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1. 发明申请

US20120165902A1 MULTI-ELECTRODE IMPLANTABLE SYSTEMS AND ASSEMBLIES THEREOF 有权
标题翻译：多电极可植入系统及其组合
公开(公告)号：US20120165902A1
公开(公告)日：2012-06-28
申请号：US13008524
申请日：2011-01-18
申请人： John Louis Sommer , Joseph Michael D'Sa , Joyce K. Yamamoto , Brad C. Tischendorf , James D. Reinke , Andrew J. Thom , Thomas P. Miltich , William John Taylor , Kenneth C. Gardeski , Larry Earl Tyler , Jeffrey O. York , Gordon O. Munns
发明人： John Louis Sommer , Joseph Michael D'Sa , Joyce K. Yamamoto , Brad C. Tischendorf , James D. Reinke , Andrew J. Thom , Thomas P. Miltich , William John Taylor , Kenneth C. Gardeski , Larry Earl Tyler , Jeffrey O. York , Gordon O. Munns
IPC分类号： A61N1/36
CPC分类号： A61N1/362 , A61N1/05 , A61N1/056 , A61N1/372
摘要： Hermetically sealed assemblies, for example, that include IC chips, are configured for incorporation within a connector terminal of an implantable medical electrical lead, preferably within a contact member of the terminal. An assembly may include two feedthrough subassemblies, welded to either end of the contact member, to form an hermetic capsule, in which an IC chip is enclosed, and a tubular member, which allows a lumen to extend therethrough, along a length of the terminal. A multi-electrode lead may include multiplexer circuitry, preferably a switch matrix element and a communications, control and power supply element that are electrically coupled to the contact member and to another contact member of the terminal. Each pair of switch matrix switches allows for any two of the electrodes to be selected, in order to deliver a stimulation vector, via stimulation pulses from a device/pulse generator, to which the connector terminal is connected.
摘要翻译：例如，包括IC芯片的密封组件被配置为并入可植入医疗电线的连接器端子内，优选地在端子的接触构件内。组件可以包括焊接到接触构件的任一端的两个馈通子组件，以形成封闭IC芯片的密封胶囊，以及允许内腔沿着端子的长度延伸穿过的管状构件。多电极引线可以包括多路复用器电路，优选地是开关矩阵元件和通信，控制和电源元件，其电耦合到接触构件和终端的另一接触构件。每对开关矩阵开关允许选择任何两个电极，以便通过连接器端子连接到的装置/脉冲发生器的刺激脉冲传送刺激矢量。

2. 发明申请

US20100298901A1 IMPLANTABLE MEDICAL DEVICE FOR CARDIAC ELECTRICAL STIMULATION 审中-公开
标题翻译：用于心脏电刺激的可植入医疗装置
公开(公告)号：US20100298901A1
公开(公告)日：2010-11-25
申请号：US12771217
申请日：2010-04-30
申请人： John Louis Sommer , Scott J. Brabec , Jon Frederic Urban , Yong-Fu Xiao , Xiaohong Zhou
发明人： John Louis Sommer , Scott J. Brabec , Jon Frederic Urban , Yong-Fu Xiao , Xiaohong Zhou
IPC分类号： A61N1/362 , A61N1/36
CPC分类号： A61N1/3621 , A61B5/0215 , A61B5/024 , A61B5/02405 , A61B5/0452 , A61B5/0456 , A61N1/3627 , A61N1/3702
摘要： A method and apparatus for reducing a patient's heart rate or blood pressure. The apparatus provides stimulation to the patient's atrial and/or nodal tissue within the associated refractory period of the ventricle but outside of an associated refractory period of the stimulated atrial an/or nodal tissue, responsive to detecting an occurrence of a ventricular depolarization following a preceding atrial depolarization.The apparatus may define a time window following the ventricular depolarization, following the atrial depolarization or determined based upon the timing of both the atrial and ventricular depolarizations. The stimulus may be delivered during or on expiration of the defined time window. The duration of the time window may be pre-set or determined based upon measurements of the patient's refractory periods.
摘要翻译：一种减轻患者心率或血压的方法和装置。该装置响应于检测在前面的心室去极化的发生之后，在心室的相关不应期内但在受刺激的心房和/或淋巴结组织的相关不应期之外对患者的心房和/或淋巴结组织提供刺激。心房去极化。该装置可以在心房去极化之后定义心室去极化之后的时间窗口，或者基于心房和心室去极化的时间确定。刺激可以在定义的时间窗口期间或期满时传送。时间窗口的持续时间可以基于患者的不应期的测量来预先确定或确定。

