专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20110177784A1 METHOD AND SYSTEM FOR THE CONFIGURATION OF A MOBILE STATION BASEBAND CIRCUIT FOR AN ACOUSTIC ACCESSORY 有权
标题翻译：用于配置移动座椅基带电路的方法和系统
公开(公告)号：US20110177784A1
公开(公告)日：2011-07-21
申请号：US13050564
申请日：2011-03-17
申请人： Barry Steven Hazell , Kevin John Rush
发明人： Barry Steven Hazell , Kevin John Rush
IPC分类号： H04B7/00
CPC分类号： H04W4/008 , H04M1/6025 , H04M1/6041 , H04M1/72525 , H04M1/7253 , H04W4/80 , H04W88/02
摘要： A method and system for the configuration of a mobile station baseband circuit for an acoustic accessory having an identifier, the method comprising the steps of: determining whether the mobile device recognizes the identifier of the acoustic device; and configuring the baseband circuit with a DSP filter response and CODEC acoustic gain parameters for the acoustic device if the mobile device recognizes the identifier of the acoustic device. The system comprising: an identifier for each of the plurality of acoustic devices; a local memory in the mobile station storing a frequency (filter) response and gain parameters for at least one of the plurality of acoustic devices and for mapping them to the identifier; and a digital signal processor to re-shape an acoustic frequency response and adjust an audio gain of a baseband circuit for the mobile station based on the stored frequency response and gain parameters.
摘要翻译：一种用于配置具有标识符的声学附件的移动台基带电路的方法和系统，所述方法包括以下步骤：确定移动设备是否识别声学设备的标识符; 以及如果所述移动设备识别所述声学设备的标识符，则使用所述声学设备的DSP滤波器响应和CODEC声增益参数来配置所述基带电路。该系统包括：用于多个声学装置中的每一个的标识符; 移动站中的本地存储器存储用于多个声学装置中的至少一个的频率（滤波器）响应和增益参数，并将它们映射到标识符; 以及数字信号处理器，用于基于所存储的频率响应和增益参数来重新形成声频响应并调整用于移动台的基带电路的音频增益。

2. 发明授权

US07973134B2 Reagents for the detection of protein phosphorylation in anaplastic large cell lymphoma signaling pathways 有权
标题翻译：用于检测间变性大细胞淋巴瘤信号通路中蛋白质磷酸化的试剂
公开(公告)号：US07973134B2
公开(公告)日：2011-07-05
申请号：US11503096
申请日：2006-08-11
申请人： Albrecht Moritz , Kimberly Lee , John Rush , Roberto Polakiewicz
发明人： Albrecht Moritz , Kimberly Lee , John Rush , Roberto Polakiewicz
IPC分类号： C07K16/00 , C07K16/18
CPC分类号： G01N33/6842 , C07K16/44
摘要： The invention discloses 211 novel phosphorylation sites identified in signal transduction proteins and pathways underlying Anaplastic Large Cell Lymphoma (ALCL) involving the ALK-NPM translocation/fusion, and provides phosphorylation-site specific antibodies and heavy-isotope labeled peptides (AQUA peptides) for the selective detection and quantification of these phosphorylated sites/proteins, as well as methods of using the reagents for such purpose. Among the phosphorylation sites identified are sites occurring in the following protein types: Protein Kinases (including Receptor Tyrosine Kinases), Adaptor/Scaffold Proteins, Cellular Metabolism or Miscellaneous Enzymes, Oxidoreductases, Transcription Factors, Cytoskeletal Proteins, Translation Initiation Complexes, RNA Binding Proteins, Proteases, Acetyltransferases, G protein regulators/GTPases, Helicases, Apoptosis/Cell Cycle Regulation proteins, and Hydrolases.
摘要翻译：本发明公开了在信号转导蛋白中鉴定的211个新的磷酸化位点和涉及ALK-NPM易位/融合的间变性大细胞淋巴瘤（ALCL）的途径，并且为磷酸化位点特异性抗体和重同位素标记的肽（AQUA肽）提供了这些磷酸化位点/蛋白质的选择性检测和定量，以及使用试剂用于此目的的方法。鉴定的磷酸化位点是以下蛋白质类型发生的位点：蛋白激酶（包括受体酪氨酸激酶），适配器/支架蛋白，细胞代谢或其他酶，氧化还原酶，转录因子，细胞骨架蛋白，翻译起始复合物，RNA结合蛋白，蛋白酶，乙酰转移酶，G蛋白调节剂/ GTP酶，Helicases，细胞凋亡/细胞周期调节蛋白和水解酶。

