proximal direction, the transverse head (14) corresponding to the lower surface of the first element (15) and being provided with a lateral head sealing component (28) and the second element (16) being capable of being pre-assembled with the first element (15) by axial sliding in the proximal direction.
摘要翻译：用于与附件（3）的容器（2）的密封连接的装置（1），其主动近端部分（9）旨在通过一个或多个连接器（1）连接到容器（2）的内部（4）所述容器（2）中的开口（7）包括第一元件（15），第二元件（16）和腔室（18），所述第一元件（15）包括近端部分（32）沿着近端方向滑动，沿近端方向将横向密封部件（22）插入到接合器（2）的匹配部件（19）上，横向头部（14）对应于第一元件（15），并且设置有横向头部密封部件（28），并且第二元件（16）能够通过沿近端方向的轴向滑动而与第一元件（15）预组装。

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