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    • 2. 发明授权
    • Ferrocene compounds and preparation
    • 二茂铁化合物及其制备方法
    • US3960911A
    • 1976-06-01
    • US522591
    • 1974-11-11
    • John Louis SuschitzkyDavid Rutherford
    • John Louis SuschitzkyDavid Rutherford
    • C07F15/02C07F17/02
    • C07F17/02
    • There are described compounds of formula I, ##SPC1##in which R is alkyl, chlorine, bromine, phenyl, or phenyl substituted by one or more halogen or alkyl groups,One of X and Y is group --CO--, --CHOH-- or --CH.sub.2 -- and the other is an exocyclic carbon-carbon bond linking the ferrocenyl or the R group respectively to the -A- group,A contains 5, 6 or 7 carbon atoms and is an ethylenically unsaturated (the double bond being connected to the carbon atom which is connected to X), unsubstituted (except by X and Y) cyclic hydrocarbon group; or is a saturated cyclic hydrocarbon group substituted by X and Y and, when X is a group --CO-, optionally substituted on the carbon atom to which Y is attached by an -OH group, andX and Y are attached to adjacent carbon atoms on the A group. There are also described processes for the production of compounds of formula I and haematinic compositions containing them.
    • 描述式I化合物,其中R是烷基,氯,溴,苯基或被一个或多个卤素或烷基取代的苯基,其中一个X和Y是基团-CO-,-CHOH-或-CH 2 - 另一个是分别将二茂铁基或R基团连接到-A-基团的环状碳 - 碳键,A包含5,6或7个碳原子,并且是烯属不饱和的(双键连接到碳原子上 与X)连接,未取代(X和Y除外)环状烃基; 或者是被X和Y取代的饱和环状烃基,当X是-CO-时,任选地在与Y连接的碳原子上被取代,并且X和Y连接到相邻的碳原子上 在A组。 还描述了制备式I化合物和含有它们的血红素组合物的方法。