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1. 发明申请

US20120165902A1 MULTI-ELECTRODE IMPLANTABLE SYSTEMS AND ASSEMBLIES THEREOF 有权
标题翻译：多电极可植入系统及其组合
公开(公告)号：US20120165902A1
公开(公告)日：2012-06-28
申请号：US13008524
申请日：2011-01-18
申请人： John Louis Sommer , Joseph Michael D'Sa , Joyce K. Yamamoto , Brad C. Tischendorf , James D. Reinke , Andrew J. Thom , Thomas P. Miltich , William John Taylor , Kenneth C. Gardeski , Larry Earl Tyler , Jeffrey O. York , Gordon O. Munns
发明人： John Louis Sommer , Joseph Michael D'Sa , Joyce K. Yamamoto , Brad C. Tischendorf , James D. Reinke , Andrew J. Thom , Thomas P. Miltich , William John Taylor , Kenneth C. Gardeski , Larry Earl Tyler , Jeffrey O. York , Gordon O. Munns
IPC分类号： A61N1/36
CPC分类号： A61N1/362 , A61N1/05 , A61N1/056 , A61N1/372
摘要： Hermetically sealed assemblies, for example, that include IC chips, are configured for incorporation within a connector terminal of an implantable medical electrical lead, preferably within a contact member of the terminal. An assembly may include two feedthrough subassemblies, welded to either end of the contact member, to form an hermetic capsule, in which an IC chip is enclosed, and a tubular member, which allows a lumen to extend therethrough, along a length of the terminal. A multi-electrode lead may include multiplexer circuitry, preferably a switch matrix element and a communications, control and power supply element that are electrically coupled to the contact member and to another contact member of the terminal. Each pair of switch matrix switches allows for any two of the electrodes to be selected, in order to deliver a stimulation vector, via stimulation pulses from a device/pulse generator, to which the connector terminal is connected.
摘要翻译：例如，包括IC芯片的密封组件被配置为并入可植入医疗电线的连接器端子内，优选地在端子的接触构件内。组件可以包括焊接到接触构件的任一端的两个馈通子组件，以形成封闭IC芯片的密封胶囊，以及允许内腔沿着端子的长度延伸穿过的管状构件。多电极引线可以包括多路复用器电路，优选地是开关矩阵元件和通信，控制和电源元件，其电耦合到接触构件和终端的另一接触构件。每对开关矩阵开关允许选择任何两个电极，以便通过连接器端子连接到的装置/脉冲发生器的刺激脉冲传送刺激矢量。

2. 发明申请

US20110201921A1 Therapy Delivery System Including a Navigation Element 审中-公开
标题翻译：包括导航元素的治疗传递系统
公开(公告)号：US20110201921A1
公开(公告)日：2011-08-18
申请号：US13095085
申请日：2011-04-27
申请人： Michael R. Neidert , Kenneth C. Gardeski , Johnson E. Goode , Mark D. Schneider
发明人： Michael R. Neidert , Kenneth C. Gardeski , Johnson E. Goode , Mark D. Schneider
IPC分类号： A61B5/055
CPC分类号： A61B19/5244 , A61B5/0084 , A61B5/055 , A61B5/6852 , A61B10/04 , A61B17/1214 , A61B17/3478 , A61B18/1492 , A61B18/18 , A61B34/20 , A61B34/25 , A61B90/36 , A61B90/39 , A61B2018/00071 , A61B2018/00839 , A61B2034/2051 , A61B2090/3958
摘要： An electromagnetic receiver assembly is included in a navigation element for a therapy delivery system. If the system is modular, the navigation element may be an insertable module thereof and/or include a lumen to receive another insertable module.
摘要翻译：用于治疗传送系统的导航元件中包括电磁接收器组件。如果系统是模块化的，则导航元件可以是其可插入模块和/或包括用于接收另一可插入模块的内腔。

