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1. 发明授权

US09387343B2 Apparatus and method for effecting radiation treatment on a pre-selected anatomical portion of an animal body 有权
标题翻译：对动物体的预先选择的解剖部分进行放射治疗的装置和方法
公开(公告)号：US09387343B2
公开(公告)日：2016-07-12
申请号：US13367807
申请日：2012-02-07
申请人： Johann Kindlein , Arie Luite Visscher , Johan Henning , Wouter Peter Engels
发明人： Johann Kindlein , Arie Luite Visscher , Johan Henning , Wouter Peter Engels
IPC分类号： A61N5/10
CPC分类号： A61N5/1007 , A61N5/1075 , A61N2005/1008 , A61N2005/1012 , A61N2005/1094
摘要： A medical apparatus for effecting radiation treatment on a pre-selected anatomical portion of an animal body is disclosed. The medical apparatus may include a plurality of treatment channels configured to be positioned adjacent a body tissue and a plurality of delivery channels coupled to a corresponding number of treatment channels. The medical apparatus may also include a plurality of source channels configured to receive one or more energy sources, a tracking channel configured to receive a tracking element, and a connecting element configured to connect each delivery channel with either one of the plurality of sources channels or the tracking channel.
摘要翻译：公开了一种用于对动物体的预先选择的解剖部分进行放射治疗的医疗装置。医疗设备可以包括被配置为邻近身体组织定位的多个治疗通道以及耦合到相应数量的治疗通道的多个输送通道。医疗设备还可以包括被配置为接收一个或多个能量源的多个源通道，被配置为接收跟踪元件的跟踪通道，以及被配置为将每个输送通道与多个源通道中的任一个连接的连接元件跟踪通道。

2. 发明授权

US09370670B2 Gamma source tracking system 有权
标题翻译：伽马源跟踪系统
公开(公告)号：US09370670B2
公开(公告)日：2016-06-21
申请号：US14158568
申请日：2012-07-19
申请人： Johan Henning , Bas Woudstra , Jeroen Schuurman
发明人： Johan Henning , Bas Woudstra , Jeroen Schuurman
IPC分类号： G01T1/16 , A61N5/10 , G01T1/164
CPC分类号： A61N5/1001 , A61N5/1027 , A61N5/1048 , A61N2005/1052 , G01T1/1644
摘要： An embodiment of the present disclosure is directed to a radioactive source tracking system adapted to determine in real time a spatial position of a gamma source in a volume, including a set of spatially distributed position sensitive detectors operable in real time arranged about the volume. The system includes a real time computer system adapted to calculate the spatial position per time stamp of the gamma source in the volume based on respective signals generated by the position sensitive detectors. In addition, the radioactive source is represented by a 3D or 4D data stream in real time. Other embodiments of the present disclosure are directed to a method for tracking a radioactive gamma source and a computer program product for causing a processor to determine a real time 3D or a 4D spatial position of a gamma source.
摘要翻译：本公开的实施例涉及一种放射源跟踪系统，其适于实时地确定体积中的伽马源的空间位置，包括一组空间分布的位置敏感检测器，其可实时地布置在体积周围。该系统包括实时计算机系统，其适于基于由位置敏感检测器产生的相应信号计算体积中伽马源的每个时间戳的空间位置。此外，放射源由3D或4D数据流实时表示。本公开的其他实施例涉及用于跟踪放射性伽马源的方法和用于使处理器确定伽马源的实时3D或4D空间位置的计算机程序产品的方法。

3. 发明授权

US08520801B2 Mobile X-ray unit 有权
标题翻译：移动X射线单元
公开(公告)号：US08520801B2
公开(公告)日：2013-08-27
申请号：US13335414
申请日：2011-12-22
申请人： Johan Henning
发明人： Johan Henning
IPC分类号： A61N5/10
CPC分类号： A61N5/1083 , A61N5/1048 , A61N2005/005 , A61N2005/1091
摘要： One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base for accommodating a control unit, a power supply, and a cooler. The mobile X-ray unit further including an articulated arm associated with the base and coupled to an X-ray applicator. The X-ray applicator including an X-ray tube having an anode for generating an acceleration field and a target element for generating an X-ray beam, wherein a longitudinal axis of the anode is substantially parallel to a longitudinal axis of the X-ray tube.
摘要翻译：本公开的一个实施例涉及移动X射线单元。移动X射线单元可以包括用于容纳控制单元，电源和冷却器的基座。所述移动X射线单元还包括与所述基座相关联并且联接到X射线施加器的铰接臂。 X射线照射器包括具有用于产生加速场的阳极的X射线管和用于产生X射线束的目标元件，其中阳极的纵向轴线基本上平行于X射线的纵向轴线管。