3. 发明申请

US20110077725A1 MEDICAL ELECTRICAL LEAD 有权
标题翻译：医用电线
公开(公告)号：US20110077725A1
公开(公告)日：2011-03-31
申请号：US12570365
申请日：2009-09-30
申请人： John Louis Sommer , Jon D. Schell
发明人： John Louis Sommer , Jon D. Schell
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0563 , A61N2001/0585
摘要： An implantable lead for placement by means of a guide wire passing therethrough. The lead has an elongated insulative lead body with an axially extending lumen through at least a distal portion of the lead body. A conductor is mounted within and extends to an electrode assembly mounted to a distal portion of the lead body. A seal housing with a seal located therein located at a distal end of the lead body. The seal is located generally perpendicular to the axis of the lead body and is concave on both its proximal and distal sides. The housing is provided with a cavity adjacent each of the seal's proximal and distal sides, into which the seal may be deflected. The electrode assembly may be mounted to the seal housing.
摘要翻译：一种用于通过导丝穿过其进行放置的可植入引线。引线具有细长的绝缘引线体，其具有穿过引线本体的至少远端部分的轴向延伸的内腔。导体安装在安装到引线主体的远端部分的电极组件内并延伸到导线主体的远端部分。密封壳体，其中位于引线主体的远端处的位于其中的密封件。密封件大致垂直于引线主体的轴线定位并且在其近侧和远侧都是凹入的。壳体设置有与密封件的近侧和远侧相邻的空腔，密封件可以偏转到其中。电极组件可以安装到密封壳体。

4. 发明授权

US09333341B2 Medical electrical lead 有权
标题翻译：医用电线
公开(公告)号：US09333341B2
公开(公告)日：2016-05-10
申请号：US12570365
申请日：2009-09-30
申请人： John Louis Sommer , Jon D. Schell
发明人： John Louis Sommer , Jon D. Schell
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0563 , A61N2001/0585
摘要： An implantable lead for placement by means of a guide wire passing therethrough. The lead has an elongated insulative lead body with an axially extending lumen through at least a distal portion of the lead body. A conductor is mounted within and extends to an electrode assembly mounted to a distal portion of the lead body. A seal housing with a seal located therein located at a distal end of the lead body. The seal is located generally perpendicular to the axis of the lead body and is concave on both its proximal and distal sides. The housing is provided with a cavity adjacent each of the seal's proximal and distal sides, into which the seal may be deflected. The electrode assembly may be mounted to the seal housing.
摘要翻译：一种用于通过导丝穿过其进行放置的可植入引线。引线具有细长的绝缘引线体，其具有穿过引线本体的至少远端部分的轴向延伸的内腔。导体安装在安装到引线主体的远端部分的电极组件内并延伸到导线主体的远端部分。密封壳体，其中位于引线主体的远端处的位于其中的密封件。密封件大致垂直于引线主体的轴线定位并且在其近侧和远侧都是凹入的。壳体设置有与密封件的近侧和远侧相邻的空腔，密封件可以偏转到其中。电极组件可以安装到密封壳体。

5. 发明授权

US08332045B2 System and method for cardiac lead switching 有权
标题翻译：心脏导联切换的系统和方法
公开(公告)号：US08332045B2
公开(公告)日：2012-12-11
申请号：US12363327
申请日：2009-01-30
申请人： John Louis Sommer , Michael William Kimmel , Yong Kyun Cho
发明人： John Louis Sommer , Michael William Kimmel , Yong Kyun Cho
IPC分类号： A61N1/00
CPC分类号： A61N1/37 , A61N1/056 , A61N1/086 , A61N1/3718
摘要： An implantable medical device (IMD) can include an implantable pulse generator (IPG), such as a cardiac pacemaker or an implantable cardioverter-defibrillator (ICD). Various portions of the IMD, such as a device body, a lead body, or a lead tip, can be provided to reduce or dissipate a current and heat induced by various external environmental factors. According to various embodiments, features can be incorporated into the lead body, the lead tip, or the IMD body to reduce the creation of an induced current, or dissipate the induced current and heat created due to an induced current in the lead.
摘要翻译：可植入医疗装置（IMD）可以包括可植入脉冲发生器（IPG），例如心脏起搏器或植入式心律转复除颤器（ICD）。可以提供IMD的各个部分，例如装置主体，引线主体或引线头，以减少或消散由各种外部环境因素引起的电流和热量。根据各种实施例，可以将特征结合到引线体，引线尖端或IMD体中，以减少感应电流的产生，或者消散由于引线中的感应电流而产生的感应电流和热量。