3. 发明授权

US07758521B2 Methods and systems for accessing the pericardial space 有权
标题翻译：用于获取心包空间的方法和系统
公开(公告)号：US07758521B2
公开(公告)日：2010-07-20
申请号：US11000539
申请日：2004-12-01
申请人： Mary M Morris , Kenneth C. Gardeski , Michael R. Ujhelyi , Michael E. Leckrone
发明人： Mary M Morris , Kenneth C. Gardeski , Michael R. Ujhelyi , Michael E. Leckrone
IPC分类号： A61M25/00 , A61M25/01
CPC分类号： A61B17/3478 , A61B17/00234 , A61B17/3417 , A61B18/1492 , A61B2017/00247 , A61B2017/003 , A61B2017/22077 , A61B2017/3484 , A61B2017/3488 , A61B2017/349 , A61B2018/00291 , A61B2018/00357 , A61B2018/00392 , A61M25/0084 , A61M2025/0037
摘要： Methods and systems for transvenously accessing the pericardial space via the vascular system and atrial wall, particularly through the superior vena cava and right atrial wall, to deliver treatment in the pericardial space are disclosed. A steerable instrument is advanced transvenously into the right atrium of the heart, and a distal segment is deflected into the right atrial appendage. A fixation catheter is advanced employing the steerable instrument to affix a distal fixation mechanism to the atrial wall. A distal segment of an elongated medical device, e.g., a therapeutic catheter or an electrical medical lead, is advanced through the fixation catheter lumen, through the atrial wall, and into the pericardial space. The steerable guide catheter is removed, and the elongated medical device is coupled to an implantable medical device subcutaneously implanted in the thoracic region. The fixation catheter may be left in place.
摘要翻译：公开了通过血管系统和心房壁，特别是通过上腔静脉和右心房壁经心脏进入心包空间的方法和系统，以在心包空间中递送治疗。一个可操纵的器械被递送到心脏的右心房，远端部分被偏转到右心耳。使用可操纵的器械来前进固定导管，以将远端固定机构固定在心房壁上。细长医疗装置（例如治疗性导管或电气医用引线）的远端部分通过固定导管内腔前进通过心房壁并进入心包空间。可移动的导向导管被移除，并且细长的医疗装置被联接到皮下植入胸部区域的可植入医疗装置。固定导管可以留在原位。

4. 发明申请

US20090276022A1 TECHNIQUES FOR PLACING MEDICAL LEADS FOR ELECTRICAL STIMULATION OF NERVE TISSUE 审中-公开
公开(公告)号：US20090276022A1
公开(公告)日：2009-11-05
申请号：US12433773
申请日：2009-04-30
申请人： John E. Burnes , Kenneth C. Gardeski , Ruth N. Klepfer , Patrick E. Macaulay , Mary M. Morris , Avram Scheiner
发明人： John E. Burnes , Kenneth C. Gardeski , Ruth N. Klepfer , Patrick E. Macaulay , Mary M. Morris , Avram Scheiner
IPC分类号： A61N1/05
CPC分类号： A61N1/36053 , A61M25/09 , A61N1/05 , A61N1/0551 , A61N1/0558 , A61N1/057 , A61N1/36085 , A61N1/36114 , A61N1/36125 , A61N1/36128
摘要： This disclosure is directed to extra, intra, and transvascular medical lead placement techniques for arranging medical leads and electrical stimulation and/or sensing electrodes proximate nerve tissue within a patient.

5. 发明申请

US20090264862A1 MEDICAL DELIVERY DEVICE CONSTRUCTION 有权
标题翻译：医疗设备施工
公开(公告)号：US20090264862A1
公开(公告)日：2009-10-22
申请号：US12424100
申请日：2009-04-15
申请人： Michael R. Neidert , Kenneth C. Gardeski
发明人： Michael R. Neidert , Kenneth C. Gardeski
IPC分类号： A61M25/14
CPC分类号： A61M25/0021 , A61M25/0023
摘要： A delivery device includes an outer sidewall and an inner sidewall extending therein. An outer surface of the inner sidewall defines a plurality of longitudinally extending grooves, each of which interlock with a corresponding inward protruding member of a plurality of longitudinally extending inward protruding members defined by an inner surface of the outer sidewall. A longitudinally extending lumen of the device, which may accommodate delivery of an implantable medical device, is defined, at least in part, by the inner surface of the inner sidewall. A slitting zone of the device, for example, provided by one of the sidewalls extending less than 360 degrees about a longitudinal axis of the device, enables removal of the delivery device from around the delivered device.
摘要翻译：输送装置包括外侧壁和在其中延伸的内侧壁。内侧壁的外表面限定多个纵向延伸的槽，每个槽与由外侧壁的内表面限定的多个纵向延伸的向内突出构件的相应向内突出构件互锁。至少部分地由内侧壁的内表面限定可容纳可植入医疗装置的输送的装置的纵向延伸的内腔。例如，由围绕装置的纵向轴线延伸小于360度的侧壁之一提供的装置的切割区域使得能够从输送装置周围移除输送装置。

