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1. 发明授权

US09925124B2 Dental composition suitable for grinding with automatic grinding apparatus 有权
公开(公告)号：US09925124B2
公开(公告)日：2018-03-27
申请号：US13408050
申请日：2012-02-29
申请人： Yusei Kadobayashi , Masako Shigezawa , Keiji Takahashi
发明人： Yusei Kadobayashi , Masako Shigezawa , Keiji Takahashi
IPC分类号： A61K6/083 , A61K6/00 , A61C13/00
CPC分类号： A61K6/0008 , A61C13/0022 , A61K6/083 , C08L33/10
摘要： Provided is a dental composition comprising a first largest group of particles and resin matrix, wherein the first largest group consists of particles whose particle size ranges from 0.7 to 1.5 times the representative particle size of the first largest fraction in a population of particles included in the composition whose particle size ranges from 110 to 1000 μm; and wherein the ratio of the number of particles included in the first largest group to the number of particles whose particle size ranges from 0.5 to 2.0 times the representative particle size of the first largest fraction is equal to or more than 0.8.

2. 发明授权

US08648279B2 Process control apparatus and laser processing apparatus 有权
标题翻译：过程控制装置和激光加工装置
公开(公告)号：US08648279B2
公开(公告)日：2014-02-11
申请号：US12936120
申请日：2009-04-03
申请人： Keiji Takahashi , Tomonori Mukae , Shigeru Yokoi , Tatsuya Yamamoto
发明人： Keiji Takahashi , Tomonori Mukae , Shigeru Yokoi , Tatsuya Yamamoto
IPC分类号： B23K26/04
CPC分类号： B23K26/046 , G02B7/008 , G02B7/028
摘要： A process control apparatus controls a focus position of a laser beam, while a laser processing mechanism converges the laser beam into a predetermined focus position and performs a laser processing on a workpiece. The process control apparatus includes: a calculator that, based on the magnitude of an output of the laser beam that changes during the laser processing, calculates a change amount of a positional deviation of the focus position in an optical axis direction that changes during the laser processing at a laser beam radiation position; and a control unit that, based on the change amount of the positional deviation that has been calculated by the calculator, controls the focus position of the laser beam during the laser processing so as to resolve the positional deviation of the focus position.
摘要翻译：过程控制装置控制激光束的焦点位置，而激光加工机构将激光束会聚到预定的聚焦位置，并对工件进行激光加工。该处理控制装置包括：计算器，其基于在激光处理期间发生变化的激光束的输出的大小来计算在激光器内变化的光轴方向上的聚焦位置的位置偏差的变化量在激光束辐射位置处理; 以及控制单元，其基于由计算器计算出的位置偏差的变化量来控制激光处理期间的激光束的聚焦位置，以便解析聚焦位置的位置偏差。

3. 发明授权

US07932394B2 Aryloxy-substituted benzimidazole derivatives 有权
标题翻译：芳氧基取代的苯并咪唑衍生物
公开(公告)号：US07932394B2
公开(公告)日：2011-04-26
申请号：US11666555
申请日：2005-11-01
申请人： Noriaki Hashimoto , Keiji Takahashi , Chisato Nakama , Yoshio Ogino , Fumiko Sakai , Teruyuki Nishimura , Jun-ichi Eiki
发明人： Noriaki Hashimoto , Keiji Takahashi , Chisato Nakama , Yoshio Ogino , Fumiko Sakai , Teruyuki Nishimura , Jun-ichi Eiki
IPC分类号： C07D401/00 , A61K31/445
CPC分类号： A61K38/31 , A61K31/155 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/497 , A61K31/506 , A61K38/28 , A61K45/06 , C07D401/04 , C07D401/14 , C07D413/06 , C07D413/14 , A61K2300/00
摘要： A glucokinase activator is provided; and a treatment and/or a preventive for diabetes, or a treatment and/or a preventive for diabetes such as retinopathy, nephropathy, neurosis, ischemic cardiopathy, arteriosclerosis, and further a treatment and/or a preventive for obesity are provided.The invention relates to a compound of a formula (I): [wherein R1 and R2 represent a hydrogen, etc.; R3 represents a hydrogen atom, a halogen atom, etc.; R4 each independently represents a hydrogen atom, a lower alkyl group, etc.; Q represents a carbon atom, a nitrogen atom or a sulfur atom (the sulfur atom may be mono- or di-substituted with an oxo group); R5 and R6 each represent a hydrogen atom, a lower alkyl group, etc.; X1, X2, X3 and X4 each independently represent a carbon atom or a nitrogen atom; Z represents an oxygen atom, a sulfur atom or a nitrogen atom; Ar represents an aryl or heteroaryl group optionally mono to tri-substituted with a group selected from the substituent group β; ring A represents a 5- or 6-membered nitrogen-containing heteroaromatic group; m indicates an integer of from 1 to 6; n indicates an integer of from 0 to 3; p indicates an integer of from 0 to 2 (provided that at least two of X1 to X4 are carbon atoms); q indicates 0 or 1] or its pharmaceutically-acceptable salt, which has an effect of glucokinase activation and is useful as a treatment for diabetes.
摘要翻译：提供葡糖激酶活化剂; 提供糖尿病的治疗和/或预防，或治疗和/或预防糖尿病如视网膜病，肾病，神经症，缺血性心脏病，动脉硬化，以及进一步的治疗和/或预防肥胖症。本发明涉及式（I）化合物：其中R 1和R 2表示氢等; R3表示氢原子，卤原子等; R4各自独立地表示氢原子，低级烷基等; Q表示碳原子，氮原子或硫原子（硫原子可以被氧代基单取代或二取代）。 R5和R6各自表示氢原子，低级烷基等; X1，X2，X3和X4各自独立地表示碳原子或氮原子; Z表示氧原子，硫原子或氮原子; Ar表示任选被选自取代基组中的基团单取代至三取代的芳基或杂芳基; 环A表示5-或6-元含氮杂芳基; m表示1〜6的整数， n表示0〜3的整数， p表示0〜2的整数（X1〜X4中的至少2个为碳原子）。 q表示0或1]或其药学上可接受的盐，其具有葡糖激酶活化的作用，并且可用作糖尿病的治疗。