3. 发明授权

US07300753B2 Immunoaffinity isolation of modified peptides from complex mixtures 有权
标题翻译：来自复杂混合物的修饰肽的免疫亲和分离
公开(公告)号：US07300753B2
公开(公告)日：2007-11-27
申请号：US10777893
申请日：2004-02-12
申请人： John Rush , Hui Zhang , Xiangming Zha , Michael J. Comb , Yi Tan
发明人： John Rush , Hui Zhang , Xiangming Zha , Michael J. Comb , Yi Tan
IPC分类号： C12Q1/00 , C12Q1/37 , C12P21/06 , G01N33/543
CPC分类号： G01N33/6872 , C07K14/47 , C07K16/44 , C12Q1/25 , C12Q1/485 , G01N33/6842
摘要： The invention provides methods for isolating a modified peptide from a complex mixture of peptides, the method comprising the steps of: (a) obtaining a proteinaceous preparation from an organism, wherein the preparation comprises modified peptides from two or more different proteins; (b) contacting the preparation with at least one immobilized modification-specific antibody; and (c) isolating at least one modified peptide specifically bound by the immobilized modification-specific antibody in step (b). The method may further comprise the step of (d) characterizing the modified peptide isolated in step (c) by mass spectrometry (MS), tandem mass spectrometry (MS—MS), and/or MS3 analysis, or the step of (e) utilizing a search program to substantially match the spectra obtained for the modified peptide during the characterization of step (d) with the spectra for a known peptide sequence, thereby identifying the parent protein(s) of the modified peptide. Also provided are an immunoaffinity isolation device comprising a modification-specific antibody, and antibodies against novel UFD1 and PTN6 phosphorylation sites.
摘要翻译：本发明提供了从复杂的肽混合物中分离修饰的肽的方法，所述方法包括以下步骤：（a）从生物体获得蛋白质制剂，其中所述制剂包含来自两种或更多种不同蛋白质的修饰肽; （b）使制剂与至少一种固定的修饰特异性抗体接触; 和（c）在步骤（b）中分离至少一种由固定的修饰特异性抗体特异性结合的修饰的肽。该方法还可以包括以下步骤：（d）通过质谱法（MS），串联质谱（MS-MS）和/或MS 3分析表征步骤（c）中分离的修饰肽或（e）利用搜索程序将在步骤（d）表征期间获得的修饰肽的光谱与已知肽序列的光谱基本上匹配，从而鉴定修饰的肽的亲本蛋白质肽。还提供了包含修饰特异性抗体和针对新型UFD1和PTN6磷酸化位点的抗体的免疫亲和分离装置。

4. 发明授权

US07198896B2 Immunoaffinity isolation of modified peptides from complex mixtures 有权
公开(公告)号：US07198896B2
公开(公告)日：2007-04-03
申请号：US10175486
申请日：2002-06-19
申请人： John Rush , Hui Zhang , Xiangming Zha , Michael J. Comb , Yi Tan
发明人： John Rush , Hui Zhang , Xiangming Zha , Michael J. Comb , Yi Tan
IPC分类号： C12Q1/00 , C12Q1/37 , C12P21/06 , G01N33/543
CPC分类号： C07K16/44
摘要： The invention provides methods for isolating a modified peptide from a complex mixture of peptides, the method comprising the steps of: (a) obtaining a proteinaceous preparation from an organism, wherein the preparation comprises modified peptides from two or more different proteins; (b) contacting the preparation with at least one immobilized modification-specific antibody; and (c) isolating at least one modified peptide specifically bound by the immobilized modification-specific antibody in step (b). The method may further comprise the step of (d) characterizing the modified peptide isolated in step (c) by mass spectrometry (MS), tandem mass spectrometry (MS—MS), and/or MS3 analysis, or the step of (e) utilizing a search program to substantially match the spectra obtained for the modified peptide during the characterization of step (d) with the spectra for a known peptide sequence, thereby identifying the parent protein(s) of the modified peptide. Also provided are an immunoaffinity isolation device comprising a modification-specific antibody, and antibodies against novel UFD1 and PTN6 phosphorylation sites.

5. 发明申请

US20060046651A1 Method and system for the configuration of a mobile station baseband circuit for an acoustic accessory 有权
公开(公告)号：US20060046651A1
公开(公告)日：2006-03-02
申请号：US10929491
申请日：2004-08-31
申请人： Barry Steven Hazell , Kevin John Rush
发明人： Barry Steven Hazell , Kevin John Rush
IPC分类号： H04M1/00 , H04B1/38
CPC分类号： H04W4/008 , H04M1/6025 , H04M1/6041 , H04M1/72525 , H04M1/7253 , H04W4/80 , H04W88/02
摘要： A method and system for the configuration of a mobile station baseband circuit for an acoustic accessory having an identifier, the method comprising the steps of: determining whether the mobile device recognizes the identifier of the acoustic device; and configuring the baseband circuit with a DSP filter response and CODEC acoustic gain parameters for the acoustic device if the mobile device recognizes the identifier of the acoustic device. The system comprising: an identifier for each of the plurality of acoustic devices; a local memory in the mobile station storing a frequency (filter) response and gain parameters for at least one of the plurality of acoustic devices and for mapping them to the identifier; and a digital signal processor to re-shape an acoustic frequency response and adjust an audio gain of a baseband circuit for the mobile station based on the stored frequency response and gain parameters.