6. 发明授权

US06697677B2 System and method for placing a medical electrical lead 有权
标题翻译：放置医用电线的系统和方法
公开(公告)号：US06697677B2
公开(公告)日：2004-02-24
申请号：US09826730
申请日：2001-04-05
申请人： Roger Dahl , Brad D. Pedersen , Duane Zytkovicz , Kenneth C. Gardeski
发明人： Roger Dahl , Brad D. Pedersen , Duane Zytkovicz , Kenneth C. Gardeski
IPC分类号： A61N105
CPC分类号： A61N1/056 , A61N2001/0578 , A61N2001/058 , A61N2001/0585
摘要： An improved system and method that is capable of delivering multiple electrode assemblies to predetermined implant sites within a body is disclosed. The system includes an elongated member such as an introducer sheath. The introducer includes an elongated channel along at least a distal end portion of the introducer. The elongated channel opens to the exterior surface of the introducer through an elongated slot. One or more electrode assemblies may be retained within the elongated channel such that the leads exit the introducer via the elongated slot. The elongated introducer further includes a lumen that is in fluid communication with channel through openings, or gaps. The electrode assemblies are loaded within the channel at predetermined positions with respect to the openings. A distal end of a stiffening member such as a stylet may then be advanced within the lumen and through a selected one of the openings to engage an electrode assembly. The distal end of the stylet, along with the electrode assembly, is pushed in a distal direction within the channel until the electrode assembly exits the channel at a predetermined implant site. The stylet is then de-coupled from the electrode assembly, and the distal end is again retracted into the lumen. The distal end of the stiffening member may be re-directed into a different opening to engage a second electrode assembly. After the introducer is repositioned at a second implant site, the second electrode assembly may be deployed in a manner similar to that discussed above. The process may be repeated to deploy an array of electrodes. According to one aspect of the invention, the stylet distal end is canted to extend from the lumen of the introducer into the channel.
摘要翻译：公开了能够将多个电极组件递送到体内预定植入部位的改进的系统和方法。该系统包括细长构件，例如导引器护套。导引器包括沿导引器的至少远端部分的细长通道。细长通道通过细长的槽向导引器的外表面开口。一个或多个电极组件可以保持在细长通道内，使得引线经由细长槽离开导引器。细长导引器还包括与通道通过开口或间隙流体连通的内腔。电极组件相对于开口在预定位置处装载在通道内。然后，诸如探针之类的加强构件的远端可以在内腔内并通过选定的一个开口进入以接合电极组件。探针的远端与电极组件一起沿通道内的远端方向推动，直到电极组件在预定的植入部位离开通道。然后将探针从电极组件脱耦合，并且远端再次缩回到内腔中。加强构件的远端可以被重新引导到不同的开口中以接合第二电极组件。在导引器在第二植入位置重新定位之后，第二电极组件可以以与上述相似的方式展开。可以重复该过程以展开电极阵列。根据本发明的一个方面，探针的远端倾斜以从导引器的内腔延伸到通道中。

7. 发明授权

US06379346B1 Introducer system 有权
标题翻译：介绍系统
公开(公告)号：US06379346B1
公开(公告)日：2002-04-30
申请号：US09552250
申请日：2000-04-18
申请人： Michael E. McIvor , Kenneth C. Gardeski , Pedro A. Meregotte , Matthew D. Bonner , Timothy G. Laske , Linda L. Lach
发明人： Michael E. McIvor , Kenneth C. Gardeski , Pedro A. Meregotte , Matthew D. Bonner , Timothy G. Laske , Linda L. Lach
IPC分类号： A61M2500
CPC分类号： A61M25/0668 , A61M25/01 , A61M2025/0675
摘要： An introducer is structured with an elongated tube having first and second lumens. A molded handle is coupled to the proximal end of the tube with an opening aligned with the first lumen. Further, a wall adjacent the opening of the handle defines a slot and is located diametrically opposite the second lumen. A tubular reinforcement member is located within the second lumen and the handle is provided with a second opening, thereby having a communication with the second lumen. In another embodiment a lead/catheter introducer includes an implantable lead or catheter having an elongated first lumen through which the lead or catheter passes and a second lumen extends parallel to the first lumen along at least a distal portion thereof. A tubular reinforcement member is disposed within the second lumen. The tubular reinforcement member further includes an internal lumen and a curvable stylet disposed in the lumen.
摘要翻译：导引器构造有具有第一和第二腔的细长管。模制手柄与管的近端连接，开口与第一内腔对准。此外，与手柄的开口相邻的壁限定了狭槽，并且位于与第二内腔完全相对的位置。管状加强构件位于第二内腔内，手柄设置有第二开口，从而与第二腔相连通。在另一个实施例中，引导/导管导引器包括具有细长的第一内腔的可植入引线或导管，所述引导件或导管通过所述细长的第一内腔，并且沿其至少其远端部分平行于所述第一内腔延伸的第二腔。管状加强构件设置在第二内腔内。管状加强构件还包括内腔和设置在内腔中的可调节探针。

