专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09856466B2 Compositions and methods comprising serine protease variants 有权
公开(公告)号：US09856466B2
公开(公告)日：2018-01-02
申请号：US14115801
申请日：2012-05-04
申请人： Neelam S. Amin , Katherine Augustyn , Joshua R. Basler , Luis G. Cascao-Pereira , Katherine D. Collier , Edward M. Concar , David A. Estell , James T. Kellis, Jr. , Euan John Magennis , Alexander Pisarchik , Ayrookaran J. Poulose , Philip Frank Souter , Glenn Steven Ward , Jian Yao
发明人： Neelam S. Amin , Katherine Augustyn , Joshua R. Basler , Luis G. Cascao-Pereira , Katherine D. Collier , Edward M. Concar , David A. Estell , James T. Kellis, Jr. , Euan John Magennis , Alexander Pisarchik , Ayrookaran J. Poulose , Philip Frank Souter , Glenn Steven Ward , Jian Yao
IPC分类号： C12N9/54 , C11D3/386
CPC分类号： C12N9/54 , C11D3/386
摘要： The present invention provides serine protease variants, more specifically subtilisin variants produced there from. Specifically, the present invention provides serine protease variants, more specifically subtilisin variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants, more specifically subtilisin variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants, more specifically subtilisin variants.

2. 发明申请

US20130260438A1 COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS (AS AMENDED) 审中-公开
标题翻译：包含丝氨酸蛋白酶变体（如修订）的组合物和方法
公开(公告)号：US20130260438A1
公开(公告)日：2013-10-03
申请号：US13696512
申请日：2011-05-05
申请人： Viktor Yuryevich Alekseyev , Neelam A Amin , Katherine Auguslyn , Luis Gustavo Cascao-Pereira , Katherine D. Collier , David A. Estell , James T. Kellis, JR. , Ayrookaran J. Poulose , Philip Frank Souter , Glenn Steven Ward , Jian Yao
发明人： Viktor Yuryevich Alekseyev , Neelam A Amin , Katherine Auguslyn , Luis Gustavo Cascao-Pereira , Katherine D. Collier , David A. Estell , James T. Kellis, JR. , Ayrookaran J. Poulose , Philip Frank Souter , Glenn Steven Ward , Jian Yao
IPC分类号： C12N9/54
CPC分类号： C12N9/54 , C11D3/386 , C11D3/38681
摘要： The present invention provides serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
摘要翻译：本发明提供了丝氨酸蛋白酶变体。具体地，本发明提供了与参考丝氨酸蛋白酶相比具有一个或多个取代的丝氨酸蛋白酶变体。此外，本发明提供包含这些丝氨酸蛋白酶变体的组合物。在一些实施方案中，本发明提供了包含这些丝氨酸蛋白酶变体中的至少一种的清洁组合物。

3. 发明申请

US20110312064A1 METHODS OF REMOVING OILY STAINS FROM FABRICS 审中-公开
标题翻译：从织物中去除油性污渍的方法
公开(公告)号：US20110312064A1
公开(公告)日：2011-12-22
申请号：US13132071
申请日：2009-11-30
申请人： Christian D. Adams , Katherine D. Collier , Thjs Kaper , Brian F. Schmidt
发明人： Christian D. Adams , Katherine D. Collier , Thjs Kaper , Brian F. Schmidt
IPC分类号： C12S11/00 , C11D3/60
CPC分类号： C11D3/38627 , C11D3/222 , C11D3/38636 , C11D11/0017
摘要： Described are compositions and methods for removing oily stains from fabrics by treating the fabrics with cyclodextrins. Cyclodextrins can be added to the fabrics or generated in situ by converting a substrate of starch or dextrin with cyclomaltodextrin glucanotransferase.
摘要翻译：描述了通过用环糊精处理织物来从织物中除去油性污渍的组合物和方法。可以将环糊精加入到织物中或通过用环糊精葡聚糖转移酶转化淀粉或糊精的底物而在原位产生。