6. 发明授权

US06698992B2 Elastically expandable positioning device 失效
标题翻译：弹性可扩展定位装置
公开(公告)号：US06698992B2
公开(公告)日：2004-03-02
申请号：US10234513
申请日：2002-09-05
申请人： Kung Chris Wu , Torben J. Ulander , Chawshiang Wu , John Rush
发明人： Kung Chris Wu , Torben J. Ulander , Chawshiang Wu , John Rush
IPC分类号： B65F302
CPC分类号： H01L21/67775 , H01L21/68 , Y10S414/139
摘要： An elastically expandable positioning device for positioning a cover of a unified pod is disclosed, which has a central fastener having one end protruded on the interface plate and an axial input hole opened at another end, and at least one radial distributing hole equally opened at its circular surface; a ring-shaped inflatable body made from an expandable elastic material; a supporting ring encircled around the central bolt and positioned above the distributing hole, for supporting the inflatable body, the supporting ring having at least one radial inflating hole equally positioned corresponding to the radial distributing hole of the central bolt; and an input fluid source connected to the axial input hole of the central bolt, for providing an input fluid.
摘要翻译：公开了一种用于定位统一舱盖的可弹性扩张的定位装置，其具有中心紧固件，该中心紧固件具有在接口板上突出的一端和在另一端开口的轴向输入孔，以及在其上同等开口的至少一个径向分配孔圆形表面由可膨胀弹性材料制成的环形可充气体; 围绕中心螺栓环绕并位于分配孔上方的支撑环，用于支撑可充气体，支撑环具有至少一个相应于中心螺栓的径向分布孔等同定位的径向充气孔; 以及连接到中心螺栓的轴向输入孔的输入流体源，用于提供输入流体。

7. 发明授权

US1432391A Shoe rack 失效
公开(公告)号：US1432391A
公开(公告)日：1922-10-17
申请号：US45991821
申请日：1921-04-09
申请人： JOHN RUSH GREEN
发明人： RUSH GREEN JOHN , WILLIAMS FRANHLIN S , AIME LAVALLEE JOSEPH
IPC分类号： A43D117/00
CPC分类号： A43D117/00

8. 发明授权

US1127180A Slotting-machine. 失效
公开(公告)号：US1127180A
公开(公告)日：1915-02-02
申请号：US1908424474
申请日：1908-04-01
申请人： JOHN RUSH GREEN
发明人： BRYAR GEORGE
CPC分类号： B23Q1/28 , Y10T409/30 , Y10T409/30448 , Y10T409/30756

9. 发明授权

US08618260B2 Tyrosine, serine and threonine phosphorylation sites 有权
公开(公告)号：US08618260B2
公开(公告)日：2013-12-31
申请号：US12310852
申请日：2007-09-08
申请人： Peter Hornbeck , Albrecht Moritz , John Rush , Steven Gygi
发明人： Peter Hornbeck , Albrecht Moritz , John Rush , Steven Gygi
IPC分类号： C07K16/00
CPC分类号： G01N33/6842 , C07K16/44 , G01N2440/14
摘要： The invention discloses 155 novel phosphorylation sites identified in carcinoma and leukemia, peptides (including AQUA peptides) comprising a phosphorylation site of the invention, antibodies specifically bind to a novel phosphorylation site of the invention, and diagnostic and therapeutic uses of the above.

10. 发明申请

US20130004963A1 Tyrosine, serine and threonine phosphorylation sites 有权
标题翻译：酪氨酸，丝氨酸和苏氨酸磷酸化位点
公开(公告)号：US20130004963A1
公开(公告)日：2013-01-03
申请号：US12310852
申请日：2007-09-08
申请人： Peter Hornbeck , Judit Villen , Albrecht Moritz , John Rush , Steven Gygi , Sean Beausoleil , Scott Gerber
发明人： Peter Hornbeck , Judit Villen , Albrecht Moritz , John Rush , Steven Gygi , Sean Beausoleil , Scott Gerber
IPC分类号： G01N33/566 , C07K16/18 , G01N33/573
CPC分类号： G01N33/6842 , C07K16/44 , G01N2440/14
摘要： The invention discloses 155 novel phosphorylation sites identified in carcinoma and leukemia, peptides (including AQUA peptides) comprising a phosphorylation site of the invention, antibodies specifically bind to a novel phosphorylation site of the invention, and diagnostic and therapeutic uses of the above.
摘要翻译：本发明公开了在癌和白血病中鉴定的155个新的磷酸化位点，包含本发明的磷酸化位点的肽（包括AQUA肽），特异性结合本发明的新的磷酸化位点的抗体，以及上述的诊断和治疗用途。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式