8. 发明授权

US6146338A Apparatus for deflecting a catheter or lead 有权
公开(公告)号：US6146338A
公开(公告)日：2000-11-14
申请号：US298605
申请日：1999-04-23
申请人： Kenneth C. Gardeski , Corinne A. G. Poor , David Lipson
发明人： Kenneth C. Gardeski , Corinne A. G. Poor , David Lipson
IPC分类号： A61B1/005 , A61M25/00 , A61M25/01 , A61M25/16 , A61B5/00
CPC分类号： A61M25/0138 , A61M25/0144 , A61M25/0147 , A61B1/0051 , A61M25/0009
摘要： A deflectable stylet or guidewire formed of an elongated tube having a coil mounted to its distal end and a movable tension or push wire mounted within the coil and the tube, mechanically coupled to the distal end of the coil. A backbone is located within the coil, mechanically coupled to the proximal and distal ends of the coil and extending along one side of the coil. The backbone may be provided with projections extending laterally between adjacent turns of the coil and may have a generally arcuate cross section having a width greater than its arc height. In some embodiments the backbone may be formed from a tube having a slot extending longitudinally along one side thereof. In some embodiments the backbone may be attached to the coil at points between the proximal and distal ends of the coil.

9. 发明授权

US08509916B2 Bilumen guide catheters for accessing cardiac sites 有权
标题翻译：用于进入心脏部位的腹导管导管
公开(公告)号：US08509916B2
公开(公告)日：2013-08-13
申请号：US10319245
申请日：2002-12-16
申请人： Charles L. Byrd , Kenneth C. Gardeski , Michael R. Leners , Linda L. Lach , Ralph J. Thomas , Jesse T. Torbert , James F. Kelley
发明人： Charles L. Byrd , Kenneth C. Gardeski , Michael R. Leners , Linda L. Lach , Ralph J. Thomas , Jesse T. Torbert , James F. Kelley
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N2001/0578
摘要： Bilumen catheters and methods of using same for facilitating implantation of cardiac leads for applying electrical stimulation to and/or sensing electrical activity of the heart through one or more electrode positioned at an implantation site within a heart chamber or cardiac vessel adjacent a heart chamber, and more particularly to a method and apparatus for introducing such a cardiac lead having low torqueability and pushability through a tortuous pathway to enable attachment of the cardiac lead at the implantation site employing a bilumen guide catheter are disclosed. The bilumen catheter body includes a relatively large diameter delivery lumen to introduce a small diameter cardiac lead and a small diameter guide lumen to receive a stylet or guidewire to locate the guide catheter body distal end at the implantation site. The small diameter lumen within a small diameter guide tube extends distally from the delivery exit port of the delivery lumen.
摘要翻译：白细胞导管及其使用方法，用于促进心脏引线的植入，用于通过位于心室或邻近心室的心脏腔内的植入部位的一个或多个电极施加电刺激和/或感测心脏的电活动，以及更具体地涉及一种用于通过曲折路径引入具有低可逆性和推动性的这种心脏引线以使得能够使用柏油导引导管在植入部位处附着心脏引线的方法和装置。胆囊导管主体包括相对大直径的输送腔，以引入小直径心脏引线和小直径引导腔，以接收探针或导丝，以将引导导管主体远端定位在植入部位。小直径导管内的小直径内腔从输送腔的输送出口向远端延伸。

10. 发明授权

US07957789B2 Therapy delivery system including a navigation element 有权
标题翻译：治疗传递系统包括导航元件
公开(公告)号：US07957789B2
公开(公告)日：2011-06-07
申请号：US11322393
申请日：2005-12-30
申请人： Mark D. Schneider , Michael R. Neidert , Kenneth C. Gardeski , Johnson E. Goode
发明人： Mark D. Schneider , Michael R. Neidert , Kenneth C. Gardeski , Johnson E. Goode
IPC分类号： A61B5/05
CPC分类号： A61B19/5244 , A61B5/0084 , A61B5/055 , A61B5/6852 , A61B10/04 , A61B17/1214 , A61B17/3478 , A61B18/1492 , A61B18/18 , A61B34/20 , A61B34/25 , A61B90/36 , A61B90/39 , A61B2018/00071 , A61B2018/00839 , A61B2034/2051 , A61B2090/3958
摘要： An electromagnetic receiver assembly is included in a navigation element for a therapy delivery system. If the system is modular, the navigation element may be an insertable module thereof and/or include a lumen to receive another insertable module.
摘要翻译：用于治疗传送系统的导航元件中包括电磁接收器组件。如果系统是模块化的，则导航元件可以是其可插入模块和/或包括用于接收另一可插入模块的内腔。

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