4. 发明申请

US20120163540A1 MOBILE X-RAY UNIT 有权
标题翻译：移动X射线单元
公开(公告)号：US20120163540A1
公开(公告)日：2012-06-28
申请号：US13335830
申请日：2011-12-22
申请人： Johannes Simon van der Veen , Bas Woudstra , Johan Henning
发明人： Johannes Simon van der Veen , Bas Woudstra , Johan Henning
IPC分类号： A61N5/10
CPC分类号： A61B6/542 , A61B6/4423 , A61N5/1048 , A61N5/1071 , A61N2005/1076 , A61N2005/1091
摘要： One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base for accommodating a control unit configured to control an X-ray applicator and a power supply configured to supply power to the X-ray applicator. The mobile X-ray unit may further include an articulated arm associated with the base. The arm may be configured to support the X-ray applicator. The X-ray applicator may have an X-ray tube for emitting an X-ray beam for irradiating an object. The mobile X-ray unit may further include a phantom-based dosimetry system configured to perform a dosimetry check of the X-ray beam.
摘要翻译：本公开的一个实施例涉及移动X射线单元。移动X射线单元可以包括用于容纳被配置为控制X射线施加器的控制单元的基座和被配置为向X射线施加器供电的电源。移动X射线单元还可以包括与基座相关联的关节臂。臂可以被配置为支撑X射线施加器。 X射线投射器可以具有用于发射用于照射物体的X射线束的X射线管。移动X射线单元还可以包括被配置为执行X射线束的剂量测定检查的基于幻像的剂量测定系统。

5. 发明授权

US08995616B2 Mobile X-ray unit 有权
标题翻译：移动X射线单元
公开(公告)号：US08995616B2
公开(公告)日：2015-03-31
申请号：US13335712
申请日：2011-12-22
申请人： Johannes Simon van der Veen , Bas Woudstra , Johan Henning
发明人： Johannes Simon van der Veen , Bas Woudstra , Johan Henning
IPC分类号： A61N5/10 , H05G1/28 , A61N5/00 , H01J35/00
CPC分类号： A61N5/1071 , A61B6/08 , A61N5/1048 , A61N5/1049 , A61N5/1075 , A61N5/1083 , A61N2005/005 , A61N2005/105 , A61N2005/1056 , A61N2005/1091 , H01J35/00 , H01J35/02 , H01J35/16 , H01J35/32 , H05G1/04
摘要： One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base for accommodating a control unit for controlling an X-ray applicator and a power supply for supplying power to the X-ray applicator. The mobile X-ray unit may further include an articulated arm associated with the base and coupled to the X-ray applicator. The X-ray applicator may have an X-ray tube configured to emit an X-ray beam through an exit window to irradiate an object. The mobile X-ray unit may further include a dosimetry system adapted for real time dosimetry.
摘要翻译：本公开的一个实施例涉及移动X射线单元。移动X射线单元可以包括用于容纳用于控制X射线施加器的控制单元的基座和用于向X射线施加器供电的电源。移动X射线单元还可以包括与基座相关联并且联接到X射线施加器的铰接臂。 X射线施加器可以具有被配置为通过出射窗口发射X射线束以照射物体的X射线管。移动X射线单元还可以包括适于实时剂量测定的剂量测定系统。