4. 发明申请

US20110256608A1 Modified Variant Bowman Birk Protease Inhibitors 有权
标题翻译：改良变体Bowman Birk蛋白酶抑制剂
公开(公告)号：US20110256608A1
公开(公告)日：2011-10-20
申请号：US13082979
申请日：2011-04-08
申请人： Neelam S. Amin , Katherine D. Collier , Melodie Estabrook , David A. Estell , Bryan P. Fox , Scott D. Power , Brian F. Schmidt , Gudrun Vogtentanz
发明人： Neelam S. Amin , Katherine D. Collier , Melodie Estabrook , David A. Estell , Bryan P. Fox , Scott D. Power , Brian F. Schmidt , Gudrun Vogtentanz
IPC分类号： C12N9/42 , C12N1/21 , C12N9/00 , C12N15/63
CPC分类号： C07K14/811 , A61K8/64 , A61Q7/02
摘要： The present invention relates to modified variant Bowman Birk Protease Inhibitor proteins (BBPIs) that comprise peptides that bind target proteins, and that are further modified to have greater protease inhibitory activity and/or be produced at greater yields than the unmodified BBPIs. The invention encompasses polynucleotide constructs and expression vectors containing polynucleotide sequences that encode the modified variant BBPIs, the transformed host cells that express and produce the modified variant BBPIs, the modified variant BBPI proteins, the compositions comprising the modified variant BBPIs, and the methods for making and using the modified variant BBPIs in personal care.
摘要翻译：本发明涉及包含结合靶蛋白的肽的修饰变体Bowman Birk蛋白酶抑制剂蛋白（BBPI），并且被进一步修饰以具有比未修饰的BBPI更大的蛋白酶抑制活性和/或以更高的产量产生。本发明包括多核苷酸构建体和含有编码修饰变体BBPI的多核苷酸序列的表达载体，表达和产生修饰变体BBPI的转化宿主细胞，修饰变体BBPI蛋白，包含修饰变体BBPI的组合物和制备方法并在个人护理中使用修改后的变体BBPI。

5. 发明授权

US07947475B2 Modified variant Bowman Birk protease inhibitors 有权
标题翻译：改良型Bowman Birk蛋白酶抑制剂
公开(公告)号：US07947475B2
公开(公告)日：2011-05-24
申请号：US12779793
申请日：2010-05-13
申请人： Neelam S. Amin , Katherine D. Collier , Melodie Estabrook , David A. Estell , Bryan P. Fox , Scott D. Power , Brian F. Schmidt , Gudrun Vogtentanz
发明人： Neelam S. Amin , Katherine D. Collier , Melodie Estabrook , David A. Estell , Bryan P. Fox , Scott D. Power , Brian F. Schmidt , Gudrun Vogtentanz
IPC分类号： C12P21/00
CPC分类号： C07K14/811 , A61K8/64 , A61Q7/02
摘要： The present invention relates to modified variant Bowman Birk Protease Inhibitor proteins (BBPIs) that comprise peptides that bind target proteins, and that are further modified to have greater protease inhibitory activity and/or be produced at greater yields than the unmodified BBPIs. The invention encompasses polynucleotide constructs and expression vectors containing polynucleotide sequences that encode the modified variant BBPIs, the transformed host cells that express and produce the modified variant BBPIs, the modified variant BBPI proteins, the compositions comprising the modified variant BBPIs, and the methods for making and using the modified variant BBPIs in personal care.
摘要翻译：本发明涉及包含结合靶蛋白的肽的修饰变体Bowman Birk蛋白酶抑制剂蛋白（BBPI），并且被进一步修饰以具有比未修饰的BBPI更大的蛋白酶抑制活性和/或以更高的产量产生。本发明包括多核苷酸构建体和含有编码修饰变体BBPI的多核苷酸序列的表达载体，表达和产生修饰变体BBPI的转化宿主细胞，修饰变体BBPI蛋白，包含修饰变体BBPI的组合物和制备方法并在个人护理中使用修改后的变体BBPI。