4. 发明申请

US20100302482A1 COLOR FILTER SUBSTRATE, LIQUID CRYSTAL DISPLAY PANEL, LIQUID CRYSTAL DISPLAY DEVICE, AND PRODUCTION METHOD OF COLOR FILTER SUBSTRATE 审中-公开
标题翻译：彩色滤光片，液晶显示面板，液晶显示装置及彩色滤光片基板的制作方法
公开(公告)号：US20100302482A1
公开(公告)日：2010-12-02
申请号：US12744983
申请日：2008-09-09
申请人： Keiji Takahashi , Shingo Johgan , Hisashi Nagata
发明人： Keiji Takahashi , Shingo Johgan , Hisashi Nagata
IPC分类号： G02F1/1335
CPC分类号： G02B5/201 , G02F1/133512 , G02F1/133516
摘要： The present invention provides a color filter substrate which achieves a sufficient light-shielding effect in a light-shielding region and can prevent a disorder of the alignment of liquid crystals in the vicinity of the light-shielding region. The present invention is a color filter substrate including: a light-shielding layer and a colored layer made of material such as a photosensitive material, on a substrate, wherein the colored layer is arranged from a light transmission region not having the light-shielding layer arranged therein to a light-shielding region having the light-shielding layer arranged therein, and has a smaller thickness in the light-shielding region than in the light transmission region.
摘要翻译：本发明提供一种滤色器基板，其在遮光区域中具有足够的遮光效果，并且能够防止在遮光区域附近的液晶的取向紊乱。本发明是一种滤色器基板，其包括：遮光层和由诸如感光材料的材料制成的着色层，在基板上，其中着色层从不具有遮光层的光透射区域布置布置在其中布置有遮光层的遮光区域，并且在光屏蔽区域中比在透光区域中具有更小的厚度。

5. 发明授权

US07799820B2 2-Heterocycle-substituted indole derivatives for treating diabetes and associated conditions 有权
标题翻译：用于治疗糖尿病和相关病症的2-杂环取代的吲哚衍生物
公开(公告)号：US07799820B2
公开(公告)日：2010-09-21
申请号：US11992555
申请日：2006-09-29
申请人： Keiji Takahashi , Yoshio Ogino , Teruyuki Nishimura
发明人： Keiji Takahashi , Yoshio Ogino , Teruyuki Nishimura
IPC分类号： A61K31/405
CPC分类号： C07D401/04 , C07D401/14 , C07D413/14 , C07D471/04
摘要： Disclosed is a compound represented by the formula (I) below, which has a glucokinase-activating effect and is thus useful for treatment of diabetes or obesity, or a pharmaceutically acceptable salt thereof. In the formula, R1 represents an aryl or the like; R11 represents an aryl or the like; R2 represents a formyl or the like, R3 represents a C1-6 alkyl or the like; R3 represents a hydrogen atom or the like; Z1 represents —O— or the like; Z2 represents —O— or the like; Y1-Y4 respectively represent a carbon atom or a nitrogen atom; ring A represents a heteroaryl group; X represents a carbon atom or the like; m represents an integer of 0-2; and q represents an integer of 0-2.
摘要翻译：公开了由下式（I）表示的化合物，其具有葡糖激酶活化作用，因此可用于治疗糖尿病或肥胖症或其药学上可接受的盐。在该式中，R 1表示芳基等; R11表示芳基等; R 2表示甲酰基等，R 3表示C 1-6烷基等; R3表示氢原子等; Z1表示-O-等; Z2表示-O-等; Y1-Y4分别表示碳原子或氮原子; 环A表示杂芳基; X表示碳原子等; m表示0-2的整数; q表示0-2的整数。