6. 发明申请

US20120163556A1 Mobile X-Ray Unit 有权
标题翻译：移动X射线单元
公开(公告)号：US20120163556A1
公开(公告)日：2012-06-28
申请号：US13335152
申请日：2011-12-22
申请人： Johan Henning , Bas Woudstra
发明人： Johan Henning , Bas Woudstra
IPC分类号： H05G1/02 , A61B6/08
CPC分类号： A61N5/1049 , A61N5/1083 , A61N2005/1056 , A61N2005/1091
摘要： One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base having a control unit and a power supply. The mobile X-ray unit may further include an articulated arm associated with the base. The articulated arm may be coupled to an X-ray applicator having an X-ray tube. The X-ray tube may include a target for generating an X-ray beam, a collimator for shaping the X-ray beam, and an exit surface through which the X-ray beam is configured to exit the X-ray tube. The mobile X-ray unit may have at least one light source configured to illuminate at least a portion of the X-ray beam emitted from the exit surface.
摘要翻译：本公开的一个实施例涉及移动X射线单元。移动X射线单元可以包括具有控制单元和电源的基座。移动X射线单元还可以包括与基座相关联的关节臂。关节臂可以联接到具有X射线管的X射线施加器。 X射线管可以包括用于产生X射线束的靶，用于成形X射线束的准直器以及X射线束被配置为离开X射线管的出射表面。移动X射线单元可以具有被配置为照射从出射表面发射的X射线束的至少一部分的至少一个光源。

7. 发明申请

US20120163539A1 MOBILE X-RAY UNIT 有权
标题翻译：移动X射线单元
公开(公告)号：US20120163539A1
公开(公告)日：2012-06-28
申请号：US13335712
申请日：2011-12-22
申请人： Johannes Simon van der VEEN , Bas Woudstra , Johan Henning
发明人： Johannes Simon van der VEEN , Bas Woudstra , Johan Henning
IPC分类号： A61N5/10
CPC分类号： A61N5/1071 , A61B6/08 , A61N5/1048 , A61N5/1049 , A61N5/1075 , A61N5/1083 , A61N2005/005 , A61N2005/105 , A61N2005/1056 , A61N2005/1091 , H01J35/00 , H01J35/02 , H01J35/16 , H01J35/32 , H05G1/04
摘要： One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base for accommodating a control unit for controlling an X-ray applicator and a power supply for supplying power to the X-ray applicator. The mobile X-ray unit may further include an articulated arm associated with the base and coupled to the X-ray applicator. The X-ray applicator may have an X-ray tube configured to emit an X-ray beam through an exit window to irradiate an object. The mobile X-ray unit may further include a dosimetry system adapted for real time dosimetry.
摘要翻译：本公开的一个实施例涉及移动X射线单元。移动X射线单元可以包括用于容纳用于控制X射线施加器的控制单元的基座和用于向X射线施加器供电的电源。移动X射线单元还可以包括与基座相关联并且联接到X射线施加器的铰接臂。 X射线施加器可以具有被配置为通过出射窗口发射X射线束以照射物体的X射线管。移动X射线单元还可以包括适于实时剂量测定的剂量测定系统。

8. 发明授权

US09730608B2 Method and apparatus for determining the position of a surgical tool relative to a target volume inside an animal body 有权
公开(公告)号：US09730608B2
公开(公告)日：2017-08-15
申请号：US13347225
申请日：2012-01-10
申请人： Wilco Van Der Lugt , Jeroen Schuurman , Johan Henning , Stefan Kwa , Johann Kindlein
发明人： Wilco Van Der Lugt , Jeroen Schuurman , Johan Henning , Stefan Kwa , Johann Kindlein
IPC分类号： A61B8/00 , A61B5/055 , G06T11/00 , A61B6/06 , A61B8/12 , A61B17/00 , A61B18/00 , A61N5/10 , A61B8/08 , A61B90/00
CPC分类号： A61B5/055 , A61B6/06 , A61B8/12 , A61B8/4461 , A61B8/483 , A61B90/36 , A61B2017/00274 , A61B2018/00547 , A61N5/1027 , A61N5/1049 , A61N2005/1011 , G06T11/008 , G06T2211/428
摘要： The invention relates to a method for determining the position of a surgical tool relative to a target volume inside an animal body according to a pre-plan comprising the steps of i) obtaining a plurality of two-dimensional images of said target volume using imaging means, each 2D-image being represented by an image data slice I(x,y,z); ii) reconstructing from said plurality of image data slices I(x,y,z) a three-dimensional image of said target volume using transformation means, said 3D-image being represented by a volumetric image data array V(x,y,z); iii) displaying said three-dimensional image of said target volume to an user using displaying means.