6. 发明授权

US07772181B2 Personal care compositions comprising modified variant Bowman Birk Protease Inhibitors 有权
标题翻译：包含修饰变体Bowman Birk蛋白酶抑制剂的个人护理组合物
公开(公告)号：US07772181B2
公开(公告)日：2010-08-10
申请号：US12252032
申请日：2008-10-15
申请人： Neelam S. Amin , Katherine D. Collier , Melodie Estabrook , David A. Estell , Bryan P. Fox , Scott D. Power , Brian F. Schmidt , Gudrun Vogtentanz
发明人： Neelam S. Amin , Katherine D. Collier , Melodie Estabrook , David A. Estell , Bryan P. Fox , Scott D. Power , Brian F. Schmidt , Gudrun Vogtentanz
IPC分类号： A61K38/00 , A61K8/00
CPC分类号： A61K8/64 , A61K38/55 , A61Q1/02 , A61Q1/04 , A61Q1/06 , A61Q1/10 , A61Q3/00 , A61Q3/02 , A61Q5/006 , A61Q5/02 , A61Q5/06 , A61Q5/12 , A61Q17/04 , A61Q19/00 , A61Q19/002 , A61Q19/04 , A61Q19/10
摘要： The present invention relates to compositions that comprise modified variant Bowman Birk Protease Inhibitor proteins (BBPIs). The modified variant BBPIs comprise peptides that bind target proteins, and that are further modified to have greater protease inhibitory activity and/or be produced at greater yields than the unmodified BBPIs. The invention encompasses the compositions comprising the modified variant BBPIs, and the methods for making and using the compositions in personal care.
摘要翻译：本发明涉及包含修饰的变体Bowman Birk蛋白酶抑制蛋白（BBPI）的组合物。修饰的变体BBPI包含结合靶蛋白的肽，并且被进一步修饰以具有比未修饰的BBPI更大的蛋白酶抑制活性和/或以更高的产量产生。本发明包括包含修饰变体BBPI的组合物，以及在个人护理中制备和使用组合物的方法。

7. 发明授权

US06620605B2 Method and compositions for treating cellulose containing fabrics using truncated cellulase enzyme compositions 失效
公开(公告)号：US06620605B2
公开(公告)日：2003-09-16
申请号：US09916494
申请日：2001-07-27
申请人： Timothy Fowler , Kathleen A. Clarkson , Michael Ward , Katherine D. Collier , Edmund Larenas
发明人： Timothy Fowler , Kathleen A. Clarkson , Michael Ward , Katherine D. Collier , Edmund Larenas
IPC分类号： C12N942
CPC分类号： D06P5/158 , A23K20/189 , C11D3/38645 , C12N9/2437 , C12N15/80 , C12Y302/01004 , C12Y302/01021 , C12Y302/01091 , D06M16/003 , D06P5/02 , D06P5/137 , Y10T442/20
摘要： Improved methods of treating cellulose containing fabrics with cellulase comprising contacting the cellulose fabrics with truncated cellulase enzyme. Treatment of cellulose containing fabrics with cellulase core domains of the invention are disclosed as offering specific advantages of reduced redeposition of dye and increased abrasion.

8. 发明申请

US20100093028A1 MODIFIED VARIANT BOWMAN BIRK PROTEASE INHIBITORS 有权
标题翻译：改良变体BOWMAN BIRK PROTEASE抑制剂
公开(公告)号：US20100093028A1
公开(公告)日：2010-04-15
申请号：US12252062
申请日：2008-10-15
申请人： Neelam S. Amin , Katherine D. Collier , Melodie Estabrook , David A. Estell , Bryan P. Fox , Scott D. Power , Brian F. Schmidt , Gudrun Vogtentanz
发明人： Neelam S. Amin , Katherine D. Collier , Melodie Estabrook , David A. Estell , Bryan P. Fox , Scott D. Power , Brian F. Schmidt , Gudrun Vogtentanz
IPC分类号： C12P21/00 , C07K14/00 , C12N15/74 , C12N5/10
CPC分类号： C07K14/811 , A61K8/64 , A61Q7/02
摘要： The present invention relates to modified variant Bowman Birk Protease Inhibitor proteins (BBPIs) that comprise peptides that bind target proteins, and that are further modified to have greater protease inhibitory activity and/or be produced at greater yields than the unmodified BBPIs. The invention encompasses polynucleotide constructs and expression vectors containing polynucleotide sequences that encode the modified variant BBPIs, the transformed host cells that express and produce the modified variant BBPIs, the modified variant BBPI proteins, the compositions comprising the modified variant BBPIs, and the methods for making and using the modified variant BBPIs in personal care.
摘要翻译：本发明涉及包含结合靶蛋白的肽的修饰变体Bowman Birk蛋白酶抑制剂蛋白（BBPI），并且被进一步修饰以具有比未修饰的BBPI更大的蛋白酶抑制活性和/或以更高的产量产生。本发明包括多核苷酸构建体和含有编码修饰变体BBPI的多核苷酸序列的表达载体，表达和产生修饰变体BBPI的转化宿主细胞，修饰变体BBPI蛋白，包含修饰变体BBPI的组合物和制备方法并在个人护理中使用修改后的变体BBPI。