6. 发明申请

US20100198311A1 SYSTEM AND METHOD FOR CARDIAC LEAD SWITCHING 审中-公开
标题翻译：用于心脏导管切换的系统和方法
公开(公告)号：US20100198311A1
公开(公告)日：2010-08-05
申请号：US12363321
申请日：2009-01-30
申请人： John Louis SOMMER , Michael William KIMMEL , Yong Kyun CHO
发明人： John Louis SOMMER , Michael William KIMMEL , Yong Kyun CHO
IPC分类号： A61N1/08
CPC分类号： A61N1/37 , A61N1/056 , A61N1/086 , A61N1/3718
摘要： An implantable medical device (IMD) can include an implantable pulse generator (IPG), such as a cardiac pacemaker or an implantable cardioverter-defibrillator (ICD). Various portions of the IMD, such as a device body, a lead body, or a lead tip, can be provided to reduce or dissipate a current and heat induced by various external environmental factors. According to various embodiments, features can be incorporated into the lead body, the lead tip, or the IMD body to reduce the creation of an induced current, or dissipate the induced current and heat created due to an induced current in the lead.
摘要翻译：可植入医疗装置（IMD）可以包括可植入脉冲发生器（IPG），例如心脏起搏器或植入式心律转复除颤器（ICD）。可以提供IMD的各个部分，例如装置主体，引线主体或引线头，以减少或消散由各种外部环境因素引起的电流和热量。根据各种实施例，可以将特征结合到引线体，引线尖端或IMD体中，以减少感应电流的产生，或者消散由于引线中的感应电流而产生的感应电流和热量。

7. 发明授权

US08509899B2 Multi-electrode implantable systems and assemblies thereof 有权
标题翻译：多电极可植入系统及其组件
公开(公告)号：US08509899B2
公开(公告)日：2013-08-13
申请号：US13008524
申请日：2011-01-18
申请人： John Louis Sommer , Joseph Michael D'Sa , Joyce K. Yamamoto , Brad C. Tischendorf , James D. Reinke , Andrew J. Thom , Thomas P. Miltich , William John Taylor , Kenneth C. Gardeski , Larry Earl Tyler , Jeffrey O. York , Gordon O. Munns
发明人： John Louis Sommer , Joseph Michael D'Sa , Joyce K. Yamamoto , Brad C. Tischendorf , James D. Reinke , Andrew J. Thom , Thomas P. Miltich , William John Taylor , Kenneth C. Gardeski , Larry Earl Tyler , Jeffrey O. York , Gordon O. Munns
IPC分类号： A61N1/362
CPC分类号： A61N1/362 , A61N1/05 , A61N1/056 , A61N1/372
摘要： Hermetically sealed assemblies, for example, that include IC chips, are configured for incorporation within a connector terminal of an implantable medical electrical lead, preferably within a contact member of the terminal. An assembly may include two feedthrough subassemblies, welded to either end of the contact member, to form an hermetic capsule, in which an IC chip is enclosed, and a tubular member, which allows a lumen to extend therethrough, along a length of the terminal. A multi-electrode lead may include multiplexer circuitry, preferably a switch matrix element and a communications, control and power supply element that are electrically coupled to the contact member and to another contact member of the terminal. Each pair of switch matrix switches allows for any two of the electrodes to be selected, in order to deliver a stimulation vector, via stimulation pulses from a device/pulse generator, to which the connector terminal is connected.
摘要翻译：例如，包括IC芯片的密封组件被配置为并入可植入医疗电线的连接器端子内，优选地在端子的接触构件内。组件可以包括焊接到接触构件的任一端的两个馈通子组件，以形成封闭IC芯片的密封胶囊，以及允许内腔沿着端子的长度延伸穿过的管状构件。多电极引线可以包括多路复用器电路，优选地是开关矩阵元件和通信，控制和电源元件，其电耦合到接触构件和终端的另一接触构件。每对开关矩阵开关允许选择任何两个电极，以便通过来自连接器端子连接到的装置/脉冲发生器的刺激脉冲传送刺激矢量。

8. 发明申请

US20090234405A1 SYSTEM AND METHOD FOR CARDIAC LEAD SWITCHING 有权
标题翻译：用于心脏导管切换的系统和方法
公开(公告)号：US20090234405A1
公开(公告)日：2009-09-17
申请号：US12363327
申请日：2009-01-30
申请人： John Louis SOMMER , Michael William KIMMEL , Yong Kyun CHO
发明人： John Louis SOMMER , Michael William KIMMEL , Yong Kyun CHO
IPC分类号： A61N1/362 , A61N1/00
CPC分类号： A61N1/37 , A61N1/056 , A61N1/086 , A61N1/3718
摘要： An implantable medical device (IMD) can include an implantable pulse generator (IPG), such as a cardiac pacemaker or an implantable cardioverter-defibrillator (ICD). Various portions of the IMD, such as a device body, a lead body, or a lead tip, can be provided to reduce or dissipate a current and heat induced by various external environmental factors. According to various embodiments, features can be incorporated into the lead body, the lead tip, or the IMD body to reduce the creation of an induced current, or dissipate the induced current and heat created due to an induced current in the lead.
摘要翻译：可植入医疗装置（IMD）可以包括可植入脉冲发生器（IPG），例如心脏起搏器或植入式心律转复除颤器（ICD）。可以提供IMD的各个部分，例如装置主体，引线主体或引线头，以减少或消散由各种外部环境因素引起的电流和热量。根据各种实施例，可以将特征结合到引线体，引线尖端或IMD体中，以减少感应电流的产生，或者消散由于引线中的感应电流而产生的感应电流和热量。

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