6. 发明申请

US20100222394A1 METHOD FOR PRODUCING PYRAZOL-3-YL-BENZAMIDE DERIVATIVE 审中-公开
标题翻译：生产吡唑-3-基-L-苯甲酰胺衍生物的方法
公开(公告)号：US20100222394A1
公开(公告)日：2010-09-02
申请号：US12679836
申请日：2008-09-25
申请人： Kenichi Asakawa , Naotaka Sawada , Takayuki Tsuritani , Toshiaki Mase , Keiji Takahashi , Takahiro Itoh , Feng Xu , Naoki Yoshikawa
发明人： Kenichi Asakawa , Naotaka Sawada , Takayuki Tsuritani , Toshiaki Mase , Keiji Takahashi , Takahiro Itoh , Feng Xu , Naoki Yoshikawa
IPC分类号： A61K31/4439 , C07D401/12 , C07D213/71 , A61P3/10 , A61P3/04
CPC分类号： C07D213/71 , C07D401/12 , C07D487/08
摘要： The present invention provides a more efficient industrial method for producing a pyrazol-3-yl-benzamide derivative expressed by a formula useful as medicine: wherein R2, R3 and R4 each independently represent a lower alkyl group.
摘要翻译：本发明提供了用于制备由用作药物的式表示的吡唑-3-基 - 苯甲酰胺衍生物的更有效的工业方法：其中R2，R3和R4各自独立地表示低级烷基。

7. 发明申请

US20090118304A1 2-HETEROARYL-SUBSTITUTED INDOLE DERIVATIVE 有权
标题翻译： 2-HETEROARYL取代的吲哚衍生物
公开(公告)号：US20090118304A1
公开(公告)日：2009-05-07
申请号：US11992555
申请日：2006-09-29
申请人： Keiji Takahashi , Yoshio Ogino , Teruyuki Nishimura
发明人： Keiji Takahashi , Yoshio Ogino , Teruyuki Nishimura
IPC分类号： A61K31/497 , C07D401/14 , A61K31/437 , A61P3/10 , C07D471/04
CPC分类号： C07D401/04 , C07D401/14 , C07D413/14 , C07D471/04
摘要： Disclosed is a compound represented by the formula (I) below, which has a glucokinase-activating effect and is thus useful for treatment of diabetes or obesity, or a pharmaceutically acceptable salt thereof. In the formula, R1 represents an aryl or the like; R11 represents an aryl or the like; R2 represents a formyl or the like, R3 represents a C1-6 alkyl or the like; R3 represents a hydrogen atom or the like; Z1 represents —O— or the like; Z2 represents —O— or the like; Y1-Y4 respectively represent a carbon atom or a nitrogen atom; ring A represents a heteroaryl group; X represents a carbon atom or the like; m represents an integer of 0-2; and q represents an integer of 0-2.
摘要翻译：公开了由下式（I）表示的化合物，其具有葡糖激酶活化作用，因此可用于治疗糖尿病或肥胖症或其药学上可接受的盐。在该式中，R 1表示芳基等; R11表示芳基等; R 2表示甲酰基等，R 3表示C 1-6烷基等; R3表示氢原子等; Z1表示-O-等; Z2表示-O-等; Y1-Y4分别表示碳原子或氮原子; 环A表示杂芳基; X表示碳原子等; m表示0-2的整数; q表示0-2的整数。