9. 发明授权

US07122334B2 Method of assaying wash performance of enzymes on a microtiter plate 有权
标题翻译：测定微量滴定板上酶的洗涤性能的方法
公开(公告)号：US07122334B2
公开(公告)日：2006-10-17
申请号：US10899751
申请日：2004-07-26
申请人： Volker Schellenberger , Donald P. Naki , Katherine D. Collier , James T. Kellis, Jr. , Joanne Nadherny
发明人： Volker Schellenberger , Donald P. Naki , Katherine D. Collier , James T. Kellis, Jr. , Joanne Nadherny
IPC分类号： C12Q1/34
CPC分类号： C12Q1/00
摘要： A microtiter method for assaying the wash performance of new enzymes and/or new detergent formulations is described.
摘要翻译：描述了用于测定新酶和/或新洗涤剂制剂的洗涤性能的微量滴定法。

10. 发明授权

US07005128B1 Enzyme feed additive and animal feed including it 失效
标题翻译：酶饲料添加剂和动物饲料包括它
公开(公告)号：US07005128B1
公开(公告)日：2006-02-28
申请号：US10379978
申请日：2003-03-04
申请人： Michael R. Bedford , Andrew J. Morgan , Timothy Fowler , Kathleen A. Clarkson , Michael Ward , Katherine D. Collier , Edmund A Larenas
发明人： Michael R. Bedford , Andrew J. Morgan , Timothy Fowler , Kathleen A. Clarkson , Michael Ward , Katherine D. Collier , Edmund A Larenas
IPC分类号： A61K38/47 , A61K38/43 , A61K38/54 , A23K1/00
CPC分类号： C12Y302/01004 , A23K20/189 , A23K50/75 , C12N9/2437 , C12Y302/01091
摘要： The use is provided of a composition as a feed additive which comprises one or more endoglucanases, and 0–20% by weight, based upon the content of cellulase proteins in the composition, of a cellobiohydrolase. The endoglycanases may be one or more of EGI, EGII, EGIII and any functionally active derivative of any thereof. Such endoglucanases may be obtained from a genetically modified strain of the fungus Trichoderma. Also provided is an enzyme-based feed additive which comprises EGI and/or EGII which lack the cellulose binding domain, and 0–20% by weight, based upon the content of cellulase proteins in the additive, of a cellobiohydrolase. A further enzyme-based feed additive is provided which comprises a cereal-based carrier, one or more endoglucanases, and 0–20% by weight, based upon the content of cellulase proteins in the additive, of a cellobiohydrolase. Such enzyme-based feed additives can be incorporated into a cereal-based feed which includes one or more of barley, wheat, triticale, rye and maize. The feed additive has the advantage of improving the feed conversion ratio and/or increasing the digestibility of a cereal-based feed in which it is included.
摘要翻译：提供的组合物作为饲料添加剂，其包含一种或多种内切葡聚糖酶，并且基于组合物中纤维素酶蛋白质的含量为0-20重量％的纤维二糖水解酶。所述凝集素可以是EGI，EGII，EGIII及其任何的任何功能活性衍生物中的一种或多种。这样的内切葡聚糖酶可以从真菌木霉的遗传修饰菌株获得。还提供了一种基于酶的饲料添加剂，其包含缺乏纤维素结合结构域的EGI和/或EGII，并且基于添加剂中纤维素酶蛋白质的含量为0-20重量％的纤维二糖水解酶。提供了另外一种基于酶的饲料添加剂，其包含基于谷物的载体，一种或多种内切葡聚糖酶，和基于添加剂中的纤维素酶蛋白质含量为0-20重量％的纤维二糖水解酶。这种基于酶的饲料添加剂可以掺入包括大麦，小麦，黑小麦，黑麦和玉米中的一种或多种的谷类饲料中。饲料添加剂具有提高饲料转化率和/或增加其中包含谷物饲料的消化率的优点。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式