9. 发明授权

US08105238B2 Method and apparatus for determining the position of a surgical tool relative to a target volume inside an animal body 有权
标题翻译：用于确定外科手术工具相对于动物体内目标体积的位置的方法和装置
公开(公告)号：US08105238B2
公开(公告)日：2012-01-31
申请号：US10921896
申请日：2004-08-20
申请人： Wilco Van Der Lugt , Jeroen Schuurman , Johan Henning , Stefan Kwa , Johann Kindlein
发明人： Wilco Van Der Lugt , Jeroen Schuurman , Johan Henning , Stefan Kwa , Johann Kindlein
IPC分类号： A61B8/00
CPC分类号： A61B5/055 , A61B6/06 , A61B8/12 , A61B8/4461 , A61B8/483 , A61B90/36 , A61B2017/00274 , A61B2018/00547 , A61N5/1027 , A61N5/1049 , A61N2005/1011 , G06T11/008 , G06T2211/428
摘要： A method for determining the position of a surgical tool relative to a target volume inside an animal body according to a pre-plan. The method includes the steps of i) obtaining a plurality of two-dimensional images of said target volume using an imaging device, each 2D-image being represented by an image data slice I(x,y,z); ii) reconstructing from said plurality of image data slices I(x,y,z) a three-dimensional image of said target volume using a transformation device, said 3D-image being represented by a volumetric image data array V(x,y,z); iii) displaying said three-dimensional image of said target volume to an user using a display.
摘要翻译：根据预先计划确定外科手术工具相对于动物体内目标体积的位置的方法。该方法包括以下步骤：i）使用成像装置获得所述目标体积的多个二维图像，每个2D图像由图像数据切片I（x，y，z）表示; ii）使用变换装置从所述多个图像数据切片I（x，y，z）重建所述目标体积的三维图像，所述3D图像由体积图像数据阵列V（x，y， z）; iii）使用显示器将所述目标体积的所述三维图像显示给用户。

10. 发明申请

US20070038205A1 Apparatus and method for effecting radiation treatment on a pre-selected anatomical portion of an animal body 有权
标题翻译：对动物体的预先选择的解剖部分进行放射治疗的装置和方法
公开(公告)号：US20070038205A1
公开(公告)日：2007-02-15
申请号：US11487303
申请日：2006-07-17
申请人： Johann Kindlein , Arie Visscher , Johan Henning , Wouter Engels
发明人： Johann Kindlein , Arie Visscher , Johan Henning , Wouter Engels
IPC分类号： A61B18/18
CPC分类号： A61N5/1007 , A61N5/1075 , A61N2005/1008 , A61N2005/1012 , A61N2005/1094
摘要： The invention relates to an apparatus for effecting radiation treatment on a pre-selected anatomical portion of an animal body comprising: a group of n hollow treatment channels being inserted at one or more pre-planned positions in said pre-selected anatomical portion; a group of m delivery channels to be connected to a corresponding number m from said group of n hollow treatment channels with m being 2 or more and n being 1 or more; identifying means for identifying which one of said m delivery channels is being connected with which one of said n hollow treatment channels, said identifying means comprising a tracking element accommodated in a tracking channel, said tracking element being intended to be displaced from said tracking channel through each of said interconnected m delivery channels and m treatment channels; storage means for storing k energy emitting sources in a corresponding source-channel, with k≦m; delivery means for temporarily inserting said k energy emitting sources from their source-channels through a corresponding one of said interconnected m delivery channels and m treatment channels towards one of said pre-planned positions in said anatomical portion; coupling means for coupling at least one of said m delivery channels with a corresponding treatment channel.
摘要翻译：本发明涉及一种用于对动物体的预先选择的解剖部分进行辐射治疗的装置，包括：一组n个中空治疗通道，其插入在所述预先选择的解剖部分中的一个或多个预先计划的位置; 一组m个传送通道，其与m个为2个以上且n为1以上的n个中空处理通道组相对应的m个连接; 用于识别所述m个输送通道中的哪一个正在与所述n个中空治疗通道中的一个连接的所述识别装置，所述识别装置包括容纳在跟踪通道中的跟踪元件，所述跟踪元件旨在从所述跟踪通道移位通过每个所述相互连接的输送通道和m个治疗通道; 存储装置，用于将k个能量发射源存储在相应的源信道中，k <= m; 递送装置，用于将所述k个能量发射源从其源通道中通过所述互连的m个输送通道和m个治疗通道中的相应一个朝向所述解剖部分中的所述预先计划的位置之一插入; 用于将所述m个输送通道中的至少一个与相应的治疗通道联接的联接装置。

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