8. 发明授权

US07432287B2 Heteroarylcarbamoylbenzene derivative 有权
标题翻译：杂芳基氨基甲酰基苯衍生物
公开(公告)号：US07432287B2
公开(公告)日：2008-10-07
申请号：US10546962
申请日：2004-02-26
申请人： Tomoharu Iino , Noriaki Hashimoto , Hiroshi Nakashima , Keiji Takahashi , Teruyuki Nishimura , Jun-ichi Eiki
发明人： Tomoharu Iino , Noriaki Hashimoto , Hiroshi Nakashima , Keiji Takahashi , Teruyuki Nishimura , Jun-ichi Eiki
IPC分类号： A61K31/4439 , A61K31/4155 , C07D401/10 , C07D231/40
CPC分类号： C07D213/75 , C07D231/40 , C07D237/20 , C07D239/42 , C07D241/20 , C07D249/04 , C07D261/14 , C07D271/07 , C07D275/03 , C07D277/18 , C07D277/46 , C07D277/60 , C07D277/82 , C07D285/08 , C07D285/10 , C07D285/135 , C07D401/12 , C07D405/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D513/04
摘要： Compounds represented by formula (I): as well as their pharmaceutically acceptable salts are disclosed. The compounds are useful as glucokinase activating agents for the treatment of diabetes and related conditions. Compositions and methods of treatment are also included.
摘要翻译：公开了由式（I）表示的化合物及其药学上可接受的盐。该化合物可用作糖尿病治疗和相关病症的葡糖激酶活化剂。还包括组合物和治疗方法。

9. 发明申请

US20080036753A1 Display device and driving method thereof 有权
标题翻译：显示装置及其驱动方法
公开(公告)号：US20080036753A1
公开(公告)日：2008-02-14
申请号：US11882533
申请日：2007-08-02
申请人： Hajime Washio , Yasuyoshi Kaise , Sachio Tsujino , Kazuhiro Maeda , Keiji Takahashi , Yasushi Kubota , Toshiya Aoki
发明人： Hajime Washio , Yasuyoshi Kaise , Sachio Tsujino , Kazuhiro Maeda , Keiji Takahashi , Yasushi Kubota , Toshiya Aoki
IPC分类号： G06F3/038
CPC分类号： G09G3/3688 , G09G3/3614 , G09G3/3648 , G09G3/3666 , G09G3/3677 , G09G2310/0213 , G09G2310/0232 , G09G2310/027 , G09G2310/0283 , G09G2310/0297 , G09G2310/04 , G09G2320/0214 , G09G2320/10 , G09G2330/021
摘要： An example control signal generating circuit CTL for controlling the writing into pixels PIX instructs a data signal line drive circuit SD2, which is for driving pixels in a non-display area, to write a voltage VB or a voltage VW which are for non-displaying, not only in the first frame but also once in a predetermined number of frames. In other words, the pixels in the display area are refreshed at intervals longer than those in the case of refreshing the pixels in each frame. Thus, even if the mobility of an active element is high and the leak current on the occasion of OFF-state is large, or even if a large amount of electric charge is accumulated because of the photoelectric effect due to the use of a backlight, it is possible to prevent unnecessary displaying on the display area, which is caused because the writing into the pixels in the display area influences on the pixels in the non-display area, and hence it is possible to improve the quality of partial displaying, while restraining the power consumption.
摘要翻译：用于控制写入像素PIX的示例性控制信号发生电路CTL指示用于驱动非显示区域中的像素的数据信号线驱动电路SD 2写入用于非显示区域的电压VB或电压VW，不仅在第一帧中显示，而且在预定数量的帧中显示一次。换句话说，显示区域中的像素以比刷新每帧中的像素的情况更长的间隔更新。因此，即使有源元件的迁移率高，关断状态下的漏电流大，或者即使由于使用背光导致的光电效应而累积大量的电荷，可以防止由于对显示区域中的像素的写入而影响非显示区域中的像素而导致的显示区域的不必要的显示，因此可以提高部分显示的质量，同时限制功耗。

10. 发明授权

US07230547B2 Indicator light apparatus of marine vessel 失效
标题翻译：船舶指示灯装置
公开(公告)号：US07230547B2
公开(公告)日：2007-06-12
申请号：US11074580
申请日：2005-03-07
申请人： Atsufumi Ozaki , Keiji Takahashi
发明人： Atsufumi Ozaki , Keiji Takahashi
IPC分类号： G08B23/00
CPC分类号： B63B45/00 , B60Q1/54 , B63H21/213
摘要： An indicator light apparatus of a marine vessel is provided. The indicator light apparatus includes a sensor for detecting a value related to a traveling speed of the marine vessel, an indicator light provided in the marine vessel, and a control device configured to change an illuminating pattern of the indicator light based on the value related to the traveling speed detected by the sensor.
摘要翻译：提供船舶的指示灯装置。指示灯装置包括用于检测与船舶的行进速度相关的值的传感器，设置在船舶中的指示灯，以及控制装置，其被配置为基于与指示灯相关的值来改变指示灯的照明图案传感器检测到的行驶速度。

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